Documents in category 'Protein Structures' (pdb)

Crystal structure of an oligomer of proteolytic zymogens: detailed conformational analysis of the bovine ternary complex and implications for their activation 1 1 Edited by I. A. Wilson
score: 7.6032217, Journal of Molecular Biology, 1997, Gomis-Rüth, F.X et. al.

Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface.
score: 7.6021405, Proceedings of the National Academy of Sciences of the United States of America, 2012, Emptage, Ryan P et. al.

Complex assembly mechanism and an RNA-binding mode of the human p14-SF3b155 spliceosomal protein complex identified by NMR solution structure and functional analyses.
score: 7.392216, Proteins, 2008, Kuwasako, Kanako et. al.

A comparison of BRCT domains involved in nonhomologous end-joining: Introducing the solution structure of the BRCT domain of polymerase lambda
score: 7.3632587, DNA Repair, 2008, Mueller, Geoffrey A. et. al.

Recognition and Detoxification of the Insecticide DDT by Drosophila melanogaster Glutathione S-Transferase D1
score: 7.2085612, Journal of Molecular Biology, 2010, Low, Wai Yee et. al.

The crystal structure of d-glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeon Methanothermus fervidus in the presence of NADP + at 2.1 Å resolution 1 1 Edited by R. Huber
score: 7.1778625, Journal of Molecular Biology, 2000, Charron, C et. al.

Functional significance of four successive glycine residues in the pyrophosphate binding loop of fungal 6-oxopurine phosphoribosyltransferases.
score: 6.9337603, Protein science : a publication of the Protein Society, 2012, Moynié, Lucile et. al.

HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues.
score: 6.8695281, Nature structural & molecular biology, 2010, Krojer, Tobias; Sawa, Justyna; Huber, Robert; Clausen, Tim

X-ray structure of a hydroxamate inhibitor complex of stromelysin catalytic domain and its comparison with members of the zinc metalloproteinase superfamily
score: 6.7096861, Structure, 1996, Dhanaraj, V et. al.

Crystallization and structure determination of a hepatitis delta virus ribozyme: use of the RNA-binding protein U1A as a crystallization module 1 1 Edited by D. C. Rees
score: 6.6994347, Journal of Molecular Biology, 2000, Ferré-D’Amaré, Adrian R.; Doudna, Jennifer A.

Structural insights into Atg10-mediated formation of the autophagy-essential Atg12-Atg5 conjugate
score: 6.6296216, Structure, 2012, Yamaguchi, Masaya et. al.

The structure of human Argonaute-2 in complex with miR-20a
score: 6.5898766, Cell, 2012, Elkayam, Elad et. al.

The crystal structure of thymidylate synthase from Pneumocystis carinii reveals a fungal insert important for drug design 1 1 Edited by I. A. Wilson
score: 6.5101462, Journal of Molecular Biology, 2000, Anderson, Amy C et. al.

Crystal structure of the glycosyltransferase SnogD from the biosynthetic pathway of nogalamycin in Streptomyces nogalater.
score: 6.4508887, The FEBS journal, 2012, Claesson, Magnus et. al.

The Crystal Structure of the Human (S100A8/S100A9) 2 Heterotetramer, Calprotectin, Illustrates how Conformational Changes of Interacting α-Helices Can Determine Specific Association of Two EF-hand Proteins
score: 6.4128324, Journal of Molecular Biology, 2007, Korndörfer, Ingo P.; Brueckner, Florian; Skerra, Arne

Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor
score: 6.400848, BMC Structural Biology, 2012, Argiriadi, Maria A et. al.

The crystal structure of asparaginyl-tRNA synthetase from Thermus thermophilus and its complexes with ATP and asparaginyl-adenylate: the mechanism of discrimination between asparagine and aspartic acid.
score: 6.398097, The EMBO journal, 1998, Berthet-Colominas, C et. al.

The 1.15 Å Crystal Structure of the Staphylococcus aureus Methionyl-aminopeptidase and Complexes with Triazole Based Inhibitors
score: 6.3887539, Journal of Molecular Biology, 2003, Oefner, Christian et. al.

One Target—Two Different Binding Modes: Structural Insights into Gevokizumab and Canakinumab Interactions to Interleukin-1β
score: 6.3761876, Journal of Molecular Biology, 2013, Blech, Michaela et. al.

Solution structure and biophysical properties of MqsA, a Zn-containing antitoxin from Escherichia coli
score: 6.3673353, BBA - Proteins and Proteomics, 2012, Papadopoulos, Evangelos et. al.

Solution structure and biophysical properties of MqsA, a Zn-containing antitoxin from Escherichia coli
score: 6.3673353, BBA - Proteins and Proteomics, 2012, Papadopoulos, Evangelos et. al.

The Structure of a Bacterial Cellobiohydrolase: The Catalytic Core of theThermobifida fuscaFamily GH6 Cellobiohydrolase Cel6B
score: 6.364095, Journal of Molecular Biology, 2013, Sandgren, Mats et. al.

Structural Features of Human Initiation Factor 4E, Studied by X-ray Crystal Analyses and Molecular Dynamics Simulations
score: 6.3624438, Journal of Molecular Biology, 2003, Tomoo, Koji et. al.

Selective Removal of Individual Disulfide Bonds within a Potato Type II Serine Proteinase Inhibitor from Nicotiana alata Reveals Differential Stabilization of the Reactive-Site Loop
score: 6.2884208, Journal of Molecular Biology, 2010, Schirra, Horst Joachim et. al.

Solution structure of the Zbeta domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNAs.
score: 6.2882832, Proceedings of the National Academy of Sciences of the United States of America, 2011, Kim, Kyungmin et. al.

Structural Basis of m 7GpppG Binding to Poly(A)-Specific Ribonuclease
score: 6.2860285, Structure, 2009, Wu, Mousheng et. al.

Crystal Structure of Glucose-6-Phosphate Isomerase from Thermus thermophilus HB8 Showing a Snapshot of Active Dimeric State † † H.Y. performed structural determination and biochemical and biophysical experiments, and wrote this paper. H.M. contributed to large-scale protein production. N.K. supervised this work.
score: 6.2816047, Journal of Molecular Biology, 2008, Yamamoto, Hitoshi; Miwa, Hiroshi; Kunishima, Naoki

Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers
score: 6.2341779, BBA - General Subjects, 2012, Arai, Hiromi; Glabe, Charles; Luecke, Hartmut

Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers
score: 6.2341779, BBA - General Subjects, 2012, Arai, Hiromi; Glabe, Charles; Luecke, Hartmut

Structure and Function of ∆1-Tetrahydrocannabinolic Acid (THCA) Synthase, the Enzyme Controlling the Psychoactivity of Cannabissativa
score: 6.1958627, Journal of Molecular Biology, 2012, Shoyama, Yoshinari et. al.

An Integrated Platform for Automated Analysis of Protein NMR Structures
score: 6.1883244, Methods in Enzymology, 2005, Huang, Yuanpeng Janet et. al.

An Integrated Platform for Automated Analysis of Protein NMR Structures
score: 6.1883244, Methods in Enzymology, 2005, Huang, Yuanpeng Janet et. al.

Crystal Structure Analysis of the PHD Domain of the Transcription Co-activator Pygopus
score: 6.1699601, Journal of Molecular Biology, 2007, Nakamura, Yoshihiro et. al.

Structural switching of Cu,Zn-superoxide dismutases at loop VI: insights from the crystal structure of 2-mercaptoethanol-modified enzyme
score: 6.1578667, Bioscience Reports, 2012, Ihara, Kentaro et. al.

Structural basis for the alteration of coenzyme specificity in a malate dehydrogenase mutant
score: 6.1510115, Biochemical and Biophysical Research Communications, 2006, Tomita, Takeo et. al.

Crystal Structure of the N-Terminal Domain of Nup358/RanBP2
score: 6.1500287, Journal of Molecular Biology, 2012, Kassube, Susanne A. et. al.

Crystal Structure of the N-Terminal Domain of Nup358/RanBP2
score: 6.1500287, Journal of Molecular Biology, 2012, Kassube, Susanne A. et. al.

Recognition of Anesthetic Barbiturates by a Protein Binding Site: A High Resolution Structural Analysis
score: 6.1489112, PLoS ONE, 2012, Oakley, Simon et. al.

Crystal structure of decameric 2-Cys peroxiredoxin from human erythrocytes at 1.7Å resolution
score: 6.1189204, Structure, 2000, Schröder, Ewald et. al.

Crystal structure of Pyrococcus horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase
score: 6.1037021, Nucleic Acids Research, 2009, Dong, Xianchi et. al.

Insights into the Catalytic Mechanism of 16S rRNA Methyltransferase RsmE (m3U1498) from Crystal and Solution Structures
score: 6.0994099, Journal of Molecular Biology, 2012, Zhang, Heng et. al.

Insights into the Catalytic Mechanism of 16S rRNA Methyltransferase RsmE (m3U1498) from Crystal and Solution Structures
score: 6.0994099, Journal of Molecular Biology, 2012, Zhang, Heng et. al.

Solution Structure of CCP Modules 10–12 Illuminates Functional Architecture of the Complement Regulator, Factor H
score: 6.0904848, Journal of Molecular Biology, 2012, Makou, Elisavet et. al.

Solution Structure of CCP Modules 10–12 Illuminates Functional Architecture of the Complement Regulator, Factor H
score: 6.0904848, Journal of Molecular Biology, 2012, Makou, Elisavet et. al.

Solution Structure of CCP Modules 10–12 Illuminates Functional Architecture of the Complement Regulator, Factor H
score: 6.0904848, Journal of Molecular Biology, 2012, Makou, Elisavet et. al.

Insights into substrate binding by D -2-ketoacid dehydrogenases from the structure of Lactobacillus pentosus D -lactate dehydrogenase
score: 6.0880511, Structure, 1996, Stoll, Vincent S; Kimber, Matthew S; Pai, Emil F

Structure Determination and Functional Analysis of a Chromate Reductase from Gluconacetobacter hansenii
score: 6.0834256, PLoS ONE, 2012, Jin, Hongjun et. al.

Structural and functional insights into lipid-bound nerve growth factors.
score: 6.0527641, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Tong, Qiong et. al.

Structural characterization and inhibition of the Plasmodium Atg8–Atg3 interaction
score: 6.0163237, Journal of Structural Biology, 2012, Hain, Adelaide U.P. et. al.

Structural characterization and inhibition of the Plasmodium Atg8–Atg3 interaction
score: 6.0163237, Journal of Structural Biology, 2012, Hain, Adelaide U.P. et. al.

The Crystal Structure of the Catalytic Domain of the NF-κB Inducing Kinase Reveals a Narrow but Flexible Active Site
score: 6.0047678, Structure, 2012, de Leon-Boenig, Gladys et. al.

The Crystal Structure of the Catalytic Domain of the NF-κB Inducing Kinase Reveals a Narrow but Flexible Active Site
score: 6.0047678, Structure, 2012, de Leon-Boenig, Gladys et. al.

Crystal structure of the Bruton’s tyrosine kinase PH domain with phosphatidylinositol
score: 6.0000676, Biochemical and Biophysical Research Communications, 2008, Murayama, Kazutaka et. al.

Structural Insights into Ribosome Recycling Factor Interactions with the 70S Ribosome
score: 5.9778176, Journal of Molecular Biology, 2008, Pai, Raj D. et. al.

Crystal Structure of Cucumisin, a Subtilisin-Like Endoprotease from Cucumis melo L.
score: 5.9556106, Journal of Molecular Biology, 2012, Murayama, Kazutaka et. al.

Crystal Structure of Myeloid Cell Activating Receptor Leukocyte Ig-like Receptor A2 (LILRA2/ILT1/LIR-7) Domain Swapped Dimer: Molecular Basis for Its Non-binding to MHC Complexes
score: 5.949435, Journal of Molecular Biology, 2009, Chen, Yong et. al.

Dimeric Crystal Structure of Rabbit l-Gulonate 3-Dehydrogenase/λ-Crystallin: Insights into the Catalytic Mechanism
score: 5.9175815, Journal of Molecular Biology, 2010, Asada, Yukuhiko et. al.

Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2
score: 5.8913403, Structure, 2012, Erdemli, Sabri B. et. al.

Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2
score: 5.8913403, Structure, 2012, Erdemli, Sabri B. et. al.

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis.
score: 5.8880038, Proceedings of the National Academy of Sciences of the United States of America, 2009, Belin, Pascal et. al.

Tetrahydrodipicolinate N-Succinyltransferase and Dihydrodipicolinate Synthase from Pseudomonas aeruginosa : Structure Analysis and Gene Deletion
score: 5.8767186, PLoS ONE, 2012, Schnell, Robert et. al.

NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein
score: 5.8662277, Journal of Molecular Biology, 2012, Oeemig, Jesper S. et. al.

NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein
score: 5.8662277, Journal of Molecular Biology, 2012, Oeemig, Jesper S. et. al.

RANKL employs distinct binding modes to engage RANK and the OPG decoy receptor
score: 5.863592, Structure, 2012, Nelson, Christopher A. et. al.

Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis
score: 5.8618739, Cell, 2013, Czabotar, Peter E. et. al.

Intrinsic Dynamics of an Extended Hydrophobic Core in theS.cerevisiaeRNase III dsRBD Contributes to Recognition of Specific RNA Binding Sites
score: 5.8534113, Journal of Molecular Biology, 2013, Hartman, Elon et. al.

NMR and crystalstructures of the Pyrococcus horikoshii RadA intein guide a strategy for engineering a highly efficient and promiscuous intein
score: 5.8360601, Journal of Molecular Biology, 2012, Oeemig, Jesper S. et. al.

Crystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLP.
score: 5.8240564, The FEBS journal, 2012, Humble, Maria S et. al.

Kinase Domain Insertions Define Distinct Roles of CLK Kinases in SR Protein Phosphorylation
score: 5.8232765, Structure, 2009, Bullock, Alex N. et. al.

The Inherent Properties of DNA Four-way Junctions: Comparing the Crystal Structures of Holliday Junctions
score: 5.7888998, Journal of Molecular Biology, 2002, Eichman, Brandt F. et. al.

NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein
score: 5.7542918, Journal of Molecular Biology, 2012, Oeemig, Jesper S. et. al.

Structural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL Domain Phosphodiesterases
score: 5.7516583, Journal of Molecular Biology, 2010, Tchigvintsev, Anatoli et. al.

Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases
score: 5.7381387, Cell, 1997, Hon, Wai-Ching et. al.

The Structure of Human Argonaute-2 in Complex with miR-20a
score: 5.7213625, Cell, 2012, Elkayam, Elad et. al.

Crystal structure of the N-terminal domain of Geobacillus kaustophilus HTA426 DnaD protein
score: 5.6995276, Biochemical and Biophysical Research Communications, 2008, Huang, Cheng-Yang; Chang, Yi-Wei; Chen, Wei-Ti

Crystal structure of unliganded TRAP: implications for dynamic allostery
score: 5.6962112, Biochemical Journal, 2010, Malay, Ali D. et. al.

The Structure of Human Argonaute-2 in Complex with miR-20a
score: 5.6899656, Cell, 2012, Elkayam, Elad et. al.

Kinase Domain Insertions Define Distinct Roles of CLK Kinases in SR Protein Phosphorylation
score: 5.6761353, Structure (London, England : 1993), 2009, Bullock, Alex N. et. al.

The importance of the trans-enamine intermediate as a β-lactamase inhibition strategy probed in inhibitor-resistant SHV β-lactamase variants.
score: 5.6751427, ChemMedChem, 2012, Ke, Wei et. al.

Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor
score: 5.6736643, BMC Structural Biology, 2010, Garau, Gianpiero et. al.

Lipid Molecules Induce p38αActivation via a Novel Molecular Switch
score: 5.6728226, Journal of Molecular Biology, 2012, Tzarum, Netanel et. al.

Role of remote scaffolding residues in the inhibitory loop pre-organisation, flexibility, rigidification and enzyme inhibition of serine protease inhibitors
score: 5.6722066, BBA - Proteins and Proteomics, 2012, Majumder, Sudip et. al.

Crystal structure of a new RNA-binding domain from the antiterminator protein SacY of Bacillus subtilis.
score: 5.6676214, The EMBO journal, 1997, van Tilbeurgh, H et. al.

Molecular Basis for Nucleotide-binding Specificity: Role of the Exocyclic Amino Group “N2” in Recognition by a Guanylyl-ribonuclease
score: 5.6582254, Journal of Molecular Biology, 2006, Schrift, Greta L. et. al.

Crystal Structures of the HypCD Complex and the HypCDE Ternary Complex: Transient Intermediate Complexes during [NiFe] Hydrogenase Maturation
score: 5.6572999, Structure, 2012, Watanabe, Satoshi et. al.

Crystal Structures of the HypCD Complex and the HypCDE Ternary Complex: Transient Intermediate Complexes during [NiFe] Hydrogenase Maturation
score: 5.6572999, Structure, 2012, Watanabe, Satoshi et. al.

Comparative Structuraland Functional Studies of 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidine-5-carbonitrileCDK9 Inhibitors Suggest the Basis for Isotype Selectivity
score: 5.64895, Journal of Medicinal Chemistry, 2012, Hole, Alison J. et. al.

The Role of the β5–α11 Loop in the Active-Site Dynamics of Acylated Penicillin-Binding Protein A from Mycobacterium tuberculosis
score: 5.6288602, Journal of Molecular Biology, 2012, Fedarovich, Alena; Nicholas, Robert A.; Davies, Christopher

Structural Basis of DNA Loop Recognition by Endonuclease V
score: 5.6241254, Structure, 2013, Rosnes, Ida et. al.

Structural and biochemical characterization of a novel Mn2+-dependent phosphodiesterase encoded by the yfcE gene.
score: 5.5969205, Protein science : a publication of the Protein Society, 2007, Miller, Darcie J et. al.

Two Structurally Atypical HEAT Domains in the C-Terminal Portion of Human eIF4G Support Binding to eIF4A and Mnk1
score: 5.59677, Structure, 2006, Bellsolell, Lluís et. al.

Two Structurally Atypical HEAT Domains in the C-Terminal Portion of Human eIF4G Support Binding to eIF4A and Mnk1
score: 5.59677, Structure, 2006, Bellsolell, Lluís et. al.

The oligomerization domain of p53: Crystal structure of the trigonal form
score: 5.5712245, FEBS Letters, 1996, Miller, Maria et. al.

Structure of an Asymmetric Ternary Protein Complex Provides Insight for Membrane Interaction
score: 5.5693141, Structure, 2012, Dempsey, Brian R. et. al.

Structure of an Asymmetric Ternary Protein Complex Provides Insight for Membrane Interaction
score: 5.5693141, Structure, 2012, Dempsey, Brian R. et. al.

Crystal structure of human mitochondrial NAD(P) +-dependent malic enzyme: a new class of oxidative decarboxylases
score: 5.568017, Structure, 1999, Xu, Yingwu et. al.

Structural Basis for ASPP2 Recognition by the Tumor Suppressor p73
score: 5.5679247, Journal of Molecular Biology, 2012, Canning, Peter; von Delft, Frank; Bullock, Alex N.

Structural Basis for ASPP2 Recognition by the Tumor Suppressor p73
score: 5.5679247, Journal of Molecular Biology, 2012, Canning, Peter; von Delft, Frank; Bullock, Alex N.

Bacterial and plant ketol-acid reductoisomerases have different mechanisms of induced fit during the catalytic cycle
score: 5.5650668, Journal of Molecular Biology, 2012, Wong, Sze-Ho et. al.

Structural Basis for the Substrate Specificity of Bone Morphogenetic Protein 1/Tolloid-like Metalloproteases
score: 5.559101, Journal of Molecular Biology, 2008, Mac Sweeney, A. et. al.

Structural Basis for Activation of ARF GTPase
score: 5.5141881, Cell, 1998, Goldberg, Jonathan

Structural Insights into Atg10-Mediated Formation of the Autophagy-Essential Atg12-Atg5 Conjugate
score: 5.508833, Structure, 2012, Yamaguchi, Masaya et. al.

Structural Insights into Atg10-Mediated Formation of the Autophagy-Essential Atg12-Atg5 Conjugate
score: 5.508833, Structure, 2012, Yamaguchi, Masaya et. al.

The Binding Site of Acetylcholine Receptor as Visualized in the X-Ray Structure of a Complex between α-Bungarotoxin and a Mimotope Peptide
score: 5.4962602, Neuron, 2001, Harel, Michal et. al.

Structural Characterization of an LPA 1 Second Extracellular Loop Mimetic with a Self-Assembling Coiled-Coil Folding Constraint
score: 5.4862365, International Journal of Molecular Sciences, 2013, Young, John K. et. al.

Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases
score: 5.4782712, Structure, 2013, Krishnan, Swathi; Trievel, Raymond C.

Mapping the Phosphoinositide-Binding Site on Chick Cofilin Explains How PIP 2 Regulates the Cofilin-Actin Interaction
score: 5.4669953, Molecular Cell, 2006, Gorbatyuk, Vitaliy Y. et. al.

Crystal structure of cholesterol oxidase from Brevibacterium sterolicum refined at 1.8 Å resolution
score: 5.4509218, Journal of Molecular Biology, 1991, Vrielink, Alice; Lloyd, Lesley F; Blow, David M

The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation
score: 5.4401505, Cell, 2012, Itsathitphaisarn, Ornchuma et. al.

The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation
score: 5.4401505, Cell, 2012, Itsathitphaisarn, Ornchuma et. al.

Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor
score: 5.4396737, Cell, 1996, Eck, Michael J. et. al.

Crystal Structure of the Klebsiella pneumoniae NFeoB/FeoC Complex and Roles of FeoC in Regulation of Fe2+ Transport by the Bacterial Feo System.
score: 5.4341641, Journal of bacteriology, 2012, Hung, Kuo-Wei et. al.

Crystal Structures of Two Aminoglycoside Kinases Bound with a Eukaryotic Protein Kinase Inhibitor
score: 5.433307, PLoS ONE, 2011, Fong, Desiree H. et. al.

A New Solution Structure of ATP Synthase Subunit c from Thermophilic Bacillus PS3, Suggesting a Local Conformational Change for H +-Translocation
score: 5.4271026, Journal of Molecular Biology, 2006, Nakano, Takayuki et. al.

Quantitative Evaluation of Each Catalytic Subsite of Cathepsin B for Inhibitory Activity Based on Inhibitory Activity–Binding Mode Relationship of Epoxysuccinyl Inhibitors by X-ray Crystal Structure Analyses of Complexes
score: 5.4269079, Journal of Molecular Biology, 2006, Watanabe, Daiya et. al.

The crystal structure of the cysteine protease Xylellain fromXylella fastidiosareveals an intriguing activation mechanism
score: 5.4257532, FEBS Letters, 2013, Leite, Ney Ribeiro et. al.

Crystal structure of an aerobic FMN-dependent azoreductase (AzoA) from Enterococcus faecalis
score: 5.4230341, Archives of Biochemistry and Biophysics, 2007, Liu, Zhi-Jie et. al.

Structural Insight into the Recognition of the H3K4me3 Mark by the TFIID Subunit TAF3
score: 5.4056914, Structure, 2008, van Ingen, Hugo et. al.

The “Phantom Effect” of the Rexinoid LG100754: Structural and Functional Insights
score: 5.3989656, PLoS ONE, 2010, Sato, Yoshiteru et. al.

Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors
score: 5.3776432, BBA - Proteins and Proteomics, 2012, Majumder, Sudip et. al.

Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors
score: 5.3776432, BBA - Proteins and Proteomics, 2012, Majumder, Sudip et. al.

Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors
score: 5.3776432, BBA - Proteins and Proteomics, 2012, Majumder, Sudip et. al.

Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor.
score: 5.3770547, Proceedings of the National Academy of Sciences of the United States of America, 2012, Jiang, Xuliang et. al.

Lipid Molecules Induce p38α Activation via a Novel Molecular Switch
score: 5.3726852, Journal of Molecular Biology, 2012, Tzarum, Netanel et. al.

Lipid Molecules Induce p38α Activation via a Novel Molecular Switch
score: 5.3726852, Journal of Molecular Biology, 2012, Tzarum, Netanel et. al.

Lipid Molecules Induce p38α Activation via a Novel Molecular Switch
score: 5.3726852, Journal of Molecular Biology, 2012, Tzarum, Netanel et. al.

Solution Structure of an Archaeal DNA Binding Protein with an Eukaryotic Zinc Finger Fold
score: 5.3704513, PLoS ONE, 2013, Guillière, Florence et. al.

Structural basis for catalytic activity of a silkworm Delta-class glutathione transferase
score: 5.3627036, BBA - General Subjects, 2012, Yamamoto, Kohji et. al.

Structural basis for catalytic activity of a silkworm Delta-class glutathione transferase
score: 5.3627036, BBA - General Subjects, 2012, Yamamoto, Kohji et. al.

Structural basis for engagement by complement factor H of C3b on a self surface.
score: 5.3516246, Nature structural & molecular biology, 2011, Morgan, Hugh P et. al.

Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum
score: 5.3425066, Scientific Reports, 2011, Umeda, Tomonobu et. al.

Crystal structure of HsEg5 in complex with clinical candidate CK0238273 provides insight into inhibitory mechanism, potency, and specificity
score: 5.3281952, Biochemical and Biophysical Research Communications, 2008, Zhang, Bin; Liu, Ji-Feng; Xu, Yingwu; Ng, Shi-Chung

Three-dimensional structure of the diphtheria toxin repressor in complex with divalent cation co-repressors
score: 5.3249334, Structure, 1995, Qiu, Xiayang et. al.

Ligand-induced structural changes to maltodextrin-binding protein as studied by solution NMR spectroscopy 1 1 Edited by P. E. Wright
score: 5.3222302, Journal of Molecular Biology, 2001, Evenäs, Johan et. al.

Structural Studies on Flavodiiron Proteins
score: 5.3220481, Methods in Enzymology, 2008, Vicente, João B. et. al.

The Tertiary Structure and Backbone Dynamics of Human Prolactin
score: 5.318095, Journal of Molecular Biology, 2003, Keeler, Camille; Dannies, Priscilla S.; Hodsdon, Michael E.

The X-ray structure of Escherichia coli enoyl reductase with bound NAD + at 2.1 Å resolution 1 1 Edited by R. Huber
score: 5.3118101, Journal of Molecular Biology, 1998, Baldock, Clair et. al.

Crystal structure of the C-terminal tetrad repeat from synexin (annexin VII) of Dictyostelium discoideum 1 1 Edited by A.R.Fersht
score: 5.301749, Journal of Molecular Biology, 1997, Liemann, Susanne et. al.

The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms
score: 5.2996036, Structure, 2012, Horjales, Sofía et. al.

The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms
score: 5.2996036, Structure, 2012, Horjales, Sofía et. al.

Structural Basis of the Role of the NikA Ribbon-Helix-Helix Domain in Initiating Bacterial Conjugation
score: 5.2939088, Journal of Molecular Biology, 2008, Yoshida, Hitoshi et. al.

Structure determination and refinement of bovine lens leucine aminopeptidase and its complex with bestatin
score: 5.292202, Journal of Molecular Biology, 1992, Burley, Stephen K. et. al.

Probing the Supramodular Architecture of a Multidomain Protein: The Structure of Syntenin in Solution
score: 5.2892666, Structure, 2005, Cierpicki, Tomasz et. al.

Dissecting the catalytic mechanism of a plant β- d-glucan glucohydrolase through structural biology using inhibitors and substrate analogues
score: 5.279656, Carbohydrate Research, 2007, Hrmova, Maria; Fincher, Geoffrey B.

Tryptophanyl-tRNA synthetase crystal structure reveals an unexpected homology to tyrosyl-tRNA synthetase
score: 5.2724895, Structure, 1995, Doublié, Sylvie et. al.

Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase
score: 5.2642451, Journal of Molecular Biology, 2012, Gouge, Jérôme et. al.

A glutamate switch controls voltage-sensitive phosphatase function
score: 5.2521692, Nature structural & molecular biology, 2012, Liu, Lijun et. al.

What is the average conformation of bacteriophage T4 lysozyme in solution? a domain orientation study using dipolar couplings measured by solution NMR 1 1 Edited by P. E. Wright
score: 5.2488182, Journal of Molecular Biology, 2001, Goto, Natalie K. et. al.

The crystal structure of the penicillin-binding protein 2x from Streptococcus pneumoniae and its acyl-enzyme form: implication in drug resistance 1 1 Edited by R. Huber
score: 5.2476257, Journal of Molecular Biology, 2000, Gordon, E.; Mouz, N.; Duée, E.; Dideberg, O.

A structural mechanism for dimeric to tetrameric oligomer conversion in Halomonas sp. nucleoside diphosphate kinase.
score: 5.2423144, Protein science : a publication of the Protein Society, 2012, Arai, Shigeki et. al.

Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding 1 1 Edited by I. A. Wilson
score: 5.2332472, Journal of Molecular Biology, 2000, Schumacher, Maria A et. al.

Structure-directed discovery of potent non-peptidic inhibitors of human urokinase that access a novel binding subsite
score: 5.2324353, Structure, 2000, Nienaber, Vicki L et. al.

Structure of the Human Cytomegalovirus Protease Catalytic Domain Reveals a Novel Serine Protease Fold and Catalytic Triad
score: 5.2204795, Cell, 1996, Chen, Ping et. al.

Using a Fragment-Based Approach To Target Protein–Protein Interactions
score: 5.2201856, Chembiochem, 2013, Scott, Duncan E et. al.

Structure of the heme/hemoglobin outer membrane receptor ShuA from Shigella dysenteriae: heme binding by an induced fit mechanism.
score: 5.215079, Proteins, 2010, Cobessi, David; Meksem, Ahmed; Brillet, Karl

The 2.4 Å resolution crystal structure of boar seminal plasma PSP-I/PSP-II: a zona pellucida-binding glycoprotein heterodimer of the spermadhesin family built by a CUB domain architecture 1 1 Edited by R. Huber
score: 5.2113172, Journal of Molecular Biology, 1997, Varela, Paloma F. et. al.

The Enzymology of alanine aminotransferase (AlaAT) isoforms from Hordeum vulgare and other organisms, and the HvAlaAT crystal structure
score: 5.2088421, Archives of Biochemistry and Biophysics, 2012, Duff, Stephen M.G. et. al.

The Enzymology of alanine aminotransferase (AlaAT) isoforms from Hordeum vulgare and other organisms, and the HvAlaAT crystal structure
score: 5.2088421, Archives of Biochemistry and Biophysics, 2012, Duff, Stephen M.G. et. al.

Determination of the three-dimensional structure of toxins by protein crystallography
score: 5.1980054, Toxicon, 2000, Souza, Dulce H.F. et. al.

NMR structure and dynamics of human ephrin-B2 ectodomain: the functionally critical C-D and G-H loops are highly dynamic in solution.
score: 5.193929, Proteins, 2008, Ran, Xiaoyuan et. al.

Structural analysis of an epsilon-class glutathione transferase from housefly,Musca domestica
score: 5.1919566, Biochemical and Biophysical Research Communications, 2013, Nakamura, Chihiro et. al.

Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1.
score: 5.1860743, Proceedings of the National Academy of Sciences of the United States of America, 2012, Wu, Hong et. al.

DNA Minor Groove Sensing and Widening by the CCAAT-Binding Complex
score: 5.1838752, Structure, 2012, Huber, Eva M. et. al.

DNA Minor Groove Sensing and Widening by the CCAAT-Binding Complex
score: 5.1838752, Structure, 2012, Huber, Eva M. et. al.

Crystal structure of human copper homeostasis protein CutC reveals a potential copper-binding site
score: 5.1835509, Journal of Structural Biology, 2010, Li, Yingjie; Du, Jiamu; Zhang, Peng; Ding, Jianping

Crystal Structure of the O2-Tolerant Membrane-Bound Hydrogenase 1 from Escherichia coli in Complex with Its Cognate Cytochrome b
score: 5.1817875, Structure, 2013, Volbeda, Anne et. al.

Crystal structures of acetate kinases from the eukaryotic pathogensEntamoeba histolyticaandCryptococcus neoformans
score: 5.1809833, Journal of Structural Biology, 2013, Thaker, Tarjani M. et. al.

Structure, dynamics and domain organization of the repeat protein Cin1 from the apple scab fungus
score: 5.1739646, BBA - Proteins and Proteomics, 2012, Mesarich, Carl H. et. al.

Structural basis for catalytic activity of a silkworm Delta-class glutathione transferase
score: 5.1695621, BBA - General Subjects, 2012, Yamamoto, Kohji et. al.

The substrate/product-binding modes of a novel GH120 β-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485
score: 5.1678539, Biochemical Journal, 2012, Huang, Chun-Hsiang et. al.

Exploring ribozyme conformational changes with X-ray crystallography
score: 5.1659252, Methods, 2009, Spitale, Robert C.; Wedekind, Joseph E.

Crystal structures of influenza virus hemagglutinin in complex with high-affinity receptor
score: 5.1652051, Structure, 1994, Watowich, Stanley J; Skehel, John J; Wiley, Don C

Substrate Recognition Mechanism of Atypical Protein Kinase Cs Revealed by the Structure of PKCι in Complex with a Substrate Peptide from Par-3
score: 5.1622348, Structure, 2012, Wang, Chihao; Shang, Yuan; Yu, Jiang; Zhang, Mingjie

Structural basis for intersubunit signaling in a protein disaggregating machine.
score: 5.1598541, Proceedings of the National Academy of Sciences of the United States of America, 2012, Biter, Amadeo B et. al.

Crystal structure of a covalent intermediate in DNA cleavage and rejoining by Escherichia coli DNA topoisomerase I.
score: 5.1550016, Proceedings of the National Academy of Sciences of the United States of America, 2011, Zhang, Zhongtao; Cheng, Bokun; Tse-Dinh, Yuk-Ching

Crystal Structure Of The Filamin N-Terminal Region Reveals A Hinge Between The Actin Binding And First Repeat Domains
score: 5.1488429, Journal of Molecular Biology, 2012, Sawyer, Gregory M.; Sutherland-Smith, Andrew J.

Assessing the range of kinase autoinhibition mechanisms in the insulin receptor family
score: 5.1444139, Biochemical Journal, 2012, Artim, Stephen C.; Mendrola, Jeannine M.; Lemmon, Mark A.

Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection
score: 5.139613, Structure, 2012, Koh, Cho Yeow et. al.

Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection
score: 5.139613, Structure, 2012, Koh, Cho Yeow et. al.

Coevolution of Antibody Stability and Vκ CDR-L3 Canonical Structure
score: 5.1368853, Journal of Molecular Biology, 2010, Luo, Jinquan et. al.

Biosynthesis of the 22nd Genetically Encoded Amino Acid Pyrrolysine: Structure and Reaction Mechanism of PylC at 1.5Å Resolution
score: 5.1307768, Journal of Molecular Biology, 2012, Quitterer, Felix et. al.

The Structure of Human GALNS Reveals the Molecular Basis for Mucopolysaccharidosis IV A
score: 5.1303839, Journal of Molecular Biology, 2012, Rivera-Colón, Yadilette et. al.

The Structure of Human GALNS Reveals the Molecular Basis for Mucopolysaccharidosis IV A
score: 5.1303839, Journal of Molecular Biology, 2012, Rivera-Colón, Yadilette et. al.

Crystal structure of a sweet tasting protein thaumatin I, at 1·65 Å resolution
score: 5.1258238, Journal of Molecular Biology, 1992, Ogata, Craig M. et. al.

Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3′-splice site recognition
score: 5.1203485, Nucleic Acids Research, 2012, Zhang, Yun et. al.

Biosynthesis of the 22nd Genetically Encoded Amino Acid Pyrrolysine: Structure and Reaction Mechanism of PylC at 1.5Å Resolution
score: 5.1151516, Journal of Molecular Biology, 2012, Quitterer, Felix et. al.

Biosynthesis of the 22nd Genetically Encoded Amino Acid Pyrrolysine: Structure and Reaction Mechanism of PylC at 1.5Å Resolution
score: 5.1151516, Journal of Molecular Biology, 2012, Quitterer, Felix et. al.

Structure and Catalytic Mechanism of a Cyclic Dipeptide Prenyltransferase with Broad Substrate Promiscuity
score: 5.1151501, Journal of Molecular Biology, 2012, Schuller, Jan Michael et. al.

Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage.
score: 5.1144269, Journal of virology, 2012, Lu, Xishan et. al.

Structural and Biochemical Characterization of the Therapeutic Anabaena variabilis Phenylalanine Ammonia Lyase
score: 5.1108017, Journal of Molecular Biology, 2008, Wang, Lin et. al.

Insights into the Aberrant Activity of Mutant EGFR Kinase Domain and Drug Recognition
score: 5.1103571, Structure, 2013, Gajiwala, Ketan S. et. al.

Insights into the Aberrant Activity of Mutant EGFR Kinase Domain and Drug Recognition
score: 5.1103571, Structure, 2013, Gajiwala, Ketan S. et. al.

X-ray structure of a functional full-length dynein motor domain.
score: 5.1071645, Nature structural & molecular biology, 2011, Kon, Takahide; Sutoh, Kazuo; Kurisu, Genji

Structural Basis of BACH1 Phosphopeptide Recognition by BRCA1 Tandem BRCT Domains
score: 5.1046462, Structure, 2004, Botuyan, Maria Victoria E et. al.

Refined structure of elongation factor EF-Tu from Escherichia coli
score: 5.0935783, Journal of Molecular Biology, 1992, Kjeldgaard, Morten; Nyborg, Jens

An Unusual Role for a Mobile Flavin in StaC-like Indolocarbazole Biosynthetic Enzymes
score: 5.091127, Chemistry & Biology, 2012, Goldman, Peter J. et. al.

N-(4-Substituted-benzoyl)-N′-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods
score: 5.0910982, Bioorganic & Medicinal Chemistry, 2012, Nagy, Veronika et. al.

Interpreting a Low Resolution Map of Human U1 snRNP Using Anomalous Scatterers
score: 5.0903343, Structure, 2009, Oubridge, Chris et. al.

Structural analysis of an epsilon-class glutathione transferase from housefly,Musca domestica
score: 5.0881287, Biochemical and Biophysical Research Communications, 2013, Nakamura, Chihiro et. al.

Structural analysis of an epsilon-class glutathione transferase from housefly,Musca domestica
score: 5.0881287, Biochemical and Biophysical Research Communications, 2013, Nakamura, Chihiro et. al.

Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium
score: 5.0841795, Journal of Structural Biology, 2012, Qiu, Xiaoting et. al.

Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium
score: 5.0841795, Journal of Structural Biology, 2012, Qiu, Xiaoting et. al.

Three-dimensional structure of a mutant ribonuclease T 1 (Y45W) complexed with non-cognizable ribonucleotide, 2′AMP, and its comparison with a specific complex with 2′GMP
score: 5.0639548, Journal of Molecular Biology, 1992, Hakoshima, Toshio et. al.

Sialylation of the host receptor may modulate entry of demyelinating persistent Theiler's virus.
score: 5.0572334, Journal of virology, 2000, Zhou, L; Luo, Y; Wu, Y; Tsao, J; Luo, M

UV damage endonuclease employs a novel dual-dinucleotide flipping mechanism to recognize different DNA lesions
score: 5.0526271, Nucleic Acids Research, 2012, Meulenbroek, Elisabeth M. et. al.

Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2
score: 5.0440803, FEBS Letters, 2010, Umehara, Takashi et. al.

Probing Interactions of Tubulin with Small Molecules, Peptides, and Protein Fragments by Solution Nuclear Magnetic Resonance
score: 5.0436873, Methods in Cell Biology, 2010, Clément, Marie-Jeanne et. al.

Biochemical properties and crystal structure of a β-phenylalanine aminotransferase from Variovorax paradoxus.
score: 5.0408922, Applied and environmental microbiology, 2012, Crismaru, Ciprian G et. al.

The Archaeal sRNA Binding Protein L7Ae has a 3D Structure Very Similar to that of its Eukaryal Counterpart While Having a Broader RNA-binding Specificity
score: 5.036917, Journal of Molecular Biology, 2004, Charron, C. et. al.

The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes.
score: 5.0297027, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Liang, Lianming et. al.

Structural Basis of the Initial Binding of tRNA Ile Lysidine Synthetase TilS with ATP and L-Lysine
score: 5.0291283, Structure, 2007, Kuratani, Mitsuo et. al.

Solution structure of the core SMN–Gemin2 complex
score: 5.0284937, Biochemical Journal, 2012, Sarachan, Kathryn L. et. al.

Structure and DNA binding characteristics of the three-Cys(2)His(2) domain of mouse testis zinc finger protein.
score: 5.0197067, Proteins, 2010, Chou, Chun-Chi; Lou, Yuan-Chao; Tang, Tang K; Chen, Chinpan

The crystal and molecular structure of the Rhizomucor miehei triacylglyceride lipase at 1.9 Å resolution
score: 5.0185148, Journal of Molecular Biology, 1992, Derewenda, Zygmunt S.; Derewenda, Urszula; Dodson, Guy G.

Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel
score: 5.016689, Journal of Molecular Biology, 2012, Marques-Carvalho, Maria J. et. al.

Bacterial and Plant Ketol-Acid Reductoisomerases Have Different Mechanisms of Induced Fit during the Catalytic Cycle
score: 5.0159617, Journal of Molecular Biology, 2012, Wong, Sze-Ho et. al.

Bacterial and Plant Ketol-Acid Reductoisomerases Have Different Mechanisms of Induced Fit during the Catalytic Cycle
score: 5.0159617, Journal of Molecular Biology, 2012, Wong, Sze-Ho et. al.

Bacterial and Plant Ketol-Acid Reductoisomerases Have Different Mechanisms of Induced Fit during the Catalytic Cycle
score: 5.0159617, Journal of Molecular Biology, 2012, Wong, Sze-Ho et. al.

Sulfonation of glycopeptide antibiotics by sulfotransferase StaL depends on conformational flexibility of aglycone scaffold.
score: 5.0098998, Proceedings of the National Academy of Sciences of the United States of America, 2012, Shi, Rong et. al.

Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq
score: 5.0054058, Nucleic Acids Research, 2011, Someya, Tatsuhiko et. al.

The RRM domain of human fused in sarcoma protein reveals a non-canonical nucleic acid binding site
score: 5.0017012, BBA - Molecular Basis of Disease, 2013, Liu, Xuehui et. al.

The RRM domain of human fused in sarcoma protein reveals a non-canonical nucleic acid binding site
score: 5.0017012, BBA - Molecular Basis of Disease, 2013, Liu, Xuehui et. al.

The Crystal Structure of the Dachshund Domain of Human SnoN Reveals Flexibility in the Putative Protein Interaction Surface
score: 4.9922864, PLoS ONE, 2010, Nyman, Tomas et. al.

Structural Characterization of Binding Mode of Smoking Cessation Drugs to Nicotinic Acetylcholine Receptors through Study of Ligand Complexes with Acetylcholine-binding Protein *
score: 4.9916323, The Journal of Biological Chemistry, 2012, Rucktooa, Prakash et. al.

Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein: Fatty Acid Binding Revisited
score: 4.9913729, Biophysical Journal, 2012, Cai, Jun et. al.

The NOXO1β PX Domain Preferentially Targets PtdIns(4,5)P2 and PtdIns(3,4,5)P3
score: 4.9852965, Journal of Molecular Biology, 2012, Davis, Nicole Y.; McPhail, Linda C.; Horita, David A.

Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein: Fatty Acid Binding Revisited
score: 4.9846384, Biophysical Journal, 2012, Cai, Jun et. al.

Structure of a High-affinity “Mimotope” Peptide Bound to HIV-1-neutralizing Antibody b12 Explains its Inability to Elicit gp120 Cross-reactive Antibodies
score: 4.9845327, Journal of Molecular Biology, 2007, Saphire, Erica Ollmann et. al.

Structural Characterization of the Mammalian Deoxynucleotide N-Hydrolase Rcl and Its Stabilizing Interactions with Two Inhibitors
score: 4.9816005, Journal of Molecular Biology, 2009, Yang, Yinshan et. al.

Structural insight into the molecular basis of polyextremophilicity of short-chain alcohol dehydrogenase from the hyperthermophilic archaeon Thermococcus sibiricus
score: 4.9677105, Biochimie, 2012, Bezsudnova, Ekaterina Y. et. al.

Structural insight into the molecular basis of polyextremophilicity of short-chain alcohol dehydrogenase from the hyperthermophilic archaeon Thermococcus sibiricus
score: 4.9677105, Biochimie, 2012, Bezsudnova, Ekaterina Y. et. al.

Spacing between core recognition motifs determines relative orientation of AraR monomers on bipartite operators
score: 4.9629182, Nucleic Acids Research, 2012, Jain, Deepti; Nair, Deepak T.

A Dodecameric CcmK2 Structure Suggests β-Carboxysomal Shell Facets Have a Double-Layered Organization
score: 4.9603493, Structure, 2012, Samborska, Bożena; Kimber, Matthew S.

Crystal Structure of the MACPF Domain of Human Complement Protein C8α in Complex with the C8γ Subunit
score: 4.956338, Journal of Molecular Biology, 2008, Slade, Daniel J. et. al.

Crystal Structure of Mouse MD-1 with Endogenous Phospholipid Bound in Its Cavity
score: 4.953585, Journal of Molecular Biology, 2010, Harada, Hitomi; Ohto, Umeharu; Satow, Yoshinori

Chemical Inhibitors of Cyclin-Dependent Kinases
score: 4.9515155, Pharmacology and Therapeutics, 1999, Noble, Martin E.M; Endicott, Jane A

The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif
score: 4.9484067, Journal of Structural Biology, 2012, Carlier, Ludovic et. al.

The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif
score: 4.9484067, Journal of Structural Biology, 2012, Carlier, Ludovic et. al.

Structural Basis for 5′-End-Specific Recognition of Single-Stranded DNA by the R3H Domain from Human Sμbp-2
score: 4.9469715, Journal of Molecular Biology, 2012, Jaudzems, Kristaps et. al.

Structure-guided Discovery of Phenyl diketo-acids as Potent Inhibitors of M. tuberculosis Malate Synthase
score: 4.9396599, Chemistry & Biology, 2012, Krieger, Inna V. et. al.

Crystal structure of human natural cytotoxicity receptor NKp30 and identification of its ligand binding site.
score: 4.9371173, Proceedings of the National Academy of Sciences of the United States of America, 2011, Joyce, M Gordon et. al.

More than a Simple Lipophilic Contact: A Detailed Thermodynamic Analysis of Nonbasic Residues in the S1 Pocket of Thrombin
score: 4.932596, Journal of Molecular Biology, 2009, Baum, Bernhard et. al.

Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms
score: 4.9321684, Nucleic Acids Research, 2007, Tsunoda, Masaru et. al.

A dodecameric CcmK2 structure suggests β-carboxysomal shell facets have a double-layered organization
score: 4.9317099, Structure, 2012, Samborska, Bożena; Kimber, Matthew S.

Crystal structure of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis.
score: 4.9285395, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Shan, Shan et. al.

Apo structure of the ligand-binding domain of aspartate receptor from Escherichia coli and its comparison with ligand-bound or pseudoligand-bound structures
score: 4.9268224, FEBS Letters, 1997, Chi, Young-In; Yokota, Hisao; Kim, Sung-Hou

Structural Rearrangement Accompanying Ligand Binding in the GAF Domain of CodY from Bacillus subtilis
score: 4.9226024, Journal of Molecular Biology, 2009, Levdikov, Vladimir M. et. al.

A Structural Insight into the Molecular Recognition of a (−)-Δ 9-Tetrahydrocannabinol and the Development of a Sensitive, One-Step, Homogeneous Immunocomplex-Based Assay for Its Detection
score: 4.9162449, Journal of Molecular Biology, 2010, Niemi, Merja H. et. al.

Structural Basis for 5′-End-Specific Recognition of Single-Stranded DNA by the R3H Domain from Human Sμbp-2
score: 4.9160958, Journal of Molecular Biology, 2012, Jaudzems, Kristaps et. al.

Structural Basis for 5′-End-Specific Recognition of Single-Stranded DNA by the R3H Domain from Human Sμbp-2
score: 4.9160958, Journal of Molecular Biology, 2012, Jaudzems, Kristaps et. al.

Amino acid sequence and three-dimensional structure of the Tn-specific isolectin B4 from Vicia villosa
score: 4.9077651, FEBS Letters, 1997, Osinaga, Eduardo et. al.

Amino acid sequence and three-dimensional structure of the Tn-specific isolectin B4 from Vicia villosa
score: 4.9077651, FEBS Letters, 1997, Osinaga, Eduardo et. al.

Structure and Catalytic Mechanism of a Cyclic Dipeptide Prenyltransferase with Broad Substrate Promiscuity
score: 4.9077308, Journal of Molecular Biology, 2012, Schuller, Jan Michael et. al.

Solution structure of an atypical PHD finger in BRPF2 and its interaction with DNA
score: 4.9040882, Journal of Structural Biology, 2012, Liu, Lei et. al.

Solution structure of an atypical PHD finger in BRPF2 and its interaction with DNA
score: 4.9040882, Journal of Structural Biology, 2012, Liu, Lei et. al.

Interpreting a Low Resolution Map of Human U1 snRNP Using Anomalous Scatterers
score: 4.9032272, Structure (London, England : 1993), 2009, Oubridge, Chris et. al.

The Crystal Structure of the Intact E. coli RelBE Toxin-Antitoxin Complex Provides the Structural Basis for Conditional Cooperativity
score: 4.9017293, Structure, 2012, Bøggild, Andreas et. al.

The Crystal Structure of the Intact E. coli RelBE Toxin-Antitoxin Complex Provides the Structural Basis for Conditional Cooperativity
score: 4.9017293, Structure, 2012, Bøggild, Andreas et. al.

Crystal Structures of Complexes of the Branched-Chain Aminotransferase from Deinococcus radiodurans with α-Ketoisocaproate and L-Glutamate Suggest the Radiation Resistance of This Enzyme for Catalysis.
score: 4.8940832, Journal of bacteriology, 2012, Chen, Chung-De et. al.

The Crystal Structure of a Coxsackievirus B3-RD Variant and a Refined 9-Angstrom Cryo-Electron Microscopy Reconstruction of the Virus Complexed with Decay-Accelerating Factor (DAF) Provide a New Footprint of DAF on the Virus Surface.
score: 4.8844424, Journal of virology, 2012, Yoder, Joshua D et. al.

Structural basis of pre-mRNA recognition by the human cleavage factor Im complex.
score: 4.8780042, Cell research, 2011, Li, Heng et. al.

Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis.
score: 4.8734736, Protein science : a publication of the Protein Society, 2009, Lei, Jian; Zhou, Yan-Feng; Li, Lan-Fen; Su, Xiao-Dong

Active site topology and reaction mechanism of GTP cyclohydrolase I.
score: 4.8695152, Proceedings of the National Academy of Sciences of the United States of America, 1995, Nar, H et. al.

New insight into the dynamic properties and the active site architecture of H-Ras p21 revealed by X-ray crystallography at very high resolution
score: 4.8635329, BMC Structural Biology, 2010, Klink, Björn U; Scheidig, Axel J

Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5
score: 4.8618709, Archives of Biochemistry and Biophysics, 2009, Li, Xiaojun et. al.

Structural characterization of aD-isomer specific 2-hydroxyacid dehydrogenase fromLactobacillus delbrueckiissp.bulgaricus
score: 4.8616001, Journal of Structural Biology, 2013, Holton, Simon J. et. al.

Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation
score: 4.8603957, Nucleic Acids Research, 2012, Hashimoto, Hideharu et. al.

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity
score: 4.8571072, Cell, 1997, Yaffe, Michael B et. al.

Identification and structural basis for a novel interaction between Vav2 and Arap3
score: 4.8505379, Journal of Structural Biology, 2012, Wu, Bo et. al.

Identification and structural basis for a novel interaction between Vav2 and Arap3
score: 4.8505379, Journal of Structural Biology, 2012, Wu, Bo et. al.

Effect of coenzyme modification on the structural and catalytic properties of wild-type transketolase and of the variant E418A from Saccharomyces cerevisiae.
score: 4.8487811, The FEBS journal, 2005, Golbik, Ralph et. al.

Solution structure of Escherichia coli FeoA and its potential role in bacterial ferrous iron transport.
score: 4.8486312, Journal of bacteriology, 2012, Lau, Cheryl K Y et. al.

The crystal structure of ribosomal protein S4 reveals a two-domain molecule with an extensive RNA-binding surface: one domain shows structural homology to the ETS DNA-binding motif.
score: 4.8405962, The EMBO journal, 1998, Davies, C et. al.

Structural insights into Helicobacter pylori oncoprotein CagA interaction with β1 integrin.
score: 4.8385654, Proceedings of the National Academy of Sciences of the United States of America, 2012, Kaplan-Türköz, Burcu et. al.

Crystal structure of acidic seminal fluid protein (aSFP) at 1.9 Å resolution: a bovine polypeptide of the spermadhesin family 1 1 Edited by R. Huber
score: 4.8355256, Journal of Molecular Biology, 1997, Romão, Maria J et. al.

A glutamate switch controls voltage-sensitive phosphatase function.
score: 4.8351828, Nature structural & molecular biology, 2012, Liu, Lijun et. al.

Crystallographically mapped ligand binding differs in high and low IgE binding isoforms of birch pollen allergen Bet v 1
score: 4.8270687, Journal of Molecular Biology, 2012, Kofler, Stefan et. al.

Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails
score: 4.8266356, BMC Structural Biology, 2007, Huang, Hongda et. al.

Crystal Structure of the E. coli Hsp100 ClpB N-Terminal Domain
score: 4.8263483, Structure, 2003, Li, Jingzhi; Sha, Bingdong

Crystallographic study at 2·5 Å resolution of the interaction of methionyl-tRNA synthetase from Escherichia coli with ATP
score: 4.8197429, Journal of Molecular Biology, 1990, Brunie, S.; Zelwer, C.; Risler, J.-L.

X-ray structure determination and comparison of two crystal forms of a variant (Asn115Arg) of the alkaline protease from Bacillus alcalophilus refined at 1.85 Å resolution
score: 4.8177936, Journal of Molecular Biology, 1992, Sobek, H.; Hecht, H.-J.; Aehle, W.; Schomburg, D.

High resolution crystallographic studies of alpha-hemolysin-phospholipid complexes define heptamer-lipid head group interactions: implication for understanding protein-lipid interactions.
score: 4.8176875, Protein science : a publication of the Protein Society, 2004, Galdiero, Stefania; Gouaux, Eric

Structural Analysis of the Substrate Recognition Mechanism in O-phosphoserine Sulfhydrylase from the Hyperthermophilic Archaeon Aeropyrum pernix K1
score: 4.8172485, Journal of Molecular Biology, 2012, Nakamura, Takashi et. al.

Crystal structure of leukotriene A 4 hydrolase in complex with kelatorphan, implications for design of zinc metallopeptidase inhibitors
score: 4.8132062, FEBS Letters, 2010, Tholander, Fredrik et. al.

Crystal structure of leukotriene A 4 hydrolase in complex with kelatorphan, implications for design of zinc metallopeptidase inhibitors
score: 4.8132062, FEBS Letters, 2010, Tholander, Fredrik et. al.

Crystal structure of leukotriene A 4 hydrolase in complex with kelatorphan, implications for design of zinc metallopeptidase inhibitors
score: 4.8132062, FEBS Letters, 2010, Tholander, Fredrik et. al.

Crystal structure of an aldehyde reductase Y50F mutant-NADP complex and its implications for substrate binding.
score: 4.8130575, Proteins, 2001, Ye, Q et. al.

Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF.
score: 4.8051504, Protein science : a publication of the Protein Society, 2011, Chen, Zhe; Guo, Liang; Sprang, Stephen R; Sternweis, Paul C

Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface
score: 4.8035484, Cell Reports, 2012, Chartron, Justin W. et. al.

Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface
score: 4.8035484, Cell Reports, 2012, Chartron, Justin W. et. al.

The role of structural information in the discovery of direct thrombin and factor Xa inhibitors
score: 4.7994994, Trends in Pharmacological Sciences, 2012, Nar, Herbert

ATRX links atypical histone methylation recognition mechanisms to human brain function
score: 4.7966486, Nature structural & molecular biology, 2011, Iwase, Shigeki et. al.

Thermodynamic effects of proline introduction on protein stability.
score: 4.7931288, Proteins, 2007, Prajapati, Ravindra Singh et. al.

Structure of the St. Louis encephalitis virus postfusion envelope trimer.
score: 4.7832623, Journal of virology, 2012, Luca, Vincent C; Nelson, Christopher A; Fremont, Daved H

The crystal structure of the Mycobacterium tuberculosis Rv3019c-Rv3020c ESX complex reveals a domain-swapped heterotetramer.
score: 4.7811531, Protein science : a publication of the Protein Society, 2010, Arbing, Mark A et. al.

Effect of zinc on human IgG1 and its FcγR interactions
score: 4.7761986, Immunology Letters, 2012, Sibéril, Sophie et. al.

Crystal Structure of the Filamin N-Terminal Region Reveals a Hinge between the Actin Binding and First Repeat Domains
score: 4.771001, Journal of Molecular Biology, 2012, Sawyer, Gregory M.; Sutherland-Smith, Andrew J.

Crystal Structure of the Filamin N-Terminal Region Reveals a Hinge between the Actin Binding and First Repeat Domains
score: 4.771001, Journal of Molecular Biology, 2012, Sawyer, Gregory M.; Sutherland-Smith, Andrew J.

Molecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM Domain
score: 4.7703201, Journal of Molecular Biology, 2010, Hom, Robert A. et. al.

Variable Dimerization of the Ly49A Natural Killer Cell Receptor Results in Differential Engagement of its MHC Class I Ligand
score: 4.7684938, Journal of Molecular Biology, 2006, Dam, Julie et. al.

Structure of human POFUT2: insights into thrombospondin type 1 repeat fold and O-fucosylation.
score: 4.7668366, The EMBO journal, 2012, Chen, Chun-I et. al.

Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING
score: 4.7658155, Molecular Cell, 2012, Yin, Qian et. al.

Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING
score: 4.7658155, Molecular Cell, 2012, Yin, Qian et. al.

Crystal Structure of the Filamin N-Terminal Region Reveals a Hinge between the Actin Binding and First Repeat Domains
score: 4.7616583, Journal of Molecular Biology, 2012, Sawyer, Gregory M.; Sutherland-Smith, Andrew J.

Crystal structure of 2-hydroxyl-6-oxo-6-phenylhexa-2,4-dienoic acid (HPDA) hydrolase (BphD enzyme) from the Rhodococcus sp. strain RHA1 of the PCB degradation pathway 1 1 Edited by R. Huber
score: 4.7607195, Journal of Molecular Biology, 2001, Nandhagopal, Narayanasamy et. al.

Structures of Perfringolysin O Suggest a Pathway for Activation of Cholesterol-dependent Cytolysins
score: 4.7570855, Journal of Molecular Biology, 2007, Rossjohn, Jamie et. al.

Characterization of NADP + binding to perdeuterated MurB: backbone atom NMR assignments and chemical-shift changes 1 1 Edited by P. E. Wright
score: 4.7562516, Journal of Molecular Biology, 1997, Constantine, Keith L et. al.

Probing the Role of Aromatic Residues at the Secondary Saccharide-Binding Sites of Human Salivary α-Amylase in Substrate Hydrolysis and Bacterial Binding
score: 4.7507686, Journal of Molecular Biology, 2008, Ragunath, Chandran et. al.

Crystal and NMR structures of a Trp-cage mini-protein benchmark for computational fold prediction.
score: 4.7434403, Proceedings of the National Academy of Sciences of the United States of America, 2012, Scian, Michele et. al.

Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING
score: 4.742451, Molecular Cell, 2012, Yin, Qian et. al.

The crystal structure of galactitol-1-phosphate 5-dehydrogenase from Escherichia coli K12 provides insights into its anomalous behavior on IMAC processes
score: 4.740971, FEBS Letters, 2012, Esteban-Torres, María et. al.

Structural Basis of Transcriptional Pausing in Bacteria
score: 4.7382345, Cell, 2013, Weixlbaumer, Albert et. al.

The Structural and Biochemical Characterization of Human RNase H2 Complex Reveals the Molecular Basis for Substrate Recognition and Aicardi-Goutières Syndrome Defects *
score: 4.7379372, The Journal of Biological Chemistry, 2010, Figiel, Małgorzata et. al.

Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism.
score: 4.7373141, Proceedings of the National Academy of Sciences of the United States of America, 2012, Huang, Chia-Ying et. al.

Crystallographic structure of a peptidyl keto acid inhibitor and human α-thrombin
score: 4.7370174, Bioorganic & Medicinal Chemistry, 1995, Håkansson, Kjell et. al.

Side-chain Dynamics of the SAP SH2 Domain Correlate with a Binding Hot Spot and a Region with Conformational Plasticity
score: 4.7354544, Journal of Molecular Biology, 2002, Finerty, Patrick J; Muhandiram, Ranjith; Forman-Kay, Julie D

Binding Mechanism of Metal⋅NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases
score: 4.7346198, Structure, 2012, Rymer, Richard U. et. al.

Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å Resolution
score: 4.7337076, Cell, 1999, Zhang, Gongyi et. al.

Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification
score: 4.7287483, Nucleic Acids Research, 2007, Tsai, Kuang-Lei et. al.

NMR Structure of the SARS-CoV Nonstructural Protein 7 in Solution at pH 6.5
score: 4.723168, Journal of Molecular Biology, 2010, Johnson, Margaret A.; Jaudzems, Kristaps; Wüthrich, Kurt

Crystal structure and function of C-terminal Sau3AI domain
score: 4.7193863, BBA - Proteins and Proteomics, 2009, Xu, Chun-Yan et. al.

Structural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-Joining
score: 4.712329, Cell Reports, 2012, De Ioannes, Pablo et. al.

Structural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-Joining
score: 4.712329, Cell Reports, 2012, De Ioannes, Pablo et. al.

The 1.8 Å crystal structure of winged bean albumin 1, the major albumin from Psophocarpus tetragonolobus (L.) DC 1 1 Edited by K. Nagai
score: 4.7103241, Journal of Molecular Biology, 1997, McCoy, Airlie J; Kortt, Alexander A

The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes
score: 4.7084961, BBA - Molecular and Cell Biology of Lipids, 2012, Rengachari, Srinivasan et. al.

Specific Inhibition of Caspase-3 by a Competitive DARPin: Molecular Mimicry between Native and Designed Inhibitors
score: 4.7072436, Structure, 2013, Schroeder, Thilo et. al.

Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II
score: 4.7068181, Bioorganic & Medicinal Chemistry Letters, 2005, Fiore, Anna Di et. al.

Structural Basis of PP2A Inhibition by Small t Antigen
score: 4.7015872, PLoS Biology, 2007, Cho, Uhn Soo et. al.

Acetazolamide-based fungal chitinase inhibitors
score: 4.7014468, Bioorganic & Medicinal Chemistry, 2010, Schüttelkopf, Alexander W. et. al.

A 9 Å Resolution X-Ray Crystallographic Map of the Large Ribosomal Subunit
score: 4.6957435, Cell, 1998, Ban, Nenad et. al.

Characterization of Transport Proteins for Aromatic Compounds Derived from Lignin: Benzoate Derivative Binding Proteins
score: 4.6937693, Journal of Molecular Biology, 2012, Michalska, Karolina et. al.

Characterization of Transport Proteins for Aromatic Compounds Derived from Lignin: Benzoate Derivative Binding Proteins
score: 4.6937693, Journal of Molecular Biology, 2012, Michalska, Karolina et. al.

Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection
score: 4.6934632, Cell, 2012, Pos, Wouter et. al.

Structure and functionality in flavivirus NS-proteins: Perspectives for drug design
score: 4.6897506, Antiviral Research, 2010, Bollati, Michela et. al.

Structural and catalytic roles of amino acid residues located at substrate-binding pocket in Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase.
score: 4.6878539, Proteins, 2010, Chen, Je-Hsin et. al.

Structural Basis of Substrate Specificity and Selectivity of Murine Cytosolic 5′-Nucleotidase III
score: 4.653082, Journal of Molecular Biology, 2012, Grobosky, Christina L. et. al.

Structural Basis of Substrate Specificity and Selectivity of Murine Cytosolic 5′-Nucleotidase III
score: 4.653082, Journal of Molecular Biology, 2012, Grobosky, Christina L. et. al.

Functional Dissection of a Trigger Enzyme: Mutations of the Bacillus subtilis Glutamate Dehydrogenase RocG That Affect Differentially Its Catalytic Activity and Regulatory Properties
score: 4.6530557, Journal of Molecular Biology, 2010, Gunka, Katrin et. al.

Heterogeneity and Inaccuracy in Protein Structures Solved by X-Ray Crystallography
score: 4.6530122, Structure, 2004, DePristo, Mark A; de Bakker, Paul I.W; Blundell, Tom L

Structure of human aspartyl aminopeptidase complexed with substrate analogue: insight into catalytic mechanism, substrate specificity and M18 peptidase family
score: 4.6526621, BMC Structural Biology, 2012, Chaikuad, Apirat et. al.

Three-dimensional solution structure of a unique S100 protein
score: 4.6514936, Biochemical and Biophysical Research Communications, 2005, Sivaraja, Vaithiyalingam et. al.

Crystal structure and mechanism of CO dehydrogenase, a molybdo iron-sulfur flavoprotein containing S-selanylcysteine.
score: 4.651384, Proceedings of the National Academy of Sciences of the United States of America, 1999, Dobbek, H; Gremer, L; Meyer, O; Huber, R

Crystal structure of the 30 s ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 s RNA 1 1 Edited by R. Huber
score: 4.6430952, Journal of Molecular Biology, 2002, Brodersen, Ditlev E. et. al.

Substrate Recognition Mechanism of Atypical Protein Kinase Cs Revealed by the Structure of PKCι in Complex with a Substrate Peptide from Par-3
score: 4.6373832, Structure, 2012, Wang, Chihao; Shang, Yuan; Yu, Jiang; Zhang, Mingjie

Active site of trypanothione reductase
score: 4.6290083, Journal of Molecular Biology, 1992, Hunter, William N. et. al.

Structure and multiple conformations of the Kunitz-type domain from human type VI collagen α3(VI) chain in solution
score: 4.6239074, Structure, 1996, Zweckstetter, Markus et. al.

The crystal structure of apo-FtsH reveals domain movements necessary for substrate unfolding and translocation.
score: 4.6218798, Proceedings of the National Academy of Sciences of the United States of America, 2009, Bieniossek, Christoph et. al.

Crystal structures of triosephosphate isomerase from methicillin resistant Staphylococcus aureus MRSA252 provide structural insights into novel modes of ligand binding and unique conformations of catalytic loop
score: 4.6180892, Biochimie, 2012, Mukherjee, Somnath et. al.

Crystal structures of triosephosphate isomerase from methicillin resistant Staphylococcus aureus MRSA252 provide structural insights into novel modes of ligand binding and unique conformations of catalytic loop
score: 4.6180892, Biochimie, 2012, Mukherjee, Somnath et. al.

Crystal Structure of Methyl Parathion Hydrolase from Pseudomonas sp. WBC-3
score: 4.6089326, Journal of Molecular Biology, 2005, Dong, Yan-Jie et. al.

Solution Structure of the Heterotrimeric Complex between the Interaction Domains of RFX5 and RFXAP from the RFX Gene Regulatory Complex
score: 4.6006371, Journal of Molecular Biology, 2010, Laird, Kholiswa M. et. al.

The cAMP Receptor-Like Protein CLP Is a Novel c-di-GMP Receptor Linking Cell–Cell Signaling to Virulence Gene Expression in Xanthomonas campestris
score: 4.595487, Journal of Molecular Biology, 2010, Chin, Ko-Hsin et. al.

A Rationally Designed Monomeric Variant of Anthranilate Phosphoribosyltransferase from Sulfolobus solfataricus is as Active as the Dimeric Wild-type Enzyme but Less Thermostable
score: 4.5950333, Journal of Molecular Biology, 2008, Schwab, Thomas et. al.

Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein: Fatty Acid Binding Revisited
score: 4.5929406, Biophysical Journal, 2012, Cai, Jun et. al.

Proteins
score: 4.5834579, Current Opinion in Structural Biology, 1994,

An Alternative Conformation of the T-Cell Receptor α Constant Region
score: 4.5821751, Journal of Molecular Biology, 2010, van Boxel, Gijs I. et. al.

The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes
score: 4.5785843, BBA - Molecular and Cell Biology of Lipids, 2012, Rengachari, Srinivasan et. al.

The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes
score: 4.5785843, BBA - Molecular and Cell Biology of Lipids, 2012, Rengachari, Srinivasan et. al.

The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes
score: 4.5785843, BBA - Molecular and Cell Biology of Lipids, 2012, Rengachari, Srinivasan et. al.

Structural Transformation of the Tandem Ubiquitin-Interacting Motifs in Ataxin-3 and Their Cooperative Interactions with Ubiquitin Chains
score: 4.5748142, PLoS ONE, 2010, Song, Ai-Xin et. al.

Histone Recognition by Human Malignant Brain Tumor Domains
score: 4.5703944, Journal of Molecular Biology, 2012, Nady, Nataliya et. al.

Histone Recognition by Human Malignant Brain Tumor Domains
score: 4.5703944, Journal of Molecular Biology, 2012, Nady, Nataliya et. al.

Crystallographic analysis of AcrB
score: 4.5644491, FEBS Letters, 2004, Pos, Klaas M et. al.

Structural and functional analysis of the flexible regions of the catalytic α-subunit of protein kinase CK2
score: 4.5612405, Journal of Structural Biology, 2012, Papinutto, Elena et. al.

A novel domain arrangement in a monomeric cyclodextrin-hydrolyzing enzyme from the hyperthermophile Pyrococcus furiosus
score: 4.5596964, BBA - Proteins and Proteomics, 2013, Park, Jong-Tae et. al.

Assembly of Protein Subunits within the Stromal Ridge of Photosystem I. Structural Changes between Unbound and Sequentially PS I-bound Polypeptides and Correlated Changes of the Magnetic Properties of the Terminal Iron Sulfur Clusters
score: 4.5561205, Journal of Molecular Biology, 2003, Antonkine, Mikhail L. et. al.

CING: an integrated residue-based structure validation program suite
score: 4.5558216, Journal of Biomolecular Nmr, 2012, Doreleijers, Jurgen F. et. al.

Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase.
score: 4.5520108, Molecular cancer therapeutics, 2012, Ahmad, Md Faiz et. al.

Crystal structure of the rice branching enzyme I (BEI) in complex with maltopentaose
score: 4.5507084, Biochemical and Biophysical Research Communications, 2012, Chaen, Kimiko et. al.

Crystal Structure of Dimeric Flavodoxin from Desulfovibrio gigas Suggests a Potential Binding Region for the Electron-Transferring Partner
score: 4.5498443, International Journal of Molecular Sciences, 2013, Hsieh, Yin-Cheng et. al.

A novel approach to identifying β-secretase inhibitors: Bis-statine peptide mimetics discovered using structure and spot synthesis
score: 4.5477802, Peptides, 2006, Bridges, Kristie Grove et. al.

Structural Basis for the Dual Recognition of IL-12 and IL-23 by Ustekinumab
score: 4.5419277, Journal of Molecular Biology, 2010, Luo, Jinquan et. al.

Insights into nonspecific binding of homeodomains from a structure of MATalpha2 bound to DNA.
score: 4.5388756, Proteins, 2003, Aishima, Jun; Wolberger, Cynthia

Crystal Structures of Penicillin-Binding Protein 3 (PBP3) from Methicillin-Resistant Staphylococcus aureus in the Apo and Cefotaxime‐Bound Forms
score: 4.5334696, Journal of Molecular Biology, 2012, Yoshida, Hisashi et. al.

Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation
score: 4.5321372, The Journal of Biological Chemistry, 2012, Liu, Jinsong et. al.

Crystal Structure of Spy0129, a Streptococcus pyogenes Class B Sortase Involved in Pilus Assembly
score: 4.5239908, PLoS ONE, 2011, Kang, Hae Joo et. al.

Allosteric Activation Mechanism of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknB
score: 4.5224216, Structure, 2010, Lombana, T. Noelle et. al.

Structural basis for engagement by complement factor H of C3b on a self surface
score: 4.521893, Nature structural & molecular biology, 2011, Morgan, Hugh P. et. al.

Structure and stability of a thermostable carboxylesterase from the thermoacidophilic archaeon Sulfolobus tokodaii.
score: 4.5148736, The FEBS journal, 2012, Angkawidjaja, Clement et. al.

Folate binding site of flavin-dependent thymidylate synthase.
score: 4.5130829, Proceedings of the National Academy of Sciences of the United States of America, 2012, Koehn, Eric M et. al.

The crystal structure of a lysozyme c from housefly Musca domestica, the first structure of a digestive lysozyme
score: 4.5081116, Journal of Structural Biology, 2007, Cançado, Fabiane Chaves et. al.

Solution structure and dynamics of the single-chain hepatitis C virus NS3 protease NS4A cofactor complex 1 1 Edited by M. F. Summers
score: 4.5066739, Journal of Molecular Biology, 2001, McCoy, Mark A et. al.

The Binding of Antibiotics in OmpF Porin
score: 4.5055785, Structure, 2013, Ziervogel, Brigitte K.; Roux, Benoît

Rational mutagenesis to support structure-based drug design: MAPKAP kinase 2 as a case study
score: 4.5055316, BMC Structural Biology, 2009, Argiriadi, Maria A et. al.

Evaluating protein structures determined by structural genomics consortia.
score: 4.5001988, Proteins, 2007, Bhattacharya, Aneerban et. al.

Structural Model of the R State of Escherichia coli Aspartate Transcarbamoylase with Substrates Bound
score: 4.4964914, Journal of Molecular Biology, 2007, Wang, Jie; Eldo, Joby; Kantrowitz, Evan R.

Atomic structure of a CK2alpha human kinase by microfocus diffraction of extra-small microcrystals grown with nanobiofilm template.
score: 4.4909356, Journal of cellular biochemistry, 2004, Pechkova, Eugenia; Nicolini, Claudio

Protein engineering
score: 4.4885444, Current Opinion in Biotechnology, 1993,

The Hexameric Structures of Human Heat Shock Protein 90
score: 4.4837398, PLoS ONE, 2011, Lee, Cheng-Chung et. al.

Structural and Functional Aspects of the Sensor Histidine Kinase PrrB from Mycobacterium tuberculosis
score: 4.4748517, Structure, 2006, Nowak, Elzbieta et. al.

Solution structure of the c-terminal core domain of human TFIIB: Similarity to cyclin A and interaction with TATA-binding protein
score: 4.4734029, Cell, 1995, Bagby, Stefan et. al.

IRAK-4 Inhibitors for Inflammation
score: 4.4687781, Current Topics in Medicinal Chemistry, 2009, Wang, Zhulun et. al.

Substrate recognition by family 7 alginate lyase from Sphingomonas sp. A1
score: 4.4685642, Journal of Molecular Biology, 2008, Ogura, Kohei et. al.

Structure and dynamics of MarA-DNA complexes: an NMR investigation 1 1 Edited by M. F. Summers
score: 4.4662591, Journal of Molecular Biology, 2001, Dangi, Bindi et. al.

GeNMR: a web server for rapid NMR-based protein structure determination
score: 4.4656168, Nucleic Acids Research, 2009, Berjanskii, Mark et. al.

Crystal Structure of 12-Lipoxygenase Catalytic-Domain-Inhibitor Complex Identifies a Substrate-Binding Channel for Catalysis
score: 4.4628573, Structure, 2012, Xu, Shu et. al.

The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif
score: 4.4594583, Nucleic Acids Research, 2012, Ohlenschläger, Oliver et. al.

Crystal structure of the catalytic domain of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase at a resolution of 1.8 Å
score: 4.4575307, Virology, 2008, Yamashita, Tetsuo et. al.

Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity.
score: 4.4491927, The EMBO journal, 2008, Rumpf, Julia et. al.

Acetazolamide-based fungal chitinase inhibitors
score: 4.447179, Bioorganic & Medicinal Chemistry, 2010, Schüttelkopf, Alexander W. et. al.

Promoter-Specific Transcription Inhibition in Staphylococcus aureus by a Phage Protein
score: 4.4403386, Cell, 2012, Osmundson, Joseph et. al.

Comparison of the decameric structure of peroxiredoxin-II by transmission electron microscopy and X-ray crystallography
score: 4.4398234, Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology, 2001, Harris, J.Robin et. al.

The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1
score: 4.4348627, Nucleic Acids Research, 2012, Bazzicalupi, Carla et. al.

Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
score: 4.4319106, Proceedings of the National Academy of Sciences of the United States of America, 2012, Kato, Kazuki et. al.

Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: purification, crystallization and structure determination 1 1 Edited by T. Richmond
score: 4.4306552, Journal of Molecular Biology, 2001, Clemons, William M. et. al.

Crystal Structure of the Human Ecto-5′-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling
score: 4.4305293, Structure, 2012, Knapp, Karen et. al.

Crystal Structure of the Human Ecto-5′-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling
score: 4.4305293, Structure, 2012, Knapp, Karen et. al.

Structural basis of p38α regulation by hematopoietic tyrosine phosphatase.
score: 4.4297585, Nature chemical biology, 2011, Francis, Dana M et. al.

Crystal structure of RlmM, the 2′O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA
score: 4.4283134, Nucleic Acids Research, 2012, Punekar, Avinash S. et. al.

First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: Discovery of an extra-pocket in the catalytic domain responsible for its endo-activity
score: 4.4175198, Biochimie, 2012, Pouyez, Jenny et. al.

First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: Discovery of an extra-pocket in the catalytic domain responsible for its endo-activity
score: 4.4175198, Biochimie, 2012, Pouyez, Jenny et. al.

Charges, hydrogen bonds, and correlated motions in the 1 å resolution refined structure of the mating pheromone E r-1 from Euplotes raikovi 1 1 Edited by D. Rees
score: 4.4142425, Journal of Molecular Biology, 1997, Anderson, Daniel H.; Weiss, Manfred S.; Eisenberg, David

The crystal structure of an activatedThermotoga maritimaCheY with N-terminal region of FliM
score: 4.4069933, International Journal of Biological Macromolecules, 2013, Ahn, Dae-Ro et. al.

The crystal structure of an activatedThermotoga maritimaCheY with N-terminal region of FliM
score: 4.4069933, International Journal of Biological Macromolecules, 2013, Ahn, Dae-Ro et. al.

Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex
score: 4.4068951, Nucleic Acids Research, 2009, Ortega-Roldan, Jose Luis et. al.

Chemical and StructuralAnalysis of an Antibody FoldingIntermediate Trapped during Glycan Biosynthesis
score: 4.4066254, Journal of the American Chemical Society, 2012, Bowden, Thomas A. et. al.

Crystal structures of the Arabidopsis thaliana abscisic acid receptor PYL10 and its complex with abscisic acid
score: 4.4059232, Biochemical and Biophysical Research Communications, 2012, Sun, Demeng et. al.

Insights into substrate recognition by the Escherichia coli Orf135 protein through its solution structure
score: 4.3999061, Biochemical and Biophysical Research Communications, 2012, Kawasaki, Kumiko et. al.

Structure of Lumazine Protein, an Optical Transponder of Luminescent Bacteria
score: 4.3963974, Journal of Molecular Biology, 2008, Chatwell, Lorenz et. al.

Probing Structural Determinants Distal to the Site of Hydrolysis that Control Substrate Specificity of the 20S Proteasome
score: 4.3932097, Chemistry & Biology, 2002, Groll, Michael; Nazif, Tamim; Huber, Robert; Bogyo, Matthew

Structure-Guided Discovery of Phenyl-diketo Acids as Potent Inhibitors of M. tuberculosis Malate Synthase
score: 4.3920347, Chemistry & Biology, 2012, Krieger, Inna V. et. al.

Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody.
score: 4.3915867, Journal of virology, 2012, Potter, Jane A et. al.

Solution structure of the extraterminal domain of the bromodomain-containing protein BRD4.
score: 4.3912717, Protein science : a publication of the Protein Society, 2008, Lin, Yi-Jan et. al.

Solution structures of yeast Saccharomyces cerevisiae calmodulin in calcium- and target peptide-bound states reveal similarities and differences to vertebrate calmodulin.
score: 4.3866025, Genes to cells : devoted to molecular & cellular mechanisms, 2012, Ogura, Kenji et. al.

Structural Basis of the Transition-state Stabilization in Antibody-catalyzed Hydrolysis
score: 4.3858564, Journal of Molecular Biology, 2007, Sakakura, Masayoshi et. al.

Structure-function analysis of human l-prostaglandin D synthase bound with fatty acid molecules.
score: 4.3853571, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Zhou, Yangyan et. al.

Crystal structures of Nipah and Hendra virus fusion core proteins.
score: 4.3852802, The FEBS journal, 2006, Lou, Zhiyong et. al.

Hydration in proteins observed by high-resolution neutron crystallography.
score: 4.3845973, Proteins, 2003, Chatake, Toshiyuki et. al.

Crystal structure of a fungal protease inhibitor from Antheraea mylitta
score: 4.3832134, Journal of Structural Biology, 2009, Roy, Sobhan et. al.

Crystallographically Mapped Ligand Binding Differs in High and Low IgE Binding Isoforms of Birch Pollen Allergen Bet v 1
score: 4.3818564, Journal of Molecular Biology, 2012, Kofler, Stefan et. al.

Crystallographically Mapped Ligand Binding Differs in High and Low IgE Binding Isoforms of Birch Pollen Allergen Bet v 1
score: 4.3818564, Journal of Molecular Biology, 2012, Kofler, Stefan et. al.

Solution Structure of S100A1 Bound to the CapZ Peptide (TRTK12)
score: 4.3766978, Journal of Molecular Biology, 2009, Wright, Nathan T. et. al.

Structural Reorganization Triggered by Charging of Lys Residues in the Hydrophobic Interior of a Protein
score: 4.373901, Structure, 2012, Chimenti, Michael S. et. al.

Structural Reorganization Triggered by Charging of Lys Residues in the Hydrophobic Interior of a Protein
score: 4.373901, Structure, 2012, Chimenti, Michael S. et. al.

Crystal structure of a lactosucrose-producing enzyme, Arthrobacter sp. K-1 β-fructofuranosidase
score: 4.3699196, Enzyme and Microbial Technology, 2012, Tonozuka, Takashi et. al.

Crystal structure of a lactosucrose-producing enzyme, Arthrobacter sp. K-1 β-fructofuranosidase
score: 4.3699196, Enzyme and Microbial Technology, 2012, Tonozuka, Takashi et. al.

New protein fold revealed by a 1.65 A resolution crystal structure of Francisella tularensis pathogenicity island protein IglC.
score: 4.3656428, Protein science : a publication of the Protein Society, 2007, Sun, Ping et. al.

The crystal and molecular structure of a collagen-like peptide with A biologically relevant sequence 1 2 Edited by I. A. Wilson
score: 4.3630086, Journal of Molecular Biology, 2001, Kramer, Rachel Z et. al.

Structure of the surface layer of the methanogenic archaean Methanosarcina acetivorans.
score: 4.3591914, Proceedings of the National Academy of Sciences of the United States of America, 2012, Arbing, Mark A et. al.

A structurally conserved water molecule in Rossmann dinucleotide-binding domains.
score: 4.357424, Protein science : a publication of the Protein Society, 2002, Bottoms, Christopher A; Smith, Paul E; Tanner, John J

Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design
score: 4.355059, Bioorganic & Medicinal Chemistry, 2006, Tsao, Désirée H.H. et. al.

Structures of cyanobactin maturation enzymes define a new family of transamidating proteases
score: 4.3545033, Chemistry & Biology, 2012, Agarwal, Vinayak et. al.

Entropically Driven MHC Class I Recognition by Human Inhibitory Receptor Leukocyte Ig-like Receptor B1 (LILRB1/ILT2/CD85j)
score: 4.3532587, Journal of Molecular Biology, 2006, Shiroishi, Mitsunori et. al.

Visualizing and quantifying molecular goodness-of-fit: small-probe contact dots with explicit hydrogen atoms 1 1 Edited by J. Thornton
score: 4.3465617, Journal of Molecular Biology, 1999, Word, J.Michael et. al.

The 1.6 Å Crystal Structure of Pyranose Dehydrogenase from Agaricus meleagris Rationalizes Substrate Specificity and Reveals a Flavin Intermediate
score: 4.3460683, PLoS ONE, 2013, Tan, Tien Chye et. al.

Structural and Functional Studies of the Phage Sf6 Terminase Small Subunit Reveal a DNA-Spooling Device Facilitated by Structural Plasticity
score: 4.345712, Journal of Molecular Biology, 2012, Zhao, Haiyan et. al.

Solution structure of the carboxyl terminus of a human class mu glutathione S-transferase: NMR assignment strategies in large proteins 1 1 Edited by P. E. Wright
score: 4.3432152, Journal of Molecular Biology, 1999, McCallum, Scott A; Hitchens, T.Kevin; Rule, Gordon S

Hidden alternate structures of proline isomerase essential for catalysis
score: 4.3431343, Nature, 2009, Fraser, James S. et. al.

Vancomycin Forms Ligand-Mediated Supramolecular Complexes
score: 4.3424926, Journal of Molecular Biology, 2009, Loll, Patrick J. et. al.

Improving the Accuracy of Macromolecular Structure Refinement at 7 Å Resolution
score: 4.3415902, Structure, 2012, Brunger, Axel T. et. al.

Kinase recognition by calmodulin: modeling the interaction with the autoinhibitory region of human cardiac titin kinase 1 1 Edited by J. Thornton
score: 4.3410708, Journal of Molecular Biology, 2001, Amodeo, Pietro et. al.

Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
score: 4.3376366, Journal of immunology (Baltimore, Md. : 1950), 2012, Zhang, Jianhua et. al.

Crystal structure of Bombyx mori nucleopolyhedrovirus ORF75 reveals a pseudo-dimer of thiol oxidase domains with a putative substrate-binding pocket.
score: 4.3375167, The Journal of general virology, 2012, Hou, Yong; Xia, Qingyou; Yuan, Y Adam

Hidden alternative structures of proline isomerase essential for catalysis.
score: 4.3362125, Nature, 2009, Fraser, James S et. al.

Crystal structure of JlpA, a surface-exposed lipoprotein adhesin of Campylobacter jejuni
score: 4.3359599, Journal of Structural Biology, 2012, Kawai, Fumihiro et. al.

Full-Length Structures of BenM and Two Variants Reveal Different Oligomerization Schemes for LysR-Type Transcriptional Regulators
score: 4.3357767, Journal of Molecular Biology, 2010, Ruangprasert, Ajchareeya et. al.

Crystal Structural and Functional Analysis of the Putative Dipeptidase from Pyrococcus horikoshii OT3
score: 4.3345036, Journal of Biophysics, 2009, Jeyakanthan, Jeyaraman et. al.

Dynamics and DNA Substrate Recognition by the Catalytic Domain of Lambda Integrase
score: 4.3328813, Journal of Molecular Biology, 2003, Subramaniam, Srisunder et. al.

Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1.
score: 4.3270131, The EMBO journal, 1997, Egloff, M P et. al.

High resolution crystal structures of free thrombin in the presence of K + reveal the molecular basis of monovalent cation selectivity and an inactive slow form
score: 4.326737, Biophysical Chemistry, 2006, Carrell, Christopher J. et. al.

Structure of GABARAP in Two Conformations
score: 4.3266766, Neuron, 2002, Coyle, Joseph E. et. al.

Biochemical characterization of two thymidylate synthases in Corynebacterium glutamicum NCHU 87078
score: 4.3231783, BBA - Proteins and Proteomics, 2010, Kan, Shu-Chen et. al.

A Novel Intein-Like Autoproteolytic Mechanism in Autotransporter Proteins
score: 4.3198691, Journal of Molecular Biology, 2010, Tajima, Nami et. al.

Structural basis of human pregnane X receptor activation by the hops constituent colupulone.
score: 4.3144598, Molecular pharmacology, 2008, Teotico, Denise G et. al.

Methods for X-ray diffraction analysis of macromolecular structures
score: 4.3123149, Current Opinion in Chemical Biology, 1999, Beauchamp, Jeremy C; Isaacs, Neil W

Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells
score: 4.3104125, Leukemia, 2012, Etchin, J et. al.

Crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 in complex with 8-iso prostaglandin A(1).
score: 4.309788, Proteins, 2011, Han, Byung Woo et. al.

Structure of theTrypanosoma cruziprotein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas’ disease
score: 4.3093129, Molecular & Biochemical Parasitology, 2013, Lountos, George T.; Tropea, Joseph E.; Waugh, David S.

Structure of the Trypanosoma cruzi protein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas’ disease
score: 4.3093129, Molecular & Biochemical Parasitology, 2013, Lountos, George T.; Tropea, Joseph E.; Waugh, David S.

Structural comparison of ColH and ColG collagen-binding domains from Clostridium histolyticum.
score: 4.3092378, Journal of bacteriology, 2012, Bauer, Ryan et. al.

Protein Structure Elucidation from Minimal NMR Data: The CLOUDS Approach
score: 4.3042127, Methods in Enzymology, 2005, Grishaev, Alexander; Llinás, Miguel

Protein Structure Elucidation from Minimal NMR Data: The CLOUDS Approach
score: 4.3042127, Methods in Enzymology, 2005, Grishaev, Alexander; Llinás, Miguel

Structure-function relationship in an archaebacterial methionine sulphoxide reductase B.
score: 4.3034677, Molecular microbiology, 2011, Carella, Michela et. al.

Structural Basis of Affinity Maturation and Intramolecular Cooperativity in a Protein-Protein Interaction
score: 4.3006199, Structure, 2005, Cho, Sangwoo et. al.

Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways
score: 4.2963133, Structure, 2012, Aragón, Eric et. al.

Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways
score: 4.2963133, Structure, 2012, Aragón, Eric et. al.

Crystal structure of the human ephrin-A5 ectodomain.
score: 4.2938482, Protein science : a publication of the Protein Society, 2007, Nikolov, Dimitar et. al.

Structural Insights into the Specific Binding of Huntingtin Proline-Rich Region with the SH3 and WW Domains
score: 4.2873386, Structure, 2006, Gao, Yong-Guang et. al.

Structural Basis for the Specific Recognition of Methylated Histone H3 Lysine 4 by the WD-40 Protein WDR5
score: 4.2771296, Molecular Cell, 2006, Han, Zhifu et. al.

Structure-based optimization of designed Armadillo-repeat proteins.
score: 4.2757921, Protein science : a publication of the Protein Society, 2012, Madhurantakam, Chaithanya et. al.

T Cell-Mediated Autoimmune Disease Due to Low-Affinity Crossreactivity to Common Microbial Peptides
score: 4.2723629, Immunity, 2009, Harkiolaki, Maria et. al.

Structure of the VirB4 ATPase, alone and bound to the core complex of a type IV secretion system.
score: 4.271842, Proceedings of the National Academy of Sciences of the United States of America, 2012, Walldén, Karin et. al.

Structural Insights into the Subclass B3 Metallo-β-Lactamase, SMB-1, and the Mode of Inhibition by the Common Metallo-β-Lactamase Inhibitor, Mercaptoacetate.
score: 4.2710347, Antimicrobial agents and chemotherapy, 2012, Wachino, Jun-Ichi et. al.

The NMR solution structure of the ubiquitin homology domain of Bcl-2-associated athanogene 1 (BAG-1-UBH) fromMus musculus
score: 4.2699672, Biochemical and Biophysical Research Communications, 2013, Huang, Hsiao-Wen; Yu, C.

Compact reduced thioredoxin structure from the thermophilic bacteria Thermus thermophilus.
score: 4.2699543, Proteins, 2005, Rehse, Peter H; Kumei, Maki; Tahirov, Tahir H

The Structure of Myristoylated Mason-Pfizer Monkey Virus Matrix Protein and the Role of Phosphatidylinositol-(4,5)-Bisphosphate in Its Membrane Binding
score: 4.2662906, Journal of Molecular Biology, 2012, Prchal, Jan et. al.

Structure of the ATP synthase catalytic complex (F(1)) from Escherichia coli in an autoinhibited conformation.
score: 4.2652497, Nature structural & molecular biology, 2011, Cingolani, Gino; Duncan, Thomas M

Specific protein dynamics near the solvent glass transition assayed by radiation-induced structural changes.
score: 4.2651283, Protein science : a publication of the Protein Society, 2001, Weik, M et. al.

Structural analysis of hepatitis C virus core-e1 signal Peptide and requirements for cleavage of the genotype 3a signal sequence by signal Peptide peptidase.
score: 4.2643075, Journal of virology, 2012, Oehler, Verena et. al.

The Crystal Structure of Carnitine Palmitoyltransferase 2 and Implications for Diabetes Treatment
score: 4.2636065, Structure, 2006, Rufer, Arne C. et. al.

Specific inhibition of Caspase-3 by a competitive DARPin: molecular mimicry between native and designed inhibitors
score: 4.2617984, Structure, 2013, Schroeder, Thilo et. al.

Thioredoxin as a fusion tag for carrier-driven crystallization.
score: 4.2574787, Protein science : a publication of the Protein Society, 2008, Corsini, Lorenzo et. al.

How to Avoid Premature Decay of Your Macromolecular Crystal: A Quick Soak for Long Life
score: 4.2535238, Structure, 2006, Kauffmann, Brice et. al.

Structural basis for site-specific ribose methylation by box C/D RNA protein complexes.
score: 4.2513537, Nature, 2011, Lin, Jinzhong et. al.

Crystal structure of non-redox regulated SSADH from Escherichia coli
score: 4.2472861, Biochemical and Biophysical Research Communications, 2010, Ahn, Jae-Woo; Kim, Yeon-Gil; Kim, Kyung-Jin

Additional Binding Sites for Anionic Phospholipids and Calcium Ions in the Crystal Structures of Complexes of the C2 Domain of Protein Kinase Cα
score: 4.2461655, Journal of Molecular Biology, 2002, Ochoa, Wendy F. et. al.

NMR solution structure of C2 domain of MFG-E8 and insights into its molecular recognition with phosphatidylserine
score: 4.244797, BBA - Biomembranes, 2013, Ye, Hong et. al.

Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel.
score: 4.2442048, Nature, 2009, Wang, Yi et. al.

Recommendations for the presentation of NMR structures of proteins and nucleic acids
score: 4.2435724, Journal of Molecular Biology, 1998, Markley, John L et. al.

Binding model of human coactosin-like protein with filament actin revealed by mutagenesis
score: 4.2414899, BBA - Proteins and Proteomics, 2006, Dai, Haiming et. al.

Nuclear magnetic resonance structure of calcium-binding protein 1 in a Ca(2+) -bound closed state: implications for target recognition.
score: 4.2413864, Protein science : a publication of the Protein Society, 2011, Park, Saebomi; Li, Congmin; Ames, James B

Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain
score: 4.2409191, mAbs, 2012, Schlatter, Daniel et. al.

The crystallographic structure of Panicum Mosaic Virus (PMV)
score: 4.2395607, Journal of Structural Biology, 2013, Makino, Debora L.; Larson, Steven B.; McPherson, Alexander

Solution characterization of [methyl- 13C]methionine HIV-1 reverse transcriptase by NMR spectroscopy
score: 4.2395038, Antiviral Research, 2009, Zheng, Xunhai et. al.

Autoproteolytic and Catalytic Mechanisms for the β-Aminopeptidase BapA—A Member of the Ntn Hydrolase Family
score: 4.2375489, Structure, 2012, Merz, Tobias et. al.

Autoproteolytic and Catalytic Mechanisms for the β-Aminopeptidase BapA—A Member of the Ntn Hydrolase Family
score: 4.2375489, Structure, 2012, Merz, Tobias et. al.

Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5
score: 4.2365324, Biochemical and Biophysical Research Communications, 2012, Zheng, Yingying et. al.

Crystal structure of bovine trypsin and wheat germ trypsin inhibitor (I-2b) complex (2:1) at 2.3 a resolution.
score: 4.2318746, Journal of biochemistry, 2002, Raj, S Shanmuga Sundara et. al.

Molecular Design, Functional Characterization and Structural Basis of a Protein Inhibitor Against the HIV-1 Pathogenicity Factor Nef
score: 4.2291978, PLoS ONE, 2011, Breuer, Sebastian et. al.

The multifunctional human p100 protein 'hooks' methylated ligands.
score: 4.2249312, Nature structural & molecular biology, 2007, Shaw, Neil et. al.

Structure of hyperthermophilic β-glucosidase from Pyrococcus furiosus
score: 4.2241035, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2011, Kado, Yuji; Inoue, Tsuyoshi; Ishikawa, Kazuhiko

Three-dimensional structure of poliovirus receptor bound to poliovirus.
score: 4.2235503, Proceedings of the National Academy of Sciences of the United States of America, 2000, Belnap, D M et. al.

Comparison of X-Ray Crystal Structure of the 30S Subunit-Antibiotic Complex with NMR Structure of Decoding Site Oligonucleotide-Paromomycin Complex
score: 4.2189387, Structure, 2003, Lynch, Stephen R; Gonzalez, Ruben L; Puglisi, Joseph D

Ligand-induced fit in mycobacterial MabA: the sequence-specific C-terminus locks the conformational change.
score: 4.218034, Proteins, 2005, Cohen-Gonsaud, Martin et. al.

Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau protein:Hypoxia Inducible Factor 1α Protein-Protein Interface
score: 4.2160657, Chemistry & Biology, 2012, Van Molle, Inge et. al.

Molecular Interplay between the Replicative Helicase DnaC and Its Loader Protein DnaI from Geobacillus kaustophilus
score: 4.2157676, Journal of Molecular Biology, 2009, Tsai, Kuang-Lei; Lo, Yu-Hua; Sun, Yuh-Ju; Hsiao, Chwan-Deng

Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element.
score: 4.2134282, Nature structural & molecular biology, 2012, Kim, In-Kwon et. al.

Structure of the outer membrane complex of a type IV secretion system
score: 4.2125813, Nature, 2009, Chandran, Vidya et. al.

The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor.
score: 4.2094041, Nucleic acids research, 2013, Hew, Kelly et. al.

Biochemical and structural characterization of a short-chain dehydrogenase/reductase of Thermus thermophilus HB8
score: 4.2091999, Chemico-Biological Interactions, 2009, Asada, Yukuhiko et. al.

An α Helix to β Barrel Domain Switch Transforms the Transcription Factor RfaH into a Translation Factor
score: 4.2091839, Cell, 2012, Burmann, Björn M. et. al.

Crystal structure of the C-terminal domain of Mu phage central spike and functions of bound calcium ion
score: 4.2091611, BBA - Proteins and Proteomics, 2013, Harada, Kenichi et. al.

Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis
score: 4.2047384, Journal of Structural Biology, 2012, Trivella, Daniela B.B. et. al.

Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis
score: 4.2047384, Journal of Structural Biology, 2012, Trivella, Daniela B.B. et. al.

NMR of hydrogen bonding in cold-shock protein A and an analysis of the influence of crystallographic resolution on comparisons of hydrogen bond lengths.
score: 4.2045838, Protein science : a publication of the Protein Society, 2001, Alexandrescu, A T; Snyder, D R; Abildgaard, F

Human DNA Polymerase κ Encircles DNA: Implications for Mismatch Extension and Lesion Bypass
score: 4.2032306, Molecular Cell, 2007, Lone, Samer et. al.

Solution structure of the DNA-binding domain of the heat shock transcription factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
score: 4.2004522, Protein science : a publication of the Protein Society, 1994, Damberger, F F et. al.

Crystal structure of curcuminoid synthase CUS from Oryza sativa.
score: 4.1984426, Proteins, 2011, Miyazono, Ken-ichi et. al.

Proteins
score: 4.1979907, Current Opinion in Structural Biology, 1996,

3,5-dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteria.
score: 4.1954064, Antimicrobial agents and chemotherapy, 2006, Yang, Youjun et. al.

Crystal structure of TTHA0061, an uncharacterized protein from Thermus thermophilus HB8, reveals a novel fold
score: 4.1952256, Biochemical and Biophysical Research Communications, 2010, Tanaka, Tomoyuki et. al.

The Crystal Structures of TrkA and TrkB Suggest Key Regions for Achieving Selective Inhibition
score: 4.1951882, Journal of Molecular Biology, 2012, Bertrand, T. et. al.

HIV‐1 Protease: Structure, Dynamics, and Inhibition
score: 4.1945584, Advances in Pharmacology, 2007, Louis, John M. et. al.

Conformational and dynamics simulation study of antimicrobial peptide hedistin—heterogeneity of its helix–turn–helix motif
score: 4.1936619, BBA - Biomembranes, 2009, Xu, Guohua et. al.

Calf spleen purine nucleoside phosphorylase: purification, sequence and crystal structure of its complex with an N(7)-acycloguanosine inhibitor
score: 4.1885168, FEBS Letters, 1995, Bzowska, Agnieszka et. al.

The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme
score: 4.1876184, Structure, 2012, O'Connell, Nichole et. al.

The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme
score: 4.1876184, Structure, 2012, O'Connell, Nichole et. al.

A Gate-Latch-Lock Mechanism for Hormone Signaling by Abscisic Acid Receptors
score: 4.183515, Nature, 2009, Melcher, Karsten et. al.

Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity
score: 4.1812356, Structure, 1996, Curry, Stephen et. al.

Determination of the Structure of the Catabolic N- Succinylornithine Transaminase (AstC) from Escherichia coli
score: 4.1810836, PLoS ONE, 2013, Newman, Janet et. al.

Atomic structure of the vimentin central α-helical domain and its implications for intermediate filament assembly.
score: 4.1791202, Proceedings of the National Academy of Sciences of the United States of America, 2012, Chernyatina, Anastasia A et. al.

Three-dimensional structure of a viral genome-delivery portal vertex.
score: 4.1787542, Nature structural & molecular biology, 2011, Olia, Adam S et. al.

Structural consequences of the familial amyotrophic lateral sclerosis SOD1 mutant His46Arg.
score: 4.1767076, Protein science : a publication of the Protein Society, 2005, Antonyuk, Svetlana et. al.

Structural comparison of two strains of foot-and-mouth disease virus subtype O 1 and a laboratory antigenic variant, G67
score: 4.176177, Structure, 1995, Lea, Susan et. al.

Four Distinct Structural Domains in Clostridium difficile Toxin B Visualized Using SAXS
score: 4.1748999, Journal of Molecular Biology, 2010, Albesa-Jové, David et. al.

A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.
score: 4.1745261, Nature, 2009, Melcher, Karsten et. al.

NMR in structural proteomics and beyond
score: 4.1718576, Progress in Nuclear Magnetic Resonance Spectroscopy, 2010, Banci, Lucia; Bertini, Ivano; Luchinat, Claudio; Mori, Mirko

Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets
score: 4.1711655, Nucleic Acids Research, 2010, Díaz-Moreno, Irene et. al.

RECOORD: a recalculated coordinate database of 500+ proteins from the PDB using restraints from the BioMagResBank.
score: 4.1705911, Proteins, 2005, Nederveen, Aart J et. al.

Crystal Structure of Diedel, a Marker of the Immune Response of Drosophila melanogaster
score: 4.1674265, PLoS ONE, 2012, Coste, Franck et. al.

The NMR solution structure of the ubiquitin homology domain of Bcl-2-associated athanogene 1 (BAG-1-UBH) fromMus musculus
score: 4.1661393, Biochemical and Biophysical Research Communications, 2013, Huang, Hsiao-Wen; Yu, C.

The NMR solution structure of the ubiquitin homology domain of Bcl-2-associated athanogene 1 (BAG-1-UBH) fromMus musculus
score: 4.1661393, Biochemical and Biophysical Research Communications, 2013, Huang, Hsiao-Wen; Yu, C.

High-resolution structures of AidH complexes provide insights into a novel catalytic mechanism for N -acyl homoserine lactonase
score: 4.1652198, Acta Crystallographica Section D: Biological Crystallography, 2012, Gao, Ang et. al.

Crystal structure of HutZ, a heme storage protein from Vibrio cholerae : A structural mismatch observed in the region of high sequence conservation
score: 4.1637425, BMC Structural Biology, 2012, Liu, Xiuhua et. al.

Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain
score: 4.1631429, Biochemical Journal, 2012, Park, Jin H. et. al.

Crystal structure of Onconase at 1.1 Å resolution--insights into substrate binding and collective motion.
score: 4.1628603, The FEBS journal, 2011, Holloway, Daniel E et. al.

Solution structure and small angle scattering analysis of TraI (381-569).
score: 4.1598999, Proteins, 2012, Wright, Nathan T et. al.

Identification of Unknown Protein Function Using Metabolite Cocktail Screening
score: 4.1597366, Structure, 2012, Shumilin, Igor A. et. al.

Identification of Unknown Protein Function Using Metabolite Cocktail Screening
score: 4.1597366, Structure, 2012, Shumilin, Igor A. et. al.

Solution Structure ofKurtoxin: A Gating ModifierSelective for Cav3 Voltage-Gated Ca 2+ Channels
score: 4.1575524, Biochemistry, 2012, Lee, Chul Won et. al.

Strategy for supplementing structure calculations using limited data with hydrophobic distance restraints.
score: 4.153621, Proteins, 2004, Alexandrescu, Andrei T

The Structural Domains of Pseudomonas aeruginosa Phosphorylcholine Phosphatase Cooperate in Substrate Hydrolysis: 3D Structure and Enzymatic Mechanism
score: 4.1533297, Journal of Molecular Biology, 2012, Infantes, Lourdes et. al.

The Structural Domains of Pseudomonas aeruginosa Phosphorylcholine Phosphatase Cooperate in Substrate Hydrolysis: 3D Structure and Enzymatic Mechanism
score: 4.1533297, Journal of Molecular Biology, 2012, Infantes, Lourdes et. al.

The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin
score: 4.1518719, PLoS Biology, 2013, Grigoriu, Simina et. al.

Structural basis of the auto-inhibition mechanism of nonreceptor tyrosine kinase PTK6
score: 4.1478315, Biochemical and Biophysical Research Communications, 2009, Ko, Sunggeon et. al.

Coupling of the nucleotide incision and 3′ → 5′ exonuclease activities in Escherichia coli endonuclease IV: Structural and genetic evidences
score: 4.1431665, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2010, Golan, Gali et. al.

High-definition NMR structure of PED/PEA-15 death effector domain reveals details of key polar side chain interactions
score: 4.1413859, Biochemical and Biophysical Research Communications, 2012, Twomey, Edward C.; Wei, Yufeng

Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: Towards the design of higher-affinity inhibitors
score: 4.1336943, BMC Structural Biology, 2008, Hazan, Corinne et. al.

Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase.
score: 4.1295097, ChemMedChem, 2011, Hampton, Shahienaz E et. al.

Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors.
score: 4.128885, Journal of virology, 2012, Zhu, Xueyong et. al.

Crystallographic analysis of trypsin-G226A
score: 4.1283906, Journal of Molecular Biology, 1991, Wilke, Marjorie E. et. al.

X-ray structure of the fourth type of archaeal tRNA splicing endonuclease: insights into the evolution of a novel three-unit composition and a unique loop involved in broad substrate specificity
score: 4.1261463, Nucleic Acids Research, 2012, Hirata, Akira et. al.

Regulation of Protein Kinases
score: 4.1253393, Molecular Cell, 2004, Nolen, Brad; Taylor, Susan; Ghosh, Gourisankar

Structural genomics approach to drug discovery for Mycobacterium tuberculosis
score: 4.1253377, Current Opinion in Microbiology, 2009, Ioerger, Thomas R; Sacchettini, James C

Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine
score: 4.1242552, Structure, 2012, Pan, Jianjun et. al.

Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9
score: 4.1241035, Cell Reports, 2012, Hadders, Michael A. et. al.

Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9
score: 4.1241035, Cell Reports, 2012, Hadders, Michael A. et. al.

Structural Basis for ASPP2 Recognition by the Tumor Suppressor p73
score: 4.1199749, Journal of Molecular Biology, 2012, Canning, Peter; von Delft, Frank; Bullock, Alex N.

The crystal structure of the iron-free cytochrome c peroxidase and its implication for the enzymatic mechanism
score: 4.1185282, FEBS Letters, 1994, Su, Xiao-Dong; Yonetani, Takashi; Skoglund, Ulf

Crucial Steps in the Structure Determination of the Na +/H + Antiporter NhaA in its Native Conformation
score: 4.1176759, Journal of Molecular Biology, 2006, Screpanti, Emanuela et. al.

An essential serotype recognition pocket on phage P22 tailspike protein forces Salmonella enterica serovar Paratyphi A O-antigen fragments to bind as nonsolution conformers.
score: 4.1176708, Glycobiology, 2013, Andres, Dorothee et. al.

Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity.
score: 4.1167564, Nucleic acids research, 2012, Lunde, Bradley M; Magler, Iris; Meinhart, Anton

Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel.
score: 4.1166417, Nature, 2012, Zhang, Xu et. al.

Structural Plasticity and the Evolution of Antibody Affinity and Specificity
score: 4.1157296, Journal of Molecular Biology, 2003, Yin, Jun et. al.

A role for inter-subunit interactions in maintaining SAGA deubiquitinating module structure and activity
score: 4.1124769, Structure, 2012, Samara, Nadine L.; Ringel, Alison E.; Wolberger, Cynthia

Crystal structure of the cysteine protease interleukin-1β-converting enzyme: A (p20/p10) 2 homodimer
score: 4.109161, Cell, 1994, Walker, N.P.C. et. al.

Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion
score: 4.1073682, Structure, 1994, Jäger, Joachim et. al.

A Structure-Based Strategy for Epitope Discovery in Burkholderia pseudomallei OppA Antigen
score: 4.1068796, Structure, 2013, Lassaux, Patricia et. al.

Structure of Phosphorylated SF1 Bound to U2AF65in an Essential Splicing Factor Complex
score: 4.1062865, Structure, 2013, Wang, Wenhua et. al.

Structure of Phosphorylated SF1 Bound to U2AF65in an Essential Splicing Factor Complex
score: 4.1062865, Structure, 2013, Wang, Wenhua et. al.

Protein engineering
score: 4.1055934, Current Opinion in Biotechnology, 1994,

Structural Metals in the Group I Intron: A Ribozyme with a Multiple Metal Ion Core
score: 4.10255, Journal of Molecular Biology, 2007, Stahley, Mary R. et. al.

Structural flexibility and the positive charges are the key factors in bacterial cell selectivity and membrane penetration of peptoid-substituted analog of Piscidin 1
score: 4.0991133, BBA - Biomembranes, 2010, Kim, Jin-Kyoung et. al.

The solution structure of the human ETS1-DNA complex reveals a novel mode of binding and true side chain intercalation
score: 4.0972515, Cell, 1995, Werner, Milton H. et. al.

Improved Structural Characterizations of the drkN SH3 Domain Unfolded State Suggest a Compact Ensemble with Native-like and Non-native Structure
score: 4.0942613, Journal of Molecular Biology, 2007, Marsh, Joseph A. et. al.

A fluorescence polarization assay for inhibitors of Hsp90
score: 4.0915779, Analytical Biochemistry, 2006, Howes, R. et. al.

Bifunctional inhibitors of the trypsin-like activity of eukaryotic proteasomes
score: 4.0858256, Chemistry & Biology, 1999, Loidl, Günther et. al.

Structure of a non-camelized human M12-V H domain at 1.5 Å resolution
score: 4.0832533, Journal of Structural Biology, 2005, Gaur, Rajneesh Kumar

Structure of the Third Intracellular Loop of the Vasopressin V2 Receptor and Conformational Changes upon Binding to gC1qR
score: 4.0828295, Journal of Molecular Biology, 2009, Bellot, Gaëtan et. al.

The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.
score: 4.0825013, Proceedings of the National Academy of Sciences of the United States of America, 1999, Sommerhoff, C P et. al.

Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3.
score: 4.0810935, Proceedings of the National Academy of Sciences of the United States of America, 2012, Deng, Lu et. al.

Crystal structure of human α-lactalbumin at 1·7 Å resolution
score: 4.0777211, Journal of Molecular Biology, 1991, Ravi Acharya, K. et. al.

Structural Reorganization Triggered by Charging of Lys Residues in the Hydrophobic Interior of a Protein
score: 4.0763529, Structure, 2012, Chimenti, Michael S. et. al.

Crystal structure of an extracellular fragment of the rat CD4 receptor containing domains 3 and 4
score: 4.0655632, Structure, 1994, Lange, Gudrun et. al.

Rapid protein fold determination using unassigned NMR data.
score: 4.0650151, Proceedings of the National Academy of Sciences of the United States of America, 2003, Meiler, Jens; Baker, David

A thermophilic mini-chaperonin contains a conserved polypeptide-binding surface: combined crystallographic and NMR studies of the GroEL apical domain with implications for substrate interactions 1 1 Edited by A. R. Fersht
score: 4.0609682, Journal of Molecular Biology, 2001, Hua, Qing-xin et. al.

U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
score: 4.0584802, Nucleic acids research, 2013, Jenkins, Jermaine L et. al.

Modifying the Substrate Specificity of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1 to Target Thrombin
score: 4.055448, PLoS ONE, 2010, Giri, Pankaj Kumar et. al.

The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates.
score: 4.0529028, Proceedings of the National Academy of Sciences of the United States of America, 2012, Iwata, Momi et. al.

Inactivation of the Heme Degrading Enzyme IsdI by an Active Site Substitution That Diminishes Heme Ruffling *
score: 4.0497919, The Journal of Biological Chemistry, 2012, Ukpabi, Georgia et. al.

The repeat domain of the type III effector protein PthA shows a TPR-like structure and undergoes conformational changes upon DNA interaction.
score: 4.0472222, Proteins, 2010, Murakami, Mário Tyago et. al.

A study of the structure-activity relationship for diazaborine inhibition of Escherichia coli enoyl-ACP reductase 1 1 Edited by I. A. Wilson
score: 4.0424276, Journal of Molecular Biology, 2001, Levy, Colin W et. al.

Solution structure of the cold-shock-like protein from Rickettsia rickettsii
score: 4.0423892, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2012, Gerarden, Kyle P. et. al.

RNA structure at high resolution.
score: 4.0411793, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1995, Shen, L X; Cai, Z; Tinoco, I

Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor RIG-I
score: 4.0388009, Structure, 2012, Luo, Dahai; Kohlway, Andrew; Vela, Adriana; Pyle, Anna Marie

Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor RIG-I
score: 4.0388009, Structure, 2012, Luo, Dahai; Kohlway, Andrew; Vela, Adriana; Pyle, Anna Marie

The Plug Domain of the SecY Protein Stabilizes the Closed State of the Translocation Channel and Maintains a Membrane Seal
score: 4.0375027, Molecular Cell, 2007, Li, Weikai et. al.

Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants
score: 4.0335212, Cell, 2012, Du, Jiamu et. al.

Protein Structures at Atomic Resolution
score: 4.0304271, Methods in Enzymology, 2003, Dauter, Zbigniew

Structural insight into the substrate- and dioxygen-binding manner in the catalytic cycle of rieske nonheme iron oxygenase system, carbazole 1,9a-dioxygenase
score: 4.0275741, BMC Structural Biology, 2012, Ashikawa, Yuji et. al.

Structure and function of 3α-hydroxysteroid dehydrogenase
score: 4.0259568, Steroids, 1997, Penning, Trevor M. et. al.

Structure Analysis of a New Psychrophilic Marine Protease
score: 4.0254366, PLoS ONE, 2011, Zhang, Si-Cai et. al.

Structure of a Switchable Subtilisin Complexed with a Substrate and with the Activator Azide †
score: 4.0250776, Biochemistry, 2009, Gallagher, Travis et. al.

Central base pair flipping and discrimination by PspGI
score: 4.0240267, Nucleic Acids Research, 2008, Szczepanowski, Roman H. et. al.

The Dimer Interface of the Membrane Type 1 Matrix Metalloproteinase Hemopexin Domain
score: 4.0237405, The Journal of Biological Chemistry, 2010, Tochowicz, Anna et. al.

Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region
score: 4.0230462, Biochemical Journal, 2012, Gong, Deshun et. al.

Solution structure of the general transcription factor 2I domain in mouse TFII-I protein.
score: 4.015551, Protein science : a publication of the Protein Society, 2007, Doi-Katayama, Yukiko et. al.

Who checks the checkers? four validation tools applied to eight atomic resolution structures 1 1 Edited by I. A. Wilson
score: 4.0128019, Journal of Molecular Biology, 1998,

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development
score: 4.0127083, Cell, 2012, Xu, Yufei et. al.

An atomic model of the outer layer of the bluetongue virus core derived from X-ray crystallography and electron cryomicroscopy
score: 4.0109402, Structure, 1997, Grimes, Jonathan M et. al.

Purification and crystallization of recombinant human TNF-like ligand TL1A
score: 4.0109254, Cytokine, 2007, Jin, Tengchuan et. al.

Crystal Structure of a Ba2+-Bound Gating Ring Reveals Elementary Steps in RCK Domain Activation
score: 4.0087435, Structure, 2012, Smith, Frank J. et. al.

Crystal Structure of a Ba2+-Bound Gating Ring Reveals Elementary Steps in RCK Domain Activation
score: 4.0087435, Structure, 2012, Smith, Frank J. et. al.

Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.
score: 4.0083592, Proceedings of the National Academy of Sciences of the United States of America, 2012, Batt, Sarah M et. al.

Structure of a hepatitis C virus RNA domain in complex with a translation inhibitor reveals a binding mode reminiscent of riboswitches.
score: 4.0083356, Proceedings of the National Academy of Sciences of the United States of America, 2012, Dibrov, Sergey M et. al.

The Neurobiologist's Guide to Structural Biology: A Primer on Why Macromolecular Structure Matters and How to Evaluate Structural Data
score: 4.005347, Neuron, 2007, Minor, Daniel L.

Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber.
score: 4.0023956, The EMBO journal, 2010, Cha, Sun-Shin et. al.

Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation
score: 4.0023297, Bioorganic & Medicinal Chemistry, 2012, Parmenopoulou, Vanessa et. al.

Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation
score: 4.0023297, Bioorganic & Medicinal Chemistry, 2012, Parmenopoulou, Vanessa et. al.

The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins
score: 4.0021222, Journal of Structural and Functional Genomics, 2007, Gileadi, Opher et. al.

Slicing a protease: structural features of the ATP-dependent Lon proteases gleaned from investigations of isolated domains.
score: 4.0020791, Protein science : a publication of the Protein Society, 2006, Rotanova, Tatyana V et. al.

Structure of AAV-DJ, a Retargeted Gene Therapy Vector: Cryo-Electron Microscopy at 4.5 Å Resolution
score: 3.9993289, Structure, 2012, Lerch, Thomas F. et. al.

Structural similarity of cytochrome c 2 from Rhodopseudomonas viridis to mitochondrial cytochromes c revealed by its crystal structure at 2.7 Å resolution
score: 3.9971554, FEBS Letters, 1994, Sogabe, Satoshi et. al.

Biochemical and Structural Evidence in Support of a Coherent Model for the Formation of the Double-Helical Influenza A Virus Ribonucleoprotein
score: 3.9958393, mBio, 2012, Ye, Qiaozhen et. al.

Revisiting the NMR Structure of the Ultrafast Downhill Folding Protein gpW from Bacteriophage λ
score: 3.9900999, PLoS ONE, 2011, Sborgi, Lorenzo; Verma, Abhinav; Muñoz, Victor; de Alba, Eva

An example of a protein ligand found by database mining: description of the docking method and its verification by a 2.3 Å X-ray structure of a Thrombin-Ligand complex 1 1 Edited by F. Cohen
score: 3.9881072, Journal of Molecular Biology, 1998, Burkhard, P; Taylor, P; Walkinshaw, M.D

Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain
score: 3.9871231, Biochimie, 2012, Galea, Charles A. et. al.

Proteins
score: 3.9860038, Current Opinion in Structural Biology, 1997,

A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity
score: 3.9855475, Structure, 2012, Samara, Nadine L.; Ringel, Alison E.; Wolberger, Cynthia

Investigation of RNA structure in satellite panicum mosaic virus
score: 3.9847495, Virology, 2006, Makino, D.L.; Day, J.; Larson, S.B.; McPherson, A.

Crystal structure of xenotropic murine leukaemia virus-related virus (XMRV) ribonuclease H
score: 3.984493, Bioscience Reports, 2012, Kim, Ju Hee et. al.

Structural characterization and computer-aided optimization of a small-molecule inhibitor of the Arp2/3 complex, a key regulator of the actin cytoskeleton.
score: 3.9841397, ChemMedChem, 2012, Baggett, Andrew W et. al.

Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.
score: 3.980298, The EMBO journal, 2004, Meyer, Philippe et. al.

Crystal structure of Onconase at 1.1 Å resolution – insights into substrate binding and collective motion
score: 3.9801124, The Febs Journal, 2011, Holloway, Daniel E et. al.

Atomic resolution of the crystal structure of the hyperthermophilic family 12 endocellulase and stabilizing role of the DxDxDG calcium-binding motif in Pyrococcus furiosus
score: 3.9794133, FEBS Letters, 2012, Kim, Han-Woo; Kataoka, Misumi; Ishikawa, Kazuhiko

The loops facing the active site of prolyl oligopeptidase are crucial components in substrate gating and specificity
score: 3.9788942, BBA - Proteins and Proteomics, 2013, Szeltner, Zoltán et. al.

The loops facing the active site of prolyl oligopeptidase are crucial components in substrate gating and specificity
score: 3.9788942, BBA - Proteins and Proteomics, 2013, Szeltner, Zoltán et. al.

Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein.
score: 3.9765976, Proceedings of the National Academy of Sciences of the United States of America, 2012, Welch, Brett D et. al.

Crystallographic studies of quadruplex nucleic acids
score: 3.9734348, Methods, 2007, Campbell, Nancy H.; Parkinson, Gary N.

Crystal structure of chicken riboflavin-binding protein.
score: 3.9732985, The EMBO journal, 1997, Monaco, H L

Glutathione Biosynthesis in Bacteria by Bifunctional GshF Is Driven by a Modular Structure Featuring a Novel Hybrid ATP-Grasp Fold
score: 3.9695303, Journal of Molecular Biology, 2012, Stout, Jan et. al.

Three-dimensional structure of acetylcholinesterase and of its complexes with anticholinesterase drugs
score: 3.9681962, Chemico-Biological Interactions, 1993, Sussman, J.L.; Harel, M.; Silman, I.

Structure of AAV-DJ, a Retargeted Gene Therapy Vector: Cryo-Electron Microscopy at 4.5Å resolution
score: 3.9645368, Structure, 2012, Lerch, Thomas F. et. al.

Structure and Dynamics of CTX-M Enzymes Reveal Insights into Substrate Accommodation by Extended-spectrum β-Lactamases
score: 3.9634518, Journal of Molecular Biology, 2008, Delmas, Julien et. al.

Functional implications of the structure of the murine parvovirus, minute virus of mice
score: 3.9623536, Structure, 1998, Agbandje-McKenna, Mavis et. al.

Solution structure of the carboxy-terminal Tudor domain from human Coilin
score: 3.9605315, FEBS Letters, 2010, Shanbhag, Riya et. al.

Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA.
score: 3.9598065, The EMBO journal, 2007, Sasaki, Kaori et. al.

Solution structure of a type 2 module from fibronectin: implications for the structure and function of the gelatin-binding domain
score: 3.9594375, Structure, 1997, Pickford, Andrew R et. al.

Structure of malonamidase E2 reveals a novel Ser-cisSer-Lys catalytic triad in a new serine hydrolase fold that is prevalent in nature.
score: 3.958002, The EMBO journal, 2002, Shin, Sejeong et. al.

The novel structure of a cytosolic M14 metallocarboxypeptidase (CCP) from Pseudomonas aeruginosa: a model for mammalian CCPs.
score: 3.9568621, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Otero, Anabel et. al.

Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein Interface
score: 3.9559386, Chemistry & Biology, 2012, Van Molle, Inge et. al.

Crystal structure of the two N-terminal RRM domains of Pub1 and the poly(U)-binding properties of Pub1
score: 3.955079, Journal of Structural Biology, 2010, Li, Heng et. al.

Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.
score: 3.9534881, Nature, 2009, Barends, Thomas R M et. al.

A Conformational Switch in the Active Site of BT_2972, a Methyltransferase from an Antibiotic Resistant Pathogen B. thetaiotaomicron
score: 3.94841, PLoS ONE, 2011, Kumar, Veerendra; Sivaraman, J.

The structure of maize polyamine oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation.
score: 3.947762, The FEBS journal, 2011, Fiorillo, Annarita et. al.

Crystal structure of phosphoethanolamine methyltransferase from Plasmodium falciparum in complex with amodiaquine
score: 3.9466522, Bioorganic & Medicinal Chemistry Letters, 2012, Lee, Soon Goo; Alpert, Tara D.; Jez, Joseph M.

Characterization of Dual Substrate Binding Sites in the Homodimeric Structure of Escherichia coli mRNA Interferase MazF
score: 3.9446078, Journal of Molecular Biology, 2006, Li, Guang-Yao et. al.

Structural Analysis of the UBA Domain of X-linked Inhibitor of Apoptosis Protein Reveals Different Surfaces for Ubiquitin-Binding and Self-Association
score: 3.9439214, PLoS ONE, 2011, Tse, Man Kit et. al.

Cloning, production, purification and preliminary crystallographic analysis of a glycosidase from the food lactic acid bacterium Lactobacillus plantarum CECT 748 T
score: 3.9422156, Protein Expression and Purification, 2009, Acebrón, Iván et. al.

Invited Review: β-Lactoglobulin: Binding Properties, Structure, and Function
score: 3.9416608, Journal of Dairy Science, 2004, Kontopidis, G.; Holt, C.; Sawyer, L.

Intramolecular Dynamics of Low Molecular Weight Protein Tyrosine Phosphatase in Monomer–Dimer Equilibrium Studied by NMR: A Model for Changes in Dynamics upon Target Binding
score: 3.940842, Journal of Molecular Biology, 2002, Åkerud, Tomas et. al.

Structural and Functional Analysis of Validoxylamine A 7′-phosphate Synthase ValL Involved in Validamycin A Biosynthesis
score: 3.9402894, PLoS ONE, 2012, Zheng, Lina et. al.

The structural basis of the recognition of phenylalanine and pterin cofactors by phenylalanine hydroxylase: implications for the catalytic mechanism 1 1 Edited by D. C. Rees
score: 3.9401683, Journal of Molecular Biology, 1999, Teigen, Knut; Frøystein, Nils Åge; Martı́nez, Aurora

Solution NMR in structural genomics
score: 3.9400307, Current Opinion in Structural Biology, 2006, Yee, Adelinda; Gutmanas, Aleksandras; Arrowsmith, Cheryl H

NMR structure of the peptidyl-tRNA hydrolase domain from Pseudomonas syringae expands the structural coverage of the hydrolysis domains of class 1 peptide chain release factors.
score: 3.9379719, Proteins, 2008, Singarapu, Kiran Kumar et. al.

Molecular Fragment Replacement Approach to Protein Structure Determination by Chemical Shift and Dipolar Homology Database Mining
score: 3.9371111, Methods in Enzymology, 2005, Kontaxis, Georg; Delaglio, Frank; Bax, Ad

Molecular Fragment Replacement Approach to Protein Structure Determination by Chemical Shift and Dipolar Homology Database Mining
score: 3.9371111, Methods in Enzymology, 2005, Kontaxis, Georg; Delaglio, Frank; Bax, Ad

Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: Implications for cellular potency and selectivity over insulin receptor
score: 3.9363735, Biochemical Pharmacology, 2009, Wood, Edgar R. et. al.

Structural and mechanistic investigations on Salmonella typhimurium acetate kinase (AckA): identification of a putative ligand binding pocket at the dimeric interface
score: 3.9318076, BMC Structural Biology, 2012, Chittori, Sagar; Savithri, Handanahal S; Murthy, Mathur RN

Structure of WbdD: a bifunctional kinase and methyltransferase that regulates the chain length of the O antigen in Escherichia coli O9a
score: 3.9314143, Molecular Microbiology, 2012, Hagelueken, Gregor et. al.

Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH.
score: 3.9290971, Proceedings of the National Academy of Sciences of the United States of America, 2012, Englert, Markus et. al.

Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation
score: 3.9281996, Bioorganic & Medicinal Chemistry, 2012, Parmenopoulou, Vanessa et. al.

Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase: structure, catalytic mechanism and targeted inhibitor design
score: 3.9281936, FEBS Letters, 1998, Souza, D.H.F et. al.

The ‘fingerprint’ that X-rays can leave on structures
score: 3.9256586, Structure, 2000, Ravelli, Raimond BG; McSweeney, Sean M

Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations
score: 3.9255772, Biochemical and Biophysical Research Communications, 2010, Singla, Nikhil et. al.

1.7 Å X-ray structure of the periplasmic ribose receptor from Escherichia coli
score: 3.9208452, Journal of Molecular Biology, 1992, Mowbray, Sherry L.; Cole, L.Brent

Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor.
score: 3.9154644, Proceedings of the National Academy of Sciences of the United States of America, 2009, Akiyama, Masashi et. al.

Assembly of Q{beta} viral RNA polymerase with host translational elongation factors EF-Tu and -Ts.
score: 3.915111, Proceedings of the National Academy of Sciences of the United States of America, 2010, Takeshita, Daijiro; Tomita, Kozo

Combinatorial Design of an Anticalin Directed against the Extra-Domain B for the Specific Targeting of Oncofetal Fibronectin
score: 3.9137552, Journal of Molecular Biology, 2013, Gebauer, Michaela et. al.

Molecular interaction of flagellar export chaperone FliS and cochaperone HP1076 in Helicobacter pylori.
score: 3.9104713, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Lam, Wendy Wai Ling et. al.

Crystal Structure of UBA2 ufd -Ubc9: Insights into E1-E2 Interactions in Sumo Pathways
score: 3.9087826, PLoS ONE, 2010, Wang, Jing et. al.

Structure based mechanism of the Ca(2+)-induced release of coelenterazine from the Renilla binding protein.
score: 3.9071722, Proteins, 2009, Stepanyuk, Galina A et. al.

Specificity of Staphyloferrin B Recognition by the SirA Receptor from Staphylococcus aureus *
score: 3.9048524, The Journal of Biological Chemistry, 2010, Grigg, Jason C. et. al.

An assessment of the accuracy of methods for predicting hydrogen positions in protein structures.
score: 3.9043447, Proteins, 2005, Forrest, Lucy R; Honig, Barry

Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins And Its Mode of Sphingomyelin Recognition
score: 3.9031736, Structure, 2012, De Colibus, Luigi et. al.

Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA.
score: 3.9014902, Nature structural & molecular biology, 2011, Gong, Yong et. al.

Crystal structure of Rab6A′(Q72L) mutant reveals unexpected GDP/Mg2+ binding with opened GTP-binding domain
score: 3.9001376, Biochemical and Biophysical Research Communications, 2012, Shin, Young-Cheul et. al.

Crystal structure of periplasmic catecholate-siderophore binding protein VctP from Vibrio cholerae at 1.7Å resolution
score: 3.897709, FEBS Letters, 2012, Liu, Xiuhua et. al.

Crystal structure of periplasmic catecholate-siderophore binding protein VctP from Vibrio cholerae at 1.7Å resolution
score: 3.897709, FEBS Letters, 2012, Liu, Xiuhua et. al.

An Alternative Conformation of the T-Cell Receptor α Constant Region
score: 3.896427, Journal of Molecular Biology, 2010, van Boxel, Gijs I. et. al.

Protein crystallization by capillary counterdiffusion for applied crystallographic structure determination
score: 3.8961893, Journal of Structural Biology, 2003, Ng, Joseph D; Gavira, José A; Garcı́a-Ruı́z, Juan M

Validation tools: can they indicate the information content of macromolecular crystal structures?
score: 3.8961081, Structure, 1998, Dodson, EJ et. al.

An Autoinhibited Noncanonical Mechanism of GTP Hydrolysis by Rheb Maintains mTORC1 Homeostasis
score: 3.8950415, Structure, 2012, Mazhab-Jafari, Mohammad T. et. al.

Assembly of Acanthamoeba Myosin-II Minifilaments. Model of Anti-parallel Dimers Based on EM and X-ray Diffraction of 2D and 3D Crystals
score: 3.8945877, Journal of Molecular Biology, 2005, Turbedsky, Kirsi; Pollard, Thomas D.; Yeager, Mark

Molecular docking/dynamics studies of Aurora A kinase inhibitors
score: 3.8944862, Journal of Molecular Graphics and Modelling, 2008, Talele, Tanaji T.; McLaughlin, Mark L.

Hepatitis C Virus NS3 Protease Requires Its NS4A Cofactor Peptide for Optimal Binding of a Boronic Acid Inhibitor as Shown by NMR
score: 3.8941753, Chemistry & Biology, 2002, Archer, Sharon J et. al.

The crystal structure of isopenicillin N synthase with a dipeptide substrate analogue
score: 3.8931075, Archives of Biochemistry and Biophysics, 2013, Daruzzaman, Adam et. al.

Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
score: 3.892492, Proceedings of the National Academy of Sciences of the United States of America, 2012, Buck-Koehntop, Bethany A et. al.

The P22 Tail Machine at Subnanometer Resolution Reveals the Architecture of an Infection Conduit
score: 3.8900898, Structure, 2009, Lander, Gabriel C. et. al.

The nitrite reductase from Pseudomonas aeruginosa: essential role of two active-site histidines in the catalytic and structural properties.
score: 3.8897665, Proceedings of the National Academy of Sciences of the United States of America, 2001, Cutruzzola, F et. al.

Two Structurally Independent Domains of E. coli NusG Create Regulatory Plasticity via Distinct Interactions with RNA Polymerase and Regulators
score: 3.8890298, Journal of Molecular Biology, 2009, Mooney, Rachel Anne et. al.

Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases *
score: 3.8883906, The Journal of Biological Chemistry, 2013, Canning, Peter et. al.

1,3-Dioxane-4,6-dione-5-carboxamide-based inhibitors of human group IIa phospholipase A 2: X-ray structure of the complex and interfacial selection of inhibitors from a structural library
score: 3.8873529, Bioorganic & Medicinal Chemistry Letters, 1999, Bryant, M.D. et. al.

The solution structure of the prototype foamy virus RNase H domain indicates an important role of the basic loop in substrate binding
score: 3.8870941, Retrovirology, 2012, Leo, Berit et. al.

The Murine Coronavirus Hemagglutinin-esterase Receptor-binding Site: A Major Shift in Ligand Specificity through Modest Changes in Architecture
score: 3.8836887, PLoS Pathogens, 2012, Langereis, Martijn A. et. al.

Structure and Function of α‐Tocopherol Transfer Protein: Implications for Vitamin E Metabolism and AVED
score: 3.8815351, Vitamins and Hormones, 2007, Christopher Min, K.

Structure and Function of α‐Tocopherol Transfer Protein: Implications for Vitamin E Metabolism and AVED
score: 3.8815351, Vitamins and Hormones, 2007, Christopher Min, K.

Structure and Function of α‐Tocopherol Transfer Protein: Implications for Vitamin E Metabolism and AVED
score: 3.8815351, Vitamins and Hormones, 2007, Christopher Min, K.

The structure of putative N-acetyl glutamate kinase from Thermus thermophilus reveals an intermediate active site conformation of the enzyme
score: 3.8799909, Biochemical and Biophysical Research Communications, 2012, Sundaresan, Ramya et. al.

The structure of putative N-acetyl glutamate kinase from Thermus thermophilus reveals an intermediate active site conformation of the enzyme
score: 3.8799909, Biochemical and Biophysical Research Communications, 2012, Sundaresan, Ramya et. al.

Structural mechanism of JH delivery in hemolymph by JHBP of silkworm, Bombyx mori
score: 3.8770207, Scientific Reports, 2011, Suzuki, Rintaro et. al.

1α,25(OH) 2 -3-Epi-Vitamin D 3 , a Natural Physiological Metabolite of Vitamin D 3 : Its Synthesis, Biological Activity and Crystal Structure with Its Receptor
score: 3.8765772, PLoS ONE, 2011, Molnár, Ferdinand et. al.

Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity 1 1 Edited by F.E.Cohen
score: 3.8759053, Journal of Molecular Biology, 1997, Wuttke, Deborah S. et. al.

The Fe-type nitrile hydratase from Comamonas testosteroni Ni1 does not require an activator accessory protein for expression in Escherichia coli
score: 3.8735984, Biochemical and Biophysical Research Communications, 2012, Kuhn, Misty L. et. al.

Disease mutations in the Ryanodine Receptor Central Region: Crystal structures of a phosphorylation hot spot domain
score: 3.8734968, Structure, 2012, Yuchi, Zhiguang; Lau, Kelvin; Van Petegem, Filip

The catalytic site of serine proteinases as a specific binding cavity for xenon
score: 3.872057, Structure, 1995, Schiltz, Marc et. al.

Structural and Functional Characterization of an SMC-like Protein RecN: New Insights into Double-Strand Break Repair
score: 3.8715254, Structure, 2012, Pellegrino, Simone et. al.

Interdomain allostery promotes assembly of the polyA mRNA complex with PABP and eIF4G
score: 3.8688756, Molecular Cell, 2012, Safaee, Nozhat et. al.

Bisubstrate analog inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New lead exhibits a distinct binding mode
score: 3.8680422, Bioorganic & Medicinal Chemistry, 2012, Shi, Genbin et. al.

Variations of subunit {epsilon} of the Mycobacterium tuberculosis F1FO ATP synthase and a novel model for mechanism of action of the TB drug TMC207.
score: 3.8677673, Antimicrobial agents and chemotherapy, 2012, Biukovic, Goran et. al.

Structural basis for the recognition of Asef by adenomatous polyposis coli.
score: 3.8676789, Cell research, 2012, Zhang, Zhenyi et. al.

A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants
score: 3.8670714, Retrovirology, 2012, Johnson, Barry C et. al.

Structural and Functional Studies of an Intermediate on the Pathway to Operator Binding by Escherichia coli MetJ
score: 3.8654891, Journal of Molecular Biology, 2002, He, Yi-Yuan et. al.

Crystal structure of human RANKL complexed with its decoy receptor osteoprotegerin.
score: 3.8630029, Journal of immunology (Baltimore, Md. : 1950), 2012, Luan, Xudong et. al.

Structure of a novel thrombin inhibitor with an uncharged d-amino acid as P1 residue
score: 3.8627923, European Journal of Medicinal Chemistry, 2008, Friedrich, Rainer et. al.

The cellulose-binding domains from Cellulomonas fimi β-1,4-glucanase CenC bind nitroxide spin-labeled cellooligosaccharides in multiple orientations 1 1 Edited by P. E. Wright
score: 3.8624876, Journal of Molecular Biology, 1999, Johnson, Philip E. et. al.

Structure-based development of bacterial nitroreductase against nitrobenzodiazepine-induced hypnosis
score: 3.8617741, Biochemical Pharmacology, 2012, LinWu, Shiuan-Woei et. al.

Protein and RNA Dynamics Play Key Roles in Determining the Specific Recognition of GU-rich Polyadenylation Regulatory Elements by Human Cstf-64 Protein
score: 3.8586677, Journal of Molecular Biology, 2005, Deka, Pritilekha et. al.

Solution structure of the phytotoxic protein PcF: the first characterized member of the Phytophthora PcF toxin family.
score: 3.8581843, Protein science : a publication of the Protein Society, 2009, Nicastro, Giuseppe et. al.

Three-dimensional structure of a viral genome-delivery portal vertex
score: 3.857902, Nature structural & molecular biology, 2011, Olia, Adam S. et. al.

Crystal Structure of Periplasmic Catecholate-Siderophore Binding Protein VctP from Vibrio cholerae at 1.7 Å Resolution
score: 3.854036, FEBS Letters, 2012, Liu, Xiuhua et. al.

Deciphering complement mechanisms: The contributions of structural biology
score: 3.8537191, Molecular Immunology, 2007, Arlaud, Gérard J. et. al.

Crystal structure of tarocystatin–papain complex: implications for the inhibition property of group-2 phytocystatins
score: 3.8515239, Planta, 2011, Chu, Ming-Hung et. al.

RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor
score: 3.8500725, Structure, 2012, Nelson, Christopher A. et. al.

RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor
score: 3.8500725, Structure, 2012, Nelson, Christopher A. et. al.

Determination of solution structure and lipid micelle location of an engineered membrane peptide by using one NMR experiment and one sample
score: 3.8483141, BBA - Biomembranes, 2007, Wang, Guangshun

Development of N-2,4-pyrimidine- N-phenyl- N′-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 2
score: 3.8406531, Bioorganic & Medicinal Chemistry Letters, 2006, Maier, Jennifer A. et. al.

Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance
score: 3.8393799, Cell Reports, 2012, Schumacher, Maria A. et. al.

Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance
score: 3.8393799, Cell Reports, 2012, Schumacher, Maria A. et. al.

Biochemical and structural characterization of 5′-methylthioadenosine nucleosidases from Arabidopsis thaliana
score: 3.8392072, Biochemical and Biophysical Research Communications, 2009, Park, Eun Young et. al.

The solution structure of ribosomal protein S4 delta41 reveals two subdomains and a positively charged surface that may interact with RNA.
score: 3.8381923, The EMBO journal, 1998, Markus, M A; Gerstner, R B; Draper, D E; Torchia, D A

β-lactamase TEM1 of E. coli Crystal structure determination at 2.5 Å resolution
score: 3.8371023, FEBS Letters, 1992, Jelsch, C.; Lenfant, F.; Masson, J.M.; Samama, J.P.

Quantum chemical 13C(alpha) chemical shift calculations for protein NMR structure determination, refinement, and validation.
score: 3.8363176, Proceedings of the National Academy of Sciences of the United States of America, 2008, Vila, Jorge A et. al.

Comparison of the Crystal and Solution Structures of Two RNA Oligonucleotides
score: 3.8346157, Biophysical Journal, 1999, Rife, Jason P. et. al.

Triphenylbutanamines:Kinesin Spindle Protein Inhibitors with in Vivo Antitumor Activity †
score: 3.8338412, Journal of Medicinal Chemistry, 2012, Wang, Fang et. al.

Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly.
score: 3.8305531, Proceedings of the National Academy of Sciences of the United States of America, 2011, Zeytuni, Natalie et. al.

Crystal Structure of PU.1/IRF-4/DNA Ternary Complex
score: 3.8294537, Molecular Cell, 2002, Escalante, Carlos R. et. al.

The guanylate kinase domain of the MAGUK PSD-95 binds dynamically to a conserved motif in MAP1a.
score: 3.8289187, Nature structural & molecular biology, 2007, Reese, Michael L et. al.

Crystal structure of Escherichia coli thymidylate synthase containing bound 5-fluoro-2′-deoxyuridylate and 10-propargyl-5,8-dideazafolate
score: 3.8280792, Journal of Molecular Biology, 1990, Matthews, D.A.; Appelt, K.; Oatley, S.J.; Xuong, Ng.H.

Atomic Resolution Structure of a Succinimide Intermediate in E. coli CheY
score: 3.8280755, Journal of Molecular Biology, 2002, Simonovic, Miljan; Volz, Karl

Collagen adhesin–nanoparticle interaction impairs adhesin's ligand binding mechanism
score: 3.8279817, BBA - General Subjects, 2012, Devi, Aribam Swarmistha et. al.

Collagen adhesin–nanoparticle interaction impairs adhesin's ligand binding mechanism
score: 3.8279817, BBA - General Subjects, 2012, Devi, Aribam Swarmistha et. al.

Collagen adhesin–nanoparticle interaction impairs adhesin's ligand binding mechanism
score: 3.8279817, BBA - General Subjects, 2012, Devi, Aribam Swarmistha et. al.

Salicylate 1,2-Dioxygenase from Pseudaminobacter salicylatoxidans: Crystal Structure of a Peculiar Ring-cleaving Dioxygenase
score: 3.8232542, Journal of Molecular Biology, 2008, Matera, Irene et. al.

Protein purification and preliminary crystallographic analysis of human Lyn tyrosine kinase
score: 3.8192803, Protein Expression and Purification, 2008, Kinoshita, Takayoshi et. al.

Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 A resolution.
score: 3.8179562, Proteins, 2002, Kuhn, Peter et. al.

A new triple-stranded α-helical bundle in solution: the assembling of the cytosolic tail of MHC-associated invariant chain
score: 3.8138375, Structure, 1997, Motta, Andrea et. al.

Structure and disorder in the ribonuclease S-peptide probed by NMR residual dipolar couplings.
score: 3.8129177, Protein science : a publication of the Protein Society, 2003, Alexandrescu, Andrei T; Kammerer, Richard A

Getting to the end of RNA: Structural analysis of protein recognition of 5′ and 3′ termini
score: 3.8127907, BBA - Gene Regulatory Mechanisms, 2009, Curry, Stephen et. al.

Synthesis and biological evaluation of pyrazoline analogues with β-amino acyl group as dipeptidyl peptidase IV inhibitors
score: 3.8126286, European Journal of Medicinal Chemistry, 2008, Jun, Mi Ae et. al.

Identification of the Interactions Critical for Propeptide-Catalyzed Folding of Tk-Subtilisin
score: 3.8086403, Journal of Molecular Biology, 2009, Tanaka, Shun-ichi et. al.

Investigating Terephthalate Biodegradation: Structural Characterization of a Putative Decarboxylating cis-Dihydrodiol Dehydrogenase
score: 3.8084298, Journal of Molecular Biology, 2012, Bains, Jasleen; Wulff, Jeremy E.; Boulanger, Martin J.

An unanticipated architecture of the 750 kD holoenzyme of 3-methylcrotonyl-CoA carboxylase
score: 3.8069935, Nature, 2011, Huang, Christine S.; Ge, Peng; Zhou, Z. Hong; Tong, Liang

Crystal structure of two new bifunctional nonsubstrate type thrombin inhibitors complexed with human alpha-thrombin.
score: 3.806409, Protein science : a publication of the Protein Society, 1996, Féthière, J; Tsuda, Y; Coulombe, R; Konishi, Y; Cygler, M

Use of very long-distance NOEs in a fully deuterated protein: an approach for rapid protein fold determination
score: 3.8057647, Journal of Magnetic Resonance, 2003, Koharudin, Leonardus M.I et. al.

Solution Structure and Characterisation of the Human Pyruvate Dehydrogenase Complex Core Assembly
score: 3.8034496, Journal of Molecular Biology, 2010, Vijayakrishnan, S. et. al.

Diabetes-associated mutations in a beta-cell transcription factor destabilize an antiparallel "mini-zipper" in a dimerization interface.
score: 3.8010237, Proceedings of the National Academy of Sciences of the United States of America, 2000, Hua, Q X et. al.

Structures of Cyanobactin Maturation Enzymes Define a Family of Transamidating Proteases
score: 3.7981419, Chemistry & Biology, 2012, Agarwal, Vinayak et. al.

Structure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex.
score: 3.7975833, The EMBO journal, 2008, Hecker, Arnaud et. al.

Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion.
score: 3.7962818, Proceedings of the National Academy of Sciences of the United States of America, 2012, Samanta, Dibyendu et. al.

Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)
score: 3.7959679, Biochimie, 2010, Goettig, Peter; Magdolen, Viktor; Brandstetter, Hans

Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)
score: 3.7959679, Biochimie, 2010, Goettig, Peter; Magdolen, Viktor; Brandstetter, Hans

Crystal structures of the Jak2 pseudokinase domain and the pathogenic mutant V617F
score: 3.7950742, Nature structural & molecular biology, 2012, Bandaranayake, Rajintha M. et. al.

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat
score: 3.7950554, eLife, 2013, Schulze-Gahmen, Ursula et. al.

NMR-based Model Reveals the Structural Determinants of Mammalian Arylamine N-Acetyltransferase Substrate Specificity
score: 3.7916998, Journal of Molecular Biology, 2006, Zhang, Naixia et. al.

Structure of the α-Actinin–Vinculin Head Domain Complex Determined by Cryo-electron Microscopy
score: 3.787993, Journal of Molecular Biology, 2006, Kelly, Deborah F. et. al.

Structure of Leishmania major cysteine synthase
score: 3.7877032, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2012, Fyfe, Paul K. et. al.

Calmodulin Disrupts the Structure of the HIV-1 MA Protein
score: 3.7864661, Journal of Molecular Biology, 2010, Chow, John Y.H. et. al.

Synergistic Binding of the Phosphorylated S233- and S259-Binding Sites of C-RAF to One 14-3-3ζ Dimer
score: 3.7845953, Journal of Molecular Biology, 2012, Molzan, Manuela; Ottmann, Christian

Synergistic Binding of the Phosphorylated S233- and S259-Binding Sites of C-RAF to One 14-3-3ζ Dimer
score: 3.7845953, Journal of Molecular Biology, 2012, Molzan, Manuela; Ottmann, Christian

Oligomycin frames a common drug-binding site in the ATP synthase.
score: 3.7818265, Proceedings of the National Academy of Sciences of the United States of America, 2012, Symersky, Jindrich et. al.

The BARD1 C-Terminal Domain Structure and Interactions with Polyadenylation Factor CstF-50 †
score: 3.7773294, Biochemistry, 2008, Edwards, Ross A. et. al.

Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition
score: 3.77269, PLoS ONE, 2012, Gandhi, Amit K. et. al.

Origin of the stereospecificity in binding hydroxamates of α- and β-phenylalanine methylamide to thermolysin revealed by the X-ray crystallographic study
score: 3.771807, Bioorganic & Medicinal Chemistry, 2003, Kim, Seung-Jun et. al.

Novel Morpholinone-Based d-Phe-Pro-Arg Mimics as Potential Thrombin Inhibitors: Design, Synthesis, and X-ray Crystal Structure of an Enzyme Inhibitor Complex
score: 3.7704543, Bioorganic & Medicinal Chemistry, 2002, Dahlgren, Anders et. al.

Crystal Structure Analysis of the Polysialic Acid Specific O-Acetyltransferase NeuO
score: 3.7697956, PLoS ONE, 2011, Schulz, Eike C. et. al.

Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex
score: 3.7670683, PLoS Pathogens, 2011, Chen, Yu et. al.

Structural Analysis of the Substrate Recognition Mechanism in O-Phosphoserine Sulfhydrylase from the Hyperthermophilic Archaeon Aeropyrum pernix K1
score: 3.7667964, Journal of Molecular Biology, 2012, Nakamura, Takashi et. al.

Structural Analysis of the Substrate Recognition Mechanism in O-Phosphoserine Sulfhydrylase from the Hyperthermophilic Archaeon Aeropyrum pernix K1
score: 3.7667964, Journal of Molecular Biology, 2012, Nakamura, Takashi et. al.

Structural Analysis of the Substrate Recognition Mechanism in O-Phosphoserine Sulfhydrylase from the Hyperthermophilic Archaeon Aeropyrum pernix K1
score: 3.7667964, Journal of Molecular Biology, 2012, Nakamura, Takashi et. al.

Structural insights into energy regulation of light-harvesting complex CP29 from spinach.
score: 3.766664, Nature structural & molecular biology, 2011, Pan, Xiaowei et. al.

Stereospecific Interactions of Proline Residues in Protein Structures and Complexes
score: 3.7656716, Journal of Molecular Biology, 2003, Bhattacharyya, Rajasri; Chakrabarti, Pinak

The essential role of C-terminal residues in regulating the activity of hepatitis C virus RNA-dependent RNA polymerase
score: 3.7654211, BBA - Proteins and Proteomics, 2002, Adachi, Tsuyoshi et. al.

RNA recognition by transcriptional antiterminators of the BglG/SacY family: functional and structural comparison of the CAT domain from SacY and LicT 1 1 Edited by R. Huber
score: 3.7644765, Journal of Molecular Biology, 1999, Declerck, Nathalie et. al.

Nucleotide-Mediated Conformational Changes of Monomeric Actin and Arp3 Studied by Molecular Dynamics Simulations
score: 3.7641232, Journal of Molecular Biology, 2008, Dalhaimer, Paul; Pollard, Thomas D.; Nolen, Brad J.

Crystal structure of the Escherichia coli Tas protein, an NADP(H)-dependent aldo-keto reductase.
score: 3.7637053, Proteins, 2003, Obmolova, Galina et. al.

Carbohydrates contribute to the interactions between cockroach allergen Bla g 2 and a monoclonal antibody.
score: 3.7626922, Journal of immunology (Baltimore, Md. : 1950), 2011, Li, Mi et. al.

Crystal structure of the cowpox virus encoded NKG2D-ligand OMCP.
score: 3.7592967, Journal of virology, 2012, Lazear, Eric et. al.

The structure of putative N-acetyl glutamate kinase from Thermus thermophilus reveals an intermediate active site conformation of the enzyme
score: 3.7592111, Biochemical and Biophysical Research Communications, 2012, Sundaresan, Ramya et. al.

Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1.
score: 3.7574201, Proceedings of the National Academy of Sciences of the United States of America, 2012, Manka, Szymon W et. al.

Synthesis, structure and imaging of oligodeoxyribonucleotides with tellurium-nucleobase derivatization
score: 3.7562596, Nucleic Acids Research, 2011, Sheng, Jia et. al.

The crystal structure of citrate synthase from the thermophilic Archaeon, Thermoplasma acidophilum
score: 3.7539984, Structure, 1994, Russell, Rupert JM et. al.

Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores
score: 3.7534669, Bioorganic & Medicinal Chemistry, 2009, Kotian, Pravin L. et. al.

Bisubstrate analog inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New lead exhibits a distinct binding mode
score: 3.7520209, Bioorganic & Medicinal Chemistry, 2012, Shi, Genbin et. al.

Crystal structure of Cmr2 suggests a nucleotide cyclase-related enzyme in type III CRISPR-Cas systems
score: 3.7513481, FEBS Letters, 2012, Zhu, Xing; Ye, Keqiong

Characterization of Staphylococcus aureus EssB, an integral membrane component of the Type VII secretion system: atomic resolution crystal structure of the cytoplasmic segment
score: 3.7509793, Biochemical Journal, 2012, Zoltner, Martin et. al.

The Indispensable N-Terminal Half of eIF3j/HCR1 Cooperates with its Structurally Conserved Binding Partner eIF3b/PRT1-RRM and with eIF1A in Stringent AUG Selection
score: 3.7494402, Journal of Molecular Biology, 2010, ElAntak, Latifa et. al.

An unanticipated architecture of the 750-kDa α6β6 holoenzyme of 3-methylcrotonyl-CoA carboxylase.
score: 3.7490777, Nature, 2012, Huang, Christine S; Ge, Peng; Zhou, Z Hong; Tong, Liang

Flexibility of Aromatic Residues in the Active-Site Gorge of Acetylcholinesterase: X-ray versus Molecular Dynamics
score: 3.7463826, Biophysical Journal, 2008, Xu, Yechun et. al.

Weak alignment offers new NMR opportunities to study protein structure and dynamics.
score: 3.745432, Protein science : a publication of the Protein Society, 2003, Bax, Ad

High-Resolution Structure of the Nitrile Reductase QueF Combined with Molecular Simulations Provide Insight into Enzyme Mechanism
score: 3.7446076, Journal of Molecular Biology, 2010, Kim, Youngchang et. al.

Structural basis of PNRC2-mediated link between mRNA surveillance and decapping
score: 3.7442129, Structure, 2012, Lai, Tingfeng et. al.

A Photo-Labile Thioether Linkage to Phycoviolobilin Provides the Foundation for the Blue/Green Photocycles in DXCF-Cyanobacteriochromes
score: 3.7417888, Structure, 2013, Burgie, E. Sethe et. al.

NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU)
score: 3.7412345, Peptides, 2010, Schein, Catherine H. et. al.

Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidinesAre Highly Active CDK9 Inhibitors: Synthesis, X-ray CrystalStructures, Structure–Activity Relationship, and AnticancerActivities
score: 3.7411359, Journal of Medicinal Chemistry, 2013, Shao, Hao et. al.

Structural characterization of human heme oxygenase-1 in complex with azole-based inhibitors
score: 3.7406739, Journal of Inorganic Biochemistry, 2010, Rahman, Mona N. et. al.

Stereochemical punctuation marks in protein structures: glycine and proline containing helix stop signals 1 1 Edited by J. Thornton
score: 3.740482, Journal of Molecular Biology, 1998, Gunasekaran, K et. al.

Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway
score: 3.73924, Archives of Biochemistry and Biophysics, 2012, Lim, Young-Ran et. al.

Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway
score: 3.73924, Archives of Biochemistry and Biophysics, 2012, Lim, Young-Ran et. al.

Oligomeric Structure of the MALT1 Tandem Ig-Like Domains
score: 3.7368303, PLoS ONE, 2011, Qiu, Liyan; Dhe-Paganon, Sirano

Structural consequences of mono-glucosylation of Ha-Ras by Clostridium sordellii lethal toxin 1 1 Edited by R. Huber
score: 3.7345939, Journal of Molecular Biology, 2000, Vetter, Ingrid R et. al.

ZZ Made EZ: Influence of Inhibitor Configuration on Enzyme Selectivity
score: 3.7299199, Journal of Molecular Biology, 2003, Rauh, Daniel et. al.

Multiple Conformations of the FliG C-Terminal Domain Provide Insight into Flagellar Motor Switching
score: 3.7288355, Structure, 2012, Lam, Kwok-Ho et. al.

Solution structure of the strawberry allergen Fra a 1
score: 3.7272122, Bioscience Reports, 2012, Seutter von Loetzen, Christian et. al.

The Critical Role of Hinge-Region Expulsion in the Induced-Fit Heparin Binding Mechanism of Antithrombin
score: 3.7243544, Journal of Molecular Biology, 2009, Langdown, Jonathan et. al.

Structure-based design of peptide presentation on a viral surface: the crystal structure of a plant/animal virus chimera at 2.8 å resolution
score: 3.7234853, Folding and Design, 1996, Lin, Tianwei et. al.

Structure and immunomodulatory property relationship in NapA of Borrelia burgdorferi
score: 3.7231211, BBA - Proteins and Proteomics, 2010, Codolo, Gaia et. al.

The Crystal Structure of the Intact E. coli RelBE Toxin-Antitoxin Complex Provides the Structural Basis for Conditional Cooperativity
score: 3.7228165, Structure(London, England:1993), 2012, Bøggild, Andreas et. al.

Refined solution structure and backbone dynamics of the archaeal MC1 protein.
score: 3.7212509, The FEBS journal, 2010, Paquet, Françoise et. al.

Crystal structure of the C-terminal region of human p97/DAP5.
score: 3.7206718, Proteins, 2010, Fan, Shilong; Jia, Min-Ze; Gong, Weimin

Structural and functional characterization of CFE88: evidence that a conserved and essential bacterial protein is a methyltransferase.
score: 3.7182559, Protein science : a publication of the Protein Society, 2005, Constantine, Keith L et. al.

Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS).
score: 3.7147117, Proceedings of the National Academy of Sciences of the United States of America, 2012, Zhang, Zi Chao; Chook, Yuh Min

The X-ray crystal structure of a pseudoazurin from Sinorhizobium meliloti
score: 3.71402, Journal of Inorganic Biochemistry, 2012, Laming, Elise M. et. al.

The X-ray crystal structure of a pseudoazurin from Sinorhizobium meliloti
score: 3.71402, Journal of Inorganic Biochemistry, 2012, Laming, Elise M. et. al.

Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway
score: 3.7117068, Archives of Biochemistry and Biophysics, 2012, Lim, Young-Ran et. al.

The X-ray crystal structure of a pseudoazurin from Sinorhizobium meliloti
score: 3.7103809, Journal of Inorganic Biochemistry, 2012, Laming, Elise M. et. al.

Functions, structures and Triton X-100 effect for the catalytic subunits of heterodimeric phospholipases A 2 from Vipera nikolskii venom
score: 3.7095493, Toxicon, 2009, Gao, Wei et. al.

Solution Structure of the Mycobacterium tuberculosis EsxG·EsxH Complex
score: 3.7017914, The Journal of Biological Chemistry, 2011, Ilghari, Dariush et. al.

Identification of the Archaeoglobus fulgidus endonuclease III DNA interaction surface using heteronuclear NMR methods
score: 3.7014638, Structure, 1999, Shekhtman, Alexander et. al.

Structure and function of multiple Ca2+-binding sites in a K+ channel regulator of K+ conductance (RCK) domain.
score: 3.7014515, Proceedings of the National Academy of Sciences of the United States of America, 2011, Pau, Victor P T et. al.

Donor strand exchange and conformational changes during E. coli fimbrial formation
score: 3.7010904, Journal of Structural Biology, 2010, Le Trong, Isolde et. al.

Crystal Structure of the DNA-Binding Domain of the Epstein–Barr Virus Origin-Binding Protein, EBNA1, Bound to DNA
score: 3.7010291, Cell, 1996, Bochkarev, Alexey et. al.

Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase.
score: 3.6963281, Proceedings of the National Academy of Sciences of the United States of America, 2011, Cardinale, Daniela et. al.

Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography.
score: 3.6952324, Proceedings of the National Academy of Sciences of the United States of America, 2012, Mandal, Kalyaneswar et. al.

Quality assessment of NMR structures: a statistical survey 1 1 Edited by P. E. Wright
score: 3.6934337, Journal of Molecular Biology, 1998, Doreleijers, Jurgen F. et. al.

Structure of the Rigor Actin-Tropomyosin-Myosin Complex
score: 3.6920222, Cell, 2012, Behrmann, Elmar et. al.

The 15-K neutron structure of saccharide-free concanavalin A.
score: 3.69178, Proceedings of the National Academy of Sciences of the United States of America, 2004, Blakeley, M P; Kalb, A J; Helliwell, J R; Myles, D A A

A synergistic approach to protein crystallization: combination of a fixed-arm carrier with surface entropy reduction.
score: 3.6897099, Protein science : a publication of the Protein Society, 2010, Moon, Andrea F et. al.

Molecular, crystal and solution structure of a β-cyclodextrin complex with the bromide salt of 2-(3-dimethylaminopropyl)tricyclo[3.3.1.1 3,7]decan-2-ol, a potent antimicrobial drug
score: 3.6891115, Carbohydrate Research, 1999, Perrakis, Anastassis et. al.

Blind Testing of Routine, Fully Automated Determination of Protein Structures from NMR Data
score: 3.6880866, Structure, 2012, Rosato, Antonio et. al.

A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication.
score: 3.6839288, Proceedings of the National Academy of Sciences of the United States of America, 2008, Ratia, Kiira et. al.

Structural basis for a ribofuranosyl binding protein: insights into the furanose specific transport.
score: 3.6835347, Proteins, 2011, Bagaria, Ashima et. al.

Macrocyclic statine-based inhibitors of BACE-1.
score: 3.680733, Chembiochem : a European journal of chemical biology, 2007, Barazza, Alessandra et. al.

Crystallographic Refinement by Knowledge-Based Exploration of Complex Energy Landscapes
score: 3.6778735, Structure, 2005, DePristo, Mark A. et. al.

Concerted bifunctionality of the dCTP deaminase-dUTPase from Methanocaldococcus jannaschii: A structural and pre-steady state kinetic analysis
score: 3.6767608, Archives of Biochemistry and Biophysics, 2009, Siggaard, Julie H.B. et. al.

Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine
score: 3.6764307, DNA Repair, 2012, Duclos, Stéphanie et. al.

Displacement of disordered water molecules from hydrophobic pocket creates enthalpic signature: Binding of phosphonamidate to the S 1'-pocket of thermolysin
score: 3.6761719, BBA - General Subjects, 2010, Englert, L. et. al.

Relation between sequence and structure of HIV-1 protease inhibitor complexes: a model system for the analysis of protein flexibility 1 1 Edited by R. Huber
score: 3.6743258, Journal of Molecular Biology, 2002, Zoete, V.; Michielin, O.; Karplus, M.

Crystal structure of the human IgG4 CH3 dimer reveals the role of Arg409 in the mechanism of Fab-arm exchange
score: 3.6725213, Molecular Immunology, 2013, Davies, Anna M. et. al.

Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis
score: 3.6711214, Nucleic Acids Research, 2012, Bolla, Jani Reddy et. al.

Improving the accuracy of macromolecular structure refinement at 7 Å resolution
score: 3.6678736, Structure, 2012, Brunger, Axel T. et. al.

Structural evidence for conformational changes of Delta class glutathione transferases after ligand binding
score: 3.6678464, Archives of Biochemistry and Biophysics, 2012, Wongsantichon, Jantana et. al.

An Inserted α/β Subdomain Shapes the Catalytic Pocket of Lactobacillus johnsonii Cinnamoyl Esterase
score: 3.6653494, PLoS ONE, 2011, Lai, Kin-Kwan et. al.

Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5
score: 3.6640056, Cell, 2013, Wu, Bin et. al.

Structural basis of transcriptional pausing in bacteria
score: 3.6634255, Cell, 2013, Weixlbaumer, Albert et. al.

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives
score: 3.6622206, Bioorganic & Medicinal Chemistry, 2012, Hirose, Masaaki et. al.

Photosystem I of Synechococcus elongatus at 4 Å resolution: comprehensive structure analysis 1 1 Edited by R. Huber
score: 3.6617541, Journal of Molecular Biology, 1997, Schubert, Wolf-Dieter et. al.

Structure of a knockout mutant of influenza virus M1 protein that has altered activities in membrane binding, oligomerisation and binding to NEP (NS2)
score: 3.6609804, Virus Research, 2004, Arzt, Steffi et. al.

Structural basis for protein phosphatase 1 regulation and specificity.
score: 3.6597228, The FEBS journal, 2012, Peti, Wolfgang; Nairn, Angus C; Page, Rebecca

Single-stranded DNA–protein interactions in canine parvovirus
score: 3.6585654, Structure, 1995, Chapman, Michael S; Rossmann, Michael G

Stabilizing Ionic Interactions in a Full-consensus Ankyrin Repeat Protein
score: 3.6563303, Journal of Molecular Biology, 2008, Merz, Tobias et. al.

High-pressure-induced water penetration into 3-­isopropylmalate dehydrogenase
score: 3.6560367, Acta Crystallographica Section D: Biological Crystallography, 2012, Nagae, Takayuki et. al.

Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures.
score: 3.6533076, The FEBS journal, 2008, Wlodawer, Alexander et. al.

Structural Basis of Rnd1 Binding to Plexin Rho GTPase Binding Domains (RBDs) *
score: 3.6501144, The Journal of Biological Chemistry, 2011, Wang, Hui et. al.

Transient structure and SH3 interaction sites in an intrinsically disordered fragment of the hepatitis C virus protein NS5A
score: 3.6474272, Journal of Molecular Biology, 2012, Feuerstein, Sophie et. al.

First-time crystallization and preliminary X-ray crystallographic analysis of a bacterial-archaeal type UMP kinase, a key enzyme in microbial pyrimidine biosynthesis
score: 3.6460909, BBA - Proteins and Proteomics, 2005, Marco-Marín, Clara et. al.

Molecular recognition mechanisms of thrombin.
score: 3.6438946, Journal of thrombosis and haemostasis : JTH, 2005, Huntington, J A

Crystallographic structure of PNP from Mycobacterium tuberculosis at 1.9 Å resolution
score: 3.6430967, Biochemical and Biophysical Research Communications, 2004, Nolasco, Diego O. et. al.

Phosphorylation-dependent structure of ATF4 peptides derived from a human ATF4 protein, a member of the family of transcription factors
score: 3.6408101, Peptides, 2007, Pons, Julien et. al.

The structure of an unconventional HD-GYP protein from Bdellovibrio reveals the roles of conserved residues in this class of cyclic-di-GMP phosphodiesterases.
score: 3.6407241, mBio, 2011, Lovering, Andrew L et. al.

Crystal Structure of the Ca V2 IQ Domain in Complex with Ca 2+/Calmodulin: High-Resolution Mechanistic Implications for Channel Regulation by Ca 2+
score: 3.6392291, Structure, 2008, Mori, Masayuki X. et. al.

Increased Backbone Mobility in β-Barrel Enhances Entropy Gain Driving Binding of N-TIMP-1 to MMP-3
score: 3.6391014, Journal of Molecular Biology, 2003, Arumugam, S. et. al.

Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: A comparison of the X-ray crystal structures of all human 14-3-3 isoforms
score: 3.6384543, Seminars in Cancer Biology, 2006, Gardino, Alexandra K. et. al.

Disease Mutations in the Ryanodine Receptor Central Region: Crystal Structures of a Phosphorylation Hot Spot Domain
score: 3.6382804, Structure, 2012, Yuchi, Zhiguang; Lau, Kelvin; Van Petegem, Filip

Disease Mutations in the Ryanodine Receptor Central Region: Crystal Structures of a Phosphorylation Hot Spot Domain
score: 3.6382804, Structure, 2012, Yuchi, Zhiguang; Lau, Kelvin; Van Petegem, Filip

Human RegIV Protein Adopts a Typical C-Type Lectin Fold but Binds Mannan with Two Calcium-Independent Sites
score: 3.6362518, Journal of Molecular Biology, 2010, Ho, Meng-Ru et. al.

Structure-oriented methods for protein NMR data analysis
score: 3.6357738, Progress in Nuclear Magnetic Resonance Spectroscopy, 2010, Bermejo, Guillermo A.; Llinás, Miguel

Structural basis of activity and subunit recognition in G protein heterotrimers
score: 3.6342278, Structure, 1998, Wall, Mark A; Posner, Bruce A; Sprang, Stephen R

Expression, purification, and crystallization of endopolygalacturonase from a pathogenic fungus, Stereum purpureum, in Escherichia coli
score: 3.6319508, Protein Expression and Purification, 2005, Shimizu, Tetsuya et. al.

Fused bicyclic heteroarylpiperazine-substituted l-prolylthiazolidines as highly potent DPP-4 inhibitors lacking the electrophilic nitrile group
score: 3.631334, Bioorganic & Medicinal Chemistry, 2012, Yoshida, Tomohiro et. al.

Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states
score: 3.6281864, Chemistry & Biology, 1995, Rosenzweig, Amy C. et. al.

A single amino acid change in the binding pocket alters specificity of an anti-integrin antibody AP7.4 as revealed by its crystal structure
score: 3.6263041, Blood Cells, Molecules and Diseases, 2004, Vasudevan, Sona et. al.

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2
score: 3.6253675, Nature, 2012, Armstrong, Anthony A.; Mohideen, Firaz; Lima, Christopher D.

Crystal structure of LeuD from Methanococcus jannaschii
score: 3.6253585, Biochemical and Biophysical Research Communications, 2012, Lee, Eun Hye; Cho, Yong Wook; Hwang, Kwang Yeon

Pound-Wise but Penny-Foolish
score: 3.6234356, Structure, 2003, Kleywegt, Gerard J. et. al.

Structural and biochemical studies of the open state of Lys48-linked diubiquitin
score: 3.622471, BBA - Molecular Cell Research, 2012, Lai, Ming-Yih et. al.

Structural and biochemical studies of the open state of Lys48-linked diubiquitin
score: 3.622471, BBA - Molecular Cell Research, 2012, Lai, Ming-Yih et. al.

Structural and biochemical studies of the open state of Lys48-linked diubiquitin
score: 3.622471, BBA - Molecular Cell Research, 2012, Lai, Ming-Yih et. al.

Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor
score: 3.6216349, Journal of Structural Biology, 2012, García-Fernández, Rossana et. al.

Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor
score: 3.6216349, Journal of Structural Biology, 2012, García-Fernández, Rossana et. al.

Structural basis for activation of fibroblast growth factor signaling by sucrose octasulfate.
score: 3.6194937, Molecular and cellular biology, 2002, Yeh, Brian K et. al.

The Affinity of Ets-1 for DNA is Modulated by Phosphorylation Through Transient Interactions of an Unstructured Region
score: 3.6193918, Journal of Molecular Biology, 2008, Lee, Gregory M. et. al.

Structural basis for the binding of high affinity phosphopeptides to Stat3.
score: 3.6164051, Biopolymers, 2008, McMurray, John S

Refined Crystal Structure of the Catalytic Domain of Dihydrolipoyl Transacetylase (E2p) from Azotobacter vinelandii at 2·6 Å Resolution
score: 3.6162577, Journal of Molecular Biology, 1993, Mattevi, Andrea et. al.

Preparation and Characterization of Bacterial Protein Complexes for Structural Analysis
score: 3.6161122, Advances in Protein Chemistry and Structural Biology, 2009, Matte, Allan et. al.

Preparation and Characterization of Bacterial Protein Complexes for Structural Analysis
score: 3.6161122, Advances in Protein Chemistry and Structural Biology, 2009, Matte, Allan et. al.

Preparation and Characterization of Bacterial Protein Complexes for Structural Analysis
score: 3.6161122, Advances in Protein Chemistry and Structural Biology, 2009, Matte, Allan et. al.

Structural and Mechanistic Studies on γ-Butyrobetaine Hydroxylase
score: 3.6149454, Chemistry & Biology, 2010, Leung, Ivanhoe K.H. et. al.

Crystal structure of the GlnZ-DraG complex reveals a different form of PII-target interaction.
score: 3.6124753, Proceedings of the National Academy of Sciences of the United States of America, 2011, Rajendran, Chitra et. al.

Comparative structural analysis by [ 1H, 31P]-NMR and restrained molecular dynamics of two DNA hairpins from a strong DNA topoisomerase II cleavage site 1 1 Edited by I. Tinoco
score: 3.6122099, Journal of Molecular Biology, 1998, Mauffret, O et. al.

Collagen adhesin - nanoparticle interaction impairs adhesin's ligand binding mechanism
score: 3.6115379, BBA - General Subjects, 2012, Devi, Aribam Swarmistha et. al.

Solution Structure of TT30, a Novel Complement Therapeutic Agent, Provides Insight into Its Joint Binding to Complement C3b and C3d
score: 3.6101988, Journal of Molecular Biology, 2012, Li, Keying et. al.

Structural characterization reveals that a PilZ domain protein undergoes substantial conformational change upon binding to cyclic dimeric guanosine monophosphate.
score: 3.6080102, Protein science : a publication of the Protein Society, 2011, Shin, Jae-Sun et. al.

High resolution structure of streptavidin in complex with a novel high affinity peptide tag mimicking the biotin binding motif.
score: 3.6058371, Proteins, 2007, Perbandt, M et. al.

Sub-Ångstrom resolution enzyme X-ray structures: is seeing believing?
score: 3.6051707, Current Opinion in Structural Biology, 2003, Vrielink, Alice; Sampson, Nicole

Proteins
score: 3.6039803, Current Opinion in Structural Biology, 1995,

The Structure of Neuroglobin at High Xe and Kr Pressure Reveals Partial Conservation of Globin Internal Cavities
score: 3.603245, Biophysical Journal, 2009, Moschetti, Tommaso et. al.

Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A₂ class.
score: 3.6024301, Proteins, 2011, dos Santos, Juliana I et. al.

Structural basis of tRNA agmatinylation essential for AUA codon decoding.
score: 3.6018169, Nature structural & molecular biology, 2011, Osawa, Takuo et. al.

Structure and Dynamics of the ATP-Bound Open Conformation of Hsp70 Chaperones
score: 3.5987094, Molecular Cell, 2012, Kityk, Roman et. al.

Structure and Dynamics of the ATP-Bound Open Conformation of Hsp70 Chaperones
score: 3.5987094, Molecular Cell, 2012, Kityk, Roman et. al.

Macrocyclic inhibitors of the NS3 protease as potential therapeutic agents of hepatitis C virus infection.
score: 3.5971791, Angewandte Chemie (International ed. in English), 2003, Tsantrizos, Youla S et. al.

Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A.
score: 3.5968295, Proceedings of the National Academy of Sciences of the United States of America, 2005, Scott, Anna et. al.

Structure of a hexameric form of RadA recombinase from Methanococcus voltae
score: 3.5955016, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2012, Du, Liqin; Luo, Yu

Crystal structure of the FAD-containing fragment of corn nitrate reductase at 2.5å resolution: relationship to other flavoprotein reductases
score: 3.594224, Structure, 1994, Lu, Guoguang et. al.

Four generations of transition-state analogues for human purine nucleoside phosphorylase.
score: 3.5921091, Proceedings of the National Academy of Sciences of the United States of America, 2010, Ho, Meng-Chiao et. al.

Structural and biochemical studies of the open state of Lys48-linked diubiquitin
score: 3.5904201, BBA - Molecular Cell Research, 2012, Lai, Ming-Yih et. al.

Structural and functional characterization of a 5,10-methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087).
score: 3.5888678, Proteins, 2005, Chen, Shengfeng et. al.

Structural and Functional Analysis of the ARF1–ARFGAP Complex Reveals a Role for Coatomer in GTP Hydrolysis
score: 3.5877565, Cell, 1999, Goldberg, Jonathan

Structure-based development of bacterial nitroreductase against nitrobenzodiazepine-induced hypnosis
score: 3.5831129, Biochemical Pharmacology, 2012, LinWu, Shiuan-Woei et. al.

Structure-based development of bacterial nitroreductase against nitrobenzodiazepine-induced hypnosis
score: 3.5831129, Biochemical Pharmacology, 2012, LinWu, Shiuan-Woei et. al.

Quaternary assembly and crystal structure of GDP- d-mannose 4,6 dehydratase from Paramecium bursaria Chlorella virus
score: 3.5808463, Biochemical and Biophysical Research Communications, 2006, Rosano, Camillo et. al.

Cyclic-AMP regulation of protein lysine acetylation in Mycobacterium tuberculosis
score: 3.5788042, Nature structural & molecular biology, 2012, Lee, Ho Jun et. al.

Structure of crimean-congo hemorrhagic Fever virus nucleoprotein: superhelical homo-oligomers and the role of caspase-3 cleavage.
score: 3.5787916, Journal of virology, 2012, Wang, Yi et. al.

The Myosin Chaperone UNC-45 Is Organized in Tandem Modules to Support Myofilament Formation in C. elegans
score: 3.5787133, Cell, 2013, Gazda, Linn et. al.

Interaction of the IκBα C-terminal PEST Sequence with NF-κB: Insights into the Inhibition of NF-κB DNA Binding by IκBα
score: 3.576659, Journal of Molecular Biology, 2009, Sue, Shih-Che; Dyson, H. Jane

High resolution structure of an oligomeric eye lens β-crystallin
score: 3.5747593, Journal of Molecular Biology, 1991, Lapatto, R. et. al.

Crystal structure of rat trypsin-S195C at −150 °C
score: 3.5738417, Journal of Molecular Biology, 1991, Wilke, Marjorie E. et. al.

Structure of the histidine-containing phosphocarrier protein HPr from Bacillus subtilis at 2.0-A resolution.
score: 3.5687047, Proceedings of the National Academy of Sciences of the United States of America, 1992, Herzberg, O et. al.

The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA
score: 3.5684399, Journal of Molecular Biology, 2012, Lee, Jun Hyuck et. al.

Crystal structure analysis of the translation factor RF3 (release factor 3)
score: 3.5680146, FEBS Letters, 2012, Kihira, Kiyohito et. al.

Crystal structure analysis of the translation factor RF3 (release factor 3)
score: 3.5680146, FEBS Letters, 2012, Kihira, Kiyohito et. al.

Allophycocyanin and phycocyanin crystal structures reveal facets of phycobilisome assembly
score: 3.5678733, BBA - Bioenergetics, 2013, Marx, Ailie; Adir, Noam

Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain.
score: 3.5643546, Proceedings of the National Academy of Sciences of the United States of America, 2011, Wei, Zhiyi; Yan, Jing; Lu, Qing; Pan, Lifeng; Zhang, Mingjie

Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity.
score: 3.5633772, Protein science : a publication of the Protein Society, 2001, Li, Y; Waksman, G

Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme
score: 3.5618706, Nucleic Acids Research, 2012, Benjdia, Alhosna et. al.

Proline Isomerization Preorganizes the Itk SH2 Domain for Binding to the Itk SH3 Domain
score: 3.5591958, Journal of Molecular Biology, 2009, Severin, Andrew et. al.

Structure of the human activating natural cytotoxicity receptor NKp30 bound to its tumor cell ligand B7-H6
score: 3.5588082, The Journal of Experimental Medicine, 2011, Li, Yili; Wang, Qian; Mariuzza, Roy A.

Crystallization and preliminary X-ray diffraction analysis of importin-α complexed with NLS peptidomimetics
score: 3.5576457, BBA - Proteins and Proteomics, 2005, Fontes, Marcos R.M. et. al.

Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme’s active site closure
score: 3.5499276, BMC Structural Biology, 2012, Park, Jaeok et. al.

Structural Basis of the PNRC2-Mediated Link between mRNA Surveillance and Decapping
score: 3.5477984, Structure, 2012, Lai, Tingfeng et. al.

Structural Basis of the PNRC2-Mediated Link between mRNA Surveillance and Decapping
score: 3.5477984, Structure, 2012, Lai, Tingfeng et. al.

Structural studies on cytosolic domain of magnesium transporter MgtE from Enterococcus faecalis.
score: 3.5472768, Proteins, 2010, Ragumani, Sugadev et. al.

Solution structure of a DNA double helix incorporating four consecutive non-Watson-Crick base-pairs 1 1 Edited by I. Tinoco
score: 3.5471762, Journal of Molecular Biology, 2001, Chou, Shan-Ho; Chin, Ko-Hsin

A common channel-forming motif in evolutionarily distant porins
score: 3.5471575, Journal of Structural Biology, 1991, Pauptit, Richard A. et. al.

NMR Studies of the Backbone Flexibility and Structure of Human Growth Hormone: A Comparison of High and Low pH Conformations
score: 3.5444674, Journal of Molecular Biology, 2002, Kasimova, Marina R et. al.

Structure-based design of achiral, nonpeptidic hydroxybenzamide as a novel P2/P2′ replacement for the symmetry-based HIV protease inhibitors
score: 3.5442297, Bioorganic & Medicinal Chemistry, 1996, Randad, Ramnarayan S. et. al.

Isolation, crystallization, crystal structure analysis and refinement of B-phycoerythrin from the red alga Porphyridium sordidum at 2·2 Å resolution
score: 3.5431903, Journal of Molecular Biology, 1992, Ficner, Ralf et. al.

A Molecular Mechanism of Bacterial Flagellar Motor Switching
score: 3.5431375, Journal of Molecular Biology, 2009, Dyer, Collin M. et. al.

The peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
score: 3.5383794, Journal of immunology (Baltimore, Md. : 1950), 2012, Mage, Michael G et. al.

Thermotoga maritima IscU. Structural Characterization and Dynamics of a New Class of Metallochaperone
score: 3.5375557, Journal of Molecular Biology, 2003, Bertini, Ivano et. al.

Crystal structure of human transgelin
score: 3.536861, Journal of Structural Biology, 2008, Li, Ming et. al.

Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein
score: 3.5367437, Cell, 2012, Osmundson, Joseph et. al.

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1
score: 3.5334681, Nature structural & molecular biology, 2010, Chang, Jeong Ho et. al.

GroEL recognises sequential and non-sequential linear structural motifs compatible with extended β-strands and α-helices 1 1 Edited by J. Karn
score: 3.5328633, Journal of Molecular Biology, 1999, Chatellier, Jean; Buckle, Ashley M; Fersht, Alan R

Mechanistic Insights into the Activation of Rad51-Mediated Strand Exchange from the Structure of a Recombination Activator, the Swi5-Sfr1 Complex
score: 3.5290793, Structure, 2012, Kuwabara, Naoyuki et. al.

Site-directed Mutagenesis of Escherichia coli Acetylglutamate Kinase and Aspartokinase III Probes the Catalytic and Substrate-binding Mechanisms of these Amino Acid Kinase Family Enzymes and Allows Three-dimensional Modelling of Aspartokinase
score: 3.5275752, Journal of Molecular Biology, 2003, Marco-Marı́n, Clara et. al.

Structure-Based Development of Small Molecule PFKFB3 Inhibitors: A Framework for Potential Cancer Therapeutic Agents Targeting the Warburg Effect
score: 3.5241764, PLoS ONE, 2011, Seo, Minsuh et. al.

Prion Protein mPrP[F175A](121–231): Structure and Stability in Solution
score: 3.5227116, Journal of Molecular Biology, 2012, Christen, Barbara et. al.

Prion Protein mPrP[F175A](121–231): Structure and Stability in Solution
score: 3.5227116, Journal of Molecular Biology, 2012, Christen, Barbara et. al.

Structure of the Essential MTERF4:NSUN4 Protein Complex Reveals How an MTERF Protein Collaborates to Facilitate rRNA Modification
score: 3.5203889, Structure, 2012, Yakubovskaya, Elena et. al.

Structure of the Essential MTERF4:NSUN4 Protein Complex Reveals How an MTERF Protein Collaborates to Facilitate rRNA Modification
score: 3.5203889, Structure, 2012, Yakubovskaya, Elena et. al.

Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation
score: 3.5188559, Structure, 2012, Ferrage, Fabien et. al.

Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation
score: 3.5188559, Structure, 2012, Ferrage, Fabien et. al.

Structure of the human kappa opioid receptor in complex with JDTic
score: 3.516596, Nature, 2012, Wu, Huixian et. al.

New general approach for determining the solution structure of a ligand bound weakly to a receptor: structure of a fibrinogen Aalpha-like peptide bound to thrombin (S195A) obtained using NOE distance constraints and an ECEPP/3 flexible docking program.
score: 3.5153684, Proteins, 1999, Maurer, M C et. al.

NMR studies of the fifth transmembrane segment of Na +,K +-ATPase reveals a non-helical ion-binding region
score: 3.5152366, FEBS Letters, 2006, Underhaug, Jarl et. al.

Life in the fast lane for protein crystallization and X-ray crystallography
score: 3.5136963, Progress in Biophysics and Molecular Biology, 2005, Pusey, Marc L. et. al.

Conformational Variability of Solution Nucelar Magnetic Resonance Structures
score: 3.5135774, Journal of Molecular Biology, 1995, Bonvin, Alexandre M.J.J.; Brünger, Axel T.

Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain
score: 3.5110266, Journal of Molecular Biology, 2012, Coyne, H. Jerome et. al.

Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain
score: 3.5110266, Journal of Molecular Biology, 2012, Coyne, H. Jerome et. al.

Activity of the MAP kinase ERK2 is controlled by a flexible surface loop
score: 3.5109444, Structure, 1995, Zhang, Jiandong et. al.

High-Resolution 3D Structure Determination of Kaliotoxin by Solid-State NMR Spectroscopy
score: 3.5094634, PLoS ONE, 2008, Korukottu, Jegannath et. al.

Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses
score: 3.5086756, Cell, 2012, Dong, Na et. al.

Structure of the Central Hub of Bacteriophage Mu Baseplate Determined by X-ray Crystallography of gp44
score: 3.5034499, Journal of Molecular Biology, 2005, Kondou, Youhei et. al.

Novel Binding of the Mitotic Regulator TPX2 (Target Protein for Xenopus Kinesin-like Protein 2) to Importin-α *
score: 3.5029906, The Journal of Biological Chemistry, 2010, Giesecke, Astrid; Stewart, Murray

High-throughput crystallization and structure determination in drug discovery
score: 3.5027359, Drug Discovery Today, 2002, Stewart, Lance; Clark, Robin; Behnke, Craig

X-ray structure of human aromatase reveals an androgen-specific active site
score: 3.499978, Journal of Steroid Biochemistry and Molecular Biology, 2010, Ghosh, Debashis et. al.

Metal Binding Properties of Escherichia coli YjiA, a Member of the Metal Homeostasis-Associated COG0523 Familyof GTPases
score: 3.4995326, Biochemistry, 2013, Sydor, Andrew M. et. al.

A New Generation of Crystallographic Validation Tools for the Protein Data Bank
score: 3.4936546, Structure(London, England:1993), 2011, Read, Randy J. et. al.

Solution structure of the antitermination protein NusB of Escherichia coli: a novel all-helical fold for an RNA-binding protein.
score: 3.4914962, The EMBO journal, 1998, Huenges, M et. al.

The role of high-resolution structural studies in the development of commercial enzymes
score: 3.4911357, Current Opinion in Biotechnology, 1999, Bott, Richard; Boelens, Rolf

Conformations of the third hypervariable region in the VH domain of immunoglobulins 1 1 Edited by I. A. Wilson
score: 3.4892095, Journal of Molecular Biology, 1998, Morea, Veronica et. al.

Kinetic and Structural Characterisation of Escherichia coli Nitroreductase Mutants Showing Improved Efficacy for the Prodrug Substrate CB1954
score: 3.48813, Journal of Molecular Biology, 2007, Race, Paul R. et. al.

Crystal structure of chondroitin polymerase from Escherichia coli K4
score: 3.4879332, Biochemical and Biophysical Research Communications, 2009, Osawa, Takuo et. al.

N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity.
score: 3.48384, Antimicrobial agents and chemotherapy, 2002, Hackbarth, Corinne J et. al.

Intermediate Filament Protein Structure Determination
score: 3.4811217, Methods in Cell Biology, 2004, Strelkov, Sergei V. et. al.

DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation
score: 3.4808959, Cell Reports, 2012, Chen, Yongheng et. al.

DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation
score: 3.4808959, Cell Reports, 2012, Chen, Yongheng et. al.

The 70-kDa heat shock protein chaperone nucleotide-binding domain in solution unveiled as a molecular machine that can reorient its functional subdomains.
score: 3.4797438, Proceedings of the National Academy of Sciences of the United States of America, 2004, Zhang, Yongbo; Zuiderweg, Erik R P

Molecular basis of α1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer.
score: 3.4767339, EMBO reports, 2011, Yamasaki, Masayuki et. al.

Crystal and solution structures disclose a putative transient state of mitogen-activated protein kinase kinase 4
score: 3.4754298, Biochemical and Biophysical Research Communications, 2012, Matsumoto, Takashi et. al.

Critical assessment of quantum mechanics based energy restraints in protein crystal structure refinement.
score: 3.4749795, Protein science : a publication of the Protein Society, 2006, Yu, Ning et. al.

The C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rate.
score: 3.4742419, Nature communications, 2012, Irie, Katsumasa; Shimomura, Takushi; Fujiyoshi, Yoshinori

Solution structure of the bacterial chemotaxis adaptor protein CheW from Escherichia coli
score: 3.4740123, Biochemical and Biophysical Research Communications, 2007, Li, You; Hu, Yunfei; Fu, Wenyu; Xia, Bin; Jin, Changwen

Vanadium containing bromoperoxidase – Insights into the enzymatic mechanism using X-ray crystallography
score: 3.4727798, Journal of Inorganic Biochemistry, 2009, Littlechild, Jennifer et. al.

Structure of a fucose transporter in an outward-open conformation.
score: 3.4726228, Nature, 2010, Dang, Shangyu et. al.

The crystal structure of glucose dehydrogenase from Thermoplasma acidophilum
score: 3.4671659, Structure, 1994, John, Jamie et. al.

Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins And Its Mode of Sphingomyelin Recognition
score: 3.4671167, Structure(London, England:1993), 2012, De Colibus, Luigi et. al.

Novel structural features of xylanase A1 from Paenibacillus sp. JDR-2
score: 3.4623148, Journal of Structural Biology, 2012, St. John, Franz J.; Preston, James F.; Pozharski, Edwin

The restricted binding repertoire of Bcl-B leaves Bim as the universal BH3-only prosurvival Bcl-2 protein antagonist
score: 3.4605098, Cell Death & Disease, 2012, Rautureau, G J P et. al.

Structure/Function Implications in a Dynamic Complex of the Intrinsically Disordered Sic1 with the Cdc4 Subunit of an SCF Ubiquitin Ligase
score: 3.4601334, Structure, 2010, Mittag, Tanja et. al.

Two lutein molecules in LHCII have different conformations and functions: Insights into the molecular mechanism of thermal dissipation in plants
score: 3.4594253, Biochemical and Biophysical Research Communications, 2007, Yan, Hanchi et. al.

NMR spectroscopy of G-quadruplexes
score: 3.4590457, Methods, 2012, Adrian, Michael; Heddi, Brahim; Phan, Anh Tuân

Multistart simulated annealing refinement of the crystal structure of the 70S ribosome.
score: 3.4589669, Proceedings of the National Academy of Sciences of the United States of America, 2009, Korostelev, Andrei; Laurberg, Martin; Noller, Harry F

A Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor Suppressors
score: 3.4578728, Cell, 2012, Ou, Horng D. et. al.

NMR structural characterization of the penta-peptide calpain inhibitor
score: 3.455777, FEBS Letters, 2009, Deshmukh, Lalit et. al.

Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology
score: 3.4537712, Nucleic Acids Research, 2013, Slaymaker, Ian M. et. al.

Crystal structure of a chimera of human and Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferases provides insights into oligomerization.
score: 3.4530842, Proteins, 2008, Gayathri, P et. al.

Refined crystal structure of Cd, Zn metallothionein at 2.0Åresolution
score: 3.4525469, Journal of Molecular Biology, 1991, Robbins, A.H. et. al.

Altering the RNA-binding Mode of the U1A RBD1 Protein
score: 3.4520317, Journal of Molecular Biology, 2004, Showalter, Scott A; Hall, Kathleen B

Crystal structure of the reduced form of p-hydroxybenzoate hydroxylase refined at 2.3 A resolution.
score: 3.4514452, Proteins, 1992, Schreuder, H A et. al.

Bioincorporation of telluromethionine into proteins: a promising new approach for X-ray structure analysis of proteins 1 1 Edited by K. Nagai
score: 3.4510492, Journal of Molecular Biology, 1997, Budisa, Nediljko et. al.

Crystal structure of PqqC from Klebsiella pneumoniae at 2.1 A resolution.
score: 3.448281, Proteins, 2004, Schwarzenbacher, Robert et. al.

The Mechanism of ATP-Dependent Primer-Template Recognition by a Clamp Loader Complex
score: 3.4455832, Cell, 2009, Simonetta, Kyle R. et. al.

The AEROPATH project targeting Pseudomonas aeruginosa : crystallographic studies for assessment of potential targets in early-stage drug discovery
score: 3.4446163, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2012, Moynie, Lucille et. al.

Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix , a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop
score: 3.4435647, Nucleic Acids Research, 2011, Hirata, Akira; Kitajima, Tsubasa; Hori, Hiroyuki

Crystal structure of Pseudomonas fluorescens mannitol 2-dehydrogenase: evidence for a very divergent long-chain dehydrogenase family
score: 3.4432633, Chemico-Biological Interactions, 2003, Kavanagh, Kathryn L et. al.

Differential Responses of the Backbone and Side-Chain Conformational Dynamics in FKBP12 upon Binding the Transition-State Analog FK506: Implications for Transition-State Stabilization and Target Protein Recognition
score: 3.4431148, Journal of Molecular Biology, 2009, Brath, Ulrika; Akke, Mikael

A Guided Tour of the Structural Biology of Gaucher Disease: Acid- β -Glucosidase and Saposin C
score: 3.4423295, Enzyme Research, 2011, Lieberman, Raquel L.

Interaction of the C-terminal domain of the E. coli RNA polymerase α subunit with the UP element: recognizing the backbone structure in the minor groove surface 1 1 Edited by R. Ebright
score: 3.4405118, Journal of Molecular Biology, 2001, Yasuno, Kazuhiro et. al.

Automated analysis of NMR assignments and structures for proteins
score: 3.4398303, Current Opinion in Structural Biology, 1999, Moseley, Hunter NB; Montelione, Gaetano T

Structural Basis for Ligand Recognition of Incretin Receptors
score: 3.4391769, Vitamins and Hormones, 2010, Underwood, Christina Rye et. al.

Kringle solution structures via NMR: two-dimensional 1H-NMR analysis of horse plasminogen kringle 4
score: 3.4368033, Chemistry and Physics of Lipids, 1994, Cox, Michel et. al.

Assays for the Determination of Structure and Dynamics of the Interaction of the Chromodomain with Histone Peptides
score: 3.4361022, Methods in Enzymology, 2003, Jacobs, Steven A. et. al.

Three-dimensional structure of the adenine-specific DNA methyltransferase M.Taq I in complex with the cofactor S-adenosylmethionine.
score: 3.4354507, Proceedings of the National Academy of Sciences of the United States of America, 1994, Labahn, J et. al.

Atomic Resolution Crystal Structure of NAD + -Dependent Formate Dehydrogenase from Bacterium Moraxella sp. C-1
score: 3.4334624, Acta Naturae, 2009, Shabalin, I.G.; Polyakov, K.M.; Tishkov, V.I.; Popov, V.O.

Structural evidence for conformational changes of Delta class glutathione transferases after ligand binding
score: 3.4310955, Archives of Biochemistry and Biophysics, 2012, Wongsantichon, Jantana et. al.

Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses.
score: 3.4304744, Journal of virology, 2012, Kim, Yunjeong et. al.

Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate 1 1 Edited by J. Karn
score: 3.4304664, Journal of Molecular Biology, 2002, Scott, John W et. al.

Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain
score: 3.4290439, Journal of Molecular Biology, 2012, Coyne, H. Jerome et. al.

Structural and functional properties of staphylococcal superantigen-like protein 4.
score: 3.4260799, Infection and immunity, 2012, Hermans, Stefan J et. al.

Discovery of a Distinct Superfamily of Kunitz-Type Toxin (KTT) from Tarantulas
score: 3.4252923, PLoS ONE, 2008, Yuan, Chun-Hua et. al.

Relevance of the conserved histidine and asparagine residues in the phosphate-binding loop of the nucleotide binding subunit B of A1AO ATP synthases
score: 3.4201584, Journal of Structural Biology, 2012, Tadwal, Vikeramjeet Singh et. al.

Structural basis for activation of the complement system by component C4 cleavage.
score: 3.4200414, Proceedings of the National Academy of Sciences of the United States of America, 2012, Kidmose, Rune T et. al.

Article
score: 3.4194136, Journal of Molecular Biology, 1994, Kraulis, Per J.

Defining the Intramembrane Binding Mechanism of Sarcolipin to Calcium ATPase Using Solution NMR Spectroscopy
score: 3.4178359, Journal of Molecular Biology, 2006, Buffy, Jarrod J. et. al.

Structural mechanism of C-type inactivation in K(+) channels.
score: 3.4171977, Nature, 2010, Cuello, Luis G et. al.

Structure of the human κ-opioid receptor in complex with JDTic.
score: 3.4160055, Nature, 2012, Wu, Huixian et. al.

Solution structure and thermodynamics of a divalent metal ion binding site in an RNA pseudokno 1 1 Edited by D. E. Draper
score: 3.4136232, Journal of Molecular Biology, 1999, Gonzalez, Ruben L.; Tinoco, Ignacio

Characterizing septum inhibition in Mycobacterium tuberculosis for novel drug discovery
score: 3.412443, Tuberculosis, 2008, Respicio, Laurel et. al.

A novel norindenoisoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complex.
score: 3.4099036, Molecular cancer therapeutics, 2006, Marchand, Christophe et. al.

Ligand-induced Conformational Changes and Conformational Dynamics in the Solution Structure of the Lactose Repressor Protein
score: 3.4090552, Journal of Molecular Biology, 2008, Taraban, Marc et. al.

Lipids in membrane protein structures
score: 3.4086227, BBA - Biomembranes, 2004, Palsdottir, Hildur; Hunte, Carola

Comparison of Entropic Contributions to Binding in a “Hydrophilic” versus “Hydrophobic” Ligand−Protein Interaction
score: 3.40562, Journal of the American Chemical Society, 2010, Syme, Neil R. et. al.

Characterization of Vibrio cholerae Hfq Provides Novel Insights into the Role of the Hfq C-Terminal Region
score: 3.4040793, Journal of Molecular Biology, 2012, Vincent, Helen A. et. al.

Characterization of Vibrio cholerae Hfq Provides Novel Insights into the Role of the Hfq C-Terminal Region
score: 3.4040793, Journal of Molecular Biology, 2012, Vincent, Helen A. et. al.

Characterization of Vibrio cholerae Hfq Provides Novel Insights into the Role of the Hfq C-Terminal Region
score: 3.4040793, Journal of Molecular Biology, 2012, Vincent, Helen A. et. al.

Structure of catalase HPII from Escherichia coli at 1.9 A resolution.
score: 3.4036137, Proteins, 1999, Bravo, J et. al.

Crystal structure of glutathione-independent formaldehyde dehydrogenase
score: 3.4025349, Chemico-Biological Interactions, 2003, Tanaka, Nobutada et. al.

Low-resolution structure refinement in electron microscopy
score: 3.4024831, Journal of Structural Biology, 2003, Chen, James Z. et. al.

The Structure of Fcp1, an Essential RNA Polymerase II CTD Phosphatase
score: 3.4007784, Molecular Cell, 2008, Ghosh, Agnidipta; Shuman, Stewart; Lima, Christopher D.

Type II Natural Killer T cells recognize sulfatide self-antigens using features of both innate-like and conventional T cells
score: 3.4007073, Nature immunology, 2012, Girardi, Enrico et. al.

Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion
score: 3.4002482, Chemistry & Biology, 2012, Bacik, John-Paul et. al.

A single point mutation disrupts the capsid assembly in Sesbania Mosaic Virus resulting in a stable isolated dimer
score: 3.3996629, Virology, 2009, Pappachan, Anju et. al.

Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3.
score: 3.3993481, Molecular and cellular biology, 2011, Gamsjaeger, Roland et. al.

Insights into the mechanism of drug resistance: X-ray structure analysis of multi-drug resistant HIV-1 protease ritonavir complex
score: 3.3984767, Biochemical and Biophysical Research Communications, 2013, Liu, Zhigang et. al.

AcrB et al.: Obstinate contaminants in a picogram scale. One more bottleneck in the membrane protein structure pipeline
score: 3.3962237, Journal of Structural Biology, 2009, Psakis, Georgios; Polaczek, Julia; Essen, Lars-Oliver

Structural Basis of Evasion of Cellular Adaptive Immunity by HIV-1 Nef
score: 3.3960094, Nature structural & molecular biology, 2012, Jia, Xiaofei et. al.

Structural Insight into DFMO Resistant Ornithine Decarboxylase from Entamoeba histolytica : An Inkling to Adaptive Evolution
score: 3.3958672, PLoS ONE, 2013, Preeti, et. al.

Molecular basis for recognition of dilysine trafficking motifs by COPI
score: 3.3955126, Developmental Cell, 2012, Jackson, Lauren P. et. al.

Target Binding to S100B Reduces Dynamic Properties and Increases Ca2+-Binding Affinity for Wild Type and EF-Hand Mutant Proteins
score: 3.3946898, Journal of Molecular Biology, 2012, Liriano, Melissa A. et. al.

Crystallography for protein kinase drug design: PKA and SRC case studies
score: 3.3926224, BBA - Proteins and Proteomics, 2005, Breitenlechner, Christine B. et. al.

HIV‐1 Protease: Structure, Dynamics, and Inhibition
score: 3.3913429, Advances in Pharmacology, 2007, Louis, John M. et. al.

Towards Structural Genomics of RNA: Rapid NMR Resonance Assignment and Simultaneous RNA Tertiary Structure Determination Using Residual Dipolar Couplings
score: 3.3912533, Journal of Molecular Biology, 2002, Al-Hashimi, Hashim M. et. al.

Conformational flexibility of RNA polymerase III during transcriptional elongation.
score: 3.3887078, The EMBO journal, 2010, Fernández-Tornero, Carlos et. al.

Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry
score: 3.3868314, PLoS Pathogens, 2010, Porotto, Matteo et. al.

Comparison of the solution nuclear magnetic resonance and crystal structures of interleukin-8
score: 3.3867559, Journal of Molecular Biology, 1991, Clore, G.Marius; Gronenborn, Angela M.

Structural investigation of the C-terminal catalytic fragment of presenilin 1.
score: 3.3849199, Proceedings of the National Academy of Sciences of the United States of America, 2010, Sobhanifar, Solmaz et. al.

The NMR structure of stomagen reveals the basis of stomatal density regulation by plant peptide hormones.
score: 3.3848736, Nature communications, 2011, Ohki, Shinya; Takeuchi, Makoto; Mori, Masashi

From the Periplasmic Signaling Domain to the Extracellular Face of an Outer Membrane Signal Transducer of Pseudomonas aeruginosa: Crystal Structure of the Ferric Pyoverdine Outer Membrane Receptor
score: 3.3847433, Journal of Molecular Biology, 2007, Wirth, Christophe et. al.

Mutational Analysis Defines the Roles of Conserved Amino Acid Residues in the Predicted Catalytic Pocket of the rRNA:m 6A Methyltransferase ErmC′
score: 3.3785801, Journal of Molecular Biology, 2003, Maravić, Gordana et. al.

Crystal structure of quinol-dependent nitric oxide reductase from Geobacillus stearothermophilus.
score: 3.3771163, Nature structural & molecular biology, 2012, Matsumoto, Yushi et. al.

Dynamic Requirements for a Functional Protein Hinge
score: 3.3769345, Journal of Molecular Biology, 2007, Kempf, James G. et. al.

Structure of the Bone Morphogenetic Protein Receptor ALK2 and Implications for Fibrodysplasia Ossificans Progressiva *
score: 3.3759686, The Journal of Biological Chemistry, 2012, Chaikuad, Apirat et. al.

Location and Flexibility of the Unique C-Terminal Tail of Aquifex aeolicus Co-Chaperonin Protein 10 as Derived by Cryo-Electron Microscopy and Biophysical Techniques
score: 3.3736467, Journal of Molecular Biology, 2008, Chen, Dong-Hua et. al.

Evaluation of Site-Directed Spin Labeling for Characterizing Protein-Ligand Complexes Using Simulated Restraints
score: 3.3727042, Biophysical Journal, 2001, Constantine, Keith L.

The Solution Structure of the N-Terminal Domain of Human Tubulin Binding Cofactor C Reveals a Platform for Tubulin Interaction
score: 3.3713523, PLoS ONE, 2011, Garcia-Mayoral, Mª Flor et. al.

X-ray structures of ferritins and related proteins
score: 3.3707902, BBA - General Subjects, 2010, Crichton, Robert R.; Declercq, Jean-Paul

Structure and functional interaction of the extracellular domain of human GABA B receptor GBR2
score: 3.3707319, Nature neuroscience, 2012, Geng, Yong et. al.

A common core for binding single-stranded DNA: structural comparison of the single-stranded DNA-binding proteins (SSB) from E. coli and human mitochondria
score: 3.3704065, FEBS Letters, 1997, Webster, Gordon et. al.

Structural basis for broad substrate specificity of earthworm fibrinolytic enzyme component A
score: 3.3692852, Biochemical and Biophysical Research Communications, 2004, Wang, Chao et. al.

Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus.
score: 3.3691438, Proceedings of the National Academy of Sciences of the United States of America, 2012, Li, Qing et. al.

Structure of the Rigor Actin-Tropomyosin-Myosin Complex
score: 3.3688108, Cell, 2012, Behrmann, Elmar et. al.

DNA base damage recognition and removal: New twists and grooves
score: 3.3673245, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005, Huffman, Joy L.; Sundheim, Ottar; Tainer, John A.

Unusual Thermal Disassembly of the SPFH Domain Oligomer from Pyrococcus horikoshii
score: 3.3668453, Biophysical Journal, 2009, Kuwahara, Yohta et. al.

Calculation of ensembles of structures representing the unfolded state of an SH3 domain 1 1 Edited by P. E. Wright
score: 3.3663532, Journal of Molecular Biology, 2001, Choy, Wing-Yiu; Forman-Kay, Julie D.

Mutational analysis and NMR studies of the death domain of the tumor necrosis factor receptor-1 1 1 Edited by P. E. Wright
score: 3.3648093, Journal of Molecular Biology, 2000, Telliez, Jean-Baptiste et. al.

Twisting of the DNA-binding surface by a β-strand-bearing proline modulates DNA gyrase activity
score: 3.3644456, Nucleic Acids Research, 2010, Hsieh, Tung-Ju et. al.

An Atomic Model for Actin Binding by the CH Domains and Spectrin-repeat Modules of Utrophin and Dystrophin
score: 3.3639224, Journal of Molecular Biology, 2003, Sutherland-Smith, Andrew J et. al.

Structural Conservation of Distinctive N-terminal Acetylation-Dependent Interactions across a Family of Mammalian NEDD8 Ligation Enzymes
score: 3.3635052, Structure, 2013, Monda, Julie K. et. al.

8-THP-DHI analogs as potent Type I dual TIE-2/VEGF-R2 receptor tyrosine kinase inhibitors
score: 3.3631735, Bioorganic & Medicinal Chemistry Letters, 2010, Hudkins, Robert L. et. al.

Molecular Mechanism for Inhibition of G Protein-Coupled Receptor Kinase 2 by a Selective RNA Aptamer
score: 3.3625282, Structure, 2012, Tesmer, Valerie M. et. al.

Moving towards High-Resolution Descriptions of the Molecular Interactions and Structural Rearrangements of the Human Hepatitis B Core Protein
score: 3.3594443, Journal of Molecular Biology, 2008, Freund, Stefan M.V. et. al.

Crystal Structure of IRF-3 in Complex with CBP
score: 3.3591839, Structure, 2005, Qin, Bin Y. et. al.

Structural Insight into the Rotational Switching Mechanism of the Bacterial Flagellar Motor
score: 3.3591655, PLoS Biology, 2011, Minamino, Tohru et. al.

Synchrotron crystallography
score: 3.3588044, Trends in Biochemical Sciences, 2000, Hendrickson, Wayne A.

Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants
score: 3.3580842, FEBS Letters, 2012, Muraoka, Shin et. al.

Contrasting IgG Structures Reveal Extreme Asymmetry and Flexibility
score: 3.357816, Journal of Molecular Biology, 2002, Saphire, Erica Ollmann et. al.

Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System
score: 3.357317, Structure, 2012, Nam, Ki Hyun et. al.

Crystal structure of alkyl hydroperoxidase D like protein PA0269 from Pseudomonas aeruginosa : Homology of the AhpD-like structural family
score: 3.3570732, BMC Structural Biology, 2011, Clarke, Teresa E et. al.

Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor
score: 3.3566635, European Journal of Medicinal Chemistry, 2010, Carbone, Vincenzo et. al.

The CC1-FHA Tandem as a Central Hub for Controlling the Dimerization and Activation of Kinesin-3 KIF1A
score: 3.3562945, Structure, 2012, Huo, Lin et. al.

NMR Studies on the Substrate-binding Domains of the Thermosome: Structural Plasticity in the Protrusion Region
score: 3.3526602, Journal of Molecular Biology, 2004, Heller, Markus et. al.

Relevance of the conserved histidine and asparagine residues in the phosphate-binding loop of the nucleotide binding subunit B of A1AO ATP synthases
score: 3.3524784, Journal of Structural Biology, 2012, Tadwal, Vikeramjeet Singh et. al.

Relevance of the conserved histidine and asparagine residues in the phosphate-binding loop of the nucleotide binding subunit B of A1AO ATP synthases
score: 3.3524784, Journal of Structural Biology, 2012, Tadwal, Vikeramjeet Singh et. al.

Relevance of the conserved histidine and asparagine residues in the phosphate-binding loop of the nucleotide binding subunit B of A1AO ATP synthases
score: 3.3524784, Journal of Structural Biology, 2012, Tadwal, Vikeramjeet Singh et. al.

Ligand‐Binding Pocket of the Ecdysone Receptor
score: 3.352096, Vitamins and Hormones, 2005, Billas, Isabelle M.L.; Moras, Dino

Ligand‐Binding Pocket of the Ecdysone Receptor
score: 3.352096, Vitamins and Hormones, 2005, Billas, Isabelle M.L.; Moras, Dino

Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata.
score: 3.3517189, Proteins, 2012, Sampathkumar, Parthasarathy et. al.

Highly efficient selenomethionine labeling of recombinant proteins produced in mammalian cells.
score: 3.3504481, Protein science : a publication of the Protein Society, 2006, Barton, William A et. al.

Peptide interactions with G-protein coupled receptors.
score: 3.3488899, Biopolymers, 2001, Marshall, G R

Crystal structure of the pyrimidine 5'-nucleotidase SDT1 from Saccharomyces cerevisiae complexed with uridine 5'-monophosphate provides further insight into ligand binding.
score: 3.3475682, Proteins, 2011, Shi, Nuo et. al.

Projection structure of VP6, the rotavirus inner capsid protein, and comparison with bluetongue VP7 1 1 Edited by P. E. Wright
score: 3.343882, Journal of Molecular Biology, 1997, Hsu, George G; Bellamy, A.Richard; Yeager, Mark

Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE
score: 3.3419746, Chemico-Biological Interactions, 2005, Bourne, Yves et. al.

NMR Structure of the Bacteriophage λ N Peptide/ boxB RNA Complex: Recognition of a GNRA Fold by an Arginine-Rich Motif
score: 3.3402945, Cell, 1998, Legault, Pascale et. al.

Engineering soluble proteins for structural genomics.
score: 3.339072, Nature biotechnology, 2002, Pédelacq, Jean-Denis et. al.

Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G
score: 3.3370065, Molecular Cell, 2012, Safaee, Nozhat et. al.

Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G
score: 3.3370065, Molecular Cell, 2012, Safaee, Nozhat et. al.

PHD finger of the SUMO ligase Siz/PIAS family in rice reveals specific binding for methylated histone H3 at lysine 4 and arginine 2
score: 3.3369202, FEBS Letters, 2012, Shindo, Heisaburo et. al.

PHD finger of the SUMO ligase Siz/PIAS family in rice reveals specific binding for methylated histone H3 at lysine 4 and arginine 2
score: 3.3369202, FEBS Letters, 2012, Shindo, Heisaburo et. al.

Backbone structure of a small helical integral membrane protein: A unique structural characterization.
score: 3.3359863, Protein science : a publication of the Protein Society, 2009, Page, Richard C et. al.

The solution structure of paramagnetic metalloproteins
score: 3.3339751, Progress in Biophysics and Molecular Biology, 1996, Bertini, Ivano; Luchinat, Claudio; Rosato, Antonio

Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster
score: 3.3321758, The Febs Journal, 2012, Akif, Mohd et. al.

Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates
score: 3.3321112, Bioscience Reports, 2012, Langendorf, Christopher G. et. al.

A Class of Allosteric Caspase Inhibitors Identified by High-Throughput Screening
score: 3.3318227, Molecular Cell, 2012, Feldman, Taya et. al.

Dimer Interface Migration in a Viral Sulfhydryl Oxidase
score: 3.3312262, Journal of Molecular Biology, 2009, Hakim, Motti; Fass, Deborah

Structure-based design of 7-azaindole-pyrrolidine amides as inhibitors of 11β-hydroxysteroid dehydrogenase type I
score: 3.3304178, Bioorganic & Medicinal Chemistry Letters, 2012, Valeur, Eric et. al.

Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1.
score: 3.3294726, Proceedings of the National Academy of Sciences of the United States of America, 2012, Arita, Kyohei et. al.

Adaptation of class-13 alpha-amylases to diverse living conditions.
score: 3.3279524, Chembiochem : a European journal of chemical biology, 2004, Linden, Anni; Wilmanns, Matthias

HK97 Maturation Studied by Crystallography and H/ 2H Exchange Reveals the Structural Basis for Exothermic Particle Transitions
score: 3.327292, Journal of Molecular Biology, 2010, Gertsman, Ilya; Komives, Elizabeth A.; Johnson, John E.

Explorations of linked editosome domains leading to the discovery of motifs defining conserved pockets in editosome OB-folds
score: 3.3244549, Journal of Structural Biology, 2012, Park, Young-Jun; Hol, Wim G.J.

Explorations of linked editosome domains leading to the discovery of motifs defining conserved pockets in editosome OB-folds
score: 3.3244549, Journal of Structural Biology, 2012, Park, Young-Jun; Hol, Wim G.J.

Exploring the binding of peptidic West Nile virus NS2B–NS3 protease inhibitors by NMR
score: 3.3234705, Antiviral Research, 2013, Kang, CongBao et. al.

Structural and FunctionalAnalysis of the NLRP4 PyrinDomain
score: 3.3226478, Biochemistry, 2012, Eibl, Clarissa et. al.

Allosteric Mechanism Controls Traffic in the Chaperone/Usher Pathway
score: 3.3220753, Structure, 2012, Di Yu, Xiao et. al.

Allosteric Mechanism Controls Traffic in the Chaperone/Usher Pathway
score: 3.3220753, Structure, 2012, Di Yu, Xiao et. al.

Pharmacological characterization, structural studies, and in vivo activities of anti-Chagas disease lead compounds derived from tipifarnib.
score: 3.321371, Antimicrobial agents and chemotherapy, 2012, Buckner, Frederick S et. al.

Nucleic acid binding surface and dimer interface revealed by CRISPR-associated CasB protein structures
score: 3.3212922, FEBS Letters, 2012, Nam, Ki Hyun; Huang, Qingqiu; Ke, Ailong

Crystal structure of chloramphenicol acetyltransferase B2 encoded by the multiresistance transposon Tn2424.
score: 3.3206284, Proteins, 2004, Qiu, Wei et. al.

Factors involved in the stability of isolated beta-sheets: Turn sequence, beta-sheet twisting, and hydrophobic surface burial.
score: 3.3197415, Protein science : a publication of the Protein Society, 2004, Santiveri, Clara M et. al.

PROSESS: a protein structure evaluation suite and server
score: 3.3196526, Nucleic Acids Research, 2010, Berjanskii, Mark et. al.

Requirements on Paramagnetic Relaxation Enhancement Data for Membrane Protein Structure Determination by NMR
score: 3.3182594, Structure, 2012, Gottstein, Daniel et. al.

Requirements on Paramagnetic Relaxation Enhancement Data for Membrane Protein Structure Determination by NMR
score: 3.3182594, Structure, 2012, Gottstein, Daniel et. al.

Molecular replacement in P450 crystal structure determinations
score: 3.3166157, Methods in Enzymology, 2002, Li, Huiying; Yano, Jason K.; Poulos, Thomas L.

The GTP binding motif: variations on a theme.
score: 3.316222, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1996, Kjeldgaard, M; Nyborg, J; Clark, B F

The NMR solution structure of subunit G (G 61 – 101) of the eukaryotic V1VO ATPase from Saccharomyces cerevisiae
score: 3.3159343, BBA - Biomembranes, 2010, Rishikesan, Sankaranarayanan et. al.

Solution structure of the human Grb14-SH2 domain and comparison with the structures of the human Grb7-SH2/erbB2 peptide complex and human Grb10-SH2 domain.
score: 3.3147188, Protein science : a publication of the Protein Society, 2004, Scharf, Paul J; Witney, Jill; Daly, Roger; Lyons, Barbara A

Core Structure of the Yeast Spt4-Spt5 Complex: A Conserved Module for Regulation of Transcription Elongation
score: 3.3142875, Structure, 2008, Guo, Min et. al.

Voltage gating of Escherichia coli porin channels: role of the constriction loop.
score: 3.3140122, Proceedings of the National Academy of Sciences of the United States of America, 1997, Phale, P S et. al.

The solution structure of PapGII from uropathogenic Escherichia coli and its recognition of glycolipid receptors.
score: 3.3134977, EMBO reports, 2001, Sung, M A; Fleming, K; Chen, H A; Matthews, S

A description of the structural determination procedures of a gap junction channel at 3.5 Å resolution
score: 3.3119134, Acta Crystallographica Section D: Biological Crystallography, 2009, Suga, Michihiro et. al.

Conformational Coupling across the Plasma Membrane in Activation of the EGF Receptor
score: 3.3098916, Cell, 2013, Endres, Nicholas F. et. al.

Modelling dynamics in protein crystal structures by ensemble refinement
score: 3.3082515, eLife, 2012, Burnley, B Tom; Afonine, Pavel V; Adams, Paul D; Gros, Piet

Donor substrate recognition in the raffinose-bound E342A mutant of fructosyltransferase Bacillus subtilis levansucrase
score: 3.3078785, BMC Structural Biology, 2008, Meng, Guoyu; Fütterer, Klaus

The conserved methionine residue of the metzincins: a site-directed mutagenesis study 1 1 Edited by R. Huber
score: 3.3077461, Journal of Molecular Biology, 2001, Hege, Thomas; Baumann, Ulrich

Enzymology and structure of the GH13_31 glucan 1,6-α-glucosidase that confers isomaltooligosaccharide utilization in the probiotic Lactobacillus acidophilus NCFM.
score: 3.3076529, Journal of bacteriology, 2012, Møller, Marie S et. al.

A Method for Helical RNA Global Structure Determination in Solution Using Small-Angle X-Ray Scattering and NMR Measurements
score: 3.3075934, Journal of Molecular Biology, 2009, Wang, Jinbu et. al.

Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus
score: 3.3072077, Biochimie, 2010, Limauro, Danila et. al.

Molecular Basis for Recognition of Dilysine Trafficking Motifs by COPI
score: 3.3070373, Developmental Cell, 2012, Jackson, Lauren P. et. al.

Modeling studies with Helicobacter pylori octaprenyl pyrophosphate synthase reveal the enzymatic mechanism of trans-prenyltransferases
score: 3.3058501, International Journal of Biochemistry and Cell Biology, 2012, Zhang, Jinyong et. al.

Modeling studies with Helicobacter pylori octaprenyl pyrophosphate synthase reveal the enzymatic mechanism of trans-prenyltransferases
score: 3.3058501, International Journal of Biochemistry and Cell Biology, 2012, Zhang, Jinyong et. al.

High-yield expression and purification of isotopically labeled cytochrome P450 monooxygenases for solid-state NMR spectroscopy
score: 3.3040798, BBA - Biomembranes, 2007, Rupasinghe, Sanjeewa G. et. al.

Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex.
score: 3.3035585, Proceedings of the National Academy of Sciences of the United States of America, 2009, Nishida, Hirokazu et. al.

Solution NMR Studies of Chlorella Virus DNA Ligase-adenylate
score: 3.3017289, Journal of Molecular Biology, 2010, Piserchio, Andrea et. al.

A large data set comparison of protein structures determined by crystallography and NMR: statistical test for structural differences and the effect of crystal packing.
score: 3.2975266, Proteins, 2007, Andrec, Michael et. al.

MINOES: a new approach to select a representative ensemble of structures in NMR studies of (partially) unfolded states. Application to Delta25-PYP.
score: 3.2948899, Proteins, 2009, Krzeminski, Mickaël et. al.

Discovery of Substituted N-Phenylbenzenesulphonamides as a Novel Class of Non-Nucleoside Hepatitis C Virus Polymerase Inhibitors
score: 3.2947459, Antiviral Research, 2012, May, Marina M. et. al.

Solution structures of micelle-bound amyloid β-(1-40) and β-(1-42) peptides of Alzheimer’s disease 1 1 Edited by P. E. Wright
score: 3.293306, Journal of Molecular Biology, 1999, Shao, Haiyan; Jao, Shu-chuan; Ma, Kan; Zagorski, Michael G.

Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI.
score: 3.2920424, Proceedings of the National Academy of Sciences of the United States of America, 2012, Dhaliwal, Balvinder et. al.

Crystal structure of the dopamine N -acetyltransferase–acetyl-CoA complex provides insights into the catalytic mechanism
score: 3.290302, Biochemical Journal, 2012, Cheng, Kuo-Chang; Liao, Jhen-Ni; Lyu, Ping-Chiang

The First Crystal Structure of a Macromolecular Assembly under High Pressure: CpMV at 330 MPa
score: 3.2883933, Biophysical Journal, 2005, Girard, Eric et. al.

Class II alcohol dehydrogenase (ADH2) — adding the structure
score: 3.2874285, Chemico-Biological Interactions, 2001, Svensson, Stefan et. al.

Comparison of the structures of the cyclotheonamide A complexes of human alpha-thrombin and bovine beta-trypsin.
score: 3.2872471, Protein science : a publication of the Protein Society, 1996, Ganesh, V; Lee, A Y; Clardy, J; Tulinsky, A

Plasma Retinol-Binding Protein: Structure and Interactions with Retinol, Retinoids, and Transthyretin
score: 3.2864957, Vitamins and Hormones, 2004, Zanotti, Giuseppe; Berni, Rodolfo

Nonequivalence Observed for the 16-Meric Structure of a Small Heat Shock Protein, SpHsp16.0, fromSchizosaccharomyces pombe
score: 3.2864041, Structure, 2013, Hanazono, Yuya et. al.

Nonequivalence Observed for the 16-Meric Structure of a Small Heat Shock Protein, SpHsp16.0, fromSchizosaccharomyces pombe
score: 3.2864041, Structure, 2013, Hanazono, Yuya et. al.

Ion binding and selectivity of the rotor ring of the Na+-transporting V-ATPase.
score: 3.2859323, Proceedings of the National Academy of Sciences of the United States of America, 2008, Murata, Takeshi et. al.

Solution structure of a small protein containing a fluorinated side chain in the core.
score: 3.2832503, Protein science : a publication of the Protein Society, 2007, Cornilescu, Gabriel et. al.

The role of backbone motions in ligand binding to the c-Src SH3 domain 1 1 Edited by P. E. Wright
score: 3.2831457, Journal of Molecular Biology, 2001, Wang, Chunyu; Pawley, Norma H; Nicholson, Linda K

Structural basis for the high-affinity inhibition of mammalian membranous adenylyl cyclase by 2',3'-o-(N-methylanthraniloyl)-inosine 5'-triphosphate.
score: 3.282542, Molecular pharmacology, 2011, Hübner, Melanie et. al.

The Structure of the Plk4 Cryptic Polo Box Reveals Two Tandem Polo Boxes Required for Centriole Duplication
score: 3.2803003, Structure, 2012, Slevin, Lauren K. et. al.

The Structure of the Plk4 Cryptic Polo Box Reveals Two Tandem Polo Boxes Required for Centriole Duplication
score: 3.2803003, Structure, 2012, Slevin, Lauren K. et. al.

High-resolution macromolecular structure determination using CCD detectors and synchrotron radiation
score: 3.279956, Structure, 1995, Walter, Richard L et. al.

Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach
score: 3.2782764, BBA - Molecular Cell Research, 2004, Groll, Michael; Huber, Robert

The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b
score: 3.2774986, Structure, 2012, Baumli, Sonja et. al.

The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b
score: 3.2774986, Structure, 2012, Baumli, Sonja et. al.

Structural biology of dengue virus enzymes: Towards rational design of therapeutics
score: 3.2760554, Antiviral Research, 2012, Noble, Christian G.; Shi, Pei-Yong

Structural biology of dengue virus enzymes: Towards rational design of therapeutics
score: 3.2760554, Antiviral Research, 2012, Noble, Christian G.; Shi, Pei-Yong

Structural biology of dengue virus enzymes: Towards rational design of therapeutics
score: 3.2760554, Antiviral Research, 2012, Noble, Christian G.; Shi, Pei-Yong

Structural and immunologic characterization of bovine, horse, and rabbit serum albumins
score: 3.2755956, Molecular Immunology, 2012, Majorek, Karolina A. et. al.

Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies
score: 3.2745999, Bioorganic & Medicinal Chemistry Letters, 2005, Simone, Giuseppina De et. al.

Structural asymmetry in the Thermus thermophilus RuvC dimer suggests a basis for sequential strand cleavages during Holliday junction resolution
score: 3.2737779, Nucleic Acids Research, 2012, Chen, Luan; Shi, Ke; Yin, Zhiqi; Aihara, Hideki

Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants
score: 3.2733668, FEBS Letters, 2012, Muraoka, Shin et. al.

Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants
score: 3.2733668, FEBS Letters, 2012, Muraoka, Shin et. al.

Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants
score: 3.2733668, FEBS Letters, 2012, Muraoka, Shin et. al.

Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition.
score: 3.2718418, Proceedings of the National Academy of Sciences of the United States of America, 2010, Theodossis, Alex et. al.

Detergent Structure in Crystals of the Integral Membrane Light-harvesting Complex LH2 from Rhodopseudomonas acidophila Strain 10050
score: 3.2712876, Journal of Molecular Biology, 2003, Prince, S.M. et. al.

Structural and Biochemical Characterization of the Human Cyclophilin Family of Peptidyl-Prolyl Isomerases
score: 3.2700749, PLoS Biology, 2010, Davis, Tara L. et. al.

Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis.
score: 3.2697251, Proceedings of the National Academy of Sciences of the United States of America, 2012, Spåhr, Henrik et. al.

Structure-based optimization and biological evaluation of human 20α-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors
score: 3.2688551, European Journal of Medicinal Chemistry, 2010, El-Kabbani, Ossama et. al.

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators.
score: 3.2655292, Nature structural & molecular biology, 2011, Nishimasu, Hiroshi et. al.

Assessment of the putative binding conformation of a pyrazolopyridine class of inhibitors of MAPKAPK2 using computational studies
score: 3.264833, European Journal of Medicinal Chemistry, 2010, Miglani, Rajni; Cliffe, Ian A.; Voleti, Sreedhara R.

Crystal structures of receptors involved in small molecule transport across membranes
score: 3.2645866, European Journal of Cell Biology, 2012, Bulut, Haydar et. al.

Small terminase couples viral DNA-binding to genome-packaging ATPase activity
score: 3.2622813, Structure, 2012, Roy, Ankoor et. al.

High populations of non-native structures in the denatured state are compatible with the formation of the native folded state 1 1 Edited by P.E. Wright
score: 3.2589151, Journal of Molecular Biology, 1998, Blanco, Francisco J; Serrano, Luis; Forman-Kay, Julie D

Structural insights into the Cdt1-mediated MCM2–7 chromatin loading
score: 3.2587303, Nucleic Acids Research, 2011, Liu, Changdong et. al.

Solution structure of an antiparallel purine motif triplex containing a T·CG pyrimidine base triple
score: 3.2581901, Structure, 1996, Ji, Jie; Hogan, Michael E; Gao, Xiaolian

Structural biology of the Mre11:Nbs1 complex structure yields insights into ataxia–telangiectasia–like disease mutations and DNA damage signaling
score: 3.2555559, Nature structural & molecular biology, 2012, Schiller, Christian B. et. al.

The C-terminal priming domain is strongly associated with the main body of bacteriophage ϕ6 RNA-dependent RNA polymerase
score: 3.2548515, Virology, 2012, Sarin, L. Peter et. al.

Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor
score: 3.2547774, Structure, 2013, Gangloff, Monique et. al.

Characterization of the Solution Structure of the M Intermediate of Photoactive Yellow Protein Using High-Angle Solution X-Ray Scattering
score: 3.2543233, Biophysical Journal, 2007, Kamikubo, Hironari et. al.

Lessons from the lysozyme of phage T4.
score: 3.2535186, Protein science : a publication of the Protein Society, 2010, Baase, Walter A et. al.

A complete algorithm to resolve ambiguity for intersubunit NOE assignment in structure determination of symmetric homo-oligomers.
score: 3.2525172, Protein science : a publication of the Protein Society, 2007, Potluri, Shobha et. al.

Structural basis of yeast Tim40/Mia40 as an oxidative translocator in the mitochondrial intermembrane space.
score: 3.2524708, Proceedings of the National Academy of Sciences of the United States of America, 2009, Kawano, Shin et. al.

Rapid structural fluctuations of the free HIV protease flaps in solution: relationship to crystal structures and comparison with predictions of dynamics calculations.
score: 3.2520934, Protein science : a publication of the Protein Society, 2002, Freedberg, Darón I et. al.

NMR and molecular dynamics studies of the hydration of a zinc finger-DNA complex 1 1 Edited by M. F. Summers
score: 3.251843, Journal of Molecular Biology, 2000, Tsui, Vickie et. al.

tRNA-dependent asparagine formation in prokaryotes: Characterization, isolation and structural and functional analysis of a ribonucleoprotein particle generating Asn-tRNA Asn
score: 3.2516197, Methods, 2008, Bailly, Marc et. al.

Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a unique substrate-binding element
score: 3.2497073, Nature structural & molecular biology, 2012, Kim, In-Kwon et. al.

Biophysical methods
score: 3.2474339, Current Opinion in Structural Biology, 1996,

Progress in metallocarboxypeptidases and their small molecular weight inhibitors
score: 3.2459963, Biochimie, 2010, Fernández, Daniel et. al.

Structural and biochemical studies of the 5'→3' exoribonuclease Xrn1.
score: 3.2437883, Nature structural & molecular biology, 2011, Chang, Jeong Ho et. al.

Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference
score: 3.2399702, Bioorganic & Medicinal Chemistry, 2009, Temperini, Claudia et. al.

Three-dimensional structure of Serratia marcescens nuclease at 1.7 Å resolution and mechanism of its action
score: 3.2399193, FEBS Letters, 1997, Lunin, V.Yu et. al.

Three-dimensional structure of Serratia marcescens nuclease at 1.7 Å resolution and mechanism of its action
score: 3.2399193, FEBS Letters, 1997, Lunin, V.Yu et. al.

Structural insights into the substrate recognition properties of β-glucosidase
score: 3.23915, Biochemical and Biophysical Research Communications, 2010, Nam, Ki Hyun; Sung, Min Woo; Hwang, Kwang Yeon

Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
score: 3.2368783, EMBO reports, 2011, Lo Surdo, Paola et. al.

Experimental determination of the radiation dose limit for cryocooled protein crystals.
score: 3.2365605, Proceedings of the National Academy of Sciences of the United States of America, 2006, Owen, Robin Leslie et. al.

Solution structure of the conserved 16 S-like ribosomal RNA UGAA tetraloop 1 1 Edited by I. Tinoco
score: 3.23526, Journal of Molecular Biology, 1997, Butcher, Samuel E; Dieckmann, Thorsten; Feigon, Juli

Large Is Fast, Small Is Tight: Determinants of Speed and Affinity in Subunit Capture by a Periplasmic Chaperone
score: 3.2352469, Journal of Molecular Biology, 2012, Yu, Xiao Di et. al.

Protein thermal stability: The role of protein structure and aqueous environment
score: 3.232911, Archives of Biochemistry and Biophysics, 2007, Pechkova, Eugenia; Sivozhelezov, Victor; Nicolini, Claudio

Crystal Structure of the HLA-DM - HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection
score: 3.2326907, Cell, 2012, Pos, Wouter et. al.

High-throughput three-dimensional protein structure determination
score: 3.2319034, Current Opinion in Biotechnology, 2001, Heinemann, Udo; Illing, Gerd; Oschkinat, Hartmut

Impact of protein-protein contacts on the conformation of thrombin-bound hirudin studied by comparison with the nuclear magnetic resonance solution structure of hirudin(1–51)
score: 3.2298872, Journal of Molecular Biology, 1992, Szyperski, T. et. al.

Structural Insights into the Effect of Hydration and Ions on A-Tract DNA: A Molecular Dynamics Study
score: 3.2293069, Biophysical Journal, 2003, Madhumalar, A.; Bansal, Manju

Three-dimensional structure of the detergent-solubilized Vibrio cholerae cytolysin (VCC) heptamer by electron cryomicroscopy
score: 3.2285449, Journal of Structural Biology, 2010, He, Yongning; Olson, Rich

Structural characterization of the N-terminal oligomerization domain of the bacterial chromatin-structuring protein, H-NS 1 1 Edited by A. R. Fersht
score: 3.2281161, Journal of Molecular Biology, 2001, Renzoni, Debora et. al.

Elucidation of the mode of interaction of thermolysin with a proteinaceous metalloproteinase inhibitor, SMPI, based on a model complex structure and a structural dynamics analysis 1 1 Edited by P. E. Wright
score: 3.2276217, Journal of Molecular Biology, 1998, Tate, Shin-ichi et. al.

Nucleic acid binding surface and dimer interface revealed by CRISPR-associated CasB protein structures
score: 3.2268614, FEBS Letters, 2012, Nam, Ki Hyun; Huang, Qingqiu; Ke, Ailong

Nucleic acid binding surface and dimer interface revealed by CRISPR-associated CasB protein structures
score: 3.2268614, FEBS Letters, 2012, Nam, Ki Hyun; Huang, Qingqiu; Ke, Ailong

Nucleic acid binding surface and dimer interface revealed by CRISPR-associated CasB protein structures
score: 3.2268614, FEBS Letters, 2012, Nam, Ki Hyun; Huang, Qingqiu; Ke, Ailong

Structural analysis of H2-D b class I molecules containing two different allelic forms of the type 1 diabetes susceptibility factor beta-2 microglobulin: Implications for the mechanism underlying variations in antigen presentation
score: 3.22655, Molecular Immunology, 2006, Roden, Matthew M. et. al.

Crystal structures of an acidic phospholipase A 2 from the venom of Naja Kaouthia
score: 3.2243816, Toxicon, 2002, Gu, Lichuan et. al.

The crystal structure of the GCY1 protein from S. cerevisiae suggests a divergent aldo-keto reductase catalytic mechanism
score: 3.2243166, Chemico-Biological Interactions, 2001, Hur, Eugene; Wilson, David K.

Structure and function of KH domains.
score: 3.224232, The FEBS journal, 2008, Valverde, Roberto; Edwards, Laura; Regan, Lynne

Structure-based analysis reveals hydration changes induced by arginine hydrochloride
score: 3.2238155, Biophysical Chemistry, 2008, Nakakido, Makoto et. al.

Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
score: 3.2236846, Structure, 2012, Laughlin, John D. et. al.

Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
score: 3.2236846, Structure, 2012, Laughlin, John D. et. al.

The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage
score: 3.2234566, Journal of Molecular Biology, 2012, Wendorff, Timothy J. et. al.

The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage
score: 3.2234566, Journal of Molecular Biology, 2012, Wendorff, Timothy J. et. al.

β₂-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages.
score: 3.2209991, Nature structural & molecular biology, 2011, Liu, Cong; Sawaya, Michael R; Eisenberg, David

Three-dimensional structure of a mutant E. coli aspartate aminotransferase with increased enzymic activity.
score: 3.2201383, Protein engineering, 1994, Jäger, J; Pauptit, R A; Sauder, U; Jansonius, J N

Crystal structure of dihydrodipicolinate synthase from Hahella chejuensis at 1.5 Å resolution
score: 3.219243, International Journal of Biological Macromolecules, 2010, Kang, Beom Sik; Kim, Yeon-Gil; Ahn, Jae-Woo; Kim, Kyung-Jin

Structure of the ATP synthase catalytic complex (F 1 ) from Escherichia coli in an auto-inhibited conformation
score: 3.218552, Nature structural & molecular biology, 2011, Cingolani, Gino; Duncan, Thomas M.

Multiple Time Scale Backbone Dynamics of Homologous Thermophilic and Mesophilic Ribonuclease HI Enzymes
score: 3.2171458, Journal of Molecular Biology, 2004, Butterwick, Joel A. et. al.

Transient Structure and SH3 Interaction Sites in an Intrinsically Disordered Fragment of the Hepatitis C Virus Protein NS5A
score: 3.2168224, Journal of Molecular Biology, 2012, Feuerstein, Sophie et. al.

Transient Structure and SH3 Interaction Sites in an Intrinsically Disordered Fragment of the Hepatitis C Virus Protein NS5A
score: 3.2168224, Journal of Molecular Biology, 2012, Feuerstein, Sophie et. al.

Transient Structure and SH3 Interaction Sites in an Intrinsically Disordered Fragment of the Hepatitis C Virus Protein NS5A
score: 3.2168224, Journal of Molecular Biology, 2012, Feuerstein, Sophie et. al.

PHD finger of the SUMO ligase Siz/PIAS family in rice reveals specific binding for methylated histone H3 at lysine 4 and arginine 2
score: 3.2161222, FEBS Letters, 2012, Shindo, Heisaburo et. al.

Structure and Substrate Specificity of an SspB Ortholog: Design Implications for AAA+ Adaptors
score: 3.2147333, Structure, 2007, Chien, Peter et. al.

Structural insight into the interaction of ADP-ribose with the PARP WWE domains
score: 3.2141601, FEBS Letters, 2012, He, Fahu et. al.

Structural insight into the interaction of ADP-ribose with the PARP WWE domains
score: 3.2141601, FEBS Letters, 2012, He, Fahu et. al.

Structural insight into the interaction of ADP-ribose with the PARP WWE domains
score: 3.2141601, FEBS Letters, 2012, He, Fahu et. al.

Purification, characterization, and crystallization of alliinase from garlic
score: 3.212109, Archives of Biochemistry and Biophysics, 2002, Bartholomeus Kuettner, E. et. al.

Importance of Accurate DNA Structures in Solution: The Jun–Fos Model
score: 3.2113919, Journal of Molecular Biology, 2008, Heddi, Brahim et. al.

Activation of tRNA Maturation by Downstream Uracil Residues in B. subtilis
score: 3.2097028, Structure, 2012, Pellegrini, Olivier et. al.

Activation of tRNA Maturation by Downstream Uracil Residues in B. subtilis
score: 3.2097028, Structure, 2012, Pellegrini, Olivier et. al.

Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase.
score: 3.2092005, Proceedings of the National Academy of Sciences of the United States of America, 2010, Obeid, Samra et. al.

Comparative NMR study on the impact of point mutations on protein stability of Pseudomonas mendocina lipase.
score: 3.2086145, Protein science : a publication of the Protein Society, 2006, Sibille, Nathalie et. al.

Direct observation of hydrogen atom dynamics and interactions by ultrahigh resolution neutron protein crystallography.
score: 3.2082433, Proceedings of the National Academy of Sciences of the United States of America, 2012, Chen, Julian C-H et. al.

Structure Determination of Protein⧸RNA Complexes by NMR
score: 3.2077593, Methods in Enzymology, 2005, Wu, Haihong; Finger, L.David; Feigon, Juli

Structure Determination of Protein⧸RNA Complexes by NMR
score: 3.2077593, Methods in Enzymology, 2005, Wu, Haihong; Finger, L.David; Feigon, Juli

Crystal structure and location of gp131 in the bacteriophage phiKZ virion
score: 3.2064527, Virology, 2012, Sycheva, Lada V. et. al.

Crystal structure and location of gp131 in the bacteriophage phiKZ virion
score: 3.2064527, Virology, 2012, Sycheva, Lada V. et. al.

A new member of the ribbon-helix-helix transcription factor superfamily from the plant pathogen Xanthomonas axonopodis pv . citri
score: 3.2056701, Journal of Structural Biology, 2010, Gallo, Mariana et. al.

Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23.
score: 3.2048845, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2008, Yamazaki, Yuji et. al.

Crystal structure of the F component of the Panton-Valentine leucocidin
score: 3.2043003, International Journal of Medical Microbiology, 2000, Pédelacq, Jean-Denis et. al.

Structural Determinants for Selective Recognition of a Lys48-Linked Polyubiquitin Chain by a UBA Domain
score: 3.2032798, Molecular Cell, 2005, Varadan, Ranjani et. al.

Active site plasticity within the glycoside hydrolase NagZ underlies a dynamic mechanism of substrate distortion
score: 3.2013054, Chemistry & Biology, 2012, Bacik, John-Paul et. al.

Molecular insights into substrate specificity and thermal stability of a bacterial GH5-CBM27 endo-1,4-β-d-mannanase
score: 3.2012034, Journal of Structural Biology, 2012, Santos, Camila Ramos dos et. al.

Crystal structure and mutational analysis of human uracil-DNA glycosylase: Structural basis for specificity and catalysis
score: 3.2002717, Cell, 1995, Mol, Clifford D et. al.

Zipper-like Watson-Crick base-pairs 1 1 Edited by I. Tinoco
score: 3.1982209, Journal of Molecular Biology, 2001, Chou, Shan-Ho; Chin, Ko-Hsin

Pneumococcal phosphorylcholine esterase, Pce, contains a metal binuclear center that is essential for substrate binding and catalysis.
score: 3.1976874, Protein science : a publication of the Protein Society, 2005, Lagartera, Laura et. al.

The Metavinculin Tail Domain Directs Constitutive Interactions with Raver1 and vinculin RNA
score: 3.1969246, Journal of Molecular Biology, 2012, Lee, Jun Hyuck et. al.

Efficient identification of inhibitors targeting the closed active site conformation of the HPRT from Trypanosoma cruzi
score: 3.1963925, Chemistry & Biology, 2000, Freymann, Douglas M et. al.

Structural Basis of Rotavirus Strain Preference toward N-Acetyl- or N-Glycolylneuraminic Acid-Containing Receptors.
score: 3.1961632, Journal of virology, 2012, Yu, Xing et. al.

Synthesis and X-ray crystal structures of substituted fluorobenzene and benzoquinone inhibitors of the tissue factor VIIa complex
score: 3.1957159, Bioorganic & Medicinal Chemistry Letters, 2003, Parlow, John J. et. al.

Design and synthesis of peptides that bind α-bungarotoxin with high affinity and mimic the three-dimensional structure of the binding-site of acetylcholine receptor
score: 3.1955145, Biophysical Chemistry, 2003, Katchalski-Katzir, Ephraim et. al.

Protein crystal growth on board Shenzhou 3: a concerted effort improves crystal diffraction quality and facilitates structure determination
score: 3.1952852, Biochemical and Biophysical Research Communications, 2004, Han, Y. et. al.

Crystallographic structure and substrate-binding interactions of the molybdate-binding protein of the phytopathogen Xanthomonas axonopodis pv. citri
score: 3.1945643, BBA - Proteins and Proteomics, 2008, Balan, Andrea et. al.

Structure of components of an intercellular channel complex in sporulating Bacillus subtilis.
score: 3.1936, Proceedings of the National Academy of Sciences of the United States of America, 2012, Levdikov, Vladimir M et. al.

Structures of the Phactr1 RPEL Domain and RPEL Motif Complexes with G-Actin Reveal the Molecular Basis for Actin Binding Cooperativity
score: 3.1934593, Structure, 2012, Mouilleron, Stephane et. al.

The ternary complex of aminoacylated tRNA and EF-Tu-GTP. Recognition of a bond and a fold
score: 3.1922204, Biochimie, 1996, Nissen, P. et. al.

RecOR complex including RecR N-N dimer and RecO monomer displays a high affinity for ssDNA
score: 3.1913774, Nucleic Acids Research, 2012, Tang, Qun et. al.

News
score: 3.1910136, Journal of Molecular Graphics and Modelling, 2000,

Introduction of a disulfide bond leads to stabilization and crystallization of a ricin immunogen.
score: 3.1888653, Proteins, 2010, Compton, Jaimee R et. al.

Isothiazolidinone heterocycles as inhibitors of protein tyrosine phosphatases: Synthesis and structure–activity relationships of a peptide scaffold
score: 3.187658, Bioorganic & Medicinal Chemistry, 2006, Yue, Eddy W. et. al.

Assignment Strategies for Large Proteins by Magic-Angle Spinning NMR: The 21-kDa Disulfide-Bond-Forming Enzyme DsbA
score: 3.1849659, Journal of Molecular Biology, 2010, Sperling, Lindsay J. et. al.

A Full-Length Group 1 Bacterial Sigma Factor Adopts a Compact Structure Incompatible with DNA Binding
score: 3.184732, Chemistry & Biology, 2008, Schwartz, Edmund C. et. al.

Heterologous expression, purification, crystallization, X-ray analysis and phasing of the acetyl xylan esterase from Bacillus pumilus
score: 3.1846021, BBA - Proteins and Proteomics, 2005, Krastanova, Ivet et. al.

Protein Structures at Atomic Resolution
score: 3.1843003, Methods in Enzymology, 2003, Dauter, Zbigniew

Structure-based design of cyclin-dependent kinase inhibitors
score: 3.1837877, Pharmacology and Therapeutics, 2002, Davies, Thomas G. et. al.

Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease.
score: 3.1835955, Proceedings of the National Academy of Sciences of the United States of America, 1995, Reich, S H et. al.

Elucidation of the contribution of active site and exosite interactions to affinity and specificity of peptidylic serine protease inhibitors using non-natural arginine analogs.
score: 3.1835685, Molecular pharmacology, 2011, Hosseini, Masood et. al.

Crystallization and preliminary X-ray crystallographic analysis of the N-terminal photosensory module of phytochrome Agp1, a biliverdin-binding photoreceptor from Agrobacterium tumefaciens
score: 3.1812214, Journal of Structural Biology, 2006, Scheerer, Patrick et. al.

Folding and binding
score: 3.1796036, Current Opinion in Structural Biology, 1997,

Dynamic Dysfunction in Dihydrofolate Reductase Results from Antifolate Drug Binding: Modulation of Dynamics within a Structural State
score: 3.1795599, Structure, 2009, Mauldin, Randall V.; Carroll, Mary J.; Lee, Andrew L.

Sulfotransferase structural biology and inhibitor discovery
score: 3.1790831, Drug Discovery Today, 2004, Rath, Virginia L.; Verdugo, Dawn; Hemmerich, Stefan

Design, synthesis, structure and binding properties of PDZ binding, cyclic β-finger peptides
score: 3.1789731, Biochemical and Biophysical Research Communications, 2010, Seedorff, Sabine et. al.

Rational design of inhibitors that bind to inactive kinase conformations.
score: 3.1773082, Nature chemical biology, 2006, Liu, Yi; Gray, Nathanael S

T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo.
score: 3.1770259, Journal of immunology (Baltimore, Md. : 1950), 2005, Webb, Andrew I et. al.

Validation of protein models derived from experiment
score: 3.1769983, Current Opinion in Structural Biology, 1998, Laskowski, Roman A; MacArthur, Malcolm W; Thornton, Janet M

Determining the structures of large proteins and protein complexes by NMR
score: 3.176852, Trends in Biotechnology, 1998, Clore, G. Marius; Gronenborn, Angela M.

Small Terminase Couples Viral DNA Binding to Genome-Packaging ATPase Activity
score: 3.175819, Structure, 2012, Roy, Ankoor et. al.

Tail-Mediated Collapse of HMGB1 Is Dynamic and Occurs via Differential Binding of the Acidic Tail to the A and B Domains
score: 3.1748629, Journal of Molecular Biology, 2010, Stott, Katherine et. al.

Improved expression, purification, and crystallization of p38α MAP kinase
score: 3.1739282, Protein Expression and Purification, 2004, Bukhtiyarova, Marina et. al.

A crystal structure of a dimer of the antibiotic ramoplanin illustrates membrane positioning and a potential Lipid II docking interface.
score: 3.1711403, Proceedings of the National Academy of Sciences of the United States of America, 2009, Hamburger, James B et. al.

The SAXS Solution Structure of RF1 Differs from Its Crystal Structure and Is Similar to Its Ribosome Bound Cryo-EM Structure
score: 3.1703502, Molecular Cell, 2005, Vestergaard, Bente et. al.

The structural basis for seryl-adenylate and Ap 4A synthesis by seryl-tRNA synthetase
score: 3.1674177, Structure, 1995, Belrhali, Hassan et. al.

Solution Structure of the Capsid Protein from the Human T-cell Leukemia Virus Type-I
score: 3.1673475, Journal of Molecular Biology, 1999, Khorasanizadeh, Sepideh et. al.

Solution Structure of the Capsid Protein from the Human T-cell Leukemia Virus Type-I
score: 3.1673475, Journal of Molecular Biology, 1999, Khorasanizadeh, Sepideh et. al.

FAM3B PANDER and FAM3C ILEI Represent a Distinct Class of Signaling Molecules with a Non-Cytokine-like Fold
score: 3.1664056, Structure, 2013, Johansson, Patrik et. al.

Comprehensive NOE characterization of a partially folded large fragment of staphylococcal nuclease Δ131Δ, using NMR methods with improved resolution 1 1 Edited by P. E. Wright
score: 3.1653746, Journal of Molecular Biology, 1997, Zhang, Ouwen et. al.

Solution NMR studies of the integral membrane proteins OmpX and OmpA from Escherichia coli
score: 3.1650851, FEBS Letters, 2001, Fernández, César et. al.

Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cδ∗
score: 3.1648089, Biophysical Journal, 2012, Shanmugasundararaj, Sivananthaperumal et. al.

Water molecules in DNA recognition II: a molecular dynamics view of the structure and hydration of the trp operator 1 1 Edited by B. Honig
score: 3.1647047, Journal of Molecular Biology, 1998, Bonvin, Alexandre M.J.J. et. al.

Isomorphous replacement of cystine with selenocystine in endothelin: oxidative refolding, biological and conformational properties of [Sec 3,Sec 11,Nle 7]-endothelin-1 1 1 Edited by R. Huber
score: 3.1638073, Journal of Molecular Biology, 1998, Pegoraro, Stefano et. al.

Structural basis for sirtuin function: What we know and what we don't
score: 3.1636765, BBA - Proteins and Proteomics, 2010, Sanders, Brandi D.; Jackson, Brittany; Marmorstein, Ronen

Characterization of peptide deformylase homologues from Staphylococcus epidermidis.
score: 3.1634957, Microbiology (Reading, England), 2010, Lin, Penghui et. al.

Stereospecific assignments of protein NMR resonances based on the tertiary structure and 2D/3D NOE data.
score: 3.1622388, Journal of computational chemistry, 2006, Pristovsek, Primoz; Franzoni, Lorella

Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer
score: 3.1610491, Bioorganic & Medicinal Chemistry, 2010, Sun, Bin et. al.

Structure and dynamics of the ATP-bound open conformation of Hsp70 chaperones
score: 3.1603025, Molecular Cell, 2012, Kityk, Roman et. al.

Interaction analysis between tmRNA and SmpB from Thermus thermophilus.
score: 3.1540563, Journal of biochemistry, 2005, Nameki, Nobukazu et. al.

Chapter 20 Expression, Reconstitution, and Structure of an Archaeal RNA Degrading Exosome
score: 3.1533789, Methods in Enzymology, 2008, Lorentzen, Esben; Conti, Elena

Chemistry and biology of the aeruginosin family of serine protease inhibitors.
score: 3.1487081, Angewandte Chemie (International ed. in English), 2008, Ersmark, Karolina; Del Valle, Juan R; Hanessian, Stephen

Hydroxynitrile lyases with α/β-hydrolase fold: two enzymes with almost identical 3D structures but opposite enantioselectivities and different reaction mechanisms.
score: 3.1462012, Chembiochem : a European journal of chemical biology, 2012, Andexer, Jennifer N et. al.

Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy.
score: 3.1459505, Nature structural & molecular biology, 2012, Ummat, Ajay et. al.

Crystal structure of the secretory isozyme of mammalian carbonic anhydrases CA VI: Implications for biological assembly and inhibitor development
score: 3.14474, Biochemical and Biophysical Research Communications, 2012, Pilka, Ewa S. et. al.

Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity
score: 3.1434036, Journal of Inorganic Biochemistry, 2012, Qin, Jie et. al.

Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity
score: 3.1434036, Journal of Inorganic Biochemistry, 2012, Qin, Jie et. al.

Picosecond time-resolved X-ray crystallography: probing protein function in real time
score: 3.1413649, Journal of Structural Biology, 2004, Schotte, Friedrich et. al.

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme
score: 3.1412172, Open biology, 2012, Fullam, Elizabeth et. al.

Structural basis for the neutralization and genotype specificity of hepatitis E virus.
score: 3.1411287, Proceedings of the National Academy of Sciences of the United States of America, 2011, Tang, Xuhua et. al.

Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration
score: 3.1405551, Journal of Structural Biology, 2012, Tu, Xiongying; Palczewski, Krzysztof

Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration
score: 3.1405551, Journal of Structural Biology, 2012, Tu, Xiongying; Palczewski, Krzysztof

The X-ray Crystal Structure of Full-Length Human Plasminogen
score: 3.1401243, Cell Reports, 2012, Law, Ruby H.P. et. al.

The X-ray Crystal Structure of Full-Length Human Plasminogen
score: 3.1401243, Cell Reports, 2012, Law, Ruby H.P. et. al.

Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase
score: 3.1397991, Nucleic Acids Research, 2012, Ito, Kosuke et. al.

Protein engineering the surface of enzymes
score: 3.1396754, Journal of Biotechnology, 1998, Petersen, Steffen B. et. al.

An FcγRIIa-binding peptide that mimics the interaction between FcγRIIa and IgG
score: 3.1390353, Molecular Immunology, 2008, Cendron, Angela C. et. al.

Structural Basis for the Interaction of Unstructured Neuron Specific Substrates Neuromodulin and Neurogranin with Calmodulin
score: 3.1380437, Scientific Reports, 2013, Kumar, Veerendra et. al.

Molecular mechanism for inhibition of G protein-coupled receptor kinase 2 by a selective RNA aptamer
score: 3.1366783, Structure, 2012, Tesmer, Valerie M. et. al.

A CapG gain-of-function mutant reveals critical structural and functional determinants for actin filament severing.
score: 3.1361811, The EMBO journal, 2006, Zhang, Y et. al.

Structural basis for the sheddase function of human meprin β metalloproteinase at the plasma membrane.
score: 3.1350448, Proceedings of the National Academy of Sciences of the United States of America, 2012, Arolas, Joan L et. al.

Structure-fluorescence correlations in a single tryptophan mutant of carp parvalbumin: solution structure, backbone and side-chain dynamics 1 1 Edited by P. E. Wright
score: 3.1342886, Journal of Molecular Biology, 2000, Moncrieffe, Martin C. et. al.

Conformation of a Trimannoside Bound to Mannose-Binding Protein by Nuclear Magnetic Resonance and Molecular Dynamics Simulations
score: 3.1329471, Biophysical Journal, 2002, Sayers, Eric W.; Prestegard, James H.

Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs
score: 3.1305045, Biochemical and Biophysical Research Communications, 2012, Clark, Shawn A.; Davulcu, Omar; Chapman, Michael S.

Crystal structures of arginine kinase in complex with ADP, nitrate, and various phosphagen analogs
score: 3.1305045, Biochemical and Biophysical Research Communications, 2012, Clark, Shawn A.; Davulcu, Omar; Chapman, Michael S.

Solution Conformations of Prototype Foamy Virus Integrase and Its Stable Synaptic Complex with U5 Viral DNA
score: 3.1301313, Structure, 2012, Gupta, Kushol et. al.

Solution Conformations of Prototype Foamy Virus Integrase and Its Stable Synaptic Complex with U5 Viral DNA
score: 3.1301313, Structure, 2012, Gupta, Kushol et. al.

Ribosomal Protein L9: A Structure Determination by the Combined Use of X-ray Crystallography and NMR Spectroscopy
score: 3.1293329, Journal of Molecular Biology, 1996, Hoffman, David W. et. al.

PHD Finger of the SUMO Ligase Siz/PIAS Family in Rice Reveals Specific Binding for Methylated Histone H3 at Lysine 4 and Arginine 2
score: 3.1280882, FEBS Letters, 2012, Shindo, Heisaburo et. al.

Role of a solvent-exposed tryptophan in the recognition and binding of antibiotic substrates for a metallo-beta-lactamase.
score: 3.1265873, Protein science : a publication of the Protein Society, 2003, Huntley, James J A et. al.

Crystal Structure Determination of Escherichia coliClpP Starting from an EM-Derived Mask
score: 3.1250611, Journal of Structural Biology, 1998, Wang, Jimin; Hartling, James A.; Flanagan, John M.

Identification of a hydrogen bond in the Phe M197→Tyr mutant reaction center of the photosynthetic purple bacterium Rhodobacter sphaeroides by X-ray crystallography and FTIR spectroscopy 1 1 Parts of the crystallographic results presented in this article have already been published in G. Garab (Ed.) (1998) Photosynthesis: Mechanisms and Effects, Vol. II, pp. 699–702, Kluwer Academic, Dordrecht.
score: 3.1250458, FEBS Letters, 1999, Kuglstatter, Andreas et. al.

Comparative biophysical characterization of chicken β2-microglobulin
score: 3.1236971, Biophysical Chemistry, 2012, Hee, Chee-Seng et. al.

Guanidinobenzoic acid inhibitors of influenza virus neuraminidase 1 1 Edited by R. Huber
score: 3.1218375, Journal of Molecular Biology, 1997, Sudbeck, E.A et. al.

Towards structural elucidation of eukaryotic photosystem II: Purification, crystallization and preliminary X-ray diffraction analysis of photosystem II from a red alga
score: 3.1215142, BBA - Bioenergetics, 2009, Adachi, Hideyuki et. al.

Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D β-lactamase OXA-10 by rational protein design.
score: 3.1213285, Proceedings of the National Academy of Sciences of the United States of America, 2011, De Luca, Filomena et. al.

NMR Constraints Analyser: a web-server for the graphical analysis of NMR experimental constraints
score: 3.1212966, Nucleic Acids Research, 2010, Heller, Davide Martin; Giorgetti, Alejandro

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
score: 3.1212085, Nature, 2012, Plechanovová, Anna et. al.

Crystallization and preliminary structural analysis of catalase A from Saccharomyces cerevisiae.
score: 3.1211095, Protein science : a publication of the Protein Society, 1997, Berthet, S et. al.

Structural and immunologic characterization of bovine, horse, and rabbit serum albumins
score: 3.1207156, Molecular Immunology, 2012, Majorek, Karolina A. et. al.

Structural and immunologic characterization of bovine, horse, and rabbit serum albumins
score: 3.1207156, Molecular Immunology, 2012, Majorek, Karolina A. et. al.

Structural and immunologic characterization of bovine, horse, and rabbit serum albumins
score: 3.1207156, Molecular Immunology, 2012, Majorek, Karolina A. et. al.

Protein production in Escherichia coli for structural studies by X-ray crystallography
score: 3.120601, Journal of Structural Biology, 2003, Goulding, Celia W; Jeanne Perry, L

X-Ray analysis of d(CGCGAATTXGCG) 2 containing a 2′-deoxy- N 4-methoxycytosine residue at X: a characteristic pattern of sugar puckers in the crystalline state of the Dickerson–Drew type DNA dodecamers
score: 3.1186768, Biophysical Chemistry, 2002, Tofazzal Hossain, M et. al.

Structure, dynamics and mapping of membrane-binding residues of micelle-bound antimicrobial peptides by natural abundance 13C NMR spectroscopy
score: 3.1174857, BBA - Biomembranes, 2010, Wang, Guangshun

NMR studies of the fifth transmembrane segment of sarcoplasmic reticulum Ca 2+-ATPase reveals a hinge close to the Ca 2+-ligating residues
score: 3.1173733, FEBS Letters, 2003, Nielsen, Gerd et. al.

Two crucial early steps in RNA synthesis by the hepatitis C virus polymerase involve a dual role of residue 405.
score: 3.116145, Journal of virology, 2012, Scrima, Nathalie et. al.

Conserved water molecules contribute to the extensive network of interactions at the active site of protein kinase A.
score: 3.1154532, Proceedings of the National Academy of Sciences of the United States of America, 1998, Shaltiel, S; Cox, S; Taylor, S S

An inactive pancreatic—related protein is activated into a triglyceride-lipase by mutagenesis based on the 3-D structure
score: 3.1141234, Chemistry and Physics of Lipids, 1998, Bezzine, Sofiane et. al.

Purification, crystallisation and preliminary crystallographic studies of succinate:ubiquinone oxidoreductase from Escherichia coli
score: 3.1139498, BBA - Bioenergetics, 2002, Törnroth, Susanna et. al.

Conformational state of the MscS mechanosensitive channel in solution revealed by pulsed electron-electron double resonance (PELDOR) spectroscopy.
score: 3.1123616, Proceedings of the National Academy of Sciences of the United States of America, 2012, Pliotas, Christos et. al.

A cyclic disulfide peptide reproduces in solution the main structural features of a native antigenic site of foot-and-mouth disease virus
score: 3.1119237, International Journal of Biological Macromolecules, 1997, Haack, Thomas et. al.

Rigid-body Ligand Recognition Drives Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Receptor Triggering
score: 3.1118683, The Journal of Biological Chemistry, 2010, Yu, Chao et. al.

Structure and dynamics of the human muscle LIM protein
score: 3.1115653, FEBS Letters, 2009, Schallus, Thomas et. al.

Peptide bis-intercalator binds DNA via threading mode with sequence specific contacts in the major groove
score: 3.1099708, Chemistry & Biology, 2001, Guelev, Vladimir et. al.

Accurate protein structure modeling using sparse NMR data and homologous structure information.
score: 3.1099182, Proceedings of the National Academy of Sciences of the United States of America, 2012, Thompson, James M et. al.

CryoEM Structure at 9 Å Resolution of an Adenovirus Vector Targeted to Hematopoietic Cells
score: 3.1083012, Journal of Molecular Biology, 2005, Saban, Susan D. et. al.

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase
score: 3.106568, Chemistry & Biology, 1997, Wilson, Keith P. et. al.

Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications
score: 3.1060349, Bioorganic & Medicinal Chemistry, 2004, Van Zandt, Michael C. et. al.

Structural insights into the regulation of cohesion establishment by Wpl1
score: 3.1056639, The EMBO Journal, 2013, Chatterjee, Avradip et. al.

Crystal structures of modified apo-His117Gly and apo-His46Gly mutants of Pseudomonas aeruginosa azurin a a Edited by I. A. Wilson
score: 3.1055211, Journal of Molecular Biology, 1997, Hammann, Christian et. al.

Potent Inhibition of HIV-1 Fusion by Cyanovirin-N Requires Only a Single High Affinity Carbohydrate Binding Site: Characterization of Low Affinity Carbohydrate Binding Site Knockout Mutants
score: 3.1045582, Journal of Molecular Biology, 2002, Chang, Leng Chee; Bewley, Carole A.

Solution structure of the Big domain from Streptococcus pneumoniae reveals a novel Ca 2+ -binding module
score: 3.103256, Scientific Reports, 2013, Wang, Tao et. al.

Incorporation of β-selenolo[3,2- b]pyrrolyl-alanine into proteins for phase determination in protein X-ray crystallography 1 1 Edited by K. Nagai
score: 3.1018511, Journal of Molecular Biology, 2001, Bae, Jae Hyun et. al.

Analysis of Structural Dynamics in the Ribosome by TLS Crystallographic Refinement
score: 3.1016292, Journal of Molecular Biology, 2007, Korostelev, Andrei; Noller, Harry F.

Insights for the development of specific kinase inhibitors by targeted structural genomics
score: 3.1015797, Drug Discovery Today, 2007, Fedorov, Oleg et. al.

The 3D structure of the anticancer prodrug CPT-11 with Torpedo californica acetylcholinesterase rationalizes its inhibitory action on AChE and its hydrolysis by butyrylcholinesterase and carboxylesterase
score: 3.1011658, Chemico-Biological Interactions, 2005, Harel, Michal et. al.

A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction.
score: 3.0986843, Journal of virology, 2009, Diaz-Griffero, Felipe et. al.

Structural and functional similarities in the ADP-forming amide bond ligase superfamily: implications for a substrate-induced conformational change in folylpolyglutamate synthetase 1 1 Edited by I. A. Wilson
score: 3.0964595, Journal of Molecular Biology, 2000, Sheng, Yi et. al.

A single amino acid substitution in Staphylococcus aureus dihydrofolate reductase determines trimethoprim resistance 1 1 Edited by T.Richmond
score: 3.0958134, Journal of Molecular Biology, 1997, Dale, Glenn E. et. al.

Structural insights into electron transfer in caa 3 -type cytochrome oxidase
score: 3.095813, Nature, 2012, Lyons, Joseph A. et. al.

New methods of structure refinement for macromolecular structure determination by NMR.
score: 3.0955318, Proceedings of the National Academy of Sciences of the United States of America, 1998, Clore, G M; Gronenborn, A M

Solution structures of the double-stranded RNA-binding domains from RNA helicase A.
score: 3.0949674, Proteins, 2012, Nagata, Takashi et. al.

The tandem Src homology 2 domain of the Syk kinase: a molecular device that adapts to interphosphotyrosine distances.
score: 3.0940373, Proceedings of the National Academy of Sciences of the United States of America, 2003, Kumaran, Sangaralingam; Grucza, Richard A; Waksman, Gabriel

Ego3 Functions as a Homodimer to Mediate the Interaction between Gtr1-Gtr2 and Ego1 in the EGO Complex to Activate TORC1
score: 3.0939889, Structure, 2012, Zhang, Tianlong et. al.

Ego3 Functions as a Homodimer to Mediate the Interaction between Gtr1-Gtr2 and Ego1 in the EGO Complex to Activate TORC1
score: 3.0939889, Structure, 2012, Zhang, Tianlong et. al.

Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis
score: 3.0939608, Cell, 2012, Ragusa, Michael J.; Stanley, Robin E.; Hurley, James H.

Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis
score: 3.0939608, Cell, 2012, Ragusa, Michael J.; Stanley, Robin E.; Hurley, James H.

Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine–guanine phosphoribosyltransferase
score: 3.0907304, BBA - Proteins and Proteomics, 2002, Monzani, Paulo S. et. al.

Structure and function of AvtR, a novel transcriptional regulator from a hyperthermophilic archaeal lipothrixvirus.
score: 3.0847957, Journal of virology, 2012, Peixeiro, N et. al.

Three-dimensional structure of a barnase-3'GMP complex at 2.2Å resolution
score: 3.0847081, FEBS Letters, 1993, Guillet, Valéric; Lapthorn, Adrian; Mauguen, Yves

The Structural Impact of a Polyglutamine Tract Is Location-Dependent
score: 3.0816888, Biophysical Journal, 2008, Robertson, Amy L. et. al.

The Structural Impact of a Polyglutamine Tract Is Location-Dependent
score: 3.0816888, Biophysical Journal, 2008, Robertson, Amy L. et. al.

Structural Insights into the Association between BCAR3 and Cas Family Members, an Atypical Complex Implicated in Anti-Oestrogen Resistance
score: 3.0776623, Journal of Molecular Biology, 2009, Garron, Marie-Line et. al.

Non-peptidic small molecule inhibitors of XIAP
score: 3.0774265, Bioorganic & Medicinal Chemistry Letters, 2005, Park, Cheol-Min et. al.

Crystal Structure of a 9-Subunit Archaeal Exosome in Pre-Catalytic States of the Phosphorolytic Reaction
score: 3.0769577, Archaea, 2012, Lorentzen, Esben; Conti, Elena

Crystal structure of human PNP complexed with hypoxanthine and sulfate ion
score: 3.0769389, Biochemical and Biophysical Research Communications, 2005, Canduri, Fernanda et. al.

Structural characterization of the Hepatitis C Virus NS3 protease from genotype 3a: The basis of the genotype 1b vs. 3a inhibitor potency shift
score: 3.0768187, Virology, 2010, Gallo, Mariana et. al.

Turn up the HEAT
score: 3.0767162, Structure, 1999, Kobe, Bostjan et. al.

LSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 Demethylation
score: 3.076527, Molecular Cell, 2013, Fang, Rui et. al.

Structural investigation of mutant Mycobacterium smegmatis arylamine N-acetyltransferase: a model for a naturally occurring functional polymorphism in Mycobacterium tuberculosis arylamine N-acetyltransferase
score: 3.0762366, Protein Expression and Purification, 2003, Kawamura, Akane et. al.

The detailed structure of tandem G·A mismatched base-pair motifs in RNA duplexes is context dependent 1 1 Edited by I. Tinoco
score: 3.0759327, Journal of Molecular Biology, 1997, Heus, Hans A. et. al.

Unique MAP Kinase binding sites
score: 3.075667, BBA - Proteins and Proteomics, 2008, Akella, Radha; Moon, Thomas M.; Goldsmith, Elizabeth J.

Formation of the single-layer β-sheet of Borrelia burgdorferi OspA in the absence of the C-terminal capping globular domain 1 1 Edited by P. E. Wright
score: 3.0716336, Journal of Molecular Biology, 2001, Huang, Xiaolin et. al.

Ribulose bisphosphate carboxylase/oxygenase from the hyperthermophilic archaeon Pyrococcus kodakaraensis KOD1 is composed solely of large subunits and forms a pentagonal structure 1 1 Edited by R. Huber
score: 3.0714148, Journal of Molecular Biology, 1999, Maeda, Norihiro et. al.

Plant Photosystem I Design in the Light of Evolution
score: 3.0689908, Structure, 2009, Amunts, Alexey; Nelson, Nathan

β 2 -microglobulin forms 3D domain-swapped amyloid fibrils with disulfide linkages
score: 3.0686537, Nature structural & molecular biology, 2010, Liu, Cong; Sawaya, Michael R.; Eisenberg, David

Binding Hot Spot in the Weak Protein Complex of Physiological Redox Partners Yeast Cytochrome c and Cytochrome c Peroxidase
score: 3.0685588, Journal of Molecular Biology, 2009, Volkov, Alexander N. et. al.

Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus
score: 3.0679482, FEBS Letters, 2013, Fisher, Oriana S. et. al.

Purification and preliminary X-ray studies on hen serotransferrin in apo- and holo-forms
score: 3.0675793, Biochemical and Biophysical Research Communications, 2002, Choudhury, Debi et. al.

Structural basis for controlling the dimerization and stability of the WW domains of an atypical subfamily.
score: 3.0672254, Protein science : a publication of the Protein Society, 2008, Ohnishi, Satoshi et. al.

Crystal structure of activated tobacco rubisco complexed with the reaction-intermediate analogue 2-carboxy-arabinitol 1,5-bisphosphate.
score: 3.0669304, Protein science : a publication of the Protein Society, 1993, Schreuder, H A et. al.

Chaperone-Assisted Crystallography with DARPins
score: 3.0633023, Structure, 2008, Sennhauser, Gaby; Grütter, Markus G.

Low pH crystal structure of glycosylated lignin peroxidase from Phanerochaete chrysosporium at 2.5 Å resolution
score: 3.0619318, FEBS Letters, 1993, Piontek, Klaus; Glumoff, Tuomo; Winterhalter, Kaspar

Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2.
score: 3.0597664, Proceedings of the National Academy of Sciences of the United States of America, 2005, Holm, Mai Marie et. al.

Solution Structure and Sugar-Binding Mechanism of Mouse Latrophilin-1 RBL: a 7TM Receptor-Attached Lectin-Like Domain
score: 3.058733, Structure, 2008, Vakonakis, Ioannis et. al.

Solution Structure and Characterisation of the Human Pyruvate Dehydrogenase Complex Core Assembly
score: 3.0583463, Journal of Molecular Biology, 2010, Vijayakrishnan, S. et. al.

The long-chain fatty acid sensor, PsrA, modulates the expression of rpoS and the type III secretion exsCEBA operon in Pseudomonas aeruginosa.
score: 3.0570006, Molecular microbiology, 2009, Kang, Yun et. al.

Analysis of structure-function relationships in the colibactin-maturating enzyme ClbP
score: 3.0541098, Journal of Molecular Biology, 2012, Cougnoux, Antony et. al.

Contribution of explicit solvent effects to the binding affinity of small-molecule inhibitors in blood coagulation factor serine proteases.
score: 3.0535403, ChemMedChem, 2011, Abel, Robert et. al.

The evolution of an allosteric site in phosphorylase
score: 3.0531245, Structure, 1996, Rath, Virginia L et. al.

Formation of nNOS/PSD-95 PDZ dimer requires a preformed β-finger structure from the nNOS PDZ domain 1 1 Edited by M. F. Summers
score: 3.0522089, Journal of Molecular Biology, 2000, Tochio, Hidehito et. al.

Structure and plasticity of the peptidyl-prolyl isomerase Par27 of Bordetella pertussis revealed by X-ray diffraction and small-angle X-ray scattering
score: 3.0515635, Journal of Structural Biology, 2010, Clantin, Bernard et. al.

Greater efficiency of photosynthetic carbon fixation due to single amino-acid substitution
score: 3.0513148, Nature Communications, 2013, Paulus, Judith Katharina; Schlieper, Daniel; Groth, Georg

ACET is a highly potent and specific kainate receptor antagonist: Characterisation and effects on hippocampal mossy fibre function
score: 3.0498273, Neuropharmacology, 2009, Dargan, Sheila L. et. al.

Hydrogen bonds with π-acceptors in proteins: frequencies and role in stabilizing local 3D structures 1 1 Edited by R. Huber
score: 3.0486325, Journal of Molecular Biology, 2001, Steiner, Thomas; Koellner, Gertraud

A Simple Model of Backbone Flexibility Improves Modeling of Side-chain Conformational Variability
score: 3.0479429, Journal of Molecular Biology, 2008, Friedland, Gregory D. et. al.

Structure of a protein-DNA complex essential for DNA protection in spores of Bacillus species.
score: 3.0465589, Proceedings of the National Academy of Sciences of the United States of America, 2008, Lee, Ki Seog et. al.

Yeast Cytosine Deaminase Mutants with Increased Thermostability Impart Sensitivity to 5-Fluorocytosine
score: 3.0456259, Journal of Molecular Biology, 2008, Stolworthy, Tiffany S. et. al.

Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T.
score: 3.0451056, Proceedings of the National Academy of Sciences of the United States of America, 2008, Murakami, Kenji et. al.

The NMR structure of the murine DLC2 SAM domain reveals a variant fold that is similar to a four-helix bundle
score: 3.042331, BMC Structural Biology, 2007, Kwan, Jamie J; Donaldson, Logan W

Structural determinants of the specificity of a membrane binding domain of the scaffold protein Ste5 of budding yeast: Implications in signaling by the scaffold protein in MAPK pathway
score: 3.0414293, BBA - Biomembranes, 2012, Bhunia, Anirban; Mohanram, Harini; Bhattacharjya, Surajit

Structural determinants of the specificity of a membrane binding domain of the scaffold protein Ste5 of budding yeast: Implications in signaling by the scaffold protein in MAPK pathway
score: 3.0414293, BBA - Biomembranes, 2012, Bhunia, Anirban; Mohanram, Harini; Bhattacharjya, Surajit

How the multifunctional yeast Rap1p discriminates between DNA target sites: a crystallographic analysis 1 1 Edited by T. R. Richmond
score: 3.0399986, Journal of Molecular Biology, 2000, Taylor, Helena O.B et. al.

Solution structure of urotensin-II receptor extracellular loop III and characterization of its interaction with urotensin-II
score: 3.0399419, Peptides, 2008, Boivin, Stéphane et. al.

X-ray structures of three interface mutants of gammaB-crystallin from bovine eye lens.
score: 3.0396607, Protein science : a publication of the Protein Society, 1998, Palme, S; Jaenicke, R; Slingsby, C

Peptaibol Zervamicin IIB Structure and Dynamics Refinement from Transhydrogen Bond J Couplings
score: 3.0390243, Biophysical Journal, 2004, Shenkarev, Z.O. et. al.

Protein crystal content analysis by mass spectrometry and preliminary X-ray diffraction of a lectin from Canavalia grandiflora seeds with modulatory role in inflammation.
score: 3.0383205, Rapid communications in mass spectrometry : RCM, 2012, Simões, Rafael Conceição et. al.

Mycobacterium tuberculosis Universal Stress Protein Rv2623 Regulates Bacillary Growth by ATP-Binding: Requirement for Establishing Chronic Persistent Infection
score: 3.0338889, PLoS Pathogens, 2009, Drumm, Joshua E. et. al.

Structural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein libraries.
score: 3.0329615, Proceedings of the National Academy of Sciences of the United States of America, 2012, Kummer, Lutz et. al.

NMR Structure of Lipoprotein YxeF from Bacillus subtilis Reveals a Calycin Fold and Distant Homology with the Lipocalin Blc from Escherichia coli
score: 3.0320591, PLoS ONE, 2012, Wu, Yibing et. al.

Crystal Structures of the Clock Protein EA4 from the Silkworm Bombyx mori
score: 3.0295689, Journal of Molecular Biology, 2008, Hiraki, Toshiki et. al.

Cross-beta Order and Diversity in Nanocrystals of an Amyloid-forming Peptide
score: 3.027751, Journal of Molecular Biology, 2003, Diaz-Avalos, Ruben et. al.

Protein titration in the crystal state 1 1 Edited by A. R. Fersht
score: 3.0257324, Journal of Molecular Biology, 1999, Berisio, R et. al.

Crystal structure of mastoparan from Polistes jadwagae at 1.2 Å resolution
score: 3.0254832, Journal of Structural Biology, 2007, Liu, ShengQuan et. al.

Unique Regulation of the Active site of the Serine Esterase S-Formylglutathione Hydrolase
score: 3.025183, Journal of Molecular Biology, 2006, Cummins, Ian et. al.

Receptor and substrate interactions of clostridial neurotoxins
score: 3.0250121, Toxicon, 2009, Brunger, Axel T.; Rummel, Andreas

Elucidating the mechanism of familial amyloidosis- Finnish type: NMR studies of human gelsolin domain 2.
score: 3.0215176, Proceedings of the National Academy of Sciences of the United States of America, 2000, Kazmirski, S L; Howard, M J; Isaacson, R L; Fersht, A R

Crystallization and preliminary X-ray diffraction analysis of the extracellular domain of the cell surface antigen CD38 complexed with ganglioside.
score: 3.0183513, Journal of biochemistry, 2000, Kukimoto, M et. al.

The Dynamic Structure of Thrombin in Solution
score: 3.0174204, Biophysical Journal, 2012, Fuglestad, Brian et. al.

A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin
score: 3.0155445, Biochemical Journal, 2011, Tseng, Tien-Sheng et. al.

Micelle-bound conformation of a hairpin-forming peptide: combined NMR and molecular dynamics study.
score: 3.0140745, Biopolymers, 2002, Dixon, Ann M et. al.

The structural basis of differential DNA sequence recognition by restriction–modification controller proteins
score: 3.0140397, Nucleic Acids Research, 2012, Ball, N. J. et. al.

Structure of STING bound to c-di-GMP Reveals the Mechanism of Cyclic Dinucleotide Recognition by the Immune System
score: 3.01372, Nature structural & molecular biology, 2012, Shu, Chang et. al.

Structural–FunctionalStudies of Burkholderia cenocepacia d -Glycero-β- d -manno-heptose 7-Phosphate Kinase (HldA) andCharacterization of Inhibitors with Antibiotic Adjuvant and AntivirulenceProperties
score: 3.0122321, Journal of Medicinal Chemistry, 2012, Lee, Ting-Wai et. al.

Structural characterization of the H-NS protein from Xylella fastidiosa and its interaction with DNA
score: 3.0115949, Archives of Biochemistry and Biophysics, 2012, Rosselli-Murai, Luciana K. et. al.

Further Insight into Substrate Recognition by USP7: Structural and Biochemical Analysis of the HdmX and Hdm2 Interactions with USP7
score: 3.0099338, Journal of Molecular Biology, 2010, Sarkari, Feroz et. al.

Preliminary crystallographic analysis of 4-oxalocrotonate tautomerase reveals the oligomeric structure of the enzyme
score: 3.0092692, Journal of Molecular Biology, 1994, Roper, David I. et. al.

Automation of NMR structure determination of proteins
score: 3.0037263, Current Opinion in Structural Biology, 2004, Altieri, Amanda S; Byrd, R Andrew

The C2 Domain of PKCδ Is a Phosphotyrosine Binding Domain
score: 3.0017047, Cell, 2005, Benes, Cyril H. et. al.

Visualizing the ATPase Cycle in a Protein Disaggregating Machine: Structural Basis for Substrate Binding by ClpB
score: 3.0000722, Molecular Cell, 2007, Lee, Sukyeong; Choi, Jae-Mun; Tsai, Francis T.F.

Molecular replacement in P450 crystal structure determinations
score: 2.9975755, Methods in Enzymology, 2002, Li, Huiying; Yano, Jason K.; Poulos, Thomas L.

Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
score: 2.9973301, Journal of Structural Biology, 2012, Zeytuni, Natalie; Baran, Dror; Davidov, Geula; Zarivach, Raz

Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
score: 2.9973301, Journal of Structural Biology, 2012, Zeytuni, Natalie; Baran, Dror; Davidov, Geula; Zarivach, Raz

Crystal structure of the β2 adrenergic receptor-Gs protein complex.
score: 2.9958085, Nature, 2011, Rasmussen, Søren G F et. al.

X-Ray Crystallographic Structure Determination of Large Asymmetric Macromolecular Assemblies
score: 2.99537, Methods in Enzymology, 2003, Abrahams, Jan Pieter; Ban, Nenad

Structural and Phylogenetic Analysis of Rhodobacter capsulatus NifF: Uncovering General Features of Nitrogen-fixation ( nif )-Flavodoxins
score: 2.9949019, International Journal of Molecular Sciences, 2013, Pérez-Dorado, Inmaculada et. al.

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket.
score: 2.992477, Nature, 2011, Nakashima, Ryosuke et. al.

Crystallographic studies of DNA and RNA
score: 2.9917792, Methods, 2009, Mooers, Blaine H.M.

Super-resolution biomolecular crystallography with low-resolution data.
score: 2.9913336, Nature, 2010, Schröder, Gunnar F; Levitt, Michael; Brunger, Axel T

Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex.
score: 2.9908625, Proceedings of the National Academy of Sciences of the United States of America, 2010, Kobayashi, Kan et. al.

Structural Basis for Different Specificities of Acyltransferases Associated with the Human Cytosolic and Mitochondrial Fatty Acid Synthases
score: 2.9907091, Chemistry & Biology, 2009, Bunkoczi, Gabor et. al.

Utilising Structural Knowledge in Drug Design Strategies: Applications Using Relibase † † We dedicate this paper to Professor J. D. Dunitz on the occasion of his 80th birthday.
score: 2.9900265, Journal of Molecular Biology, 2003, Günther, Judith et. al.

Determination of the NMR solution structure of the Hoechst 33258-d(GTGGAATTCCAC) 2 complex and comparison with the X-ray crystal structure
score: 2.9898627, Structure, 1993, Fede, Agostino et. al.

Knottin cyclization: impact on structure and dynamics
score: 2.989139, BMC Structural Biology, 2008, Heitz, Annie et. al.

Crystal structure of 1,3Gal43A, an exo-β-1,3-galactanase from Clostridium thermocellum
score: 2.9869817, Journal of Structural Biology, 2012, Jiang, Daohua et. al.

Crystal structure of 1,3Gal43A, an exo-β-1,3-galactanase from Clostridium thermocellum
score: 2.9869817, Journal of Structural Biology, 2012, Jiang, Daohua et. al.

Crystal structure of 1,3Gal43A, an exo-β-1,3-galactanase from Clostridium thermocellum
score: 2.9869817, Journal of Structural Biology, 2012, Jiang, Daohua et. al.

Solution Structure and Sugar-Binding Mechanism of Mouse Latrophilin-1 RBL: a 7TM Receptor-Attached Lectin-Like Domain
score: 2.9857793, Structure (London, England : 1993), 2008, Vakonakis, Ioannis et. al.

A 7 µm mini-beam improves diffraction data from small or imperfect crystals of macromolecules
score: 2.9845059, Acta Crystallographica Section D: Biological Crystallography, 2008, Sanishvili, Ruslan et. al.

Y-Family Polymerase Conformation Is a Major Determinant of Fidelity and Translesion Specificity
score: 2.9827312, Structure, 2013, Wilson, Ryan C.; Jackson, Meghan A.; Pata, Janice D.

Hydrogen bond stereochemistry in protein structure and function
score: 2.9826564, Journal of Molecular Biology, 1990, Ippolito, Joseph A. et. al.

Analysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR dimerization.
score: 2.9821753, Molecular and cellular biology, 2005, Ibrahimi, Omar A et. al.

Structural insights into small RNA sorting and mRNA target binding by Arabidopsis Argonaute Mid domains
score: 2.9802951, FEBS Letters, 2012, Zha, Xingfu; Xia, Qingyou; Adam Yuan, Y.

Crystal structure of a major seed storage protein, 11S proglobulin, from Amaranthus hypochondriacus: Insight into its physico-chemical properties
score: 2.9782954, Food Chemistry, 2012, Tandang-Silvas, Mary Rose et. al.

Structure of Gentlyase, the neutral metalloprotease of Paenibacillus polymyxa
score: 2.9771202, Acta Crystallographica Section D: Biological Crystallography, 2012, Ruf, Armin et. al.

The cytoplasmic coiled-coil mediates cooperative gating temperature sensitivity in the voltage-gated H(+) channel Hv1.
score: 2.9757482, Nature communications, 2012, Fujiwara, Yuichiro et. al.

Solution structure of Jingzhaotoxin-III, a peptide toxin inhibiting both Na v1.5 and K v2.1 channels
score: 2.9756408, Toxicon, 2007, Liao, Zhi et. al.

Conformational changes in serpins: I. the native and cleaved conformations of α 1-antitrypsin 1 1 Edited by J. M. Thornton
score: 2.9736651, Journal of Molecular Biology, 2000, Whisstock, James C et. al.

Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with Torpedo californica acetylcholinesterase.
score: 2.9732141, Protein science : a publication of the Protein Society, 2012, Paz, Aviv et. al.

Structure of the Human Protein Kinase MPSK1 Reveals an Atypical Activation Loop Architecture
score: 2.9732082, Structure, 2008, Eswaran, Jeyanthy et. al.

Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation
score: 2.9716383, Biochemical Journal, 2012, Boehringer, Jonas et. al.

Large Conformational Changes in a Kinesin Motor Catalyzed by Interaction with Microtubules
score: 2.9713677, Molecular Cell, 2006, Hirose, Keiko et. al.

Structure of the Guanine Nucleotide Exchange Factor Sec7 Domain of Human Arno and Analysis of the Interaction with ARF GTPase
score: 2.9713223, Cell, 1998, Mossessova, Elena; Gulbis, Jacqueline M.; Goldberg, Jonathan

Comparative biophysical characterization of chicken β2-microglobulin
score: 2.9706276, Biophysical Chemistry, 2012, Hee, Chee-Seng et. al.

Comparative biophysical characterization of chicken β2-microglobulin
score: 2.9706276, Biophysical Chemistry, 2012, Hee, Chee-Seng et. al.

Comparative biophysical characterization of chicken β2-microglobulin
score: 2.9706276, Biophysical Chemistry, 2012, Hee, Chee-Seng et. al.

The stability and dynamics of ribosomal protein L9: investigations of a molecular strut by amide proton exchange and circular dichroism 1 1 Edited by K. Nagai
score: 2.9702272, Journal of Molecular Biology, 1997, Lillemoen, Jarle; Cameron, Christopher S.; Hoffman, David W.

The Structure of an Unconventional HD-GYP Protein from Bdellovibrio Reveals the Roles of Conserved Residues in this Class of Cyclic-di-GMP Phosphodiesterases
score: 2.96866, mBio, 2011, Lovering, Andrew L. et. al.

Binding affinity difference induced by the stereochemistry of the sulfoxide bridge of the cyclic peptide inhibitors of Grb2-SH2 domain: NMR studies for the structural origin
score: 2.9685857, Biochemical and Biophysical Research Communications, 2005, Shi, Yan-hong et. al.

Proteins that bind high-mannose sugars of the HIV envelope
score: 2.9673625, Progress in Biophysics and Molecular Biology, 2005, Botos, Istvan; Wlodawer, Alexander

Specific interactions of sticholysin I with model membranes: an NMR study.
score: 2.9671497, Proteins, 2010, Castrillo, Inés et. al.

Isolation, kinetic analysis, and structural characterization of an antibody targeting the Bacillus anthracis major spore surface protein BclA.
score: 2.966841, Proteins, 2011, Nuttall, Stewart D et. al.

The structure and dynamics in solution of Cu(I) pseudoazurin from Paracoccus pantotrophus.
score: 2.9666148, Protein science : a publication of the Protein Society, 2000, Thompson, G S et. al.

TOUCHSTONEX: protein structure prediction with sparse NMR data.
score: 2.9645774, Proteins, 2003, Li, Wei et. al.

High resolution structures of the 4–4-20 Fab-fluorescein complex in two solvent systems: effects of solvent on structure and antigen-binding affinity
score: 2.9641956, Biophysical Journal, 1994, Herron, J.N. et. al.

The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin.
score: 2.9641234, Proteins, 1997, Tsai, F T et. al.

Structure of the Parathyroid Hormone Receptor C Terminus Bound to the G-Protein Dimer Gβ 1γ 2
score: 2.9634497, Structure, 2008, Johnston, Christopher A. et. al.

Local and global interpretations of a disease causing mutation near the ligand entry path in hyperpolarization-activated cAMP-gated (HCN) channel
score: 2.9625082, Structure, 2012, Xu, Xinping et. al.

X-Ray Crystallography of Antibodies
score: 2.9624472, Advances in Protein Chemistry, 1996, Padlan, Eduardo A.

GGA autoinhibition revisited.
score: 2.9621483, Traffic (Copenhagen, Denmark), 2010, Cramer, Jacob F et. al.

The Concerted Conformational Changes during Human Rhinovirus 2 Uncoating
score: 2.9616543, Molecular Cell, 2002, Hewat, Elizabeth A; Neumann, Emmanuelle; Blaas, Dieter

The Concerted Conformational Changes during Human Rhinovirus 2 Uncoating
score: 2.9616543, Molecular Cell, 2002, Hewat, Elizabeth A; Neumann, Emmanuelle; Blaas, Dieter

Structural Mechanism of GAF-Regulated σ54Activators fromAquifex aeolicus
score: 2.9597141, Journal of Molecular Biology, 2013, Batchelor, Joseph D. et. al.

Potential double-flipping mechanism by E. coli MutY
score: 2.959694, Progress in Nucleic Acid Research and Molecular Biology, 2001, House, Paul G et. al.

Potential double-flipping mechanism by E. coli MutY
score: 2.959694, Progress in Nucleic Acid Research and Molecular Biology, 2001, House, Paul G et. al.

Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9)
score: 2.9590903, Nucleic Acids Research, 2013, Fu, Qinqin; Yuan, Y. Adam

High-throughput crystallography for structural genomics
score: 2.9584191, Current Opinion in Structural Biology, 2009, Joachimiak, Andrzej

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy
score: 2.9575288, Molecular Cell, 2012, von Muhlinen, Natalia et. al.

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy
score: 2.9575288, Molecular Cell, 2012, von Muhlinen, Natalia et. al.

Determining membrane protein structures: still a challenge!
score: 2.9573008, Trends in Biochemical Sciences, 2007, Lacapère, Jean-Jacques et. al.

Biophysical and Bioinformatic Analyses Implicate the Treponema pallidum Tp34 Lipoprotein (Tp0971) in Transition Metal Homeostasis.
score: 2.9572776, Journal of bacteriology, 2012, Brautigam, Chad A et. al.

Structural insights into the ligand binding domains of membrane bound guanylyl cyclases and natriuretic peptide receptors 1 1 Edited by P. E. Wright
score: 2.9562503, Journal of Molecular Biology, 2001, van den Akker, Focco

Structural Modes of Stabilization of Permissive Phosphorylation Sites in Protein Kinases: Distinct Strategies in Ser/Thr and Tyr Kinases
score: 2.9549591, Journal of Molecular Biology, 2004, Krupa, A.; Preethi, G.; Srinivasan, N.

Mutagenesis of Zinc Ligand Residue Cys221 Reveals Plasticity in the IMP-1 Metallo-β-Lactamase Active Site.
score: 2.9548632, Antimicrobial agents and chemotherapy, 2012, Horton, Lori B et. al.

Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains.
score: 2.9482282, Proceedings of the National Academy of Sciences of the United States of America, 2010, Ogura, Toshihiko et. al.

NMR spectroscopic investigations of the activated p38α mitogen-activated protein kinase.
score: 2.9474656, Chembiochem : a European journal of chemical biology, 2011, Nielsen, Gerd; Schwalbe, Harald

Novel alpha- and beta-amino acid inhibitors of influenza virus neuraminidase.
score: 2.9470058, Antimicrobial agents and chemotherapy, 2001, Kati, W M et. al.

Discovery of substituted N-phenylbenzenesulphonamides as a novel class of non-nucleoside hepatitis C virus polymerase inhibitors
score: 2.9454611, Antiviral Research, 2012, May, Marina M. et. al.

Discovery of substituted N-phenylbenzenesulphonamides as a novel class of non-nucleoside hepatitis C virus polymerase inhibitors
score: 2.9454611, Antiviral Research, 2012, May, Marina M. et. al.

Specific DNA-RNA Hybrid Recognition by TAL Effectors
score: 2.9448576, Cell Reports, 2012, Yin, Ping et. al.

Specific DNA-RNA Hybrid Recognition by TAL Effectors
score: 2.9448576, Cell Reports, 2012, Yin, Ping et. al.

An Allosteric Inhibitor of Protein Arginine Methyltransferase 3
score: 2.944804, Structure, 2012, Siarheyeva, Alena et. al.

Structural insights of HutP-mediated regulation of transcription of the hut operon in Bacillus subtilis
score: 2.9445549, Biophysical Chemistry, 2007, Kumarevel, Thirumananseri

Systematic Comparison of Crystal and NMR Protein Structures Deposited in the Protein Data Bank
score: 2.9441022, The Open Biochemistry Journal, 2010, Sikic, Kresimir; Tomic, Sanja; Carugo, Oliviero

Ribose and glucose-galactose receptors
score: 2.9419212, Journal of Molecular Biology, 1992, Mowbray, Sherry L.

Refined 2·0 Å X-ray Crystal Structure of the Snake Venom Zinc-endopeptidase Adamalysin II
score: 2.9407392, Journal of Molecular Biology, 1994, Gomis-Rüth, F.X. et. al.

(NZ)CH...O Contacts assist crystallization of a ParB-like nuclease
score: 2.9398505, BMC Structural Biology, 2007, Shaw, Neil et. al.

Alpha-1 Giardin is an Annexin with Highly Unusual Calcium-Regulated Mechanisms
score: 2.9387445, Journal of Molecular Biology, 2012, Weeratunga, Saroja K. et. al.

Mutational Analysis of the Uracil DNA Glycosylase Inhibitor Protein and Its Interaction with Escherichia coli Uracil DNA Glycosylase
score: 2.9385407, Journal of Molecular Biology, 2002, Acharya, Narottam; Roy, Sudipta; Varshney, Umesh

XtalView, protein structure solution and protein graphics, a short history
score: 2.937912, Journal of Structural Biology, 2008, McRee, Duncan E.; Israel, Mark

Proton nuclear magnetic resonance assignments and structural characterization of an intramolecular DNA triplex
score: 2.9377359, Journal of Molecular Biology, 1992, Macaya, Román et. al.

Binding of Rabies Virus Polymerase Cofactor to Recombinant Circular Nucleoprotein–RNA Complexes
score: 2.9358878, Journal of Molecular Biology, 2009, Ribeiro, Euripedes de Almeida et. al.

PKA: a portrait of protein kinase dynamics
score: 2.9337902, BBA - Proteins and Proteomics, 2004, Taylor, S.S. et. al.

Crystal structures from the Plasmodium peroxiredoxins: new insights into oligomerization and product binding
score: 2.9336344, BMC Structural Biology, 2012, Qiu, Wei et. al.

Protein tyrosine phosphatases: structure-function relationships.
score: 2.9334944, The FEBS journal, 2008, Tabernero, Lydia et. al.

Determinants for substrate specificity of the bacterial PP2C protein phosphatase tPphA from Thermosynechococcus elongatus.
score: 2.9330962, The FEBS journal, 2011, Su, Jiyong; Forchhammer, Karl

Engineering monomeric streptavidin and its ligands with infinite affinity in binding but reversibility in interaction.
score: 2.9324451, Proteins, 2009, Wu, Sau-Ching; Ng, Kenneth K-S; Wong, Sui-Lam

Validation of NMR side-chain conformations by packing calculations.
score: 2.9323443, Proteins, 1999, Chung, S Y; Subbiah, S

Solution structure of Grb2 reveals extensive flexibility necessary for target recognition 1 1 Edited by P. E. Wright
score: 2.9315956, Journal of Molecular Biology, 2001, Yuzawa, Satoru et. al.

RNA recognition by the human U1A protein is mediated by a network of local cooperative interactions that create the optimal binding surface 1 1 Edited by D. E. Draper
score: 2.9308717, Journal of Molecular Biology, 1999, Kranz, James K.; Hall, Kathleen B.

Two structurally different RNA molecules are bound by the spliceosomal protein U1A using the same recognition strategy
score: 2.9304696, Structure, 1996, Jovine, Luca et. al.

Renin inhibition by substituted piperidines: A novel paradigm for the inhibition of monomeric aspartic proteinases?
score: 2.9302026, Chemistry & Biology, 1999, Oefner, C et. al.

Visualizing group II intron catalysis through the stages of splicing
score: 2.9293629, Cell, 2012, Marcia, Marco; Pyle, Anna Marie

Structure of leech derived tryptase inhibitor (LDTI-C) in solution
score: 2.927399, FEBS Letters, 1994, Mühlhahn, Peter et. al.

Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function
score: 2.9273538, Cell Reports, 2012, Song, Xiaomin et. al.

Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function
score: 2.9273538, Cell Reports, 2012, Song, Xiaomin et. al.

Conformational changes in serpins: I. the native and cleaved conformations of α 1-antitrypsin 1 1 Edited by J. M. Thornton
score: 2.9254152, Journal of Molecular Biology, 2000, Whisstock, James C et. al.

The NMR restraints grid at BMRB for 5,266 protein and nucleic acid PDB entries
score: 2.9226094, Journal of Biomolecular Nmr, 2009, Doreleijers, Jurgen F. et. al.

Crystal structure of an active form of RAS protein, a complex of a GTP analog and the HRAS p21 catalytic domain.
score: 2.9217177, Proceedings of the National Academy of Sciences of the United States of America, 1990, Brünger, A T et. al.

Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface
score: 2.9197475, Molecular Cell, 2012, Duda, David M. et. al.

Three-dimensional structure of human basic fibroblast growth factor.
score: 2.9195741, Proceedings of the National Academy of Sciences of the United States of America, 1991, Eriksson, A E; Cousens, L S; Weaver, L H; Matthews, B W

Structural basis of fumarate hydratase deficiency
score: 2.9191067, Journal of Inherited Metabolic Disease, 2011, Picaud, Sarah et. al.

Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases.
score: 2.9181155, The FEBS journal, 2009, Davis, Tara L et. al.

Structural and functional study of a conserved region in the uncoupling protein UCP1: the three matrix loops are involved in the control of transport 1 1 Edited by R. Huber
score: 2.9134233, Journal of Molecular Biology, 1999, González-Barroso, M.Mar et. al.

Carboxyl p K a Values, Ion Pairs, Hydrogen Bonding, and the pH-dependence of Folding the Hyperthermophile Proteins Sac7d and Sso7d
score: 2.9130016, Journal of Molecular Biology, 2007, Clark, Andrew T. et. al.

Host-selected amino acid changes at the sialic acid binding pocket of the parvovirus capsid modulate cell binding affinity and determine virulence.
score: 2.9124142, Journal of virology, 2006, López-Bueno, Alberto et. al.

Solution properties of the archaeal CRISPR DNA repeat-binding homeodomain protein Cbp2
score: 2.9119173, Nucleic Acids Research, 2013, Kenchappa, Chandra S. et. al.

NMR spectroscopy of G-quadruplexes
score: 2.9116315, Methods, 2012, Adrian, Michael; Heddi, Brahim; Phan, Anh Tuân

Identification of Functionally Conserved Regions in the Structure of the Chaperone/CenH3/H4 Complex
score: 2.9110962, Journal of Molecular Biology, 2013, Hong, Jingjun et. al.

Two-Crystal Structures of Tropomyosin C-Terminal Fragment 176–273: Exposure of the Hydrophobic Core to the Solvent Destabilizes the Tropomyosin Molecule
score: 2.911035, Biophysical Journal, 2008, Minakata, Shiho et. al.

Purine nucleoside phosphorylases: properties, functions, and clinical aspects
score: 2.9098534, Pharmacology and Therapeutics, 2000, Bzowska, Agnieszka; Kulikowska, Ewa; Shugar, David

Three-dimensional solution structure of apo-neocarzinostatin
score: 2.908937, Journal of Molecular Biology, 1992, Gao, Xiaolian

An NMR strategy for fragment-based ligand screening utilizing a paramagnetic lanthanide probe
score: 2.9074071, Journal of Biomolecular Nmr, 2011, Saio, Tomohide et. al.

1 Finding Protein Kinase Hits using Structural Information
score: 2.9065028, Progress in Medicinal Chemistry, 2006, Cherry, Mike; Reader, John; Williams, David

Beta-hairpin formation in aqueous solution and in the presence of trifluoroethanol: a (1)H and (13)C nuclear magnetic resonance conformational study of designed peptides.
score: 2.9051134, Biopolymers, 2005, Santiveri, Clara M et. al.

Role of Trp19 and Tyr200 in catalysis by the γ-class carbonic anhydrase fromMethanosarcina thermophila
score: 2.8983068, Archives of Biochemistry and Biophysics, 2013, Zimmerman, Sabrina et. al.

Role of Trp19 and Tyr200 in catalysis by the γ-class carbonic anhydrase from Methanosarcina thermophila
score: 2.8983068, Archives of Biochemistry and Biophysics, 2013, Zimmerman, Sabrina et. al.

Structural comparison of the poplar plastocyanin isoforms PCa and PCb sheds new light on the role of the copper site geometry in interactions with redox partners in oxygenic photosynthesis
score: 2.8972534, Journal of Inorganic Biochemistry, 2012, Kachalova, Galina S. et. al.

Amine free crystal structure: The crystal structure of d(CGCGCG) 2 and methylamine complex crystal
score: 2.8964003, Biochemical and Biophysical Research Communications, 2006, Ohishi, Hirofumi et. al.

Inhibitors of proteases and amide hydrolases that employ an α-ketoheterocycle as a key enabling functionality
score: 2.896059, Bioorganic & Medicinal Chemistry, 2008, Maryanoff, Bruce E.; Costanzo, Michael J.

Structural evolution of the membrane-coating module of the nuclear pore complex.
score: 2.8927065, Proceedings of the National Academy of Sciences of the United States of America, 2012, Liu, Xiaoping et. al.

Structural basis for potent inhibition of the Aurora kinases and a T315I multi-drug resistant mutant form of Abl kinase by VX-680
score: 2.8922117, Cancer Letters, 2007, Cheetham, G.M.T. et. al.

Synthesis, SAR study, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase (FAAH) inhibitors
score: 2.8916671, Bioorganic & Medicinal Chemistry, 2013, Kono, Mitsunori et. al.

Dimer structure of magainin 2 bound to phospholipid vesicles.
score: 2.8908624, Biopolymers, 2002, Wakamatsu, Kaori et. al.

Assembly of the Complex between Archaeal RNase P Proteins RPP30 and Pop5
score: 2.8906239, Archaea, 2011, Crowe, Brandon L. et. al.

Structure, function, and evolution of the Crimean-Congo hemorrhagic fever virus nucleocapsid protein.
score: 2.8902073, Journal of virology, 2012, Carter, Stephen D et. al.

A Mechanism for Histone Chaperoning Activity of Nucleoplasmin: Thermodynamic and Structural Models
score: 2.8888517, Journal of Molecular Biology, 2009, Taneva, Stefka G. et. al.

Different catalytic properties of two highly homologous triosephosphate isomerase monomers
score: 2.8886337, Biochemical and Biophysical Research Communications, 2009, Zárate-Pérez, Francisco et. al.

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.
score: 2.8884963, Nature, 2012, Armstrong, Anthony A; Mohideen, Firaz; Lima, Christopher D

Substrate-Induced Change in the Quaternary Structure of Type 2 Isopentenyl Diphosphate Isomerase from Sulfolobus shibatae.
score: 2.8869201, Journal of bacteriology, 2012, Nakatani, Hitomi et. al.

1 Finding Protein Kinase Hits using Structural Information
score: 2.886729, Progress in Medicinal Chemistry, 2006, Cherry, Mike; Reader, John; Williams, David

Crystal structure of the Kar3-like kinesin motor domain from the filamentous fungus Ashbya gossypii.
score: 2.8866442, Proteins, 2012, Duan, Da et. al.

Structure of an Insect Parvovirus ( Junonia coenia Densovirus) Determined by Cryo-electron Microscopy
score: 2.8861179, Journal of Molecular Biology, 2005, Bruemmer, Anneke et. al.

Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes
score: 2.885955, Chemistry & Biology, 1999, Lu, Wuyuan et. al.

Probing structural determinants specifying high thermostability in Bacillus licheniformis α-amylase 1 1 Edited by A. R. Fersht
score: 2.8852813, Journal of Molecular Biology, 2000, Declerck, Nathalie et. al.

1.8 Å X-ray structure of C95M/C1095F double mutant of tethered HIV-1 protease dimer complexed with acetyl pepstatin
score: 2.8840443, Biochemical and Biophysical Research Communications, 2004, Prashar, Vishal; Hosur, M.V.

Substrate-Selective Inhibition of Protein Kinase PDK1 by Small Compounds that Bind to the PIF-Pocket Allosteric Docking Site
score: 2.8835548, Chemistry & Biology, 2012, Busschots, Katrien et. al.

Crystal Structure of the 16 Heme Cytochrome from Desulfovibrio gigas: A Glycosylated Protein in a Sulphate-reducing Bacterium
score: 2.8830074, Journal of Molecular Biology, 2007, Santos-Silva, Teresa et. al.

The structure of alfalfa mosaic virus capsid protein assembled as a T=1 icosahedral particle at 4.0-A resolution.
score: 2.8829766, Journal of virology, 1997, Kumar, A et. al.

Duplex interrogation by a direct DNA repair protein in search of base damage.
score: 2.8829516, Nature structural & molecular biology, 2012, Yi, Chengqi et. al.

Fluctuations in ion pairs and their stabilities in proteins.
score: 2.8820242, Proteins, 2001, Kumar, S; Nussinov, R

Direct crystallographic observation of an acyl-enzyme intermediate in the elastase-catalyzed hydrolysis of a peptidyl ester substrate: Exploiting the “glass transition” in protein dynamics
score: 2.8819424, Bioorganic Chemistry, 2006, Ding, Xiaochun et. al.

Msl1-Mediated Dimerization of the Dosage Compensation Complex Is Essential for Male X-Chromosome Regulation in Drosophila
score: 2.8815633, Molecular Cell, 2012, Hallacli, Erinc et. al.

Msl1-Mediated Dimerization of the Dosage Compensation Complex Is Essential for Male X-Chromosome Regulation in Drosophila
score: 2.8815633, Molecular Cell, 2012, Hallacli, Erinc et. al.

Backbone dynamics of the regulatory domain of calcium vector protein, studied by (15)N relaxation at four fields, reveals unique mobility characteristics of the intermotif linker.
score: 2.8805417, Protein science : a publication of the Protein Society, 2001, Théret, I; Cox, J A; Mispelter, J; Craescu, C T

NMR evidence for differential phosphorylation-dependent interactions in WT and DeltaF508 CFTR.
score: 2.8791168, The EMBO journal, 2010, Kanelis, Voula et. al.

Ligand-Induced Conformational Rearrangements Promote Interaction between the Escherichia coli Enterobactin Biosynthetic Proteins EntE and EntB
score: 2.8790861, Journal of Molecular Biology, 2009, Khalil, Sofia; Pawelek, Peter D.

How Thioredoxin can Reduce a Buried Disulphide Bond
score: 2.878928, Journal of Molecular Biology, 2004, Messens, Joris et. al.

Rapid Assessment of Protein Structural Stability and Fold Validation via NMR
score: 2.878681, Methods in Enzymology, 2005, Hoffmann, Bernd et. al.

Rapid Assessment of Protein Structural Stability and Fold Validation via NMR
score: 2.878681, Methods in Enzymology, 2005, Hoffmann, Bernd et. al.

Polarizable Atomic Multipole X-Ray Refinement: Hydration Geometry and Application to Macromolecules
score: 2.8777401, Biophysical Journal, 2010, Fenn, Timothy D. et. al.

Mapping of the Interaction Interface of DNA Polymerase β with XRCC1
score: 2.8764315, Structure, 2002, Gryk, Michael R. et. al.

NMR Analysis of the Conformational Properties of the Trapped on-pathway Folding Intermediate of the Bacterial Immunity Protein Im7
score: 2.8747813, Journal of Molecular Biology, 2007, Whittaker, Sara B.-M. et. al.

DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O 6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy
score: 2.8739698, DNA Repair, 2007, Tubbs, Julie L.; Pegg, Anthony E.; Tainer, John A.

Electrostatic stabilization of a thermophilic cold shock protein 1 1 Edited by C. R. Matthews
score: 2.873663, Journal of Molecular Biology, 2001, Perl, Dieter; Schmid, Franz X.

Mechanism for Template-Independent Terminal Adenylation Activity of Qβ Replicase
score: 2.8735715, Structure, 2012, Takeshita, Daijiro; Yamashita, Seisuke; Tomita, Kozo

Mechanism for Template-Independent Terminal Adenylation Activity of Qβ Replicase
score: 2.8735715, Structure, 2012, Takeshita, Daijiro; Yamashita, Seisuke; Tomita, Kozo

Structure and Disorder in an Unfolded State under Nondenaturing Conditions from Ensemble Models Consistent with a Large Number of Experimental Restraints
score: 2.8725646, Journal of Molecular Biology, 2009, Marsh, Joseph A.; Forman-Kay, Julie D.

Inhibition of the complete set of mammalian secreted phospholipases A 2 by indole analogues
score: 2.8725478, Bioorganic & Medicinal Chemistry, 2004, Smart, Brian P. et. al.

The three-dimensional structure of the analgesic α-conotoxin, RgIA
score: 2.8723884, FEBS Letters, 2008, Clark, Richard J. et. al.

Structure of the GcpE (IspG)–MEcPP complex from Thermus thermophilus
score: 2.8716093, FEBS Letters, 2012, Rekittke, Ingo; Jomaa, Hassan; Ermler, Ulrich

Solution structure of a zinc-finger domain that binds to poly-ADP-ribose.
score: 2.8705364, Genes to cells : devoted to molecular & cellular mechanisms, 2010, Isogai, Shin et. al.

Crystal structures of human CDY proteins reveal a crotonase-like fold.
score: 2.8701773, Proteins, 2009, Wu, Hong et. al.

Bcl-xl does not have to bind Bax to protect T cells from death
score: 2.8688549, The Journal of Experimental Medicine, 2006, Liu, Xinqi et. al.

Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein
score: 2.8682819, Cell, 1994, Matthews, David A. et. al.

Structural Basis for theActivation of Platelet IntegrinαIIbβ3 by Calcium- and Integrin-Binding Protein 1
score: 2.8655225, Journal of the American Chemical Society, 2012, Huang, Hao; Vogel, Hans J.

Curling of Flap Tips in HIV-1 Protease as a Mechanism for Substrate Entry and Tolerance of Drug Resistance
score: 2.8654821, Structure, 2000, Scott, Walter R.P; Schiffer, Celia A

MS-271, A novel inhibitor of calmodulin-activated myosin light chain kinase from Streptomyces sp.—II. Solution structure of MS-271: Characteristic features of the ‘lasso’ structure
score: 2.8649358, Bioorganic & Medicinal Chemistry, 1996, Katahira, Ritsuko et. al.

Reprint of “Crystal structure of chemically synthesized HIV-1 protease and a ketomethylene isostere inhibitor based on the p2/NC cleavage site” [Bioorg. Med. Chem. Lett. 18 (2008) 4554-4557]
score: 2.8644844, Bioorganic & Medicinal Chemistry Letters, 2008, Torbeev, Vladimir Yu. et. al.

Backbone dynamics of the C-terminal SH2 domain of the p85α subunit of phosphoinositide 3-kinase: effect of phosphotyrosine-peptide binding and characterization of slow conformational exchange processes 1 1 Edited by P. E. Wright
score: 2.8642382, Journal of Molecular Biology, 2000, Kristensen, Søren M. et. al.

Kinetic and Crystallographic Studies of Extended-Spectrum GES-11, GES-12, and GES-14 β-Lactamases.
score: 2.8629056, Antimicrobial agents and chemotherapy, 2012, Delbrück, Heinrich et. al.

RETRACTED: Crystal structure of dengue virus NS3 protease in complex with a bowman-birk inhibitor: implications for flaviviral polyprotein processing and drug design 1 1 Edited by I. Wilson
score: 2.8599669, Journal of Molecular Biology, 2000, Krishna Murthy, H.M; Judge, K; DeLucas, L; Padmanabhan, R

NMR analysis of the binding of a rhodanese peptide to a minichaperone in solution 1 1 Edited by J. Karn
score: 2.8584457, Journal of Molecular Biology, 1999, Kobayashi, Naohiro et. al.

Accurate and rapid docking of protein-protein complexes on the basis of intermolecular nuclear overhauser enhancement data and dipolar couplings by rigid body minimization.
score: 2.8583862, Proceedings of the National Academy of Sciences of the United States of America, 2000, Clore, G M

The Crystal Structure of the Extracellular 11-heme Cytochrome UndA Reveals a Conserved 10-heme Motif and Defined Binding Site for Soluble Iron Chelates
score: 2.8583487, Structure, 2012, Edwards, Marcus J. et. al.

The Structure of the PapD-PapGII Pilin Complex Reveals an Open and Flexible P5 Pocket.
score: 2.8573534, Journal of bacteriology, 2012, Ford, Bradley et. al.

Evolutionary Genomics of the HAD Superfamily: Understanding the Structural Adaptations and Catalytic Diversity in a Superfamily of Phosphoesterases and Allied Enzymes
score: 2.8568503, Journal of Molecular Biology, 2006, Burroughs, A. Maxwell et. al.

The Backrub Motion: How Protein Backbone Shrugs When a Sidechain Dances
score: 2.8563973, Structure, 2006, Davis, Ian W. et. al.

HsdR Subunit of the Type I Restriction-Modification Enzyme EcoR124I: Biophysical Characterisation and Structural Modelling
score: 2.8537982, Journal of Molecular Biology, 2008, Obarska-Kosinska, Agnieszka et. al.

Ensemble Structure of the Modular and Flexible Full-Length Vesicular Stomatitis Virus Phosphoprotein
score: 2.8530918, Journal of Molecular Biology, 2012, Leyrat, Cédric et. al.

The Structural Basis of Macrolide–Ribosome Binding Assessed Using Mutagenesis of 23 S rRNA Positions 2058 and 2059
score: 2.8530096, Journal of Molecular Biology, 2004, Pfister, Peter et. al.

A picornaviral loop-to-loop replication complex
score: 2.8521903, Journal of Structural Biology, 2009, Claridge, Jolyon K. et. al.

NMR Studies of the C-Terminus of alpha4 Reveal Possible Mechanism of Its Interaction with MID1 and Protein Phosphatase 2A
score: 2.8518711, PLoS ONE, 2011, Du, Haijuan; Massiah, Michael A.

The structural interpretations of residue Ser 297 in catalytic efficiency of Escherichia coli phenylalanine aminotransferase
score: 2.8511227, BBA - Proteins and Proteomics, 2003, Wu, Szu-Pei et. al.

Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases.
score: 2.8511195, Proceedings of the National Academy of Sciences of the United States of America, 2007, Yu, Xiao et. al.

Order–Disorder–Order Transitions Mediate the Activation of Cholera Toxin
score: 2.8509762, Journal of Molecular Biology, 2008, Ampapathi, Ravi S. et. al.

Structure and function of cytochromes P450:a comparative analysis of three crystal structures
score: 2.8490658, Structure, 1995, Hasemann, Charles A et. al.

Hydration and solution structure of d(CGCAAATTTGCG) 2 and its complex with propamidine from NMR and molecular modelling
score: 2.8487562, BBA - Gene Structure and Expression, 1997, Lane, Andrew N; Jenkins, Terence C; Frenkiel, Thomas A

Solution structure of the phosphocarrier protein HPr from Bacillus subtilis by two-dimensional NMR spectroscopy.
score: 2.8482903, Protein science : a publication of the Protein Society, 1992, Wittekind, M et. al.

The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B
score: 2.8468903, Archives of Biochemistry and Biophysics, 2012, Brandão, Tiago A.S.; Johnson, Sean J.; Hengge, Alvan C.

The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B
score: 2.8468903, Archives of Biochemistry and Biophysics, 2012, Brandão, Tiago A.S.; Johnson, Sean J.; Hengge, Alvan C.

Crystal structure of a Cas6 paralogous protein from Pyrococcus furiosus.
score: 2.8463109, Proteins, 2012, Park, Hye-Mi et. al.

Structure and Inhibition of the SARS Coronavirus Envelope Protein Ion Channel
score: 2.8453775, PLoS Pathogens, 2009, Pervushin, Konstantin et. al.

Structure and Dynamics of Pin1 During Catalysis by NMR
score: 2.8446712, Journal of Molecular Biology, 2007, Labeikovsky, Wladimir et. al.

Crystallization data mining in structural genomics: using positive and negative results to optimize protein crystallization screens
score: 2.8387793, Methods, 2004, Page, Rebecca; Stevens, Raymond C.

Cofactor-binding sites in proteins of deviating sequence: Comparative analysis and clustering in torsion angle, cavity, and fold space.
score: 2.8387223, Proteins, 2011, Stegemann, Björn; Klebe, Gerhard

NMR Structure and Mutagenesis of the N-Terminal Dbl Homology Domain of the Nucleotide Exchange Factor Trio
score: 2.8386755, Cell, 1998, Liu, Xiaohong et. al.

Water molecules in DNA recognition I: hydration lifetimes of trp operator DNA in solution measured by NMR spectroscopy 1 1 Edited by B. Honig
score: 2.8375454, Journal of Molecular Biology, 1998, Sunnerhagen, Maria et. al.

Crystal Structure of Pseudomonas aeruginosa Tsi2 Reveals a Stably Folded Superhelical Antitoxin
score: 2.8369314, Journal of Molecular Biology, 2012, Zou, Tingting et. al.

Structures of larger proteins, protein-ligand and protein-DNA complexes by multi-dimensional heteronuclear NMR
score: 2.8367607, Progress in Biophysics and Molecular Biology, 1994, Marius Clore, G.; Gronenborn, Angela M.

NMR Structural Characterization of Substrates Bound to N-Acetylglucosaminyltransferase V
score: 2.835686, Journal of Molecular Biology, 2007, Macnaughtan, Megan A. et. al.

The impact of CRISPR repeat sequence on structures of a Cas6 protein-RNA complex.
score: 2.8355431, Protein science : a publication of the Protein Society, 2012, Wang, Ruiying et. al.

Tryptophan- and arginine-rich antimicrobial peptides: Structures and mechanisms of action
score: 2.8351683, BBA - Biomembranes, 2006, Chan, David I.; Prenner, Elmar J.; Vogel, Hans J.

Determination of the positions of bound water molecules in the solution structure of reduced human thioredoxin by heteronuclear three-dimensional nuclear magnetic resonance spectroscopy
score: 2.8346044, Journal of Molecular Biology, 1991, Forman-Kay, Julie D. et. al.

Structural and functional characterization of the two phosphoinositide binding sites of PROPPINs, a β-propeller protein family.
score: 2.8343561, Proceedings of the National Academy of Sciences of the United States of America, 2012, Krick, Roswitha et. al.

Dissection of the Network of Interactions That Links RNA Processing with Glycolysis in the Bacillus subtilis Degradosome
score: 2.8332495, Journal of Molecular Biology, 2012, Newman, Joseph A. et. al.

The Three-dimensional Structure of Genomic RNA in Bacteriophage MS2: Implications for Assembly
score: 2.8332146, Journal of Molecular Biology, 2008, Toropova, Katerina et. al.

A multi-dataset data-collection strategy produces better diffraction data
score: 2.8319153, Acta Crystallographica Section A: Foundations of Crystallography, 2011, Liu, Zhi-Jie et. al.

Structural and Functional Insight into ADF/Cofilin from Trypanosoma brucei
score: 2.8316048, PLoS ONE, 2013, Dai, Kun et. al.

Solving the Structure of PTB in Complex with Pyrimidine Tracts: An NMR Study of Protein–RNA Complexes of Weak Affinities†
score: 2.8306327, Journal of Molecular Biology, 2007, Auweter, Sigrid D. et. al.

NMR structure determination of the Escherichia coli DnaJ molecular chaperone: secondary structure and backbone fold of the N-terminal region (residues 2-108) containing the highly conserved J domain.
score: 2.8299035, Proceedings of the National Academy of Sciences of the United States of America, 1994, Szyperski, T et. al.

Crystallographic investigation of the dependence of calcium and phosphate ions for notexin
score: 2.8298525, FEBS Letters, 1997, Westerlund, Bengt et. al.

Crystallographic investigation of the dependence of calcium and phosphate ions for notexin
score: 2.8298525, FEBS Letters, 1997, Westerlund, Bengt et. al.

Molecular and structural biology of bleomycin and its resistance determinants
score: 2.8296812, Journal of Bioscience and Bioengineering, 2002, Sugiyama, Masanori; Kumagai, Takanori

Temperature-dependence of protein hydrogen bond properties as studied by high-resolution NMR 1 1 Edited by P. E. Wright
score: 2.8293413, Journal of Molecular Biology, 2002, Cordier, Florence; Grzesiek, Stephan

Duplex Interrogation by a Direct DNA Repair Protein in Search of Base Damage
score: 2.8291208, Nature structural & molecular biology, 2012, Yi, Chengqi et. al.

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain.
score: 2.8275582, Proceedings of the National Academy of Sciences of the United States of America, 2008, Wells, Mark et. al.

Solubility engineering and crystallization of human apolipoprotein D.
score: 2.8274494, Protein science : a publication of the Protein Society, 2006, Nasreen, Amber et. al.

Ligand-induced stabilization of PPARγ monitored by NMR spectroscopy: implications for nuclear receptor activation 1 1 Edited by P. E. Wright
score: 2.8272775, Journal of Molecular Biology, 2000, Johnson, Bruce A et. al.

Refined structure of the aminobenzolamide complex of human carbonic anhydrase II at 1.9Åand sulphonamide modelling of bovine carbonic anhydrase III
score: 2.8264842, International Journal of Biological Macromolecules, 1993, Vidgren, Jukka; Svensson, Anders; Liljas, Anders

Computational determination of the structure of rat fc bound to the neonatal fc receptor 1 1 Edited by I. A. Wilson
score: 2.826229, Journal of Molecular Biology, 1998, Weng, Zhiping et. al.

Conformational correlation and coupled motion between residue A21 and B25 side chain observed in crystal structures of insulin mutants at position A21
score: 2.8260726, Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology, 2000, Zeng, Zong-Hao et. al.

Structure and dynamics of the antitumor drugs nogalamycin and disnogalamycin complexed to d(CGTACG) 2: comparison of crystal and solution structures
score: 2.8218338, Gene, 1994, Robinson, Howard; Yang, Danzhou; Wang, Andrew H.-J.

Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules
score: 2.8217487, The EMBO Journal, 2012, van Weering, Jan R T et. al.

On the global architecture of initiation factor IF3: a comparative study of the linker regions from the Escherichia coli protein and the Bacillus stearothermophilus protein 1 1 Edited by P.E. Wright
score: 2.8214681, Journal of Molecular Biology, 1998, Hua, Yuxin; Raleigh, Daniel P.

Three-dimensional structure of the complex of guanylate kinase from yeast with its substrate GMP
score: 2.8208171, Journal of Molecular Biology, 1990, Stehle, Thilo; Schulz, Georg E.

Cytidine Deaminase. The 2·3 Å Crystal Structure of an Enzyme: Transition-state Analog Complex
score: 2.8203438, Journal of Molecular Biology, 1994, Betts, Laurie et. al.

Projection structure of the monomeric porin OmpG at 6 å resolution 1 1 Edited by W. Baumeister
score: 2.8193883, Journal of Molecular Biology, 2001, Behlau, Matthias et. al.

Structural Flexibility in Human Topoisomerase I Revealed in Multiple Non-isomorphous Crystal Structures
score: 2.8193835, Journal of Molecular Biology, 1999, Redinbo, Matthew R. et. al.

Unusual domain pairing in a mutant of bovine lens γB-crystallin 1 1 Edited by R. Huber
score: 2.8185554, Journal of Molecular Biology, 1998, Palme, Stefan; Jaenicke, Rainer; Slingsby, Christine

Structural reorganization of the interleukin-7 signaling complex.
score: 2.8174002, Proceedings of the National Academy of Sciences of the United States of America, 2012, McElroy, Craig A et. al.

Structural and Functional Analysis of the Complex between Citrate and the Zinc Peptidase Carboxypeptidase A
score: 2.8171689, Enzyme Research, 2011, Fernández, Daniel et. al.

The NECAP PHear domain increases clathrin accessory protein binding potential.
score: 2.8169649, The EMBO journal, 2007, Ritter, Brigitte et. al.

Influenza Neuraminidase as Target for Antivirals
score: 2.8167543, Advances in Virus Research, 1999, Air, Gillian M.; Ghate, Anita A.; Stray, Stephen J.

Simulations of apo and holo-fatty acid binding protein: structure and dynamics of protein, ligand and internal water 1 1 Edited by B. Honig
score: 2.8149633, Journal of Molecular Biology, 2002, Bakowies, Dirk; van Gunsteren, Wilfred F.

Does NMR Mean “Not for Molecular Replacement”? Using NMR-Based Search Models to Solve Protein Crystal Structures
score: 2.8148771, Structure, 2000, Chen, Yu Wai; Dodson, Eleanor J.; Kleywegt, Gerard J.

Conformational polymorphism of cyclosporin A
score: 2.8127482, Structure, 1994, Altschuh, Danièle et. al.

Heparin binding induces conformational changes in Adeno-associated virus serotype 2
score: 2.8121053, Journal of Structural Biology, 2009, Levy, Hazel C. et. al.

Drugging the PI3 kinome: from chemical tools to drugs in the clinic.
score: 2.8115635, Cancer research, 2010, Workman, Paul et. al.

Inside the Hsp90 inhibitors binding mode through induced fit docking
score: 2.811214, Journal of Molecular Graphics and Modelling, 2009, Lauria, Antonino; Ippolito, Mario; Almerico, Anna Maria

NMR Characterization of Monomeric and Oligomeric Conformations of Human Calcitonin and Its Interaction with EGCG
score: 2.8107594, Journal of Molecular Biology, 2012, Huang, Rui et. al.

Alternate binding mode of C-terminal phenethylamine analogs of G(t)alpha(340-350) to photoactivated rhodopsin.
score: 2.8102865, Chemical biology & drug design, 2006, Anderson, Matthew A et. al.

Crystal structure of an alkaline protease from Bacillus alcalophilus at 2.4Åresolution
score: 2.8102781, FEBS Letters, 1990, Sobek, H. et. al.

Refined Molecular Structure of Pig Pancreatic α-Amylase at 2·1 Å Resolution
score: 2.8101611, Journal of Molecular Biology, 1994, Larson, Steven B. et. al.

Dissecting the Gelsolin–Polyphosphoinositide Interaction and Engineering of a Polyphosphoinositide-sensitive Gelsolin C-terminal Half Protein
score: 2.8097571, Journal of Molecular Biology, 2002, Xian, Wujing; Janmey, Paul A

Preliminary crystallographic analysis of the bacteriophage P22 portal protein
score: 2.8096385, Journal of Structural Biology, 2002, Cingolani, Gino et. al.

Succinate:quinone oxidoreductases – what can we learn from Wolinella succinogenes quinol:fumarate reductase?
score: 2.808809, FEBS Letters, 2001, Lancaster, C.Roy D

Vertebrate membrane proteins: structure, function, and insights from biophysical approaches.
score: 2.8084981, Pharmacological reviews, 2008, Müller, Daniel J; Wu, Nan; Palczewski, Krzysztof

Enantiocomplementary enzymes: classification, molecular basis for their enantiopreference, and prospects for mirror-image biotransformations.
score: 2.8078604, Angewandte Chemie (International ed. in English), 2008, Mugford, Paul F et. al.

Structure and function of chromophores in R-Phycoerythrin at 1.9 A resolution.
score: 2.8074279, Proteins, 1999, Jiang, T; Zhang, J; Liang, D

Structural dynamics of the membrane translocation domain of colicin E9 and its interaction with TolB
score: 2.8074259, Journal of Molecular Biology, 2002, Collins, Emily S. et. al.

Stereochemistry of the chloroperoxidase active site: crystallographic and molecular-modeling studies
score: 2.8072702, Chemistry & Biology, 1998, Sundaramoorthy, M.; Terner, James; Poulos, Thomas L.

Cloning, purification and preliminary X-ray analysis of the C-terminal domain of Helicobacter pylori MotB
score: 2.8067351, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2008, Roujeinikova, Anna

Structure of dihydrodipicolinate synthase of Nicotiana sylvestris reveals novel quaternary structure 1 1 Edited by T. Richmond
score: 2.8060931, Journal of Molecular Biology, 1997, Blickling, Stefan et. al.

Of the vulnerability of orphan complex proteins: The case study of the E. coli IscU and IscS proteins
score: 2.8051396, Protein Expression and Purification, 2010, Prischi, Filippo et. al.

Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel
score: 2.8034804, Structure, 2012, Xu, Xinping et. al.

Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel
score: 2.8034804, Structure, 2012, Xu, Xinping et. al.

The Molecular Details of WPD-Loop Movement Differ in the Protein-Tyrosine Phosphatases YopH and PTP1B
score: 2.8029163, Archives of Biochemistry and Biophysics, 2012, Brandão, Tiago A.S.; Johnson, Sean J.; Hengge, Alvan C.

Structure, function, and mechanism of ribonucleotide reductases
score: 2.80249, BBA - Proteins and Proteomics, 2004, Kolberg, Matthias et. al.

The Maturational Refolding of the β-Hairpin Motif of Equine Infectious Anemia Virus Capsid Protein Extends Its Helix α1 at Capsid Assembly Locus *
score: 2.8014632, The Journal of Biological Chemistry, 2012, Chen, Kang; Piszczek, Grzegorz; Carter, Carol; Tjandra, Nico

Method for prediction of protein function from sequence using the sequence-to-structure-to-function paradigm with application to Glutaredoxins/Thioredoxins and T 1Ribonucleases 1 1 Edited by F. Cohen
score: 2.7993747, Journal of Molecular Biology, 1998, Fetrow, Jacquelyn S; Skolnick, Jeffrey

Crystal Structure of a Free Radical Enzyme, Galactose Oxidase
score: 2.7990135, Journal of Molecular Biology, 1994, Ito, Nobutoshi et. al.

Localization and orientation of heavy-atom cluster compounds in protein crystals using molecular replacement
score: 2.7969451, Acta Crystallographica Section D: Biological Crystallography, 2013, Dahms, Sven O. et. al.

Structural and biochemical characterization of the Importin-β · Ran · GTP · RanBD1 complex
score: 2.7968535, FEBS Letters, 2007, Sarić, Marc et. al.

Characterisation of the Conformational Properties of Urea-unfolded Im7: Implications for the Early Stages of Protein Folding
score: 2.7963615, Journal of Molecular Biology, 2006, Le Duff, Cécile S. et. al.

The role of structure in antibody cross-reactivity between peptides and folded proteins 1 1 Edited by J. A. Wells
score: 2.7960612, Journal of Molecular Biology, 1998, Craig, Lisa et. al.

Location of PsbY in oxygen-evolving photosystem II revealed by mutagenesis and X-ray crystallography
score: 2.7958657, FEBS Letters, 2007, Kawakami, Keisuke et. al.

Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI 1 1 Edited by P. E. Wright
score: 2.7954265, Journal of Molecular Biology, 2001, Golovanov, Alexander P. et. al.

Structure of the Human Protein Kinase MPSK1 Reveals an Atypical Activation Loop Architecture
score: 2.795081, Structure (London, England : 1993), 2008, Eswaran, Jeyanthy et. al.

Annealing in crystallography: a powerful optimization tool
score: 2.7936861, Progress in Biophysics and Molecular Biology, 1999, Brunger, Axel T.; Adams, Paul D.; Rice, Luke M.

Double electron-electron resonance shows cytochrome P450cam undergoes a conformational change in solution upon binding substrate.
score: 2.7922697, Proceedings of the National Academy of Sciences of the United States of America, 2012, Stoll, Stefan et. al.

A structural basis for the assembly and functions of a viral polymer that inactivates multiple tumor suppressors
score: 2.7912425, Cell, 2012, Ou, Horng D. et. al.

Improving Protein Crystal Quality by the Without-Oil Microbatch Method: Crystallization and Preliminary X-ray Diffraction Analysis of Glutathione Synthetase from Pseudoalteromonas haloplanktis
score: 2.7900506, International Journal of Molecular Sciences, 2011, Merlino, Antonello et. al.

The protein–lipid interface: perspectives from magnetic resonance and crystal structures
score: 2.7880723, BBA - Biomembranes, 2004, Marsh, Derek; Páli, Tibor

NMR-based insights into the conformational and interaction properties of Arkadia RING-H2 E3 Ub ligase.
score: 2.7868213, Proteins, 2012, Chasapis, Christos T et. al.

Normal mode refinement of anisotropic thermal parameters for a supramolecular complex at 3.42-A crystallographic resolution.
score: 2.7829536, Proceedings of the National Academy of Sciences of the United States of America, 2007, Poon, Billy K et. al.

Low Resolution Crystal Structure of Arenicola Erythrocruorin: Influence of Coiled Coils on the Architecture of a Megadalton Respiratory Protein
score: 2.7826179, Journal of Molecular Biology, 2007, Royer, William E.; Omartian, Michael N.; Knapp, James E.

DNA Sequence Context Conceals α-Anomeric Lesions
score: 2.7814843, Journal of Molecular Biology, 2012, Johnson, Christopher N. et. al.

Tick-derived Kunitz-type inhibitors as antihemostatic factors
score: 2.7808823, Insect Biochemistry and Molecular Biology, 2009, Corral-Rodríguez, María Ángeles et. al.

Mechanistic Insights Revealed by the Crystal Structure of a Histidine Kinase with Signal Transducer and Sensor Domains
score: 2.7802136, PLoS Biology, 2013, Wang, Chen et. al.

The crystal structure of annexin VI indicates relative rotation of the two lobes upon membrane binding
score: 2.7779362, BBA - Molecular Cell Research, 1996, Kawasaki, Hiroshi et. al.

Enhanced preference for π-bond containing substrates is correlated to Pro110 in the substrate-binding tunnel of Escherichia coli thioesterase I/protease I/lysophospholipase L 1
score: 2.777711, BBA - Proteins and Proteomics, 2007, Lee, Li-Chiun; Liaw, Yen-Chywan; Lee, Ya-Lin; Shaw, Jei-Fu

Intrinsic Domain and Loop Dynamics Commensurate with Catalytic Turnover in an Induced-Fit Enzyme
score: 2.7773385, Structure, 2009, Davulcu, Omar et. al.

Atypical Binding of the Swa2p UBA Domain to Ubiquitin
score: 2.7768188, Journal of Molecular Biology, 2009, Matta-Camacho, Edna et. al.

Solution structure of the kringle 4 domain from human plasminogen by 1H nuclear magnetic resonance spectroscopy and distance geometry
score: 2.7765543, Journal of Molecular Biology, 1990, Atkinson, R.A.; Williams, R.J.P.

Of Bits and Bugs — On the Use of Bioinformatics and a Bacterial Crystal Structure to Solve a Eukaryotic Repeat-Protein Structure
score: 2.7738578, PLoS ONE, 2010, Graebsch, Almut et. al.

Solution NMR Study of the Interaction Between NTF2 and Nucleoporin FxFG Repeats
score: 2.7731312, Journal of Molecular Biology, 2003, Morrison, Jonathan et. al.

Mechanism of Cd2+ Coordination during Slow Inactivation in Potassium Channels
score: 2.7725051, Structure, 2012, Raghuraman, H. et. al.

Crystal structure of the cyanide-inhibited Xenopus laevis Cu,Zn superoxide dismutase at 98 K
score: 2.7706558, FEBS Letters, 1994, Carugo, Kristina Djinovic et. al.

Structure of the 1–36 Amino-Terminal Fragment of Human Phospholamban by Nuclear Magnetic Resonance and Modeling of the Phospholamban Pentamer
score: 2.7706266, Biophysical Journal, 1999, Pollesello, Piero; Annila, Arto; Ovaska, Martti

Molecular basis for the action of the collagen-specific chaperone Hsp47/SERPINH1 and its structure-specific client recognition.
score: 2.7704969, Proceedings of the National Academy of Sciences of the United States of America, 2012, Widmer, Christine et. al.

Core Structure of Amyloid Fibrils Formed by Residues 106–126 of the Human Prion Protein
score: 2.7628818, Structure, 2009, Walsh, Patrick; Simonetti, Karen; Sharpe, Simon

Solution conformation and amyloid-like fibril formation of a polar peptide derived from a β-hairpin in the OspA single-layer β-sheet 1 1 Edited by P. Wright
score: 2.7614864, Journal of Molecular Biology, 2000, Ohnishi, Satoshi; Koide, Akiko; Koide, Shohei

Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy
score: 2.7613807, Nature structural & molecular biology, 2012, Ummat, Ajay et. al.

Improved molecular replacement by density- and energy-guided protein structure optimization.
score: 2.761143, Nature, 2011, DiMaio, Frank et. al.

Predicting Inactive Conformations of Protein Kinases Using Active Structures: Conformational Selection of Type-II Inhibitors
score: 2.7607846, PLoS ONE, 2011, Xu, Min; Yu, Lu; Wan, Bo; Yu, Long; Huang, Qiang

Crystal structure of yeast Cu,Zn superoxide dismutase
score: 2.7607827, Journal of Molecular Biology, 1992, Djinovic, K. et. al.

Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes.
score: 2.7604951, Proceedings of the National Academy of Sciences of the United States of America, 2012, Delfosse, Vanessa et. al.

Conformational Flexibility of α-Lactalbumin Related to its Membrane Binding Capacity
score: 2.7601406, Journal of Molecular Biology, 2005, Halskau, Øyvind et. al.

The three-dimensional structure of Escherichia coli porphobilinogen deaminase at 1.76-A resolution.
score: 2.7599253, Proteins, 1996, Louie, G V et. al.

Structure of the complex ofNeisseria gonorrhoeae N-acetyl-l-glutamate synthase with a bound bisubstrate analog
score: 2.7598955, Biochemical and Biophysical Research Communications, 2013, Zhao, Gengxiang et. al.

The 4.5 Å Structure of Human AQP2
score: 2.7594813, Journal of Molecular Biology, 2005, Schenk, Andreas D. et. al.

The Vibrio cholerae Colonization Factor GbpA Possesses a Modular Structure that Governs Binding to Different Host Surfaces
score: 2.758035, PLoS Pathogens, 2012, Wong, Edmond et. al.

The CCPN data model for NMR spectroscopy: development of a software pipeline.
score: 2.7568871, Proteins, 2005, Vranken, Wim F et. al.

Structural Characterization of the Self-Association of the Death Domain of p75 NTR
score: 2.7556261, PLoS ONE, 2013, Qu, Qianhui et. al.

Solution structure of termite-derived antimicrobial peptide, spinigerin, as determined in SDS micelle by NMR spectroscopy
score: 2.7536612, Biochemical and Biophysical Research Communications, 2003, Lee, Kwang Hwan et. al.

Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888
score: 2.7531553, Molecular Immunology, 2012, Obmolova, Galina et. al.

The generation of a 1-hydroxy-2-naphthoate 1,2-dioxygenase by single point mutations of salicylate 1,2-dioxygenase – Rational design of mutants and the crystal structures of the A85H and W104Y variants
score: 2.7498061, Journal of Structural Biology, 2012, Ferraroni, Marta et. al.

The generation of a 1-hydroxy-2-naphthoate 1,2-dioxygenase by single point mutations of salicylate 1,2-dioxygenase – Rational design of mutants and the crystal structures of the A85H and W104Y variants
score: 2.7498061, Journal of Structural Biology, 2012, Ferraroni, Marta et. al.

Solution structure of FK506 bound to FKBP-12
score: 2.7496484, FEBS Letters, 1992, Lepre, Christopher A.; Thomson, John A.; Moore, Jonathan M.

Turned on for degradation: ATPase-independent degradation by ClpP
score: 2.7495865, Journal of Structural Biology, 2009, Bewley, Maria C. et. al.

Oxidation State-dependent Protein-Protein Interactions in Disulfide Cascades
score: 2.7487922, The Journal of Biological Chemistry, 2011, Mavridou, Despoina A. I. et. al.

Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T.
score: 2.7483737, Proceedings of the National Academy of Sciences of the United States of America, 2010, Tachiwana, Hiroaki et. al.

Comparison of Solution and Crystal Structures of PreQ 1 Riboswitch Reveals Calcium-Induced Changes in Conformation and Dynamics
score: 2.7455901, Journal of the American Chemical Society, 2011, Zhang, Qi; Kang, Mijeong; Peterson, Robert D.; Feigon, Juli

A pH-dependent conformational change, rather than the chemical step, appears to be rate-limiting in the hammerhead ribozyme cleavage reaction 1 1 Edited by J. Doudna
score: 2.7444965, Journal of Molecular Biology, 2002, Murray, James B.; Dunham, Christine M.; Scott, William G.

Prokaryotic DNA polymerase I: evolution, structure, and “base flipping” mechanism for nucleotide selection 1 1 Edited by J. H. Miller
score: 2.7433176, Journal of Molecular Biology, 2001, Patel, Premal H. et. al.

Structural predictions of AgfA, the insoluble fimbrial subunit of Salmonella thin aggregative fimbriae 1 1 Edited by W. Baumeister
score: 2.7420962, Journal of Molecular Biology, 1999, Collinson, S.K; Parker, J.M.R; Hodges, R.S; Kay, W.W

Crystal structures of wild-type and mutated cyclophilin B that causes hyperelastosis cutis in the American quarter horse
score: 2.7415496, BMC Research Notes, 2012, Boudko, Sergei P et. al.

Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli.
score: 2.7407987, Proceedings of the National Academy of Sciences of the United States of America, 2004, Ma, Che; Chang, Geoffrey

A structural perspective on MHC class I recognition by killer cell immunoglobulin-like receptors
score: 2.7395523, Molecular Immunology, 2002, Boyington, Jeffrey C; Sun, Peter D

Biophysical methods
score: 2.7386053, Current Opinion in Structural Biology, 1995,

A Phage Tubulin Assembles Dynamic Filaments by an Atypical Mechanism to Center Viral DNA within the Host Cell
score: 2.738493, Cell, 2012, Kraemer, James A. et. al.

Conservation of Functionally Important Global Motions in an Enzyme Superfamily across Varying Quaternary Structures
score: 2.7381086, Journal of Molecular Biology, 2012, Luebbering, Emily K. et. al.

Structural Tolerance versus Functional Intolerance to Mutation of Hydrophobic Core Residues Surrounding Cavities in a Parvovirus Capsid
score: 2.7379609, Journal of Molecular Biology, 2006, Carreira, Aura; Mateu, Mauricio G.

AKT crystal structure and AKT-specific inhibitors.
score: 2.73754, Oncogene, 2005, Kumar, Chandra C; Madison, Vincent

Effects of environment on the structure of Pyrococcus furiosus rubredoxin: a molecular dynamics study.
score: 2.737492, Proteins, 2005, Ergenekan, Can E; Tan, Ming-Liang; Ichiye, Toshiko

An RTX Transporter Tethers Its Unfolded Substrate during Secretion via a Unique N-Terminal Domain
score: 2.7346443, Structure, 2012, Lecher, Justin et. al.

An RTX Transporter Tethers Its Unfolded Substrate during Secretion via a Unique N-Terminal Domain
score: 2.7346443, Structure, 2012, Lecher, Justin et. al.

Binding mode of novel 1-substituted quinazoline derivatives to poly(ADP-ribose) polymerase-catalytic domain, revealed by X-ray crystal structure analysis of complexes
score: 2.7346345, BBA - Proteins and Proteomics, 2006, Matsumoto, Keita et. al.

Topological Determinants of Protein Domain Swapping
score: 2.7345461, Structure, 2006, Ding, Feng et. al.

Nonoxidizable ubiquinol derivatives that are suitable for the study of the ubiquinol oxidation site in the cytochrome bc 1 complex
score: 2.7340929, BBA - Bioenergetics, 2002, Zhang, Li et. al.

Benzimidazole inhibitors of the protein kinase CHK2: Clarification of the binding mode by flexible side chain docking and protein–ligand crystallography
score: 2.7340631, Bioorganic & Medicinal Chemistry, 2012, Matijssen, Cornelis et. al.

Benzimidazole inhibitors of the protein kinase CHK2: Clarification of the binding mode by flexible side chain docking and protein–ligand crystallography
score: 2.7340631, Bioorganic & Medicinal Chemistry, 2012, Matijssen, Cornelis et. al.

Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis.
score: 2.7334299, Proceedings of the National Academy of Sciences of the United States of America, 2010, Maslennikov, Innokentiy et. al.

A Cyclic Peptide Inhibitor of ApoC-II Peptide Fibril Formation: Mechanistic Insight from NMR and Molecular Dynamics Analysis
score: 2.7333146, Journal of Molecular Biology, 2012, Griffin, Michael D.W. et. al.

CoNSEnsX: an ensemble view of protein structures and NMR-derived experimental data
score: 2.7332618, BMC Structural Biology, 2010, Ángyán, Annamária F et. al.

Carbohydrate recognition mechanism of HA70 from Clostridium botulinum deduced from X-ray structures in complexes with sialylated oligosaccharides
score: 2.7332199, FEBS Letters, 2012, Yamashita, Satoshi et. al.

Structure-based Discovery of a Pore-binding Ligand: Towards Assembly Inhibitors for Cholera and Related AB 5Toxins
score: 2.7324052, Journal of Molecular Biology, 1999, Hovey, Bianca T. et. al.

Overexpression, purification, crystallization and data collection of Sulfolobus solfataricus Sso6206, a novel highly conserved protein
score: 2.7309666, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2006, McEwan, Andrew R. et. al.

Investigation of Overhauser effects between pseudouridine and water protons in RNA helices.
score: 2.7301301, Proceedings of the National Academy of Sciences of the United States of America, 2002, Newby, Meredith I; Greenbaum, Nancy L

From biomolecular structure to functional understanding: new NMR developments narrow the gap
score: 2.728627, Current Opinion in Structural Biology, 2009, Grzesiek, Stephan; Sass, Hans-Jürgen

Ligand-Induced Strain in Hydrogen Bonds of the c-Src SH3 Domain Detected by NMR
score: 2.7271368, Journal of Molecular Biology, 2000, Cordier, Florence et. al.

Knowledge-Based Real-Space Explorations for Low-Resolution Structure Determination
score: 2.727035, Structure, 2006, Furnham, Nicholas et. al.

High-resolution polypeptide structure in a lamellar phase lipid environment from solid state NMR derived orientational constraints
score: 2.7239408, Structure, 1997, Ketchem, RR; Roux, B; Cross, TA

Crystal structure of RVV-X: An example of evolutionary gain of specificity by ADAM proteinases
score: 2.7236798, FEBS Letters, 2007, Takeda, Soichi; Igarashi, Tomoko; Mori, Hidezo

AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome
score: 2.7230846, Nucleic Acids Research, 2012, Gaetani, Massimiliano et. al.

A structural difference limited to one residue of the antigenic peptide can profoundly alter the biological outcome of the TCR-peptide/MHC class I interaction.
score: 2.722964, Journal of immunology (Baltimore, Md. : 1950), 2001, Thomson, C T et. al.

An all-atom model of the pore-like structure of hexameric VP40 from Ebola: Structural insights into the monomer–hexamer transition
score: 2.7225459, Journal of Structural Biology, 2005, Nguyen, Tam Luong et. al.

Super-resolution biomolecular crystallography with low-resolution data
score: 2.7222836, Nature, 2010, Schröder, Gunnar F.; Levitt, Michael; Brunger, Axel T.

Crystallographic studies of DNA helix structure
score: 2.7213213, Biophysical Chemistry, 1994, Heinemann, Udo; Alings, Claudia; Hahn, Michael

Biochemical properties and catalytic domain structure of the CcmH protein from Escherichia coli
score: 2.7207345, BBA - Proteins and Proteomics, 2012, Zheng, Xue-Ming et. al.

Biochemical properties and catalytic domain structure of the CcmH protein from Escherichia coli
score: 2.7207345, BBA - Proteins and Proteomics, 2012, Zheng, Xue-Ming et. al.

Solution NMR Structure of Putidaredoxin–Cytochrome P450cam Complex via a Combined Residual Dipolar Coupling–Spin Labeling Approach Suggests a Role for Trp106 of Putidaredoxin in Complex Formation
score: 2.719012, Journal of Molecular Biology, 2008, Zhang, Wei et. al.

Cross-validated maximum likelihood enhances crystallographic simulated annealing refinement.
score: 2.7188069, Proceedings of the National Academy of Sciences of the United States of America, 1997, Adams, P D; Pannu, N S; Read, R J; Brünger, A T

Protein tyrosine kinase–substrate interactions
score: 2.7181309, Current Opinion in Structural Biology, 2006, Bose, Ron; Holbert, Marc A; Pickin, Kerry A; Cole, Philip A

An X-ray diffraction and X-ray absorption spectroscopy joint study of neuroglobin
score: 2.7176368, Archives of Biochemistry and Biophysics, 2008, Arcovito, Alessandro et. al.

A similar pattern of interaction for different antibodies with a major antigenic site of foot-and-mouth disease virus: implications for intratypic antigenic variation.
score: 2.7163967, Journal of virology, 1998, Verdaguer, N et. al.

Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed β-propeller domain of the HIV-1 cellular interactor EED
score: 2.7159029, Virology Journal, 2008, Rakotobe, Dina et. al.

Understanding the structure and function of catalases: clues from molecular evolution and in vitro mutagenesis
score: 2.7148094, Progress in Biophysics and Molecular Biology, 1999, Zámocký, Marcel; Koller, Franz

Low resolution structure of interleukin-1β in solution derived from 1H 15N heteronuclear three-dimensional nuclear magnetic resonance spectroscopy
score: 2.7141498, Journal of Molecular Biology, 1990, Clore, G.Marius et. al.

NMR characterization of a 264-residue hyperthermostable endo-β-1,3-glucanase
score: 2.7139379, Biochemical and Biophysical Research Communications, 2010, Ippel, Johannes H. et. al.

Photoreversible inhibition of cholinesterases: catalytic serine-labeled caged butyrylcholinesterase.
score: 2.7136497, Chembiochem : a European journal of chemical biology, 2003, Loudwig, Sandra et. al.

Complementary Structural Mass Spectrometry Techniques Reveal Local Dynamics in Functionally Important Regions of a Metastable Serpin
score: 2.7123819, Structure, 2008, Zheng, Xiaojing; Wintrode, Patrick L.; Chance, Mark R.

Two Different Conformational States of the KirBac3.1 Potassium Channel Revealed by Electron Crystallography
score: 2.7108585, Structure, 2005, Kuo, Anling et. al.

Probabilistic Interaction Network of Evidence Algorithm and its Application to Complete Labeling of Peak Lists from Protein NMR Spectroscopy
score: 2.7099021, PLoS Computational Biology, 2009, Bahrami, Arash et. al.

Lack of involvement of strand s1′A of the viral serpin CrmA in anti-apoptotic or caspase-inhibitory functions
score: 2.7096787, Archives of Biochemistry and Biophysics, 2005, Simonovic, Miljan et. al.

Crystallization and preliminary crystallographic analysis of the signal recognition particle SRPΦ14-9 fusion protein
score: 2.7088264, FEBS Letters, 1996, Birse, Darcy E.A. et. al.

Thiol-based angiotensin-converting enzyme 2 inhibitors: P 1 modifications for the exploration of the S 1 subsite
score: 2.7084233, Bioorganic & Medicinal Chemistry Letters, 2008, Deaton, David N. et. al.

Experimental Evolution of Adenylate Kinase Reveals Contrasting Strategies toward Protein Thermostability
score: 2.707379, Biophysical Journal, 2010, Miller, Corwin et. al.

Lipids in photosynthetic reaction centres: Structural roles and functional holes
score: 2.7062326, Progress in Lipid Research, 2007, Jones, Michael R.

Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
score: 2.7051028, The EMBO Journal, 2013, Sauguet, Ludovic et. al.

Structural studies of large nucleoprotein particles, vaults
score: 2.703218, Proceedings of the Japan Academy. Series B, Physical and Biological Sciences, 2012, TANAKA, Hideaki; TSUKIHARA, Tomitake

Structure-based Combinatorial Protein Engineering (SCOPE)
score: 2.7029774, Journal of Molecular Biology, 2002, O'Maille, Paul E.; Bakhtina, Marina; Tsai, Ming-Daw

Structure and Function of the Transcription Elongation Factor GreB Bound to Bacterial RNA Polymerase
score: 2.6996147, Cell, 2003, Opalka, Natacha et. al.

Refined Crystal Structure of Human Transforming Growth Factor β2 at 1·5 Å Resolution
score: 2.6982492, Journal of Molecular Biology, 1993, Schlunegger, M.P.; Grütter, M.G.

CS23D: a web server for rapid protein structure generation using NMR chemical shifts and sequence data
score: 2.6981931, Nucleic Acids Research, 2008, Wishart, David S. et. al.

Structural study of Ac-Phe-[Orn-Pro-dCha-Trp-Arg], a potent C5a receptor antagonist, by NMR.
score: 2.6981725, Biopolymers, 2008, Zhang, Li; Mallik, Buddhadeb; Morikis, Dimitrios

NCS-constrained exhaustive search using oligomeric models
score: 2.6973241, Acta Crystallographica Section D: Biological Crystallography, 2007, Isupov, Michail N.; Lebedev, Andrey A.

Glycyrrhizin Binds to High-Mobility Group Box 1 Protein and Inhibits Its Cytokine Activities
score: 2.6967655, Chemistry & Biology, 2007, Mollica, Luca et. al.

Crystallographic detection of a second ligand binding site in influenza virus hemagglutinin.
score: 2.6959039, Proceedings of the National Academy of Sciences of the United States of America, 1992, Sauter, N K et. al.

Crystal Structure of the Yeast Vacuolar ATPase Heterotrimeric EGChead Peripheral Stalk Complex
score: 2.6953564, Structure, 2012, Oot, Rebecca A. et. al.

Crystal Structure of the Yeast Vacuolar ATPase Heterotrimeric EGChead Peripheral Stalk Complex
score: 2.6953564, Structure, 2012, Oot, Rebecca A. et. al.

The design, synthesis, and biological evaluation of PIM kinase inhibitors
score: 2.6950741, Bioorganic & Medicinal Chemistry Letters, 2012, Tsuhako, Amy Lew et. al.

The design, synthesis, and biological evaluation of PIM kinase inhibitors
score: 2.6950741, Bioorganic & Medicinal Chemistry Letters, 2012, Tsuhako, Amy Lew et. al.

The design, synthesis and biological evaluation of PIM kinase inhibitors
score: 2.6950741, Bioorganic & Medicinal Chemistry Letters, 2012, Tsuhako, Amy Lew et. al.

COCO: a simple tool to enrich the representation of conformational variability in NMR structures.
score: 2.6936635, Proteins, 2009, Laughton, Charles A; Orozco, Modesto; Vranken, Wim

The C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rate
score: 2.6935509, Nature Communications, 2012, Irie, Katsumasa; Shimomura, Takushi; Fujiyoshi, Yoshinori

Crystallization and crystallographic investigations of the small subunit of mouse ribonucleotide reductase
score: 2.6931381, FEBS Letters, 1995, Nielsen, Bettina Bryde et. al.

3 Peptide Deformylase Inhibitors
score: 2.6924775, Progress in Medicinal Chemistry, 2006, Aubart, Kelly; Zalacain, Magdalena

The structure of coxsackievirus B3 at 3.5 å resolution
score: 2.6921213, Structure, 1995, Muckelbauer, Jodi K et. al.

Fragment-based screening using X-ray crystallography and NMR spectroscopy
score: 2.6915836, Current Opinion in Chemical Biology, 2007, Jhoti, Harren et. al.

The modular structure of haemagglutinin/adhesin regions in gingipains of Porphyromonas gingivalis.
score: 2.6895918, Molecular microbiology, 2011, Li, Nan et. al.

Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2
score: 2.6894689, Structure, 2013, Dalhus, Bjørn et. al.

Resonance assignment and secondary structure of the middle MA-3 domain and complete tandem MA-3 region of the tumour suppressor protein Pdcd4
score: 2.6893974, Biomolecular Nmr Assignments, 2009, Waters, Lorna C. et. al.

Metallo-aminopeptidase inhibitors
score: 2.688989, Biochimie, 2010, Mucha, Artur; Drag, Marcin; Dalton, John P.; Kafarski, Paweł

The high-resolution structure of the triplex formed by the GAA/TTC triplet repeat associated with Friedreich’s ataxia 1 1 Edited by I. Tinoco
score: 2.6881409, Journal of Molecular Biology, 1999, Mariappan, S.V.Santhana et. al.

Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum
score: 2.6868959, Biochemical Pharmacology, 2013, Eichhorn, Tolga et. al.

Structure-based Mechanism of ADP-ribosylation by Sirtuins *
score: 2.6859251, The Journal of Biological Chemistry, 2009, Hawse, William F.; Wolberger, Cynthia

Disulfide Biochemistry in 2-Cys Peroxiredoxin: Requirement of Glu50 and Arg146 for the Reduction of Yeast Tsa1 by Thioredoxin
score: 2.6857911, Journal of Molecular Biology, 2012, Tairum, Carlos A. et. al.

Disulfide Biochemistry in 2-Cys Peroxiredoxin: Requirement of Glu50 and Arg146 for the Reduction of Yeast Tsa1 by Thioredoxin
score: 2.6857911, Journal of Molecular Biology, 2012, Tairum, Carlos A. et. al.

Disulfide Biochemistry in 2-Cys Peroxiredoxin: Requirement of Glu50 and Arg146 for the Reduction of Yeast Tsa1 by Thioredoxin
score: 2.6857911, Journal of Molecular Biology, 2012, Tairum, Carlos A. et. al.

Mapping of the Auto-inhibitory Interactions of Protein Kinase R by Nuclear Magnetic Resonance
score: 2.6853007, Journal of Molecular Biology, 2006, Gelev, Vladimir et. al.

Cooperative metal binding and helical folding in model peptides of treble-clef zinc fingers.
score: 2.6840486, Chemistry (Weinheim an der Bergstrasse, Germany), 2009, Sénèque, Olivier et. al.

Firefly Luciferase in Chemical Biology: A Compendium of Inhibitors, Mechanistic Evaluation of Chemotypes, and Suggested Use As a Reporter
score: 2.6838232, Chemistry & Biology, 2012, Thorne, Natasha et. al.

Dissecting the stability of a β-hairpin peptide that folds in water: NMR and molecular dynamics analysis of the β-turn and β-strand contributions to folding 1 1 Edited by P. E. Wright
score: 2.6830603, Journal of Molecular Biology, 1999, Griffiths-Jones, Samuel R et. al.

Identification of pyrimidine derivatives as hSMG-1 inhibitors
score: 2.6806878, Bioorganic & Medicinal Chemistry Letters, 2012, Gopalsamy, Ariamala et. al.

Identification of pyrimidine derivatives as hSMG-1 inhibitors
score: 2.6806878, Bioorganic & Medicinal Chemistry Letters, 2012, Gopalsamy, Ariamala et. al.

Structure of the inhibitor complex of old yellow enzyme from Trypanosoma cruzi
score: 2.6790364, Journal of Synchrotron Radiation, 2010, Yamaguchi, Keishi et. al.

Hydrophobic benzoic acids as inhibitors of influenza neuraminidase
score: 2.6781196, Bioorganic & Medicinal Chemistry, 1999, Atigadda, Venkatram R. et. al.

Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit.
score: 2.6778235, Proceedings of the National Academy of Sciences of the United States of America, 2012, Boura, Evzen; Hurley, James H

Calicheamicin-DNA complexes: warhead alignment and saccharide recognition of the minor groove.
score: 2.6774241, Proceedings of the National Academy of Sciences of the United States of America, 1995, Ikemoto, N et. al.

Model for the Peptide-Free Conformation of Class II MHC Proteins
score: 2.6765561, PLoS ONE, 2008, Painter, Corrie A. et. al.

Resisting degradation by human elastase: Commonality of design features shared by ‘canonical’ plant and bacterial macrocyclic protease inhibitor scaffolds
score: 2.6758107, Bioorganic & Medicinal Chemistry, 2007, Brauer, Arnd B.E. et. al.

Nectin ectodomain structures reveal a canonical adhesive interface
score: 2.6749912, Nature structural & molecular biology, 2012, Harrison, Oliver J. et. al.

Structural insights into the PIP 2 recognition by syntenin-1 PDZ domain
score: 2.6749044, Biochemical and Biophysical Research Communications, 2008, Sugi, Takuma et. al.

3 Peptide Deformylase Inhibitors
score: 2.674755, Progress in Medicinal Chemistry, 2006, Aubart, Kelly; Zalacain, Magdalena

Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation
score: 2.6738873, Nucleic Acids Research, 2012, Hashimoto, Hideharu; Zhang, Xing; Cheng, Xiaodong

An integrated approach to structural genomics
score: 2.673562, Progress in Biophysics and Molecular Biology, 2000, Heinemann, Udo et. al.

Structure of Stable Protein Folding Intermediates by Equilibrium ϕ-Analysis: The Apoflavodoxin Thermal Intermediate
score: 2.6732564, Journal of Molecular Biology, 2004, Campos, Luis A. et. al.

Structural and Functional Studies of the Response Regulator HupR
score: 2.6731325, Journal of Molecular Biology, 2006, Davies, Karen M. et. al.

Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å.
score: 2.6729609, Nature, 2012, Johnson, Zachary Lee; Cheong, Cheom-Gil; Lee, Seok-Yong

A redox-dependent interaction between two electron-transfer partners involved in photosynthesis.
score: 2.6728096, EMBO reports, 2000, Morales, R et. al.

Crystal and molecular structure of RNase Rh, a new class of microbial ribonuclease from Rhizopus niveus
score: 2.6721569, FEBS Letters, 1992, Kurihara, Hiroyuki et. al.

Escherichia coli RNA polymerase core and holoenzyme structures.
score: 2.6720493, The EMBO journal, 2000, Finn, R D; Orlova, E V; Gowen, B; Buck, M; van Heel, M

Location of the dsRNA-Dependent Polymerase, VP1, in Rotavirus Particles
score: 2.672042, Journal of Molecular Biology, 2013, Estrozi, Leandro F. et. al.

Both lipid environment and pH are critical for determining physiological solution structure of 3-D-conserved epitopes of the HIV-1 gp41-MPER peptide P1.
score: 2.6718971, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Coutant, Jérôme et. al.

Structure and assembly of P-pili: a protruding hinge region used for assembly of a bacterial adhesion filament.
score: 2.6701369, Proceedings of the National Academy of Sciences of the United States of America, 2006, Mu, Xiang-Qi; Bullitt, Esther

A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion.
score: 2.6686658, The EMBO journal, 2011, Kurze, Alexander et. al.

Preparation and X-ray crystallographic analysis of rubredoxin crystals from Desulfovibrio gigas to beyond ultra-high 0.68 Å resolution
score: 2.6679503, Biochemical and Biophysical Research Communications, 2003, Chen, Chun-Jung; Liu, Ming-Yih; Chen, Yi-Ting; LeGall, Jean

Structural dynamics of the ribosome
score: 2.6678744, Current Opinion in Chemical Biology, 2008, Korostelev, Andrei; Ermolenko, Dmitri N; Noller, Harry F

Structural and Functional Analysis of the Pore-Forming Toxin NetB from Clostridium perfringens
score: 2.6678322, mBio, 2013, Yan, Xu-Xia et. al.

Chemical shift assignment and structural plasticity of a HIV fusion peptide derivative in dodecylphosphocholine micelles
score: 2.6672572, BBA - Biomembranes, 2007, Gabrys, Charles M.; Weliky, David P.

The structure of the lipid-embedded potassium channel voltage sensor determined by double-electron-electron resonance spectroscopy.
score: 2.6668117, Protein science : a publication of the Protein Society, 2008, Vamvouka, Magdalini et. al.

Structural Insights into the Assembly of CARMA1 and BCL10
score: 2.6654407, PLoS ONE, 2012, Li, Siwei; Yang, Xue; Shao, Juan; Shen, Yuequan

Structural basis for the binding of proline-rich peptides to SH3 domains
score: 2.6641564, Cell, 1994, Yu, Hongtao et. al.

NMR studies of the pbx1 TALE homeodomain protein free in solution and bound to DNA: proposal for a mechanism of HoxB1-pbx1-DNA complex assembly 1 1 Edited by P. E. Wright
score: 2.6634495, Journal of Molecular Biology, 1999, Jabet, Carole et. al.

Context-Dependent Remodeling of Structure in Two Large Protein Fragments
score: 2.6631762, Journal of Molecular Biology, 2010, Schellenberg, Matthew J. et. al.

Miniaturized proteins: the backbone cyclic proteinomimetic approach 1 1 Edited by A. R. Fersht
score: 2.6618715, Journal of Molecular Biology, 1999, Kasher, Ron; Oren, Deena A; Barda, Yaniv; Gilon, Chaim

In Situ Proteolysis to Generate Crystals for Structure Determination: An Update
score: 2.6617151, PLoS ONE, 2009, Wernimont, Amy; Edwards, Aled

Structural and Binding Study of Modified siRNAs with the Agonaute 2 PAZ Domain by NMR Spectroscopy.
score: 2.661234, Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Maiti, Mohitosh et. al.

Binding of N -Acetylglucosamine (GlcNAc) β1–6-branched Oligosaccharide Acceptors to β4-Galactosyltransferase I Reveals a New Ligand Binding Mode *
score: 2.661185, The Journal of Biological Chemistry, 2012, Ramakrishnan, Boopathy et. al.

X-ray crystal structure of the fluoride derivative of Aplysia limacina ferric myoglobin at 2·0 Å resolution
score: 2.6590668, Journal of Molecular Biology, 1990, Bolognesi, Martino et. al.

Effects of side-chain characteristics on stability and oligomerization state of a de Novo-designed model coiled-coil: 20 amino acid substitutions in position “d” 1 1 Edited by P. E. Wright
score: 2.6570921, Journal of Molecular Biology, 2000, Tripet, Brian et. al.

Analysis of Structure–Function Relationships in the Colibactin-Maturating Enzyme ClbP
score: 2.6565127, Journal of Molecular Biology, 2012, Cougnoux, Antony et. al.

Analysis of Structure–Function Relationships in the Colibactin-Maturating Enzyme ClbP
score: 2.6565127, Journal of Molecular Biology, 2012, Cougnoux, Antony et. al.

A stomatin dimer modulates the activity of acid-sensing ion channels
score: 2.6504124, The EMBO Journal, 2012, Brand, Janko et. al.

The Difficult Case of Crystallization and Structure Solution for the ParC55 Breakage-Reunion Domain of Topoisomerase IV from Streptococcus pneumoniae
score: 2.6496173, PLoS ONE, 2008, Sohi, Maninder K. et. al.

Crystal structure of cyanobacterial photosystem II at 3.0 Å resolution: A closer look at the antenna system and the small membrane-intrinsic subunits
score: 2.6495054, Plant Physiology and Biochemistry, 2008, Müh, Frank; Renger, Thomas; Zouni, Athina

Molecular Mechanisms Modulating Glutamate Kinase Activity. Identification of the Proline Feedback Inhibitor Binding Site
score: 2.6490519, Journal of Molecular Biology, 2010, Pérez-Arellano, Isabel et. al.

New applications of simulated annealing in X-ray crystallography and solution NMR
score: 2.6489584, Structure, 1997, Brünger, Axel T; Adams, Paul D; Rice, Luke M

New insights into the chemistry of fac-[Ru(CO)3]2+ fragments in biologically relevant conditions: The CO releasing activity of [Ru(CO)3Cl2(1,3-thiazole)], and the X-ray crystal structure of its adduct with lysozyme
score: 2.6486298, Journal of Inorganic Biochemistry, 2012, Santos, M.F.A. et. al.

New insights into the chemistry of fac-[Ru(CO)3]2+ fragments in biologically relevant conditions: The CO releasing activity of [Ru(CO)3Cl2(1,3-thiazole)], and the X-ray crystal structure of its adduct with lysozyme
score: 2.6486298, Journal of Inorganic Biochemistry, 2012, Santos, M.F.A. et. al.

Annexin A5 D226K structure and dynamics: identification of a molecular switch for the large-scale conformational change of domain III
score: 2.6481039, FEBS Letters, 2001, Sopkova-De Oliveira Santos, Jana et. al.

Conservation of Functionally Important Global Motions in an Enzyme Superfamily across Varying Quaternary Structures
score: 2.6462284, Journal of Molecular Biology, 2012, Luebbering, Emily K. et. al.

Structural studies of the mechanism for biosensing antibiotics in a fluorescein-labeled β -lactamase
score: 2.6456391, BMC Structural Biology, 2011, Wong, Wai-Ting et. al.

Molecular Architecture of the Undecameric Rotor of a Bacterial Na +-ATP Synthase
score: 2.6453664, Journal of Molecular Biology, 2002, Vonck, Janet et. al.

The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4–NOT deadenylase complex
score: 2.6449057, Nucleic Acids Research, 2012, Petit, Alain-Pierre et. al.

Disordered to ordered folding in the regulation of diphtheria toxin repressor activity.
score: 2.6439548, Proceedings of the National Academy of Sciences of the United States of America, 2001, Twigg, P D et. al.

Architecture of the Herpes Simplex Virus Major Capsid Protein Derived from Structural Bioinformatics
score: 2.6437091, Journal of Molecular Biology, 2003, Baker, Matthew L. et. al.

Identification of a Defined Epitope on the Surface of the Active RecA-DNA Filament Using a Monoclonal Antibody and Three-dimensional Reconstruction 1 1 Edited by W. Baumeister
score: 2.6425907, Journal of Molecular Biology, 1998, Yu, Xiong; Shibata, Takehiko; Egelman, Edward H

The natural product capsaicin inhibits photosynthetic electron transport at the reducing side of photosystem II and purple bacterial reaction center: structural details of capsaicin binding
score: 2.6421826, BBA - Bioenergetics, 2000, Spyridaki, A. et. al.

Crystallization and structural analysis of bullfrog red cell L-subunit ferritins.
score: 2.6413944, Proteins, 1994, Trikha, J et. al.

Open Interface and Large Quaternary Structure Movements in 3D Domain Swapped Proteins: Insights from Molecular Dynamics Simulations of the C-Terminal Swapped Dimer of Ribonuclease A
score: 2.6401377, Biophysical Journal, 2005, Merlino, Antonello et. al.

Quantitative NMR Studies of High Molecular Weight Proteins: Application to Domain Orientation and Ligand Binding in the 723 Residue Enzyme Malate Synthase G
score: 2.6396597, Journal of Molecular Biology, 2003, Tugarinov, Vitali; Kay, Lewis E.

Structures of DNA and RNA polymerases and their interactions with nucleic acid substrates
score: 2.6396106, Current Opinion in Structural Biology, 1995, Arnold, Edward et. al.

Sequence and Structure Classification of Kinases
score: 2.6391435, Journal of Molecular Biology, 2002, Cheek, Sara; Zhang, Hong; Grishin, Nick V

Zinc Potentiates GluK3 Glutamate Receptor Function by Stabilizing the Ligand Binding Domain Dimer Interface
score: 2.6380024, Neuron, 2012, Veran, Julien et. al.

Molecular mechanisms of ligand-mediated attenuation of DNA binding by MarR family transcriptional regulators.
score: 2.6379924, Journal of molecular cell biology, 2010, Perera, Inoka C; Grove, Anne

Detailed structural and assembly model of the type II secretion pilus from sparse data.
score: 2.6375138, Proceedings of the National Academy of Sciences of the United States of America, 2010, Campos, Manuel et. al.

Nuclear magnetic resonance solution structure of the α-neurotoxin from the black mamba ( Dendroaspis polylepis polylepis)
score: 2.6369054, Journal of Molecular Biology, 1992, Brown, Larry R.; Wüthrich, Kurt

Structure-Based Design of a Photocontrolled DNA Binding Protein
score: 2.6353298, Journal of Molecular Biology, 2010, Morgan, Stacy-Anne et. al.

Imaging RNA and dynamic protein segments with low-resolution virus crystallography: experimental design, data processing and implications of electron density maps 1 1 Edited by D. Rees
score: 2.6348916, Journal of Molecular Biology, 1998, Tsuruta, H; Reddy, V.S; Wikoff, W.R; Johnson, J.E

Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathway.
score: 2.634569, Journal of pineal research, 2012, Botros, Hany Goubran et. al.

A-tract bending: insights into experimental structures by computational models 1 1 Edited by Dr I. Tinoco
score: 2.634482, Journal of Molecular Biology, 2000, Strahs, Daniel; Schlick, Tamar

Analysis of hapten binding and catalytic determinants in a family of catalytic antibodies 1 1 Edited by I. A. Wilson
score: 2.6343555, Journal of Molecular Biology, 1998, Ulrich, Helle D; Schultz, Peter G

Structure and function of the radical enzyme ribonucleotide reductase
score: 2.6342887, Progress in Biophysics and Molecular Biology, 2001, Eklund, Hans et. al.

Probing the pH-dependent structural features of alpha-KTx12.1, a potassium channel blocker from the scorpion Tityus serrulatus.
score: 2.6339002, Protein science : a publication of the Protein Society, 2005, Oyama, Sérgio et. al.

Structure-Activity Relationships and Key Structural Feature of Pyridyloxybenzene-Acylsulfonamides as New, Potent, and Selective Peroxisome Proliferator-Activated Receptor (PPAR) γ Agonists
score: 2.6329027, Bioorganic & Medicinal Chemistry, 2012, Rikimaru, Kentaro et. al.

Structural Determinants for Activity and Specificity of the Bacterial Toxin LlpA
score: 2.6327027, PLoS Pathogens, 2013, Ghequire, Maarten G. K. et. al.

Molecular mimicry of substrate oxygen atoms by water molecules in the beta-amylase active site.
score: 2.6321347, Protein science : a publication of the Protein Society, 2001, Pujadas, G; Palau, J

Targeting protein-protein interactions: lessons from p53/MDM2.
score: 2.6319889, Biopolymers, 2007, Murray, Justin K; Gellman, Samuel H

Carbohydrate recognition mechanism of HA70 from Clostridium botulinum deduced from X-ray structures in complexes with sialylated oligosaccharides
score: 2.6309828, FEBS Letters, 2012, Yamashita, Satoshi et. al.

Applying an Empirical Hydropathic Forcefield in Refinement May Improve Low-Resolution Protein X-Ray Crystal Structures
score: 2.6289595, PLoS ONE, 2011, Koparde, Vishal N.; Scarsdale, J. Neel; Kellogg, Glen E.

Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
score: 2.628612, Proceedings of the National Academy of Sciences of the United States of America, 2011, Akutsu, Masato et. al.

Determination of the secondary structure and global topology of the 44 kda ectodomain of gp41 of the simian immunodeficiency virus by multidimensional nuclear magnetic resonance spectroscopy 1 1 Edited by P. E. Wright
score: 2.6285042, Journal of Molecular Biology, 1997, Caffrey, Michael et. al.

Solution mapping of T cell receptor docking footprints on peptide-MHC.
score: 2.6277585, Proceedings of the National Academy of Sciences of the United States of America, 2007, Varani, Luca et. al.

Biological function made crystal clear — annotation of hypothetical proteins via structural genomics
score: 2.6273872, Current Opinion in Biotechnology, 2000, Eisenstein, Edward et. al.

Structural insights into the catalytic mechanism of sphingomyelinases D and evolutionary relationship to glycerophosphodiester phosphodiesterases
score: 2.6258374, Biochemical and Biophysical Research Communications, 2006, Murakami, Mário T. et. al.

Effects of Heme on the Structure of the Denatured State and Folding Kinetics of Cytochrome b 562
score: 2.6248371, Journal of Molecular Biology, 2005, Garcia, Pascal et. al.

Molten globule structure of equine β-lactoglobulin probed by hydrogen exchange 1 1 Edited by P. E. Wright
score: 2.6245863, Journal of Molecular Biology, 2000, Kobayashi, Takuji; Ikeguchi, Masamichi; Sugai, Shintaro

Structure and mechanism of Escherichia coli RecA ATPase.
score: 2.6243301, Molecular microbiology, 2005, Bell, Charles E

Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa
score: 2.6228612, Bioorganic & Medicinal Chemistry, 2007, Kochanny, Monica J. et. al.

DNA-induced conformational changes are the basis for cooperative dimerization by the DNA binding domain of the retinoid X receptor 1 1 Edited by F. E. Cohen
score: 2.6217792, Journal of Molecular Biology, 1998, Holmbeck, Signe M.A.; Dyson, H.Jane; Wright, Peter E.

Crystal structure and functional analysis of JMJD5 indicate an alternate specificity and function.
score: 2.6215798, Molecular and cellular biology, 2012, Del Rizzo, Paul A; Krishnan, Swathi; Trievel, Raymond C

Mapping the Energetics of Water–Protein and Water–Ligand Interactions with the “Natural” HINT Forcefield: Predictive Tools for Characterizing the Roles of Water in Biomolecules
score: 2.6214024, Journal of Molecular Biology, 2006, Amadasi, Alessio et. al.

Transcription regulation in thermophilic Bacteria: high resolution contact probing of Bacillus stearothermophilus and Thermotoga neapolitana arginine repressor-operator interactions 1 1 Edited by M. Yaniv
score: 2.618398, Journal of Molecular Biology, 2002, Song, Hui et. al.

Visualizing Group II Intron Catalysis through the Stages of Splicing
score: 2.618169, Cell, 2012, Marcia, Marco; Pyle, Anna Marie

Structure of an isolated unglycosylated antibody C H 2 domain
score: 2.6180657, Acta Crystallographica Section D: Biological Crystallography, 2008, Prabakaran, Ponraj et. al.

Comparative Dynamics of NMDA- and AMPA-Glutamate Receptor N-Terminal Domains
score: 2.6179057, Structure, 2012, Dutta, Anindita et. al.

Comparative Dynamics of NMDA- and AMPA-Glutamate Receptor N-Terminal Domains
score: 2.6179057, Structure, 2012, Dutta, Anindita et. al.

Novel reactions catalysed by antibodies
score: 2.6173302, Current Opinion in Structural Biology, 2000, Golinelli-Pimpaneau, Béatrice

Structure-based Design of a Second-generation Lyme Disease Vaccine Based on a C-terminal Fragment of Borrelia burgdorferi OspA
score: 2.6158235, Journal of Molecular Biology, 2005, Koide, Shohei et. al.

The fine structure of two DNA dodecamers containing the cAMP responsive element sequence and its inverse
score: 2.6139091, Journal of Molecular Biology, 1992, Mauffret, O. et. al.

Recent advances in the structural mechanisms of DNA glycosylases
score: 2.6128082, BBA - Proteins and Proteomics, 2013, Brooks, Sonja C. et. al.

Recent advances in the structural mechanisms of DNA glycosylases
score: 2.6128082, BBA - Proteins and Proteomics, 2013, Brooks, Sonja C. et. al.

Loop Conformation and Dynamics of the Escherichia coli HPPK Apo-Enzyme and Its Binary Complex with MgATP
score: 2.6118668, Biophysical Journal, 2005, Yang, Rong; Lee, Matthew C.; Yan, Honggao; Duan, Yong

Backbone Dynamics and Global Effects of an Activating Mutation in Minimized Mtu RecA Inteins
score: 2.6105144, Journal of Molecular Biology, 2010, Du, Zhenming et. al.

Proprotein Convertase Models based on the Crystal Structures of Furin and Kexin: Explanation of their Specificity
score: 2.6094725, Journal of Molecular Biology, 2005, Henrich, Stefan et. al.

Structure of a Glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface
score: 2.6092257, Molecular Cell, 2012, Duda, David M. et. al.

Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation
score: 2.6084761, Structure, 2012, Bunney, Tom D. et. al.

Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation
score: 2.6084761, Structure, 2012, Bunney, Tom D. et. al.

Solution structure, conformational dynamics, and CD4-induced activation in full-length, glycosylated, monomeric HIV gp120.
score: 2.6082325, Journal of virology, 2012, Guttman, Miklos et. al.

Crystallization of Escherichia coli catabolite gene activator protein with its DNA binding site
score: 2.6065042, Journal of Molecular Biology, 1990, Schultz, Steve C.; Shields, George C.; Steitz, Thomas A.

Design, Production and Molecular Structure of a New Family of Artificial Alpha-helicoidal Repeat Proteins (αRep) Based on Thermostable HEAT-like Repeats
score: 2.6060602, Journal of Molecular Biology, 2010, Urvoas, Agathe et. al.

Ta 6Br 12 2+, a tool for phase determination of large biological assemblies by X-ray crystallography 1 1 Edited by K.Nagai
score: 2.6058241, Journal of Molecular Biology, 1997, Knäblein, Jörg et. al.

Structural and biophysical characterization of an antimicrobial peptide chimera comprised of lactoferricin and lactoferrampin
score: 2.6056362, BBA - Biomembranes, 2012, Haney, Evan F. et. al.

Design and NMR studies of cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH.
score: 2.6027097, Chemical biology & drug design, 2011, Leone, Marilisa et. al.

Lipases and esterases: a review of their sequences, structure and evolution
score: 2.6018329, Biotechnology Annual Review, 1995, Anthonsen, Henrik W. et. al.

Lipases and esterases: a review of their sequences, structure and evolution
score: 2.6018329, Biotechnology Annual Review, 1995, Anthonsen, Henrik W. et. al.

Insights into the molecular basis of thermal stability from the structure determination of Pyrococcus furiosus gluatamate dehydrogenase
score: 2.6009018, FEMS Microbiology Reviews, 1996, Rice, D.W. et. al.

Automated protein-ligand crystallography for structure-based drug design.
score: 2.6003186, ChemMedChem, 2006, Mooij, Wijnand T M et. al.

Flexibility of EF-hand motifs: structural and thermodynamic studies of Calcium Binding Protein-1 from Entamoeba histolytica with Pb 2+ , Ba 2+ , and Sr 2+
score: 2.5994745, BMC Biophysics, 2012, Kumar, Shivesh et. al.

The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins
score: 2.5989828, Current Opinion in Structural Biology, 2009, Hiller, Sebastian; Wagner, Gerhard

Characterisation of the Interaction of the C-Terminus of the Dopamine D2 Receptor with Neuronal Calcium Sensor-1
score: 2.5987105, PLoS ONE, 2011, Lian, Lu-Yun et. al.

Substrate-dependent millisecond domain motions in DNA polymerase β
score: 2.5984522, Journal of Molecular Biology, 2012, Berlow, Rebecca B. et. al.

Sequence-specific binding of single-stranded RNA: is there a code for recognition?
score: 2.5981847, Nucleic Acids Research, 2006, Auweter, Sigrid D. et. al.

Identification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase V by structural and functional studies
score: 2.5967802, Nucleic Acids Research, 2012, Rajan, Rakhi et. al.

Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
score: 2.5936176, Structure, 2012, Laughlin, John D. et. al.

Bacterial phosphatidylinositol-specific phospholipase C: structure, function, and interaction with lipids
score: 2.5935899, BBA - Molecular and Cell Biology of Lipids, 1999, Griffith, O.Hayes; Ryan, Margret

The Escherichia coli large ribosomal subunit at 7.5 Å resolution
score: 2.5929588, Structure, 1999, Matadeen, Rishi et. al.

QM methods in structure based design: Utility in probing protein–ligand interactions
score: 2.5924036, Journal of Molecular Graphics and Modelling, 2010, Gleeson, M. Paul; Hannongbua, Supa; Gleeson, Duangkamol

Characterization of the binding interface between ubiquitin and class I human ubiquitin-conjugating enzyme 2b by multidimensional heteronuclear NMR spectroscopy in solution 1 1 Edited by P. E. Wright
score: 2.5912923, Journal of Molecular Biology, 1999, Miura, Takaaki et. al.

Active-site Properties of the Oxidized and Reduced C-terminal Domain of DsbD Obtained by NMR Spectroscopy
score: 2.5912813, Journal of Molecular Biology, 2007, Mavridou, Despoina A.I. et. al.

Structural characterization of S100A15 reveals a novel zinc coordination site among S100 proteins and altered surface chemistry with functional implications for receptor binding
score: 2.590747, BMC Structural Biology, 2012, Murray, Jill I et. al.

Crystal structure of the antigen-binding fragment of the murine anti-arsonate monoclonal antibody 36-71 at 2.9-A resolution.
score: 2.5898409, Proceedings of the National Academy of Sciences of the United States of America, 1990, Rose, D R et. al.

RNA tertiary interactions in the large ribosomal subunit: the A-minor motif.
score: 2.5889281, Proceedings of the National Academy of Sciences of the United States of America, 2001, Nissen, P; Ippolito, J A; Ban, N; Moore, P B; Steitz, T A

Protein thermostability above 100 degreesC: a key role for ionic interactions.
score: 2.587913, Proceedings of the National Academy of Sciences of the United States of America, 1998, Vetriani, C et. al.

Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site
score: 2.5878329, Archives of Biochemistry and Biophysics, 2013, Sharma, Pradeep et. al.

Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site
score: 2.5878329, Archives of Biochemistry and Biophysics, 2013, Sharma, Pradeep et. al.

West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody.
score: 2.5871388, Proceedings of the National Academy of Sciences of the United States of America, 2006, Kaufmann, Bärbel et. al.

Discovery and development of heat shock protein 90 inhibitors
score: 2.5870925, Bioorganic & Medicinal Chemistry, 2009, Taldone, Tony; Sun, Weilin; Chiosis, Gabriela

Hydrogen Exchange Solvent Protection by an ATP Analogue Reveals Conformational Changes in ERK2 upon Activation
score: 2.5867498, Journal of Molecular Biology, 2005, Lee, Thomas et. al.

Characterizing the Use of Perdeuteration in NMR Studies of Large Proteins: 13C, 15N and 1H Assignments of Human Carbonic Anhydrase II
score: 2.5853298, Journal of Molecular Biology, 1996, Venters, Ronald A. et. al.

Rational proteomics V: Structure-based mutagenesis has revealed key residues responsible for substrate recognition and catalysis by the dehydrogenase and isomerase activities in human 3β-hydroxysteroid dehydrogenase/isomerase type 1
score: 2.5845215, Journal of Steroid Biochemistry and Molecular Biology, 2006, Pletnev, Vladimir Z. et. al.

Structure of the utrophin actin-binding domain bound to F-actin reveals binding by an induced fit mechanism 1 1 Edited by M. F. Moody
score: 2.5844886, Journal of Molecular Biology, 2000, Moores, Carolyn A; Keep, Nicholas H; Kendrick-Jones, John

Fiber Diffraction Data Indicate a Hollow Core for the Alzheimer's Aβ 3-Fold Symmetric Fibril
score: 2.5837982, Journal of Molecular Biology, 2012, McDonald, Michele et. al.

Structure and backbone dynamics of a microcrystalline metalloprotein by solid-state NMR.
score: 2.5836218, Proceedings of the National Academy of Sciences of the United States of America, 2012, Knight, Michael J et. al.

Murine leukemia virus reverse transcriptase: Structural comparison with HIV-1 reverse transcriptase
score: 2.5833713, Virus Research, 2008, Coté, Marie L.; Roth, Monica J.

Structural effects of framework mutations on a humanized anti-lysozyme antibody.
score: 2.5832011, Journal of immunology (Baltimore, Md. : 1950), 2001, Holmes, M A; Buss, T N; Foote, J

The design, synthesis and biological evaluation of PIM kinase inhibitors
score: 2.582804, Bioorganic & Medicinal Chemistry Letters, 2012, Tsuhako, Amy Lew et. al.

The crystal structures of 3-TAPAP in complexes with the urokinase-type plasminogen activator and picrate
score: 2.5823584, Bioorganic & Medicinal Chemistry Letters, 2006, Żesławska, Ewa et. al.

How the lipid-free structure of the N-terminal truncated human apoA-I converts to the lipid-bound form: new insights from NMR and X-ray structural comparison
score: 2.5820379, FEBS Letters, 2002, Wang, Guangshun

NMR-derived solution structure of SUMO from Drosophila melanogaster (dSmt3).
score: 2.5818777, Proteins, 2009, Kumar, Dinesh et. al.

The Importance of Electrostatic Potential in The Interaction of Sweet Proteins with the Sweet Taste Receptor
score: 2.5812433, Journal of Molecular Biology, 2006, Esposito, Veronica et. al.

Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones.
score: 2.5812341, Proceedings of the National Academy of Sciences of the United States of America, 2011, Zhuravleva, Anastasia; Gierasch, Lila M

Side-chain conformations in an unfolded protein: χ 1 distributions in denatured hen lysozyme determined by heteronuclear 13C, 15N NMR spectroscopy 1 1 Edited by A. R. Fersht
score: 2.581115, Journal of Molecular Biology, 1999, Hennig, Mirko et. al.

REFMAC 5 for the refinement of macromolecular crystal structures
score: 2.580568, Acta Crystallographica Section D: Biological Crystallography, 2011, Murshudov, Garib N. et. al.

TROSY-NMR Studies of the 91 kDa TRAP Protein Reveal Allosteric Control of a Gene Regulatory Protein by Ligand-altered Flexibility
score: 2.5805348, Journal of Molecular Biology, 2002, McElroy, Craig et. al.

Small angle X-ray scattering as a complementary tool for high-throughput structural studies.
score: 2.5784843, Biopolymers, 2011, Grant, Thomas D et. al.

NMR Techniques for Identifying the Interface of a Larger Protein–Protein Complex: Cross-Saturation and Transferred Cross-Saturation Experiments
score: 2.5762772, Methods in Enzymology, 2005, Shimada, Ichio

NMR Techniques for Identifying the Interface of a Larger Protein–Protein Complex: Cross-Saturation and Transferred Cross-Saturation Experiments
score: 2.5762772, Methods in Enzymology, 2005, Shimada, Ichio

Structures of human proteinase 3 and neutrophil elastase--so similar yet so different.
score: 2.5754828, The FEBS journal, 2010, Hajjar, Eric et. al.

Structural Similarity between the Prion Domain of HET-s and a Homologue Can Explain Amyloid Cross-Seeding in Spite of Limited Sequence Identity
score: 2.5751566, Journal of Molecular Biology, 2010, Wasmer, Christian et. al.

Purification, crystallization, and properties of F 1-ATPase complexes from the thermoalkaliphilic Bacillus sp. strain TA2.A1
score: 2.5742869, Journal of Structural Biology, 2005, Stocker, Achim et. al.

New crystal structures of nucleic acids and their complexes
score: 2.5741885, Current Opinion in Structural Biology, 1995, Wahl, Markus C; Sundaralingam, Muttaiya

The active site structure of quinohemoprotein amine dehydrogenase inhibited by p-nitrophenylhydrazine
score: 2.5741826, BBA - Proteins and Proteomics, 2003, Satoh, Atsuko et. al.

Molecular Basis for Recognition of Dilysine Trafficking Motifs by COPI
score: 2.5736407, Developmental Cell, 2012, Jackson, Lauren P. et. al.

Enamino-oxindole HIV protease inhibitors
score: 2.5734252, Bioorganic & Medicinal Chemistry Letters, 2012, Eissenstat, Michael et. al.

Enamino-oxindole HIV protease inhibitors
score: 2.5734252, Bioorganic & Medicinal Chemistry Letters, 2012, Eissenstat, Michael et. al.

Enamino-oxindole HIV protease inhibitors
score: 2.5734252, Bioorganic & Medicinal Chemistry Letters, 2012, Eissenstat, Michael et. al.

The structural genomics experimental pipeline: insights from global target lists.
score: 2.5719264, Proteins, 2004, O'Toole, Nicholas et. al.

Structure of the Vibrio cholerae Type IVb Pilus and Stability Comparison with the Neisseria gonorrhoeae Type IVa Pilus
score: 2.5715012, Journal of Molecular Biology, 2012, Li, Juliana; Egelman, Edward H.; Craig, Lisa

Probing Catalytically Essential Domain Orientation in Histidine Kinase EnvZ by Targeted Disulfide Crosslinking
score: 2.5710362, Journal of Molecular Biology, 2003, Cai, Sheng-Jian et. al.

Structure and mechanism of Escherichia coli pyridoxine 5′-phosphate oxidase
score: 2.5708759, BBA - Proteins and Proteomics, 2003, di Salvo, Martino L. et. al.

The Staphylococcus aureus extracellular adherence protein (Eap) adopts an elongated but structured conformation in solution.
score: 2.5704543, Protein science : a publication of the Protein Society, 2007, Hammel, Michal et. al.

The Hexamer Structure of the Rift Valley Fever Virus Nucleoprotein Suggests a Mechanism for its Assembly into Ribonucleoprotein Complexes
score: 2.5703231, PLoS Pathogens, 2011, Ferron, François et. al.

The Refined Crystal Structure of Hexon, the Major Coat Protein of Adenovirus Type 2, at 2·9 Å Resolution
score: 2.5700515, Journal of Molecular Biology, 1994, Athappily, Francis K. et. al.

Structural consequences of sequence patterns in the fingerprint region of the nucleotide binding fold
score: 2.5697437, Journal of Molecular Biology, 1992, Baker, Patrick J. et. al.

Functional modulation of a protein folding landscape via side-chain distortion.
score: 2.5690654, Proceedings of the National Academy of Sciences of the United States of America, 2012, Kelch, Brian A; Salimi, Neema L; Agard, David A

Higher-Order Architecture of Cell Adhesion Mediated by Polymorphic Synaptic Adhesion Molecules Neurexin and Neuroligin
score: 2.568616, Cell Reports, 2012, Tanaka, Hiroki et. al.

Higher-Order Architecture of Cell Adhesion Mediated by Polymorphic Synaptic Adhesion Molecules Neurexin and Neuroligin
score: 2.568616, Cell Reports, 2012, Tanaka, Hiroki et. al.

Solution Structure and Phylogenetics of Prod1, a Member of the Three-Finger Protein Superfamily Implicated in Salamander Limb Regeneration
score: 2.568599, PLoS ONE, 2009, Garza-Garcia, Acely et. al.

Substitution of aspartic acid with glutamic acid increases the unfolding transition temperature of a protein
score: 2.5683881, Biochemical and Biophysical Research Communications, 2004, Lee, Duck Yeon; Kim, Kyeong-Ae; Yu, Yeon Gyu; Kim, Key-Sun

C-H..O hydrogen bonds in minor groove of A-tracts in DNA double helices 1 1 Edited by B. Honig
score: 2.5682938, Journal of Molecular Biology, 1999, Ghosh, Anirban; Bansal, Manju

The Survival Motor Neuron Protein Forms Soluble Glycine Zipper Oligomers
score: 2.5678471, Structure, 2012, Martin, Renee et. al.

The Survival Motor Neuron Protein Forms Soluble Glycine Zipper Oligomers
score: 2.5678471, Structure, 2012, Martin, Renee et. al.

Conserved β-Hairpin Recognition by the GYF Domains of Smy2 and GIGYF2 in mRNA Surveillance and Vesicular Transport Complexes
score: 2.5670886, Structure, 2010, Ash, Miriam-Rose et. al.

High-throughput crystallography for lead discovery in drug design.
score: 2.5666285, Nature reviews. Drug discovery, 2002, Blundell, Tom L; Jhoti, Harren; Abell, Chris

A Comprehensive Alanine Scanning Mutagenesis of the Escherichia coli Transcriptional Activator SoxS: Identifying Amino Acids Important for DNA Binding and Transcription Activation
score: 2.5665777, Journal of Molecular Biology, 2002, Griffith, Kevin L.; Wolf, Richard E.

A tale of two secondary structure elements: when a β-hairpin becomes an α-helix 1 1 Edited by A. R. Fersht
score: 2.5665491, Journal of Molecular Biology, 1999, Cregut, David et. al.

Novel mechanism of regulation of the non-receptor protein tyrosine kinase csk: insights from NMR mapping studies and site-directed mutagenesis 1 1 Edited by M. F. Summers
score: 2.5664825, Journal of Molecular Biology, 2001, Shekhtman, Alexander et. al.

Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
score: 2.5640009, Bioorganic & Medicinal Chemistry, 2012, Yoshida, Tomohiro et. al.

Inhibitors of acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 1: Hit to lead evaluation of a novel arylsulfonamide series
score: 2.5637545, Bioorganic & Medicinal Chemistry Letters, 2012, Green, Oluyinka M. et. al.

Structure of a novel PTH-related peptide hPTH' and its interaction with the PTH receptor.
score: 2.5633423, Journal of peptide science : an official publication of the European Peptide Society, 2012, Lin, Kejiang et. al.

Three-dimensional solution structure of the pleckstrin homology domain from dynamin
score: 2.5631491, Current Biology, 1994, Downing, A.Kristina et. al.

Three-dimensional solution structure of the pleckstrin homology domain from dynamin
score: 2.5631491, Current Biology, 1994, Downing, A.Kristina et. al.

A Single Destabilizing Mutation (F9S) Promotes Concerted Unfolding of an Entire Globular Domain in γS-Crystallin
score: 2.5624237, Journal of Molecular Biology, 2010, Lee, Soojin et. al.

Disparate peptide-dependent thymic selection outcomes in beta2M-deficient mice versus TAP-1-deficient mice: implications for repertoire formation.
score: 2.5616603, European journal of immunology, 2003, Sasada, Tetsuro et. al.

The dynamical response of hen egg white lysozyme to the binding of a carbohydrate ligand.
score: 2.5604498, Protein science : a publication of the Protein Society, 2012, Moorman, Veronica R; Valentine, Kathleen G; Wand, A Joshua

Structural investigation of the ligand binding domain of the zebrafish VDR in complexes with 1α,25(OH) 2D 3 and Gemini: purification, crystallization and preliminary X-ray diffraction analysis
score: 2.5596504, Journal of Steroid Biochemistry and Molecular Biology, 2004, Ciesielski, Fabrice et. al.

A branch and bound algorithm for protein structure refinement from sparse NMR data sets 1 1 Edited by F. Cohen
score: 2.559606, Journal of Molecular Biology, 1999, Standley, Daron M. et. al.

The structure of membrane associated proteins in eicosanoid and glutathione metabolism as determined by electron crystallography
score: 2.5588853, Current Opinion in Structural Biology, 2007, Hebert, Hans; Jegerschöld, Caroline

Structure–activity relationships and key structural feature of pyridyloxybenzene-acylsulfonamides as new, potent, and selective peroxisome proliferator-activated receptor (PPAR) γ Agonists
score: 2.5588237, Bioorganic & Medicinal Chemistry, 2012, Rikimaru, Kentaro et. al.

Crystal Structure of the β 2 Adrenergic Receptor-Gs protein complex
score: 2.5570681, Nature, 2011, Rasmussen, Søren G.F. et. al.

In silico screening reveals structurally diverse, nanomolar inhibitors of NQO2 that are functionally active in cells and can modulate NF-κB signaling.
score: 2.5563667, Molecular cancer therapeutics, 2012, Nolan, Karen A et. al.

The Mechanics of Translocation: A Molecular “Spring-and-Ratchet” System
score: 2.5563108, Structure, 2008, Moran, Stephen J. et. al.

X-Ray Diffraction Experiment:The Last Experiment in the Structure Elucidation Process
score: 2.5549764, Advances in Protein Chemistry and Structural Biology, 2009, Chruszcz, Maksymilian et. al.

X-Ray Diffraction Experiment:The Last Experiment in the Structure Elucidation Process
score: 2.5549764, Advances in Protein Chemistry and Structural Biology, 2009, Chruszcz, Maksymilian et. al.

Validation of the single-stranded channel conformation of gramicidin A by solid-state NMR.
score: 2.5540335, Proceedings of the National Academy of Sciences of the United States of America, 1999, Kovacs, F; Quine, J; Cross, T A

Crystallisation of Wild-Type and Variant Forms of a Recombinant Plant Enzyme β- d -Glucan Glucohydrolase from Barley ( Hordeum vulgare L.) and Preliminary X-ray Analysis
score: 2.5530889, International Journal of Molecular Sciences, 2010, Luang, Sukanya et. al.

Perspectives on protein crystallisation
score: 2.5519806, Progress in Biophysics and Molecular Biology, 2009, Ochi, Takashi et. al.

The Xplor-NIH NMR molecular structure determination package
score: 2.5516222, Journal of Magnetic Resonance, 2003, Schwieters, Charles D et. al.

Molecular Basis for a Protein-Mediated DNA-Bridging Mechanism that Functions in Condensation of the E. coli Chromosome
score: 2.5498935, Molecular Cell, 2012, Dupaigne, Pauline et. al.

Molecular Basis for a Protein-Mediated DNA-Bridging Mechanism that Functions in Condensation of the E. coli Chromosome
score: 2.5498935, Molecular Cell, 2012, Dupaigne, Pauline et. al.

Structural basis for gibberellin recognition by its receptor GID1.
score: 2.5491186, Nature, 2008, Shimada, Asako et. al.

Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888
score: 2.5488255, Molecular Immunology, 2012, Obmolova, Galina et. al.

Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888
score: 2.5488255, Molecular Immunology, 2012, Obmolova, Galina et. al.

Molecular Mechanism Underlying the Thermal Stability and pH-induced Unfolding of CHABII
score: 2.5483852, Journal of Molecular Biology, 2005, Wei, Zheng; Song, Jianxing

FMS Kinase Inhibitors: Current Status and Future Prospects.
score: 2.546581, Medicinal research reviews, 2012, El-Gamal, Mohammed I et. al.

Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.
score: 2.5463513, Nature structural & molecular biology, 2012, Chen, Shoudeng et. al.

Aldose and aldehyde reductases: correlation of molecular modeling and mass spectrometric studies on the binding of inhibitors to the active site.
score: 2.5457354, Proteins, 2000, El-Kabbani, O et. al.

Crystallographically Mapped Ligand Binding Differs in High and Low IgE Binding Isoforms of Birch Pollen Allergen Bet v 1
score: 2.5453068, Journal of Molecular Biology, 2012, Kofler, Stefan et. al.

An efficient synthesis of argifin: A natural product chitinase inhibitor with chemotherapeutic potential
score: 2.5437633, Bioorganic & Medicinal Chemistry Letters, 2005, Dixon, Mark J. et. al.

Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Parallel synthesis, molecular modelling and structure–activity relationship studies on O-[2-(hetero)arylethyl]- N-phenylthiocarbamates
score: 2.5436069, Bioorganic & Medicinal Chemistry, 2008, Cesarini, Sara et. al.

GTPase Catalysis by Ras and Other G-proteins: Insights from Substrate Directed SuperImposition
score: 2.5432292, Journal of Molecular Biology, 2003, Kosloff, Mickey; Selinger, Zvi

A Secondary Xylan-binding Site Enhances the Catalytic Activity of a Single-domain Family 11 Glycoside Hydrolase
score: 2.5428717, Journal of Molecular Biology, 2007, Ludwiczek, Martin L. et. al.

The Dynamic Structure of Thrombin in Solution
score: 2.5421932, Biophysical Journal, 2012, Fuglestad, Brian et. al.

Messages from ultrahigh resolution crystal structures
score: 2.5421149, Current Opinion in Structural Biology, 1998, Longhi, Sonia; Czjzek, Mirjam; Cambillau, Christian

Crystal structure of a novel dimer form of FlgD from P. aeruginosa PAO1.
score: 2.5419938, Proteins, 2011, Zhou, Hua et. al.

Nonspecific Recognition Is Achieved in Pot1pC through the Use of Multiple Binding Modes
score: 2.5417773, Structure, 2013, Dickey, Thayne H.; McKercher, Marissa A.; Wuttke, Deborah S.

Solution structure of β 2-microglobulin and insights into fibrillogenesis
score: 2.541286, BBA - Proteins and Proteomics, 2005, Esposito, Gennaro et. al.

Observation of Decreased Radiation Damage at Higher Dose Rates in Room Temperature Protein Crystallography
score: 2.5399457, Structure, 2007, Southworth-Davies, Robert J. et. al.

Asymmetry in the Triple Helix of Collagen-like Heterotrimers Confirms that External Bonds Stabilize Collagen Structure
score: 2.5382601, Journal of Molecular Biology, 2003, Slatter, David A; Miles, Christopher A; Bailey, Allen J

In-Silico docking of HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate
score: 2.5379503, Retrovirology, 2007, Savarino, Andrea

Crystallization and initial crystallographic results for pepstatin A inhibited bovine cathepsin D
score: 2.5376956, Journal of Molecular Biology, 1992, Bieber, Frank et. al.

Identification of potent ITK inhibitors through focused compound library design including structural information
score: 2.5372986, Bioorganic & Medicinal Chemistry Letters, 2010, Herdemann, Matthias et. al.

NMR Characterization of Full-length Farnesylated and Non-farnesylated H-Ras and its Implications for Raf Activation
score: 2.5372612, Journal of Molecular Biology, 2004, Thapar, Roopa; Williams, Jason G.; Campbell, Sharon L.

Overlapping transport and chaperone-binding functions within a bacterial twin-arginine signal peptide.
score: 2.5368692, Molecular microbiology, 2012, Grahl, Sabine et. al.

Standard conformations for the canonical structures of immunoglobulins 1 1 Edited by I. A. Wilson
score: 2.5362651, Journal of Molecular Biology, 1997, Al-Lazikani, Bissan; Lesk, Arthur M; Chothia, Cyrus

Structural identification of cation binding pockets in the plasma membrane proton pump.
score: 2.5355682, Proceedings of the National Academy of Sciences of the United States of America, 2010, Ekberg, Kira et. al.

Structures of orbivirus VP7: implications for the role of this protein in the viral life cycle
score: 2.5348654, Structure, 1997, Basak, Ajit K et. al.

The architecture of parallel β-helices and related folds
score: 2.5347055, Progress in Biophysics and Molecular Biology, 2001, Jenkins, John; Pickersgill, Richard

HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail
score: 2.5343833, Structure, 2012, Rowell, John P. et. al.

HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail
score: 2.5343833, Structure, 2012, Rowell, John P. et. al.

The application of hydrogen bonding analysis in X-ray crystallography to help orientate asparagine, glutamine and histidine side chains.
score: 2.5342404, Protein engineering, 1995, McDonald, I K; Thornton, J M

RETRACTED: Structure of the Parathyroid Hormone Receptor C Terminus Bound to the G-Protein Dimer Gβ 1γ 2
score: 2.5336635, Structure, 2008, Johnston, Christopher A. et. al.

Structure–function relationships in Anabaena ferredoxin/ferredoxin:NADP + reductase electron transfer: insights from site-directed mutagenesis, transient absorption spectroscopy and X-ray crystallography
score: 2.5322238, BBA - Bioenergetics, 2002, Hurley, John K. et. al.

Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface
score: 2.5314643, Nature Communications, 2013, Kimlicka, Lynn et. al.

The advantages and limitations of protein crystal structures
score: 2.5312283, Trends in Pharmacological Sciences, 2005, Acharya, K. Ravi; Lloyd, Matthew D.

Bridging the solution divide: comprehensive structural analyses of dynamic RNA, DNA, and protein assemblies by small-angle X-ray scattering
score: 2.5302952, Current Opinion in Structural Biology, 2010, Rambo, Robert P; Tainer, John A

Rebuilt 3D structure of the chloroplast f1 ATPase-tentoxin complex.
score: 2.5283681, Proteins, 2002, Minoletti, Claire et. al.

Scrunching During DNA Repair Synthesis
score: 2.5283088, Nature structural & molecular biology, 2009, Garcia-Diaz, Miguel et. al.

Three-Dimensional Structure of a DNA Repair Enzyme, 3-Methyladenine DNA Glycosylase II, from Escherichia coli
score: 2.5277639, Cell, 1996, Yamagata, Yuriko et. al.

Rapid-access, high-throughput synchrotron crystallography for drug discovery
score: 2.5276385, Trends in Pharmacological Sciences, 2012, Wasserman, Stephen R. et. al.

The intrinsically disordered C-terminal domain of the measles virus nucleoprotein interacts with the C-terminal domain of the phosphoprotein via two distinct sites and remains predominantly unfolded.
score: 2.5276232, Protein science : a publication of the Protein Society, 2005, Bourhis, Jean-Marie et. al.

Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms
score: 2.5274851, Toxicology, 2008, Sim, Edith et. al.

The interrelationships of side-chain and main-chain conformations in proteins
score: 2.5259438, Progress in Biophysics and Molecular Biology, 2001, Chakrabarti, Pinak; Pal, Debnath

Common Interruptions in the Repeating Tripeptide Sequence of Non-fibrillar Collagens: Sequence Analysis and Structural Studies on Triple-helix Peptide Models
score: 2.5254468, Journal of Molecular Biology, 2008, Thiagarajan, Geetha et. al.

Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing
score: 2.5244247, Structure, 2012, Xu, Zhiwen et. al.

Glutamine 53 is a Gatekeeper Residue in the FK506 Binding Protein
score: 2.5235897, Journal of Molecular Biology, 2002, Korepanova, Alla; Douglas, Chanel; Logan, Timothy M.

Caged protein prenyltransferase substrates: tools for understanding protein prenylation.
score: 2.523275, Chemical biology & drug design, 2008, DeGraw, Amanda J et. al.

3D-Structures of the lipase from Rhizomucor miehei at different temperatures and computer modelling of a complex of the lipase with trilaurylglycerol
score: 2.522582, Journal of Biotechnology, 1993, Vasel, Birger et. al.

Structural comparison of tRNA m 1 A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions
score: 2.5219467, BMC Structural Biology, 2011, Guelorget, Amandine et. al.

Structure and Dynamics of Ca 2 + -Binding Domain 1 of the Na + /Ca 2 + Exchanger in the Presence and in the Absence of Ca 2 +
score: 2.5218894, Journal of Molecular Biology, 2008, Johnson, Eric et. al.

Macrocyclic peptidomimetic inhibitors of β-secretase (BACE): First X-ray structure of a macrocyclic peptidomimetic-BACE complex
score: 2.5212772, Bioorganic & Medicinal Chemistry Letters, 2006, Rojo, Isabel et. al.

Auto-induction and purification of a Bacillus subtilis transglutaminase (Tgl) and its preliminary crystallographic characterization
score: 2.5208216, Protein Expression and Purification, 2008, Plácido, Diana et. al.

Towards the structure-based design of oligonucleotide therapeutics
score: 2.5208144, Advances in Enzyme Regulation, 1998, Egli, Martin

Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide
score: 2.5171577, Bioorganic & Medicinal Chemistry Letters, 2004, Abbate, Francesco et. al.

Dynamic Interactions between Clathrin and Locally Structured Elements in a Disordered Protein Mediate Clathrin Lattice Assembly
score: 2.5158151, Journal of Molecular Biology, 2010, Zhuo, Yue et. al.

Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate.
score: 2.5144123, Proceedings of the National Academy of Sciences of the United States of America, 2012, Ha, Byung Hak et. al.

Protein–lipid interactions in the purple bacterial reaction centre
score: 2.5124744, BBA - Biomembranes, 2002, Jones, Michael R. et. al.

The structural basis of transferrin sequestration by transferrin-binding protein B.
score: 2.5123919, Nature structural & molecular biology, 2012, Calmettes, Charles et. al.

Crystallization and preliminary crystal structure of the complex of 17β-hydroxysteroid dehydrogenase with a dual-site inhibitor
score: 2.5121943, Journal of Steroid Biochemistry and Molecular Biology, 1999, Zhu, Dao-Wei et. al.

Binding affinities and geometries of various metal ligands in peptide deformylase inhibitors
score: 2.5118781, Biophysical Chemistry, 2002, Madison, V et. al.

Atomic resolution structures of bacteriorhodopsin photocycle intermediates: the role of discrete water molecules in the function of this light-driven ion pump
score: 2.5106808, BBA - Bioenergetics, 2000, Luecke, Hartmut

The Crystal Structure of the N-terminal SH3 Domain of Grb2
score: 2.51051, Journal of Molecular Biology, 1995, Guruprasad, L. et. al.

The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity.
score: 2.5100506, The EMBO journal, 2006, Okorokov, Andrei L et. al.

Structure, Dynamics and Folding of an Immunoglobulin Domain of the Gelation Factor (ABP-120) from Dictyostelium discoideum
score: 2.509886, Journal of Molecular Biology, 2009, Hsu, Shang-Te Danny et. al.

New Active HIV-1 Protease Inhibitors Derived from 3-Hexanol: Conformation Study of the Free Inhibitors in Crystalline State and in Complex with the Enzyme.
score: 2.5086145, Chemical biology & drug design, 2012, Ziółkowska, Natasza E et. al.

Crystallization of MAP kinases
score: 2.5084578, Methods, 2006, Lee, Seung-Jae; Zhou, Tianjun; Goldsmith, Elizabeth J.

Solution Structure of the Complex Formed between Human Complement C3d and Full-length Complement Receptor Type 2
score: 2.507515, Journal of Molecular Biology, 2008, Li, Keying et. al.

Isolation, characterization and biological activity of acidic phospholipase A 2 isoforms from Bothrops jararacussu snake venom
score: 2.5074387, Biochimie, 2003, Ketelhut, D.F.J et. al.

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer
score: 2.5068669, Cell, 2008, Waddington, Simon N. et. al.

Identification of a novel two component system in Thermotoga maritima. Complex stoichiometry and crystallization
score: 2.5066858, BBA - Proteins and Proteomics, 2007, Casino, Patricia et. al.

Structure of an Influenza Neuraminidase–Diabody Complex by Electron Cryomicroscopy and Image Analysis
score: 2.5055669, Journal of Molecular Biology, 2003, Rosenthal, Peter B.; Waddington, Lynne J.; Hudson, Peter J.

Structural Insights into the Dual Strategy of Recognition by Peptidoglycan Recognition Protein, PGRP-S: Structure of the Ternary Complex of PGRP-S with Lipopolysaccharide and Stearic Acid
score: 2.5053685, PLoS ONE, 2013, Sharma, Pradeep et. al.

Functional and Structural Characterization of the Arylamine N-Acetyltransferase from the Opportunistic Pathogen Nocardia farcinica
score: 2.5053235, Journal of Molecular Biology, 2008, Martins, Marta et. al.

Application of 1H NMR chemical shifts to measure the quality of protein structures
score: 2.5052988, Journal of Molecular Biology, 1995, Williamson, Michael P.; Kikuchi, Jun; Asakura, Tetsuo

Two Structural Transitions in Membrane Pore Formation by Pneumolysin, the Pore-Forming Toxin of Streptococcus pneumoniae
score: 2.5051922, Cell, 1999, Gilbert, Robert J.C et. al.

Comparison of Fragments Comprising the First Two Helices of the Human Y4 and the Yeast Ste2p G-Protein-Coupled Receptors
score: 2.5043875, Biophysical Journal, 2012, Shao, Xuan; Zou, Chao; Naider, Fred; Zerbe, Oliver

Genomics, evolution, and crystal structure of a new family of bacterial spore kinases.
score: 2.5043683, Proteins, 2010, Scheeff, Eric D et. al.

Structure and Mechanism of the CMR Complex for CRISPR-Mediated Antiviral Immunity
score: 2.5041238, Molecular Cell, 2012, Zhang, Jing et. al.

Structural basis for nucleotide exchange on G alpha i subunits and receptor coupling specificity.
score: 2.5036834, Proceedings of the National Academy of Sciences of the United States of America, 2007, Johnston, Christopher A; Siderovski, David P

Inhibitor binding changes domain mobility in the iron-sulfur protein of the mitochondrial bc1 complex from bovine heart.
score: 2.5035675, Proceedings of the National Academy of Sciences of the United States of America, 1998, Kim, H et. al.

Determination of Protein Backbone Structures from Residual Dipolar Couplings
score: 2.5009044, Methods in Enzymology, 2005, Prestegard, J.H.; Mayer, K.L.; Valafar, H.; Benison, G.C.

Determination of Protein Backbone Structures from Residual Dipolar Couplings
score: 2.5009044, Methods in Enzymology, 2005, Prestegard, J.H.; Mayer, K.L.; Valafar, H.; Benison, G.C.

Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family
score: 2.5006446, BBA - Proteins and Proteomics, 2004, Ma, Xueyan et. al.

The crystal structure of seleno-glutathione peroxidase from human plasma at 2.9 Å resolution 1 1 Edited by R. Huber
score: 2.5001374, Journal of Molecular Biology, 1997, Ren, Bin; Huang, Wenhu; Åkesson, Björn; Ladenstein, Rudolf

Crystals of a ternary complex of human immunodeficiency virus type 1 reverse transcriptase with a monoclonal antibody Fab fragment and double-stranded DNA diffract x-rays to 3.5-A resolution.
score: 2.4988121, Proceedings of the National Academy of Sciences of the United States of America, 1991, Jacobo-Molina, A et. al.

Structural basis of preferential binding of fucose-containing saccharide by the Caenorhabditis elegans galectin LEC-6.
score: 2.4986682, Glycobiology, 2013, Makyio, Hisayoshi et. al.

Protein engineering
score: 2.4986469, Current Opinion in Biotechnology, 1991,

Analyzing your complexes: structure of the quinol-fumarate reductase respiratory complex
score: 2.4985215, Current Opinion in Structural Biology, 2000, Iverson, Tina M et. al.

Structural insights into the dual-targeting mechanism of Nutlin-3
score: 2.4978524, Biochemical and Biophysical Research Communications, 2012, Shin, Jae-Sun et. al.

Structural insights into the dual-targeting mechanism of Nutlin-3
score: 2.4978524, Biochemical and Biophysical Research Communications, 2012, Shin, Jae-Sun et. al.

Structure of nogalamycin bound to a DNA hexamer.
score: 2.4971658, Proceedings of the National Academy of Sciences of the United States of America, 1990, Williams, L D et. al.

NMR Spectroscopy of the Ligand-Binding Core of Ionotropic Glutamate Receptor 2 Bound to 5-Substituted Willardiine Partial Agonists
score: 2.4956503, Journal of Molecular Biology, 2008, Fenwick, Michael K.; Oswald, Robert E.

Similarities between the spectrin SH3 domain denatured state and its folding transition state 1 1 Edited by A. R. Fersht
score: 2.4940306, Journal of Molecular Biology, 2000, Kortemme, Tanja et. al.

Two Carbohydrate Binding Sites in the H CC-domain of Tetanus Neurotoxin are Required for Toxicity
score: 2.4934515, Journal of Molecular Biology, 2003, Rummel, Andreas et. al.

Structural and biochemical studies of retroviral proteases
score: 2.4925953, Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology, 2000, Wlodawer, Alexander; Gustchina, Alla

Computational proteomics of biomolecular interactions in the sequence and structure space of the tyrosine kinome: deciphering the molecular basis of the kinase inhibitors selectivity.
score: 2.4925105, Proteins, 2007, Verkhivker, Gennady M

Structure-Based Design of Ricin Inhibitors
score: 2.4922015, Toxins, 2011, Jasheway, Karl et. al.

Conformational Variability of Chicken Cystatin
score: 2.4913215, Journal of Molecular Biology, 1993, Engh, Richard A. et. al.

Nonplanar peptide bonds in proteins are common and conserved but not biased toward active sites.
score: 2.4913212, Proceedings of the National Academy of Sciences of the United States of America, 2012, Berkholz, Donald S et. al.

Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions
score: 2.4905918, BMC Structural Biology, 2011, Jackson, Sean G et. al.

Modifications Modulate Anticodon Loop Dynamics and Codon Recognition of E. coli tRNAArg1,2
score: 2.4873802, Journal of Molecular Biology, 2012, Cantara, William A. et. al.

Determinants of backbone dynamics in native BPTI: cooperative influence of the 14–38 disulfide and the tyr35 side-chain 1 1 Edited by P. E. Wright
score: 2.4871601, Journal of Molecular Biology, 1998, Beeser, Scott A; Oas, Terrence G; Goldenberg, David P

Synergistic Applications of MD and NMR for the Study of Biological Systems
score: 2.48701, Journal of Biomedicine and Biotechnology, 2012, Fisette, Olivier et. al.

Preliminary crystallographic analysis of the breakage-reunion domain of the Escherichia coli DNA gyrase a protein
score: 2.4869401, Journal of Molecular Biology, 1990, Reece, Richard J. et. al.

Changes in zinc ligation promote remodeling of the active site in the zinc hydrolase superfamily 1 1 Edited by J. Thornton
score: 2.4869057, Journal of Molecular Biology, 2001, Wouters, Merridee A; Husain, Ahsan

Allosteric Network of cAMP-dependent Protein Kinase Revealed by Mutation of Tyr204 in the P+1 Loop
score: 2.4865466, Journal of Molecular Biology, 2005, Yang, Jie et. al.

Inhibition of carboxypeptidase A by excess zinc: analysis of the structural determinants by X-ray crystallography
score: 2.4855721, FEBS Letters, 1997, Gomez-Ortiz, Mariola et. al.

Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors
score: 2.485001, Bioorganic & Medicinal Chemistry Letters, 2009, Choi, Yongmun et. al.

Replication protein A 32 interacts through a similar binding interface with TIPIN, XPA, and UNG2
score: 2.4840995, International Journal of Biochemistry and Cell Biology, 2010, Ali, Seikh Imtiaz et. al.

The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b
score: 2.4833811, Structure(London, England:1993), 2012, Baumli, Sonja et. al.

Insights into Signal Transduction Revealed by the Low Resolution Structure of the FixJ Response Regulator
score: 2.4819341, Journal of Molecular Biology, 2002, Birck, Catherine et. al.

Structural and functional studies on Ycf12 (Psb30) and PsbZ-deletion mutants from a thermophilic cyanobacterium
score: 2.4818533, BBA - Bioenergetics, 2010, Takasaka, Kenji et. al.

Reversible Dimer Formation and Stability of the Anti-tumour Single-chain Fv Antibody MFE-23 by Neutron Scattering, Analytical Ultracentrifugation, and NMR and FT-IR Spectroscopy
score: 2.4817958, Journal of Molecular Biology, 2002, Lee, Yie Chia et. al.

One Fold with Many Functions: The Evolutionary Relationships between TIM Barrel Families Based on their Sequences, Structures and Functions
score: 2.4814452, Journal of Molecular Biology, 2002, Nagano, Nozomi; Orengo, Christine A; Thornton, Janet M

Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization
score: 2.4809174, Bioorganic & Medicinal Chemistry, 2012, Lecis, Daniele et. al.

Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization
score: 2.4809174, Bioorganic & Medicinal Chemistry, 2012, Lecis, Daniele et. al.

Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization
score: 2.4809174, Bioorganic & Medicinal Chemistry, 2012, Lecis, Daniele et. al.

Lac repressor—operator complex
score: 2.4806789, Current Opinion in Structural Biology, 1997, Kercher, Michele A; Lu, Ponzy; Lewis, Mitchell

NMR Reveals a Novel Glutaredoxin–Glutaredoxin Interaction Interface
score: 2.4795318, Journal of Molecular Biology, 2005, Noguera, Valerie et. al.

Structural basis of HutP-mediated transcription anti-termination
score: 2.4788605, Current Opinion in Structural Biology, 2006, Kumar, Penmetcha KR et. al.

Hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi as a target for structure-based inhibitor design: crystallization and inhibition studies with purine analogs.
score: 2.4785567, Antimicrobial agents and chemotherapy, 1997, Eakin, A E et. al.

Structure of the OSR1 kinase, a hypertension drug target.
score: 2.4779063, Proteins, 2008, Villa, Fabrizio et. al.

Cyclic olefin homopolymer-based microfluidics for protein crystallization and in situ X-ray diffraction
score: 2.4777152, Acta Crystallographica Section D: Biological Crystallography, 2009, Emamzadah, Soheila et. al.

Structural characterization of a conserved, calcium-dependent periplasmic protease from Legionella pneumophila.
score: 2.4773807, Journal of bacteriology, 2012, Chatterjee, Debashree et. al.

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy
score: 2.4772556, Molecular Cell, 2012, von Muhlinen, Natalia et. al.

Allostery in Hsp70 Chaperones Is Transduced by Subdomain Rotations
score: 2.4767622, Journal of Molecular Biology, 2009, Bhattacharya, Akash et. al.

The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study.
score: 2.4764602, Proceedings of the National Academy of Sciences of the United States of America, 1999, Groll, M et. al.

X-ray structural analysis of compensating mutations at the barnase-barstar interface
score: 2.4762584, FEBS Letters, 1999, Martin, Carole; Hartley, Robert; Mauguen, Yves

New insights into intracellular lipid binding proteins: The role of buried water.
score: 2.4760769, Protein science : a publication of the Protein Society, 2002, Lücke, Christian et. al.

NMR solution structure of the angiostatic peptide anginex
score: 2.4757456, BBA - Proteins and Proteomics, 2007, Arroyo, Monica M.; Mayo, Kevin H.

Mutational Analysis of the Complement Receptor Type 2 (CR2/CD21)–C3d Interaction Reveals a Putative Charged SCR1 Binding Site for C3d
score: 2.4755949, Journal of Molecular Biology, 2005, Hannan, Jonathan P. et. al.

Electron Crystal Structure of an RNA Polymerase II Transcription Elongation Complex
score: 2.4750795, Cell, 1999, Poglitsch, Claudia L et. al.

Elucidating the medium-resolution structure of ribosomal particles: an interplay between electron cryo-microscopy and X-ray crystallography
score: 2.474845, Structure, 1999, Harms, Jörg et. al.

Crystallization and a preliminary X-ray crystallographic study of α-amylase from Bacillus licheniformis
score: 2.4745406, Archives of Biochemistry and Biophysics, 1991, Lee, Suk Yeong; Kim, Sangsoo; Sweet, Robert M.; Suh, Se Won

Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors α/γ dual agonists
score: 2.4743787, Bioorganic & Medicinal Chemistry, 2012, Fracchiolla, Giuseppe et. al.

Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops
score: 2.4738259, Nature Structural & Molecular Biology, 2011, Gupta, Shikha; Gellert, Martin; Yang, Wei

Structure-based 3D-QSAR models and dynamics analysis of novel N-benzyl pyridinone as p38α MAP kinase inhibitors for anticytokine activity
score: 2.4728196, Journal of Molecular Graphics and Modelling, 2012, Ul-Haq, Zaheer et. al.

Structure-based 3D-QSAR models and dynamics analysis of novel N-benzyl pyridinone as p38α MAP kinase inhibitors for anticytokine activity
score: 2.4728196, Journal of Molecular Graphics and Modelling, 2012, Ul-Haq, Zaheer et. al.

RNase H2 roles in genome integrity revealed by unlinking its activities
score: 2.4726376, Nucleic Acids Research, 2013, Chon, Hyongi et. al.

Insights into Molecular Plasticity of Choline Binding Proteins (Pneumococcal Surface Proteins) by SAXS
score: 2.4718699, Journal of Molecular Biology, 2007, Buey, Rubén M. et. al.

Structures of dNTP Intermediate States during DNA Polymerase Active Site Assembly
score: 2.4716681, Structure, 2012, Freudenthal, Bret D.; Beard, William A.; Wilson, Samuel H.

Structures of dNTP Intermediate States during DNA Polymerase Active Site Assembly
score: 2.4716681, Structure, 2012, Freudenthal, Bret D.; Beard, William A.; Wilson, Samuel H.

Structural Flexibility of the N-terminal β-Barrel Domain of 15-Lipoxygenase-1 Probed by Small Angle X-ray Scattering. Functional Consequences for Activity Regulation and Membrane Binding
score: 2.471644, Journal of Molecular Biology, 2004, Hammel, Michal et. al.

Evidence for an ABC-Type Riboflavin Transporter System in Pathogenic Spirochetes
score: 2.4711767, mBio, 2013, Deka, Ranjit K. et. al.

Small Molecule Bromodomain Inhibitors-1:Extending the Druggable Genome
score: 2.4710718, Progress in Medicinal Chemistry, 2012, Chung, Chun-wa

The active form of the norovirus RNA-dependent RNA polymerase is a homodimer with cooperative activity.
score: 2.4708776, The Journal of general virology, 2009, Högbom, Martin et. al.

Structural and mechanistic comparison of prokaryotic and eukaryotic phosphoinositide-specific phospholipases C 1 1 Edited by K. Nagai
score: 2.4700588, Journal of Molecular Biology, 1998, Heinz, Dirk W.; Essen, Lars-Oliver; Williams, Roger L.

Binding of aldolase and glyceraldehyde-3-phosphate dehydrogenase to the cytoplasmic tails of Plasmodium falciparum merozoite duffy binding-like and reticulocyte homology ligands.
score: 2.4699805, mBio, 2012, Pal-Bhowmick, Ipsita et. al.

Structural studies on 26RFa, a novel human RFamide-related peptide with orexigenic activity
score: 2.4699731, Peptides, 2005, Thuau, Romain et. al.

Localization of ASV Integrase-DNA Contacts by Site-Directed Crosslinking and their Structural Analysis
score: 2.4682135, PLoS ONE, 2011, Peletskaya, Elena et. al.

Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization.
score: 2.4680813, Proceedings of the National Academy of Sciences of the United States of America, 1997, Garcia, K C et. al.

The Structure of a Two-Disulfide Intermediate Assists in Elucidating the Oxidative Folding Pathway of a Cyclic Cystine Knot Protein
score: 2.4680668, Structure, 2008, Cemazar, Maša et. al.

Automated Analysis of Vapor Diffusion Crystallization Drops with an X-Ray Beam
score: 2.4679008, Structure, 2004, Jacquamet, Lilian et. al.

Crystal structure of human Intersectin-2L C2 domain
score: 2.4677631, Biochemical and Biophysical Research Communications, 2013, Zhang, Wei et. al.

An Efficient Strategy for the Determination of the Three-Dimensional Architecture of Ribonucleoprotein Complexes by the Combination of a Few Easily Accessible NMR and Biochemical Data: Intermolecular Recognition in a U4 Spliceosomal Complex
score: 2.4656487, Journal of Molecular Biology, 2009, Li, Ping; Kirkpatrick, John; Carlomagno, Teresa

Solution Structure of the SL1 RNA of the M1 Double-Stranded RNA Virus of Saccharomyces cerevisiae
score: 2.465028, Biophysical Journal, 2001, Yoo, Jun-Seok et. al.

Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides.
score: 2.4642566, Proceedings of the National Academy of Sciences of the United States of America, 1996, Jardetzky, T S et. al.

Sampling protein motion and solvent effect during ligand binding.
score: 2.4637763, Proceedings of the National Academy of Sciences of the United States of America, 2012, Limongelli, Vittorio et. al.

Selective boron-Containing thrombin inhibitors—X-ray analysis reveals surprising binding mode
score: 2.4626784, Bioorganic & Medicinal Chemistry, 2000, von Matt, Anette et. al.

Local and global structure of the monomeric subunit of the potassium channel KcsA probed by NMR
score: 2.4625291, BBA - Biomembranes, 2007, Chill, Jordan H.; Louis, John M.; Delaglio, Frank; Bax, Ad

Retrovirus envelope protein complex structure in situ studied by cryo-electron tomography.
score: 2.4615195, Proceedings of the National Academy of Sciences of the United States of America, 2005, Förster, Friedrich et. al.

Intra- and Intermonomer Interactions Are Required to Synergistically Facilitate ATP Hydrolysis in Hsp90 * S⃞ ♦
score: 2.4612942, The Journal of Biological Chemistry, 2008, Cunningham, Christian N. et. al.

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site.
score: 2.4598622, Nature structural & molecular biology, 2010, Li, Qing et. al.

Membrane Proteins Modulate the Bilayer Curvature in the Bacterial Virus Bam35
score: 2.4594465, Structure, 2005, Laurinmäki, Pasi Antero et. al.

Hsc70-interacting HPD Loop of the J Domain of Polyomavirus T Antigens Fluctuates in ps to ns and μs to ms
score: 2.4591631, Journal of Molecular Biology, 2002, Berjanskii, Mark V; Riley, Michael I; Van Doren, Steven R

An Interplay between Protein Disorder and Structure Confers the Ca 2+ Regulation of Striated Muscle
score: 2.4582136, Journal of Molecular Biology, 2006, Hoffman, Ryan M.B. et. al.

Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9).
score: 2.4567245, Nucleic acids research, 2013, Fu, Qinqin; Yuan, Y Adam

Coagulation factors and their inhibitors
score: 2.4566396, Current Opinion in Structural Biology, 1994, Stubbs, Milton T.; Bode, Wolfram

Solution structure of DNA/RNA hybrid duplex with C8-propynyl 2′-deoxyadenosine modifications: Implication of RNase H and DNA/RNA duplex interaction
score: 2.4565114, BBA - Gene Structure and Expression, 2007, Lee, Hunjoong et. al.

Hydrogen atoms in proteins: positions and dynamics.
score: 2.456453, Proceedings of the National Academy of Sciences of the United States of America, 2003, Engler, Niklas et. al.

The many types of interhelical ionic interactions in coiled coils – An overview
score: 2.4562395, Journal of Structural Biology, 2010, Meier, Markus; Stetefeld, Jörg; Burkhard, Peter

Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A resolution.
score: 2.4562246, Proceedings of the National Academy of Sciences of the United States of America, 1991, Ke, H M; Zydowsky, L D; Liu, J; Walsh, C T

The Lac repressor: a second generation of structural and functional studies
score: 2.4557032, Current Opinion in Structural Biology, 2001, Bell, Charles E; Lewis, Mitchell

Structure of an isolated gramicidin A double helical species by high-resolution nuclear magnetic resonance
score: 2.4556427, Journal of Molecular Biology, 1992, Pascal, S.M.; Cross, T.A.

Bridging the Gap between Structural Models of Nicotinic Receptor Superfamily Ion Channels and Their Corresponding Functional States
score: 2.4556032, Journal of Molecular Biology, 2010, Gonzalez-Gutierrez, Giovanni; Grosman, Claudio

Crystallization and preliminary X-ray diffraction analysis of human adenovirus
score: 2.4542993, Virology, 2010, Reddy, V.S. et. al.

Insight into the activity of SARS main protease: Molecular dynamics study of dimeric and monomeric form of enzyme.
score: 2.4539381, Proteins, 2007, Zheng, Kewen et. al.

Structure of the rhesus monkey TRIM5α PRYSPRY domain, the HIV capsid recognition module.
score: 2.4536987, Proceedings of the National Academy of Sciences of the United States of America, 2012, Biris, Nikolaos et. al.

Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system
score: 2.4532136, Protein Expression and Purification, 2007, Bashiri, Ghader et. al.

The DINGO dataset: a comprehensive set of data for the SAMPL challenge
score: 2.452615, Journal of Computer-Aided Molecular Design, 2011, Newman, Janet et. al.

Crystallization and preliminary X-ray diffraction analysis of monoprenylated Rab7 GTPase in complex with Rab escort protein 1
score: 2.4518554, Journal of Structural Biology, 2003, Rak, Alexey et. al.

The structure of iron–sulfur proteins
score: 2.4514947, Progress in Biophysics and Molecular Biology, 1998, Sticht, Heinrich; Rösch, Paul

Solution structure of a peptide derived from the oncogenic protein β-Catenin in its phosphorylated and nonphosphorylated states
score: 2.4497567, Peptides, 2005, Megy, Simon et. al.

Integrin Conformational Regulation: Uncoupling Extension/Tail Separation from Changes in the Head Region by a Multiresolution Approach
score: 2.4495785, Structure, 2008, Rocco, Mattia et. al.

Preparation and crystallization of a human immunodeficiency virus p24-Fab complex.
score: 2.449234, Proceedings of the National Academy of Sciences of the United States of America, 1990, Prongay, A J et. al.

Chapter 2 The Structure and Function of Insulin
score: 2.4489285, Vitamins and Hormones, 2009, Weiss, Michael A.

Synchrotron radiation applications to macromolecular crystallography
score: 2.4485365, Current Opinion in Structural Biology, 1997, Moffat, Keith; Ren, Zhong

Purification, Analysis, and Crystal Structure of Integrins
score: 2.4474034, Methods in Enzymology, 2007, Xiong, Jian‐Ping; Goodman, Simon L.; Amin Arnaout, M.

Generation of longer emission wavelength red fluorescent proteins using computationally designed libraries.
score: 2.447236, Proceedings of the National Academy of Sciences of the United States of America, 2010, Chica, Roberto A et. al.

Identification of a protein-binding surface by differential amide hydrogen-exchange measurements
score: 2.4472014, Journal of Molecular Biology, 1992, Werner, Milton H.; Wemmer, David E.

Expression Improvement and Mechanistic Study of the Retro-Diels-Alderase Catalytic Antibody 10F11 by Site-directed Mutagenesis
score: 2.447188, Journal of Molecular Biology, 2004, Zheng, Lei et. al.

Solution structures and model membrane interactions of lactoferrampin, an antimicrobial peptide derived from bovine lactoferrin
score: 2.4471298, BBA - Biomembranes, 2007, Haney, Evan F.; Lau, Fanny; Vogel, Hans J.

Structure and functions of the GNAT superfamily of acetyltransferases
score: 2.4465239, Archives of Biochemistry and Biophysics, 2005, Vetting, Matthew W. et. al.

Molecular basis for a protein-mediated DNA bridging mechanism that functions in condensation of the E. coli chromosome
score: 2.4459561, Molecular Cell, 2012, Dupaigne, Pauline et. al.

Lipopolysaccharide bound structures of the active fragments of fowlicidin-1, a cathelicidin family of antimicrobial and antiendotoxic peptide from chicken, determined by transferred nuclear Overhauser effect spectroscopy.
score: 2.4456707, Biopolymers, 2009, Bhunia, Anirban; Mohanram, Harini; Bhattacharjya, Surajit

Structural propensities in the heme binding region of apocytochrome b5. I. Free peptides.
score: 2.4449606, Biopolymers, 2008, Davis, Ronald B; Lecomte, Juliette T J

Conformational changes in ammonia-channeling glutamine amidotransferases
score: 2.4445667, Current Opinion in Structural Biology, 2007, Mouilleron, Stéphane; Golinelli-Pimpaneau, Béatrice

The Structure of an Archaeal Viral Integrase Reveals an Evolutionarily Conserved Catalytic Core yet Supports a Mechanism of DNA Cleavage in trans.
score: 2.4438259, Journal of virology, 2012, Eilers, Brian J; Young, Mark J; Lawrence, C Martin

Enzymatic stability, solution structure, and antiproliferative effect on prostate cancer cells of leuprolide and new gonadotropin-releasing hormone peptide analogs.
score: 2.4433251, Biopolymers, 2011, Pappa, Eleni V et. al.

Structural and functional properties of low molecular weight endo-1,4-β -xylanases
score: 2.4432148, Journal of Biotechnology, 1997, Törrönen, Anneli; Rouvinen, Juha

Crystal structure of the Candida albicans Kar3 kinesin motor domain fused to maltose-binding protein
score: 2.4427836, Biochemical and Biophysical Research Communications, 2012, Delorme, Caroline; Joshi, Monika; Allingham, John S.

Synthesis and glycosidase inhibitory activity of 5-thioglucopyranosylamines. Molecular modeling of complexes with glucoamylase
score: 2.4417998, Carbohydrate Research, 1999, Randell, Karla D. et. al.

Determining the 3D structure of human ASC2 protein involved in apoptosis and inflammation
score: 2.4413727, Biochemical and Biophysical Research Communications, 2006, Espejo, Fabiola; Patarroyo, Manuel E.

X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis.
score: 2.4411986, Proceedings of the National Academy of Sciences of the United States of America, 1992, Privé, G G et. al.

Neutron crystallography: opportunities, challenges, and limitations
score: 2.437329, Current Opinion in Structural Biology, 2008, Blakeley, Matthew P et. al.

Structure and function of Polo-like kinases.
score: 2.437022, Oncogene, 2005, Lowery, Drew M; Lim, Daniel; Yaffe, Michael B

Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′ λ 6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2 H-pyridazin-3-ones. Part 2: Variation of the 2- and 6-pyridazinone substituents
score: 2.4352539, Bioorganic & Medicinal Chemistry Letters, 2008, Zhou, Yuefen et. al.

Purification and Preliminary Crystallographic Analysis of a New Lys49-PLA2 from B. Jararacussu
score: 2.4350788, International Journal of Molecular Sciences, 2008, dos Santos, Marcelo L. et. al.

Molecular Control of a Bimodal Distribution of Quinone-Analogue Inhibitor Binding Sites in the Cytochrome b 6 f Complex
score: 2.4346741, Journal of Molecular Biology, 2004, Yan, Jiusheng; Cramer, William A.

Ligand-induced Conformational Changes via Flexible Linkers in the Amino-terminal region of the Inositol 1,4,5-Trisphosphate Receptor
score: 2.4338549, Journal of Molecular Biology, 2007, Chan, Jenny et. al.

Solution NMR studies of amphibian antimicrobial peptides: Linking structure to function?
score: 2.4336907, BBA - Biomembranes, 2009, Haney, Evan F. et. al.

Unfolding of the C-Terminal Domain of the J-Protein Zuo1 Releases Autoinhibition and Activates Pdr1-Dependent Transcription
score: 2.4335048, Journal of Molecular Biology, 2013, Ducett, Jeanette K. et. al.

Arginine 104 Is a Key Catalytic Residue in Leukotriene C 4 Synthase *
score: 2.4326949, The Journal of Biological Chemistry, 2010, Rinaldo-Matthis, Agnes et. al.

Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy.
score: 2.4323877, Proceedings of the National Academy of Sciences of the United States of America, 2011, Boura, Evzen et. al.

Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants.
score: 2.4321549, The EMBO journal, 1997, Hopfner, K P et. al.

A comparative study of fragment screening methods on the p38α kinase: new methods, new insights
score: 2.4318786, Journal of Computer-Aided Molecular Design, 2011, Pollack, Scott J. et. al.

Structure of an engineered porcine phospholipase A 2 with enhanced activity at 2·1 Å resolution
score: 2.4306004, Journal of Molecular Biology, 1990, Thunnissen, Marjolein M.G.M. et. al.

Structural and Functional Studies of Nup107/Nup133 Interaction and Its Implications for the Architecture of the Nuclear Pore Complex
score: 2.4305768, Molecular Cell, 2008, Boehmer, Thomas et. al.

Activation Mechanism of the Nuclear Chaperone Nucleoplasmin: Role of the Core Domain
score: 2.4300273, Journal of Molecular Biology, 2003, Bañuelos, Sonia et. al.

Structural Characterization of the RyR1–FKBP12 Interaction
score: 2.4293903, Journal of Molecular Biology, 2006, Samsó, Montserrat; Shen, Xiaohua; Allen, Paul D.

Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids.
score: 2.428847, Proceedings of the National Academy of Sciences of the United States of America, 2011, Garcia-Alles, Luis F et. al.

Bardet-Biedl Syndrome-associated Small GTPase ARL6 (BBS3) Functions at or near the Ciliary Gate and Modulates Wnt Signaling *
score: 2.4283681, The Journal of Biological Chemistry, 2010, Wiens, Cheryl J. et. al.

Electron cryomicroscopy structure of N-ethyl maleimide sensitive factor at 11 A resolution.
score: 2.4283575, The EMBO journal, 2003, Furst, Johannes et. al.

Structure of the YSPTSPS repeat containing two SPXX motifs in the CTD of RNA polymerase II: NMR studies of cyclic model peptides reveal that the SPTS turn is more stable than SPSY in water
score: 2.4278576, Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology, 2001, Kumaki, Yasuhiro et. al.

Structural Analysis and Dynamics of Retinal Chromophore in Dark and Meta I States of Rhodopsin from 2H NMR of Aligned Membranes
score: 2.4277148, Journal of Molecular Biology, 2007, Struts, Andrey V. et. al.

The Role of a Hydrogen Bonding Network in the Transmembrane β-Barrel OMPLA
score: 2.4276871, Journal of Molecular Biology, 2007, Stanley, Ann Marie; Fleming, Karen G.

Four Human Thiopurine S-Methyltransferase Alleles Severely Affect Protein Structure and Dynamics
score: 2.4276713, Journal of Molecular Biology, 2008, Rutherford, Karen; Daggett, Valerie

Does the solid-state structure of endothelin-1 provide insights concerning the solution-state conformational equilibrium?
score: 2.4272847, FEBS Letters, 1994, Lee, Gregory M. et. al.

The symmetry of Escherichia coli cpn60 (GroEL) determined by X-ray crystallography
score: 2.4270435, Journal of Molecular Biology, 1994, Anders Svensson, L. et. al.

Conversion between Three Conformational States of Integrin I Domains with a C-Terminal Pull Spring Studied with Molecular Dynamics
score: 2.4269778, Structure, 2004, Jin, Moonsoo; Andricioaei, Ioan; Springer, Timothy A.

Proline-dependent oligomerization with arm exchange
score: 2.4253724, Structure, 1997, Bergdoll, Marc et. al.

STAP Refinement of the NMR database: a database of 2405 refined solution NMR structures
score: 2.4253469, Nucleic Acids Research, 2011, Yang, Joshua SungWoo et. al.

Comparative modeling of the three-dimensional structures of family 3 glycoside hydrolases.
score: 2.4249713, Proteins, 2000, Harvey, A J et. al.

The Structure and Function of Nodavirus Particles: A Paradigm for Understanding Chemical Biology
score: 2.4242795, Advances in Virus Research, 1998, Schneemann, Anette; Reddy, Vijay; Johnson, John E.

Simultaneous structure and dynamics of a membrane protein using REDCRAFT: Membrane-bound form of Pf1 coat protein
score: 2.4240378, Journal of Magnetic Resonance, 2010, Shealy, Paul et. al.

Hyper-thermostability of CutA1 protein, with a denaturation temperature of nearly 150 °C
score: 2.4240093, FEBS Letters, 2006, Tanaka, Tomoyuki et. al.

1H NMR assignments of apo calcyclin and comparative structural analysis with calbindin D9k and S100 beta.
score: 2.4232306, Protein science : a publication of the Protein Society, 1996, Potts, B C; Carlström, G; Okazaki, K; Hidaka, H; Chazin, W J

Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes
score: 2.4217964, Current Opinion in Structural Biology, 1998, Brautigam, Chad A; Steitz, Thomas A

Design and synthesis of bisubstrate inhibitors of type 1 17β-hydroxysteroid dehydrogenase: Overview and perspectives
score: 2.4211053, European Journal of Medicinal Chemistry, 2008, Fournier, D.; Poirier, D.; Mazumdar, M.; Lin, S.-X.

The structural plasticity of SCA7 domains defines their differential nucleosome-binding properties.
score: 2.4207234, EMBO reports, 2010, Bonnet, Jacques et. al.

Themes in RNA-protein recognition
score: 2.4207162, Journal of Molecular Biology, 1999, Draper, David E

Phosphoglucomutase is absent in Trypanosoma brucei and redundantly substituted by phosphomannomutase and phospho- N -acetylglucosamine mutase
score: 2.4207098, Molecular Microbiology, 2012, Bandini, Giulia et. al.

Solution 1H NMR study of the active site structure for the double mutant H64Q/V68F cyanide complex from mouse neuroglobin
score: 2.4198315, Biophysical Chemistry, 2008, Yin, Guowei et. al.

Novel triazolopyridylbenzamides as potent and selective p38α inhibitors
score: 2.4193901, Bioorganic & Medicinal Chemistry Letters, 2012, Aiguadé, Josep et. al.

Novel triazolopyridylbenzamides as potent and selective p38α inhibitors
score: 2.4193901, Bioorganic & Medicinal Chemistry Letters, 2012, Aiguadé, Josep et. al.

Novel triazolopyridylbenzamides as potent and selective p38α inhibitors
score: 2.4193901, Bioorganic & Medicinal Chemistry Letters, 2012, Aiguadé, Josep et. al.

The Effects of Mutations on Motions of Side-chains in Protein L Studied by 2H NMR Dynamics and Scalar Couplings
score: 2.418258, Journal of Molecular Biology, 2003, Millet, Oscar et. al.

Structural features of isolated M2 helices of nicotinic receptors. Simulated annealing via molecular dynamics studies
score: 2.4180833, Biophysical Chemistry, 1995, Sankararamakrishnan, R.; Sansom, M.S.P.

Assays for the Determination of Structure and Dynamics of the Interaction of the Chromodomain with Histone Peptides
score: 2.4175994, Methods in Enzymology, 2003, Jacobs, Steven A. et. al.

Structural Analysis of IL-10 and Type I Interferon Family Members and their Complexes with Receptor
score: 2.4175308, Advances in Protein Chemistry, 2004, Walter, Mark R.

An Arabidopsis SBP-domain fragment with a disrupted C-terminal zinc-binding site retains its tertiary structure
score: 2.4174518, FEBS Letters, 2006, Yamasaki, Kazuhiko et. al.

A novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI), GRL-98065, is potent against multiple-PI-resistant human immunodeficiency virus in vitro.
score: 2.4173163, Antimicrobial agents and chemotherapy, 2007, Amano, Masayuki et. al.

Structure of adeno-associated virus serotype 5.
score: 2.4147742, Journal of virology, 2004, Walters, Robert W et. al.

Structure and electron transfer mechanism of pyruvate:ferredoxin oxidoreductase
score: 2.413305, Current Opinion in Structural Biology, 1999, Charon, Marie-Helene et. al.

Na + Site in Blood Coagulation Factor IXa: Effect on Catalysis and Factor VIIIa Binding
score: 2.4125269, Journal of Molecular Biology, 2005, Schmidt, Amy E. et. al.

Determining local conformational variations in DNA
score: 2.4113183, Journal of Molecular Biology, 1990, Metzler, William J. et. al.

Differential Epitope Positioning within the Germline Antibody Paratope Enhances Promiscuity in the Primary Immune Response
score: 2.4100446, Immunity, 2006, Sethi, Dhruv K. et. al.

Crystallization of the membrane protein hVDAC1 produced in cell-free system
score: 2.4096334, BBA - Biomembranes, 2010, Deniaud, A. et. al.

A Coiled-Coil Structure of the αIIbβ3 Integrin Transmembrane and Cytoplasmic Domains in Its Resting State
score: 2.4095059, Structure, 2005, Gottschalk, Kay-Eberhard

Nuclear Magnetic Resonance Spectroscopy in the Study of Hemoglobin Cooperativity
score: 2.4090921, Methods in Enzymology, 2004, Barrick, Doug et. al.

Relationships between protein structure and dynamics from a database of NMR-derived backbone order parameters 1 1 Edited by P. E. Wright
score: 2.4085165, Journal of Molecular Biology, 2000, Goodman, Joshua L; Pagel, Mark D; Stone, Martin J

Crystallisation of RNA-protein complexes II. The application of protein engineering for crystallisation of the U1A protein-RNA complex
score: 2.4077189, Journal of Molecular Biology, 1995, Oubridge, Chris et. al.

Portal-large terminase interactions of the bacteriophage T4 DNA packaging machine implicate a molecular lever mechanism for coupling ATPase to DNA translocation.
score: 2.4074377, Journal of virology, 2012, Hegde, Shylaja et. al.

Insights into Transcription Initiation and Termination from the Electron Microscopy Structure of Yeast RNA Polymerase III
score: 2.4071923, Molecular Cell, 2007, Fernández-Tornero, Carlos et. al.

The structure and function of drug pumps: an update
score: 2.4063401, Trends in Microbiology, 2003, McKeegan, Kenneth S et. al.

RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.
score: 2.4062866, Cancer research, 2012, Patel, Ronil A et. al.

Roles of the Ser146, Tyr159, and Lys163 residues in the catalytic action of 7alpha-hydroxysteroid dehydrogenase from Escherichia coli.
score: 2.406049, Journal of biochemistry, 1998, Tanabe, T et. al.

Analysis of the Open and Closed Conformations of the β Subunits in Thermophilic F 1-ATPase by Solution NMR
score: 2.4055501, Journal of Molecular Biology, 2010, Kobayashi, Masumi et. al.

HIV-1 encoded virus protein U (Vpu) solution structure of the 41–62 hydrophilic region containing the phosphorylated sites Ser 52 and Ser 56
score: 2.4047353, International Journal of Biological Macromolecules, 2002, Coadou, Gaël et. al.

Crystallisation and crystallographic investigations of cod alcohol dehydrogenase class I and class III enzymes
score: 2.4040614, FEBS Letters, 1994, Ramaswamy, S. et. al.

Structure of Cowpea mottle virus: a consensus in the genus Carmovirus
score: 2.4040337, Virology, 2004, Ke, Jiyuan et. al.

Structural characterization of human Uch37.
score: 2.4040015, Proteins, 2011, Burgie, Sethe E et. al.

The crystal structure of the CRISPR-associated protein Csn2 from Streptococcus agalactiae
score: 2.4027624, Journal of Structural Biology, 2012, Ellinger, Philipp et. al.

The crystal structure of the CRISPR-associated protein Csn2 from Streptococcus agalactiae
score: 2.4027624, Journal of Structural Biology, 2012, Ellinger, Philipp et. al.

Observation of the light-triggered binding of pyrone to chymotrypsin by Laue x-ray crystallography.
score: 2.4026377, Proceedings of the National Academy of Sciences of the United States of America, 1991, Stoddard, B L et. al.

Insights into the Regulatory Landscape of the Lysine Riboswitch
score: 2.4004824, Journal of Molecular Biology, 2012, Garst, Andrew D.; Porter, Ely B.; Batey, Robert T.

Substrate binding and carboxylation by dethiobiotin synthetase — a kinetic and X-ray study
score: 2.4000984, Structure, 1995, Alexeev, Dmitriy et. al.

NMR Studies in Dodecylphosphocholine of a Fragment Containing the Seventh Transmembrane Helix of a G-Protein-Coupled Receptor from Saccharomyces cerevisiae
score: 2.3990294, Biophysical Journal, 2007, Neumoin, Alexey et. al.

Characterizing a Partially Folded Intermediate of the Villin Headpiece Domain Under Non-denaturing Conditions: Contribution of His41 to the pH-dependent Stability of the N-terminal Subdomain
score: 2.3987685, Journal of Molecular Biology, 2006, Grey, Michael J. et. al.

Synthetic human prion protein octapeptide repeat binds to the proteinase K active site
score: 2.3984695, Biochemical and Biophysical Research Communications, 2004, Georgieva, Dessislava et. al.

HLA-B27 Subtypes Differentially Associated with Disease Exhibit Conformational Differences in Solution
score: 2.3983743, Journal of Molecular Biology, 2008, Fabian, Heinz et. al.

Template strand scrunching during DNA gap repair synthesis by human polymerase lambda.
score: 2.3977728, Nature structural & molecular biology, 2009, Garcia-Diaz, Miguel et. al.

Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels.
score: 2.3972153, Cell research, 2011, Ma, Gang et. al.

The crystal structure of the CRISPR-associated protein Csn2 from Streptococcus agalactiae
score: 2.3964768, Journal of Structural Biology, 2012, Ellinger, Philipp et. al.

X-ray structural and simulation analysis of a protein mutant: the value of a combined approach.
score: 2.3959057, Proteins, 2004, Mattos, Carla et. al.

Structures of amyloid fibrils formed by the prion protein derived peptides PrP(244–249) and PrP(245–250)
score: 2.3953232, Journal of Structural Biology, 2012, Yau, Jason; Sharpe, Simon

Characterization of the acetate binding pocket in the Methanosarcina thermophila acetate kinase.
score: 2.3951482, Journal of bacteriology, 2005, Ingram-Smith, Cheryl et. al.

The catalytic subunit of cAMP-dependent protein kinase: prototype for an extended network of communication
score: 2.394926, Progress in Biophysics and Molecular Biology, 1999, Smith, Christopher M. et. al.

Protein structure determination using a database of interatomic distance probabilities.
score: 2.3944762, Protein science : a publication of the Protein Society, 1999, Wall, M E; Subramaniam, S; Phillips, G N

Novel modifications in the series of O-(2-phthalimidoethyl)- N-substituted thiocarbamates and their ring-opened congeners as non-nucleoside HIV-1 reverse transcriptase inhibitors
score: 2.3943268, European Journal of Medicinal Chemistry, 2009, Spallarossa, Andrea et. al.

Protein engineering
score: 2.393557, Current Opinion in Biotechnology, 1996,

Localization and quaternary structure of the PKA RIβ holoenzyme.
score: 2.3919412, Proceedings of the National Academy of Sciences of the United States of America, 2012, Ilouz, Ronit et. al.

Structure of the Blm10–20 S Proteasome Complex by Cryo-electron Microscopy. Insights into the Mechanism of Activation of Mature Yeast Proteasomes
score: 2.3912984, Journal of Molecular Biology, 2006, Iwanczyk, Jack et. al.

Extending the Folding Nucleus of Ubiquitin with an Independently Folding β-Hairpin Finger: Hurdles to Rapid Folding Arising from the Stabilisation of Local Interactions
score: 2.3884409, Journal of Molecular Biology, 2005, Bofill, Roger et. al.

Design, synthesis and biological evaluation of potent NAD+-dependent DNA ligase inhibitors as potential antibacterial agents. Part 2: 4-Amino-pyrido[2,3-d]pyrimidin-5(8H)-ones
score: 2.387618, Bioorganic & Medicinal Chemistry Letters, 2012, Wang, Tiansheng et. al.

Localization of ammonium ions in the minor groove of DNA duplexes in solution and the origin of DNA A-tract bending 1 1 Edited by I. Tinoco
score: 2.3874191, Journal of Molecular Biology, 1999, Hud, Nicholas V; Sklenář, Vladimir; Feigon, Juli

NMR solution structure of NBD94(483-502) of the nucleotide-binding domain of the Plasmodium yoelii reticulocyte-binding protein Py235.
score: 2.3872783, FEMS microbiology letters, 2011, Basak, Sandip et. al.

NMR structural studies of human cystatin C dimers and monomers 1 1 Edited by P. E. Wright
score: 2.3869461, Journal of Molecular Biology, 1997, Ekiel, I. et. al.

The nicotinamide dinucleotide binding motif: a comparison of nucleotide binding proteins.
score: 2.3866976, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1996, Bellamacina, C R

Neutron diffraction study of carbonmonoxymyoglobin
score: 2.3864238, Journal of Molecular Biology, 1991, Cheng, Xiaodong; Schoenborn, Benno P.

Protein fold determined by paramagnetic magic-angle spinning solid-state NMR spectroscopy
score: 2.3864021, Nature chemistry, 2012, Sengupta, Ishita et. al.

Purification, crystallization and X-ray diffraction analyses of the T. elongatus PSII core dimer with strontium replacing calcium in the oxygen-evolving complex
score: 2.3858395, BBA - Bioenergetics, 2007, Kargul, Joanna et. al.

Methyl groups as probes of structure and dynamics in NMR studies of high-molecular-weight proteins.
score: 2.385678, Chembiochem : a European journal of chemical biology, 2005, Tugarinov, Vitali; Kay, Lewis E

The Principal Motions Involved in the Coupling Mechanism of the Recovery Stroke of the Myosin Motor
score: 2.3846175, Journal of Molecular Biology, 2007, Mesentean, Sidonia et. al.

Synthetic Peptides as Structural Maquettes of Angiotensin-I Converting Enzyme Catalytic Sites
score: 2.3844824, Bioinorganic Chemistry and Applications, 2010, Spyranti, Zinovia et. al.

DNA-induced α-helix capping in conserved linker sequences is a determinant of binding affinity in Cys 2-His 2 zinc fingers 1 1 Edited by F. E. Cohen
score: 2.3831822, Journal of Molecular Biology, 2000, Laity, John H; Dyson, H.Jane; Wright, Peter E

Water mediated Dickerson-Drew-type crystal of DNA dodecamer containing 2′-deoxy-5-formyluridine
score: 2.3828032, Biophysical Chemistry, 2002, Tsunoda, Masaru et. al.

Structure and function of the N-linked glycans of HBP/CAP37/azurocidin: crystal structure determination and biological characterization of nonglycosylated HBP.
score: 2.381496, Protein science : a publication of the Protein Society, 1999, Iversen, L F et. al.

Protein–Protein and Protein–DNA Interactions of σ 70 Region 4 Involved in Transcription Activation by λcI
score: 2.3814859, Journal of Molecular Biology, 2002, Nickels, Bryce E. et. al.

New vectors for co-expression of proteins: Structure of Bacillus subtilis ScoAB obtained by high-throughput protocols
score: 2.3809825, Protein Expression and Purification, 2007, Stols, Lucy et. al.

Interaction of the Dengue Virus Fusion Peptide with Membranes Assessed by NMR: The Essential Role of the Envelope Protein Trp101 for Membrane Fusion
score: 2.3799392, Journal of Molecular Biology, 2009, Melo, Manuel Nuno et. al.

The development and application of new crystallization method for tobacco mosaic virus coat protein
score: 2.3792424, Virology Journal, 2012, Li, Xiangyang et. al.

Chapter 2 Structural Enzymology of Polyketide Synthases
score: 2.3788716, Methods in Enzymology, 2009, (Sheryl) Tsai, Shiou‐Chuan; Ames, Brian Douglas

Chapter 2 Structural Enzymology of Polyketide Synthases
score: 2.3788716, Methods in Enzymology, 2009, (Sheryl) Tsai, Shiou‐Chuan; Ames, Brian Douglas

The HU protein from Thermotoga maritima: recombinant expression, purification and physicochemical characterization of an extremely hyperthermophilic DNA-binding protein 1 1 Edited by T. Richmond
score: 2.3774069, Journal of Molecular Biology, 1999, Esser, Dirk; Rudolph, Rainer; Jaenicke, Rainer; Böhm, Gerald

A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps.
score: 2.3773634, Proceedings of the National Academy of Sciences of the United States of America, 2007, Lobedanz, Sune et. al.

New trends in macromolecular X-ray crystallography
score: 2.3772284, Current Opinion in Chemical Biology, 1997, Wery, Jean-Pierre; Schevitz, Richard W

Tissue inhibitor of metalloproteinases-1 undergoes microsecond to millisecond motions at sites of matrix metalloproteinase-induced fit 1 1 Edited by P. E. Wright
score: 2.3768043, Journal of Molecular Biology, 2000, Gao, Guanghua et. al.

Sequence context effect on the structure of nitrous acid induced DNA interstrand cross-links.
score: 2.3764315, Nucleic acids research, 2004, Edfeldt, N B Fredrik et. al.

Probing protein structure by solvent perturbation of NMR spectra: the surface accessibility of bovine pancreatic trypsin inhibitor
score: 2.3761461, Biophysical Journal, 1997, Molinari, H. et. al.

Phasing Macromolecular Structures with UV-Induced Structural Changes
score: 2.3759479, Structure, 2006, Nanao, Max H.; Ravelli, Raimond B.G.

The structure of porin from Paracoccus denitrificans at 3.1 Å resolution
score: 2.3753213, FEBS Letters, 1997, Hirsch, A. et. al.

The structure of porin from Paracoccus denitrificans at 3.1 Å resolution
score: 2.3753213, FEBS Letters, 1997, Hirsch, A. et. al.

Crystal Structure of Δ(185–243)ApoA-I Suggests a Mechanistic Framework for the Protein Adaptation to the Changing Lipid Load in Good Cholesterol: From Flatland to Sphereland via Double Belt, Belt Buckle, Double Hairpin and Trefoil/Tetrafoil
score: 2.3746344, Journal of Molecular Biology, 2013, Gursky, Olga

Adjacent zinc-finger motifs in multiple zinc-finger peptides from SWI5 form structurally independent, flexibly linked domains
score: 2.374185, Journal of Molecular Biology, 1992, Nakaseko, Yukinobu et. al.

Nanometer Propagation of Millisecond Motions in V-Type Allostery
score: 2.3726207, Structure, 2010, Lipchock, James M.; Loria, J. Patrick

Restricted domain mobility in the Candida albicans Ess1 prolyl isomerase
score: 2.3723758, BBA - Proteins and Proteomics, 2010, McNaughton, Lynn et. al.

Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening
score: 2.370728, Bioorganic & Medicinal Chemistry Letters, 2009, Neres, João et. al.

Structural basis for sensory rhodopsin function
score: 2.3701898, BBA - Biomembranes, 2002, Pebay-Peyroula, Eva et. al.

Vibrio cholerae Toxin-Coregulated Pilus Structure Analyzed by Hydrogen/Deuterium Exchange Mass Spectrometry
score: 2.3696784, Structure, 2008, Li, Juliana et. al.

Protein-small molecule interactions in neocarzinostatin, the prototypical enediyne chromoprotein antibiotic.
score: 2.3686952, Chembiochem : a European journal of chemical biology, 2007, Baker, James R et. al.

Crystallographic analysis reveals the 12-fold symmetry of the bacteriophage φ29 connector particle 1 1 Edited by R. Huber
score: 2.3686361, Journal of Molecular Biology, 1998, Guasch, Alicia et. al.

Assembly of Post-Receptor Signaling Complexes for the Tumor Necrosis Factor Receptor Superfamily
score: 2.3684933, Advances in Protein Chemistry, 2004, Wu, Hao

Assembly of Post-Receptor Signaling Complexes for the Tumor Necrosis Factor Receptor Superfamily
score: 2.3684933, Advances in Protein Chemistry, 2004, Wu, Hao

Multivariate Analysis of Conserved Sequence–Structure Relationships in Kinesins: Coupling of the Active Site and a Tubulin-binding Sub-domain
score: 2.3684743, Journal of Molecular Biology, 2007, Grant, Barry J. et. al.

A novel "open-form" structure of sortaseC from Streptococcus suis.
score: 2.3682157, Proteins, 2011, Lu, Guangwen et. al.

Structural and BiochemicalConsequences of Disease-CausingMutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel
score: 2.3681566, Biochemistry, 2012, Inada, Hitoshi et. al.

Structure-based organic synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin
score: 2.3679074, Bioorganic & Medicinal Chemistry Letters, 2007, Hanessian, Stephen et. al.

Projection maps of three members of the KdgM outer membrane protein family
score: 2.3678621, Journal of Structural Biology, 2007, Signorell, Gian A. et. al.

Solution NMR structure of an immunodominant epitope of myelin basic protein. Conformational dependence on environment of an intrinsically unstructured protein.
score: 2.3672316, The FEBS journal, 2006, Farès, Christophe; Libich, David S; Harauz, George

Accessibility of selenomethionine proteins by total chemical synthesis: structural studies of human herpesvirus-8 MIP-II
score: 2.3663611, FEBS Letters, 1998, Shao, Weiping et. al.

The Structure of Phosphorylase Kinase Holoenzyme at 9.9 Å Resolution and Location of the Catalytic Subunit and the Substrate Glycogen Phosphorylase
score: 2.3660777, Structure, 2009, Vénien-Bryan, Catherine et. al.

Flanking Polyproline Sequences Inhibit β-Sheet Structure in Polyglutamine Segments by Inducing PPII-like Helix Structure
score: 2.365485, Journal of Molecular Biology, 2007, Darnell, Gregory et. al.

Structural studies on recombinant and point mutants of flavocytochrome b 2
score: 2.3651076, Biochimie, 1994, Tegoni, M.; Cambillau, C.

The structure of a designed diiron(III) protein: implications for cofactor stabilization and catalysis.
score: 2.3651037, Angewandte Chemie (International ed. in English), 2006, Wade, Herschel; Stayrook, Steven E; Degrado, William F

Rational Protein Crystallization by Mutational Surface Engineering
score: 2.3648878, Structure, 2004, Derewenda, Zygmunt S.

Structural insights into a novel histone demethylase PHF8.
score: 2.3644979, Cell research, 2010, Yu, Lin et. al.

Asparagine and glutamine: using hydrogen atom contacts in the choice of side-chain amide orientation 1 1 Edited by J. Thornton
score: 2.3642024, Journal of Molecular Biology, 1999, Word, J.Michael et. al.

Comparative analysis of thermoadaptation within the archaeal glyceraldehyde-3-phosphate dehydrogenases from mesophilic Methanobacterium bryantii and thermophilic Methanothermus fervidus.
score: 2.363118, Biopolymers, 2002, Charron, Christophe; Vitoux, Bernard; Aubry, André

Structure and Function of the Glucocorticoid Receptor Ligand Binding Domain
score: 2.3630959, Vitamins and Hormones, 2004, Bledsoe, Randy K; Stewart, Eugene L; Pearce, Kenneth H

Structure and Function of the Glucocorticoid Receptor Ligand Binding Domain
score: 2.3630959, Vitamins and Hormones, 2004, Bledsoe, Randy K; Stewart, Eugene L; Pearce, Kenneth H

Structure and Function of the Glucocorticoid Receptor Ligand Binding Domain
score: 2.3630959, Vitamins and Hormones, 2004, Bledsoe, Randy K; Stewart, Eugene L; Pearce, Kenneth H

Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization
score: 2.3621418, Bioorganic & Medicinal Chemistry, 2012, Davies, Nicholas G.M. et. al.

Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization
score: 2.3621418, Bioorganic & Medicinal Chemistry, 2012, Davies, Nicholas G.M. et. al.

Structure of the cholera toxin secretion channel in its closed state.
score: 2.3616791, Nature structural & molecular biology, 2010, Reichow, Steve L et. al.

The race-specific elicitor AVR9 of the tomato pathogen Cladosporium fulvum: a cystine knot protein
score: 2.3609244, FEBS Letters, 1997, Vervoort, Jacques et. al.

The race-specific elicitor AVR9 of the tomato pathogen Cladosporium fulvum: a cystine knot protein
score: 2.3609244, FEBS Letters, 1997, Vervoort, Jacques et. al.

Computational Biochemistry of Antibodies and T-Cell Receptors
score: 2.3604887, Advances in Protein Chemistry, 1996, Novotny, Jiri; Bajorath, Jürgen

Structural Characterization of the Natively Unfolded N-Terminal Domain of Human c-Src Kinase: Insights into the Role of Phosphorylation of the Unique Domain
score: 2.3602389, Journal of Molecular Biology, 2009, Pérez, Yolanda; Gairí, Margarida; Pons, Miquel; Bernadó, Pau

A general method for the unbiased improvement of solution NMR structures by the use of related X-Ray data, the AUREMOL-ISIC algorithm
score: 2.3600672, BMC Structural Biology, 2006, Brunner, Konrad et. al.

BioMagResBank
score: 2.3583425, Nucleic Acids Research, 2008, Ulrich, Eldon L. et. al.

The crystal structure of the catalytic domain of the site-specific recombination enzyme γδ resolvase at 2.7 Å resolution
score: 2.3576946, Cell, 1990, Sanderson, Mark R. et. al.

Structural and SAXS analysis of the budding yeast SHU-complex proteins
score: 2.3575921, FEBS Letters, 2012, She, Zhun et. al.

Zinc potentiates GluK3 glutamate receptor function by stabilizing the ligand binding domain dimer interface
score: 2.3567123, Neuron, 2012, Veran, Julien et. al.

Preliminary X-ray diffraction analysis of YcdB from Escherichia coli : a novel haem-containing and Tat-­secreted periplasmic protein with a potential role in iron transport
score: 2.3565744, Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2006, Cartron, Michaël L. et. al.

The benefits of atomic resolution
score: 2.356339, Current Opinion in Structural Biology, 1997, Dauter, Zbigniew; Lamzin, Victor S; Wilson, Keith S

A Structural Determinant for the Control of PIP 2 Sensitivity in G Protein-gated Inward Rectifier K + Channels
score: 2.355913, The Journal of Biological Chemistry, 2010, Inanobe, Atsushi et. al.

Restraints on backbone conformations in solid state NMR studies of uniformly labeled proteins from quantitative amide 15N–15N and carbonyl 13C–13C dipolar recoupling data
score: 2.3557906, Journal of Magnetic Resonance, 2012, Hu, Kan-Nian et. al.

Restraints on backbone conformations in solid state NMR studies of uniformly labeled proteins from quantitative amide 15N–15N and carbonyl 13C–13C dipolar recoupling data
score: 2.3557906, Journal of Magnetic Resonance, 2012, Hu, Kan-Nian et. al.

Restraints on backbone conformations in solid state NMR studies of uniformly labeled proteins from quantitative amide 15N–15N and carbonyl 13C–13C dipolar recoupling data
score: 2.3557906, Journal of Magnetic Resonance, 2012, Hu, Kan-Nian et. al.

Ribonuclease A suggests how proteins self-chaperone against amyloid fiber formation.
score: 2.3552987, Protein science : a publication of the Protein Society, 2012, Teng, Poh K et. al.

Identification of the PXW Sequence as a Structural Gatekeeper of the Headpiece C-terminal Subdomain Fold
score: 2.3548655, Journal of Molecular Biology, 2006, Vermeulen, Wim et. al.

Dynamic NMR Structures of [Rp]- and [Sp]-Phosphorothioated DNA-RNA Hybrids: Is Flexibility Required for RNase H Recognition?
score: 2.3536705, Biophysical Journal, 2003, Tonelli, Marco et. al.

The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation.
score: 2.3526074, The EMBO journal, 2003, Förster, Andreas; Whitby, Frank G; Hill, Christopher P

Crystal structure of human Intersectin-2L C2 domain
score: 2.3514583, Biochemical and Biophysical Research Communications, 2013, Zhang, Wei et. al.

Crystal structure of a zinc-containing glycerol dehydrogenase (TM0423) from Thermotoga maritima at 1.5 A resolution.
score: 2.351124, Proteins, 2003, Brinen, Linda S et. al.

Enterohaemorrhagic Escherichia Coli Exploits a Tryptophan Switch to Hijack Host F-Actin Assembly
score: 2.3506881, Structure, 2012, Aitio, Olli et. al.

Enterohaemorrhagic Escherichia Coli Exploits a Tryptophan Switch to Hijack Host F-Actin Assembly
score: 2.3506881, Structure, 2012, Aitio, Olli et. al.

Membrane protein SMP-1 is required for normal flagellum function in Leishmania.
score: 2.3504698, Journal of cell science, 2010, Tull, Dedreia et. al.

Molecular Architecture of the Yeast Monopolin Complex
score: 2.3496847, Cell Reports, 2012, Corbett, Kevin D.; Harrison, Stephen C.

Molecular Architecture of the Yeast Monopolin Complex
score: 2.3496847, Cell Reports, 2012, Corbett, Kevin D.; Harrison, Stephen C.

Insights into the Dynamics of Specific Telomeric Single-Stranded DNA Recognition by Pot1pN
score: 2.3495165, Journal of Molecular Biology, 2009, Croy, Johnny E.; Wuttke, Deborah S.

Large-Scale Conformational Flexibility Determines the Properties of AAA+ TIP49 ATPases
score: 2.3493674, Structure, 2012, Petukhov, Michael et. al.

The Orientation of a Tandem POTRA Domain Pair, of the Beta-Barrel Assembly Protein BamA, Determined by PELDOR Spectroscopy
score: 2.3492001, Structure, 2009, Ward, R. et. al.

Analysis of the Thermodynamics of Binding of an SH3 Domain to Proline-rich Peptides using a Chimeric Fusion Protein
score: 2.3484455, Journal of Molecular Biology, 2008, Candel, Adela M. et. al.

Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNA
score: 2.3483944, Structure, 2013, Liu, Minmin et. al.

Calcium-dependent Homoassociation of E-cadherin by NMR Spectroscopy: Changes in Mobility, Conformation and Mapping of Contact Regions
score: 2.3477976, Journal of Molecular Biology, 2002, Häussinger, Daniel et. al.

Insights into the Structure and Domain Flexibility of Full-Length Pro-Matrix Metalloproteinase-9/Gelatinase B
score: 2.3474937, Structure, 2007, Rosenblum, Gabriel et. al.

Three-dimensional structures of chimeric enzymes between Bacillus subtilis and Thermus thermophilus 3-isopropylmalate dehydrogenases.
score: 2.3469645, Protein engineering, 1994, Onodera, K et. al.

Combined spatial limitation around residues 16 and 108 of Plasmodium falciparum dihydrofolate reductase explains resistance to cycloguanil.
score: 2.3464482, Antimicrobial agents and chemotherapy, 2012, Vanichtanankul, Jarunee et. al.

Purification and crystallization of glycogen phosphorylase from Saccharomyces cerevisiae
score: 2.3457979, Journal of Molecular Biology, 1992, Rath, Virginia L.; Hwang, Peter K.; Fletterick, Robert J.

Structural analysis of bacteriophage T4 DNA replication: a review in the Virology Journal series on bacteriophage T4 and its relatives
score: 2.3457826, Virology Journal, 2010, Mueser, Timothy C et. al.

NMR solution structures of two mutants of desulforedoxin
score: 2.3452781, Journal of Inorganic Biochemistry, 2003, Goodfellow, B.J. et. al.

Steroid dehydrogenase structures, mechanism of action, and disease
score: 2.3447286, Vitamins and Hormones, 2000, Duax, William L.; Ghosh, Debashis; Pletnev, Vladimir

Steroid dehydrogenase structures, mechanism of action, and disease
score: 2.3447286, Vitamins and Hormones, 2000, Duax, William L.; Ghosh, Debashis; Pletnev, Vladimir

Steroid dehydrogenase structures, mechanism of action, and disease
score: 2.3447286, Vitamins and Hormones, 2000, Duax, William L.; Ghosh, Debashis; Pletnev, Vladimir

Anatomy of an Amyloidogenic Intermediate
score: 2.3439962, Structure, 2004, Armen, Roger S.; Alonso, Darwin O.V.; Daggett, Valerie

Rational engineering of human cytochrome P450 2B6 for enhanced expression and stability: importance of a Leu264->Phe substitution.
score: 2.3439919, Molecular pharmacology, 2007, Kumar, Santosh et. al.

Molecular basis of chromium insulin interactions
score: 2.3437063, Biochemical and Biophysical Research Communications, 2008, Sreekanth, R.; Pattabhi, Vasantha; Rajan, S.S.

Torsion angle dynamics: reduced variable conformational sampling enhances crystallographic structure refinement.
score: 2.343545, Proteins, 1994, Rice, L M; Brünger, A T

Structure and Function of Lipases
score: 2.342809, Advances in Protein Chemistry, 1994, Derewenda, Zygmunt S.

Crystallization and preliminary X-ray diffraction studies of coxsackievirus B1
score: 2.341236, Journal of Molecular Biology, 1992, Li, Thomas et. al.

The structure of bacterial outer membrane proteins
score: 2.3408149, BBA - Biomembranes, 2002, Schulz, Georg E.

Enhanced protein flexibility caused by a destabilizing amino acid replacement in BPTI 1 1 Edited by P.E. Wright
score: 2.3402148, Journal of Molecular Biology, 1997, Beeser, Scott A; Goldenberg, David P; Oas, Terrence G

Molecular Dynamics Studies of the Wild-Type and Double Mutant HIV-1 Integrase Complexed with the 5CITEP Inhibitor: Mechanism for Inhibition and Drug Resistance
score: 2.3399483, Biophysical Journal, 2003, Barreca, Maria L. et. al.

Adenine recognition: a motif present in ATP-, CoA-, NAD-, NADP-, and FAD-dependent proteins.
score: 2.3394671, Proteins, 2001, Denessiouk, K A; Rantanen, V V; Johnson, M S

When X-rays modify the protein structure: radiation damage at work
score: 2.3381137, Trends in Biochemical Sciences, 2005, Carugo, Oliviero; Carugo, Kristina Djinović

Structural flexibility of the methanogenic-type seryl-tRNA synthetase active site and its implication for specific substrate recognition.
score: 2.3376469, The FEBS journal, 2008, Bilokapic, Silvija et. al.

Solution structure of the splicing factor motif of the human Prp18 protein.
score: 2.3376423, Proteins, 2012, He, Fahu et. al.

Proline cis- trans Isomerization Controls Autoinhibition of a Signaling Protein
score: 2.3363797, Molecular Cell, 2007, Sarkar, Paramita et. al.

Solution Conformation and Heparin-induced Dimerization of the Full-length Extracellular Domain of the Human Amyloid Precursor Protein
score: 2.3363511, Journal of Molecular Biology, 2006, Gralle, Matthias et. al.

X-ray structures of transferrins and related proteins
score: 2.3362104, BBA - General Subjects, 2012, Mizutani, Kimihiko; Toyoda, Mayuko; Mikami, Bunzo

Discovery of 4-amino-5,6-biaryl-furo[2,3- d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR
score: 2.3360473, Bioorganic & Medicinal Chemistry Letters, 2007, DiMauro, Erin F. et. al.

Mutation of an essential glutamate residue in folylpolyglutamate synthetase and activation of the enzyme by pteroate binding
score: 2.3359747, Archives of Biochemistry and Biophysics, 2002, Sheng, Yi et. al.

Helix formation and the unfolded state of a 52-residue helical protein.
score: 2.3355397, Protein science : a publication of the Protein Society, 2004, Cao, Wei; Bracken, Clay; Kallenbach, Neville R; Lu, Min

A role for ring-closing metathesis in medicinal chemistry: Mimicking secondary architectures in bioactive peptides.
score: 2.335336, Medicinal research reviews, 2010, Pérez de Vega, María Jesús et. al.

Backbone and methyl dynamics of the regulatory domain of troponin C: anisotropic rotational diffusion and contribution of conformational entropy to calcium affinity 1 1 Edited by P. E. Wright
score: 2.3345585, Journal of Molecular Biology, 1998, Gagné, Stéphane M. et. al.

West Nile virus methyltransferase catalyzes two methylations of the viral RNA cap through a substrate-repositioning mechanism.
score: 2.3343209, Journal of virology, 2008, Dong, Hongping et. al.

NMR structures of anti-HIV d-peptides derived from the N-terminus of viral chemokine vMIP-II
score: 2.3342348, Biochemical and Biophysical Research Communications, 2005, Mori, Mayuko; Liu, Dongxiang; Kumar, Santosh; Huang, Ziwei

A Proposed Time-Resolved X-Ray Scattering Approach to Track Local and Global Conformational Changes in Membrane Transport Proteins
score: 2.3337459, Structure, 2008, Andersson, Magnus et. al.

Molecular Structure of the Collagen Triple Helix
score: 2.3336205, Advances in Protein Chemistry, 2005, Brodsky, Barbara; Persikov, Anton V.

Molecular Structure of the Collagen Triple Helix
score: 2.3336205, Advances in Protein Chemistry, 2005, Brodsky, Barbara; Persikov, Anton V.

Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034
score: 2.332228, Journal of Synchrotron Radiation, 2008, Madison, Vincent et. al.

Electron crystallography reveals the structure of metarhodopsin I.
score: 2.3312662, The EMBO journal, 2004, Ruprecht, Jonathan J et. al.

Structure of a Peptidoglycan Amidase Effector Targeted to Gram-Negative Bacteria by the Type VI Secretion System
score: 2.3308404, Cell Reports, 2012, Chou, Seemay et. al.

Structure of a Peptidoglycan Amidase Effector Targeted to Gram-Negative Bacteria by the Type VI Secretion System
score: 2.3308404, Cell Reports, 2012, Chou, Seemay et. al.

Hyaloperonospora arabidopsidis ATR1 effector is a repeat protein with distributed recognition surfaces.
score: 2.3304964, Proceedings of the National Academy of Sciences of the United States of America, 2011, Chou, Seemay et. al.

Electrostatically constrained α-helical peptide inhibits replication of HIV-1 resistant to enfuvirtide
score: 2.3290188, International Journal of Biochemistry and Cell Biology, 2009, Nishikawa, Hiroki et. al.

The influence of phosphorylation on the activity and structure of the neuronal IQ motif protein, PEP-19
score: 2.3284492, Brain Research, 2006, Dickerson, J. Bradley et. al.

Conformational Dynamics in the Selectivity Filter of KcsA in Response to Potassium Ion Concentration
score: 2.3282645, Journal of Molecular Biology, 2010, Bhate, Manasi P. et. al.

Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2
score: 2.3282064, Bioorganic & Medicinal Chemistry Letters, 2012, Labadie, Sharada et. al.

Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2
score: 2.3282064, Bioorganic & Medicinal Chemistry Letters, 2012, Labadie, Sharada et. al.

Structure-Based Discovery of C-2 Substituted Imidazo-pyrrolopyridine JAK1 Inhibitors with Improved Selectivity over JAK2
score: 2.3282064, Bioorganic & Medicinal Chemistry Letters, 2012, Labadie, Sharada et. al.

Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2
score: 2.3282064, Bioorganic & Medicinal Chemistry Letters, 2012, Labadie, Sharada et. al.

Protein engineering
score: 2.3271813, Current Opinion in Biotechnology, 1997,

NMR structure of the principal neutralizing determinant of HIV-1 displayed in filamentous bacteriophage coat protein 1 1 Edited by I. A. Wilson
score: 2.327056, Journal of Molecular Biology, 1997, Jelinek, Raz et. al.

Biochemical characterization and preliminary X-ray crystallographic study of the domains of human ZBP1 bound to left-handed Z-DNA
score: 2.3270151, BBA - Proteins and Proteomics, 2006, Ha, Sung Chul et. al.

Bridging the information gap: computational tools for intermediate resolution structure interpretation 1 1 Edited by W. Baumeister
score: 2.3269615, Journal of Molecular Biology, 2001, Jiang, Wen; Baker, Matthew L.; Ludtke, Steven J.; Chiu, Wah

Structural similarity of a developmentally regulated bacterial spore coat protein to beta gamma-crystallins of the vertebrate eye lens.
score: 2.3264171, Proceedings of the National Academy of Sciences of the United States of America, 1994, Bagby, S; Harvey, T S; Eagle, S G; Inouye, S; Ikura, M

Flap opening and dimer-interface flexibility in the free and inhibitor-bound HIV protease, and their implications for function
score: 2.3263263, Structure, 1999, Ishima, Rieko et. al.

The genesis of high-throughput structure-based drug discovery using protein crystallography
score: 2.3261782, Current Opinion in Chemical Biology, 2002, Kuhn, Peter et. al.

Control of eukaryotic membrane fusion by N-terminal domains of SNARE proteins
score: 2.3246243, BBA - Molecular Cell Research, 2003, Dietrich, Lars E.P et. al.

Solution structure of endothelin B receptor selective antagonist RES-701-1 determined by 1H NMR spectroscopy
score: 2.3228264, Bioorganic & Medicinal Chemistry, 1995, Katahira, Ritsuko et. al.

A flexible lid controls access to the active site in 1,3,8-trihydroxynaphthalene reductase
score: 2.3226056, FEBS Letters, 1997, Andersson, Arnold et. al.

A flexible lid controls access to the active site in 1,3,8-trihydroxynaphthalene reductase
score: 2.3226056, FEBS Letters, 1997, Andersson, Arnold et. al.

Structural bases for the interaction of frataxin with the central components of iron-sulphur cluster assembly.
score: 2.3208696, Nature communications, 2010, Prischi, Filippo et. al.

Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa
score: 2.3208485, FEBS Letters, 2012, Zhang, Heng; Gao, Zeng-Qiang; Su, Xiao-Dong; Dong, Yu-Hui

Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex.
score: 2.3201208, Proceedings of the National Academy of Sciences of the United States of America, 2011, Sato, Yusuke et. al.

Mass Spectrometry Guided In Situ Proteolysis to Obtain Crystals for X-Ray Structure Determination
score: 2.3199276, Journal of the American Society for Mass Spectrometry, 2010, Gheyi, Tarun et. al.

Cathepsin K Inhibitors: Their Potential as Anti-Osteoporosis Agents
score: 2.3195221, Progress in Medicinal Chemistry, 2004, Deaton, David N.; Kumar, Sanjay

Stable formation of a pyrimidine-rich loop hairpin in a cruciform promoter 1 1 Edited by I. Tinoco
score: 2.3186933, Journal of Molecular Biology, 1999, Chou, Shan-Ho; Tseng, Yu-Yu; Chu, Bi-Yun

Derivation of locally accurate spatial protein structure from NMR data
score: 2.3185253, Progress in Biophysics and Molecular Biology, 1993, Sherman, Simon A.; Johnson, Michael E.

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha.
score: 2.3183846, Journal of virology, 2011, Lienlaf, Maritza et. al.

PONDEROSA, an automated 3D-NOESY peak picking program, enables automated protein structure determination
score: 2.3182427, Bioinformatics, 2011, Lee, Woonghee et. al.

Molecular dynamics simulations of the coenzyme induced conformational changes of Mycobacterium tuberculosisl-alanine dehydrogenase
score: 2.3181562, Journal of Molecular Graphics and Modelling, 2012, Ling, Baoping et. al.

Molecular dynamics simulations of the coenzyme induced conformational changes of Mycobacterium tuberculosisl-alanine dehydrogenase
score: 2.3181562, Journal of Molecular Graphics and Modelling, 2012, Ling, Baoping et. al.

Residual dipolar couplings in nucleic acid structure determination
score: 2.3179148, Current Opinion in Structural Biology, 2002, MacDonald, Douglas; Lu, Ponzy

Benzo[ b]thiophene-based histone deacetylase inhibitors
score: 2.3172028, Bioorganic & Medicinal Chemistry Letters, 2007, Witter, David J. et. al.

Role of conserved nucleotides in building the 16 S rRNA binding site for ribosomal protein S15 1 1 Edited by J. Karn
score: 2.3169769, Journal of Molecular Biology, 2001, Serganov, Alexander et. al.

Mutation of Phe413 to Tyr in catalase KatE from Escherichia coli leads to side chain damage and main chain cleavage
score: 2.3150707, Archives of Biochemistry and Biophysics, 2012, Jha, Vikash; Donald, Lynda J.; Loewen, Peter C.

Structure, dynamics and electrostatics of the active site of glutaredoxin 3 from Escherichia coli: comparison with functionally related proteins 1 1 Edited by B. Honig
score: 2.3148326, Journal of Molecular Biology, 2001, Foloppe, Nicolas et. al.

Crystallography and the design of anti-AIDS drugs: conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors
score: 2.3140045, Progress in Biophysics and Molecular Biology, 2005, Das, Kalyan; Lewi, Paul J.; Hughes, Stephen H.; Arnold, Eddy

Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor
score: 2.3128774, Structure(London, England:1993), 2013, Gangloff, Monique et. al.

How Different are Structurally Flexible and Rigid Binding Sites? Sequence and Structural Features Discriminating Proteins that Do and Do not Undergo Conformational Change upon Ligand Binding
score: 2.3128323, Journal of Molecular Biology, 2007, Gunasekaran, Kannan; Nussinov, Ruth

Domain rotations between open, closed and bullet-shaped forms of the thermosome, an archaeal chaperonin 1 1 Edited by A. R. Fersht
score: 2.3112373, Journal of Molecular Biology, 2000, Schoehn, Guy et. al.

Structural Determination of Functional Units of the Nucleotide Binding Domain (NBD94) of the Reticulocyte Binding Protein Py235 of Plasmodium yoelii
score: 2.3111671, PLoS ONE, 2010, Grüber, Ardina et. al.

Peptide inhibitors of the malaria surface protein, apical membrane antigen 1: identification of key binding residues.
score: 2.3106677, Biopolymers, 2011, Lee, Erinna F et. al.

Application of the anomalous dispersion of X-rays to macromolecular crystallography
score: 2.3097672, Progress in Biophysics and Molecular Biology, 1995, Fourme, Roger; Shepard, William; Kahn, Richard

Tangled Up in Knots: Structures of Inactivated Forms of E. coli Class Ia Ribonucleotide Reductase
score: 2.3095369, Structure, 2012, Zimanyi, Christina M. et. al.

Crystal structure of inactive form of Rab3B
score: 2.3088064, Biochemical and Biophysical Research Communications, 2012, Zhang, Wei et. al.

Three-dimensional structure of the bacterial cell wall peptidoglycan.
score: 2.3086661, Proceedings of the National Academy of Sciences of the United States of America, 2006, Meroueh, Samy O et. al.

Insights into MAPK p 38 α DFG flip mechanism by accelerated molecular dynamics
score: 2.3084767, Bioorganic & Medicinal Chemistry, 2010, Filomia, Federico et. al.

The Folding Pathway of T4 Lysozyme: The High-resolution Structure and Folding of a Hidden Intermediate
score: 2.3073691, Journal of Molecular Biology, 2007, Kato, Hidenori; Feng, Hanqiao; Bai, Yawen

Structure of Sesbania mosaic virus at 3 Å resolution
score: 2.3067628, Biophysical Chemistry, 1997, Murthy, M.R.N. et. al.

Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitors
score: 2.3054552, Bioorganic & Medicinal Chemistry Letters, 2009, Chirapu, Srinivas Reddy et. al.

Wheel of Life, Wheel of Death: A Mechanistic Insight into Signaling by STAND Proteins
score: 2.3049439, Structure, 2009, Danot, Olivier et. al.

Three-dimensional structure of a type VI turn in a linear peptide in water solution Evidence for stacking of aromatic rings as a major stabilizing factor
score: 2.3047215, Journal of Molecular Biology, 1994, Yao, Jian; Dyson, H.Jane; Wright, Peter E.

X-ray diffraction study of di and tetra-ligated T-state hemoglobin from high salt crystals
score: 2.3044157, Journal of Molecular Biology, 1992, Abraham, Donald J. et. al.

GES-18, a new carbapenem-hydrolyzing GES-type β-lactamase from Pseudomonas aeruginosa that contains Ile80 and Ser170 residues.
score: 2.3037182, Antimicrobial agents and chemotherapy, 2012, Bebrone, Carine et. al.

Compensatory and Long-Range Changes in Picosecond–Nanosecond Main-Chain Dynamics upon Complex Formation: 15N Relaxation Analysis of the Free and Bound States of the Ubiquitin-like Domain of Human Plexin-B1 and the Small GTPase Rac1
score: 2.3034127, Journal of Molecular Biology, 2008, Bouguet-Bonnet, S.; Buck, M.

How Random are Intrinsically Disordered Proteins? A Small Angle Scattering Perspective
score: 2.3031694, Current Protein & Peptide Science, 2012, Receveur-Bréchot, Véronique; Durand, Dominique

Lipocalins as a scaffold
score: 2.3027292, Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology, 2000, Skerra, Arne

The interactions of antimicrobial peptides derived from lysozyme with model membrane systems
score: 2.3016712, BBA - Biomembranes, 2005, Hunter, Howard N. et. al.

CLOUDS, a protocol for deriving a molecular proton density via NMR.
score: 2.3011609, Proceedings of the National Academy of Sciences of the United States of America, 2002, Grishaev, Alexander; Llinás, Miguel

Evolution of function in protein superfamilies, from a structural perspective 1 1 Edited by A. R. Fersht
score: 2.3006286, Journal of Molecular Biology, 2001, Todd, Annabel E; Orengo, Christine A; Thornton, Janet M

Yeast RNA Polymerase II at 5 Å Resolution
score: 2.3005937, Cell, 1999, Fu, Jianhua et. al.

Isolation and immunological characterization of a novel Cladosporium herbarum allergen structurally homologous to the α/β hydrolase fold superfamily
score: 2.3000664, Molecular Immunology, 2010, Rid, Raphaela et. al.

Fluorophore Labeled Kinase Detects Ligands That Bind within the MAPK Insert of p38α Kinase
score: 2.2995839, PLoS ONE, 2012, Getlik, Matthäus et. al.

Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model.
score: 2.2993975, Molecular and cellular biology, 2006, Tong, Kit I et. al.

Stabilisation of a (βα) 8-Barrel Protein Designed from Identical Half Barrels
score: 2.2993177, Journal of Molecular Biology, 2007, Seitz, Tobias et. al.

Backbone dynamics of a short PU.1 ETS domain 1 1 Edited by P. E. Wright
score: 2.2992043, Journal of Molecular Biology, 1999, Jia, Xin et. al.

Structural basis of the properties of an industrially relevant thermophilic xylanase.
score: 2.2991428, Proteins, 1997, Harris, G W et. al.

Selenium Derivatization of Nucleic Acids for Phase and Structure Determination in Nucleic Acid X-ray Crystallography
score: 2.298519, International Journal of Molecular Sciences, 2008, Sheng, Jia; Huang, Zhen

Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites 1 1 Edited by I. A. Wilson
score: 2.2971595, Journal of Molecular Biology, 2001, West, Anthony P. et. al.

Vertebrate-type and plant-type ferredoxins: crystal structure comparison and electron transfer pathway modelling 1 1 Edited by R. Huber
score: 2.2965569, Journal of Molecular Biology, 1999, Müller, Jürgen J et. al.

Identification of a Collapsed Intermediate with Non-native Long-range Interactions on the Folding Pathway of a Pair of Fyn SH3 Domain Mutants by NMR Relaxation Dispersion Spectroscopy
score: 2.2964016, Journal of Molecular Biology, 2006, Neudecker, Philipp et. al.

Intermediate Filament Protein Structure Determination
score: 2.2948089, Methods in Cell Biology, 2004, Strelkov, Sergei V. et. al.

Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation
score: 2.2947575, Structure(London, England:1993), 2012, Bunney, Tom D. et. al.

Extending the Understanding of Mutagenicity: Structural Insights into Primer-extension Past a Benzo[ a]pyrene Diol Epoxide-DNA adduct
score: 2.2945786, Journal of Molecular Biology, 2003, Perlow, Rebecca A.; Broyde, Suse

The structure and mechanism of bacterial type I signal peptidases
score: 2.2915712, Pharmacology and Therapeutics, 2000, Paetzel, Mark; Dalbey, Ross E; Strynadka, Natalie C.J

Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification
score: 2.2909761, Structure, 2012, Jansen, Silvia et. al.

New Structural and Functional Contexts of the Dx[DN]xDG Linear Motif: Insights into Evolution of Calcium-Binding Proteins
score: 2.2905257, PLoS ONE, 2011, Rigden, Daniel J. et. al.

Prediction of the mechanism of action of omuralide ( clasto-lactacystin β-lactone) on human cathepsin A based on a structural model of the yeast proteasome β5/PRE2-subunit/omuralide complex
score: 2.2892932, BBA - Proteins and Proteomics, 2006, Aikawa, Sei-ichi et. al.

NMR structure of antibiotics plipastatins A and B from Bacillus subtilis inhibitors of phospholipase A 2
score: 2.2885337, FEBS Letters, 2000, Volpon, Laurent; Besson, Françoise; Lancelin, Jean-Marc

Backbone Dynamics of Escherichia coli Ribonuclease HI: Correlations with Structure and Function in an Active Enzyme
score: 2.2880912, Journal of Molecular Biology, 1995, Mandel, Arthur M.; Akke, Mikael; Palmer, III, Arthur G.

Localization of bound water in the solution structure of a complex of the erythroid transcription factor GATA-1 with DNA
score: 2.2873347, Structure, 1994, Clore, G.Marius et. al.

Molecular Dynamics Simulations of the Complex between Human U1A Protein and Hairpin II of U1 Small Nuclear RNA and of Free RNA in Solution
score: 2.2872422, Biophysical Journal, 1999, Tang, Yun; Nilsson, Lennart

NF45 dimerizes with NF90, Zfr and SPNR via a conserved domain that has a nucleotidyltransferase fold
score: 2.2860978, Nucleic Acids Research, 2012, Wolkowicz, Urszula M.; Cook, Atlanta G.

Rapid-access, high-throughput synchrotron crystallography for drug discovery
score: 2.2854719, Trends in Pharmacological Sciences, 2012, Wasserman, Stephen R. et. al.

Rapid-access, high-throughput synchrotron crystallography for drug discovery
score: 2.2854719, Trends in Pharmacological Sciences, 2012, Wasserman, Stephen R. et. al.

Robust structure-based resonance assignment for functional protein studies by NMR
score: 2.2842547, Journal of Biomolecular Nmr, 2009, Stratmann, Dirk; Guittet, Eric; van Heijenoort, Carine

Pseudouridine Synthases
score: 2.2831399, Chemistry & Biology, 2006, Hamma, Tomoko; Ferré-D'Amaré, Adrian R.

Structure-based discovery of a family of synthetic cyclophilin inhibitors showing a cyclosporin-A phenotype in Caenorhabditis elegans
score: 2.2829809, Biochemical and Biophysical Research Communications, 2007, Yang, Yuande et. al.

Motions and Negative Cooperativity Between p97 Domains Revealed by Cryo-electron Microscopy and Quantised Elastic Deformational Model
score: 2.282053, Journal of Molecular Biology, 2003, Beuron, Fabienne et. al.

Electron Microscopy and 3D Reconstruction Reveals Filamin Ig-Domain Binding to F-Actin
score: 2.2813803, Journal of Molecular Biology, 2012, Suphamungmee, Worawit et. al.

Module-module interactions in the cell binding region of fibronectin: stability, flexibility and specificity 1 1 Edited by A. R. Fersht
score: 2.281273, Journal of Molecular Biology, 1997, Spitzfaden, Claus et. al.

Correlation of binding constants and molecular modelling of inhibitors in the active sites of aldose reductase and aldehyde reductase
score: 2.2811019, Bioorganic & Medicinal Chemistry, 2009, Carbone, Vincenzo et. al.

Structure and dynamics of the deoxyguanosine-sensing riboswitch studied by NMR-spectroscopy
score: 2.2804096, Nucleic Acids Research, 2011, Wacker, Anna et. al.

Three protein kinase structures define a common motif
score: 2.2798336, Structure, 1994, Taylor, Susan Serota; Radzio-Andzelm, Elzbieta

Structure-Function Perturbation and Dissociation of Tetrameric Urate Oxidase by High Hydrostatic Pressure
score: 2.2797296, Biophysical Journal, 2010, Girard, Eric et. al.

Molecular basis of glyphosate resistance-different approaches through protein engineering.
score: 2.2786161, The FEBS journal, 2011, Pollegioni, Loredano; Schonbrunn, Ernst; Siehl, Daniel

Deuterium-proton exchange on the native wild-type transthyretin tetramer identifies the stable core of the individual subunits and indicates mobility at the subunit interface 1 1 Edited by P. E. Wright
score: 2.2768739, Journal of Molecular Biology, 2000, Liu, Kai et. al.

Strategies in RNA Crystallography
score: 2.2763845, Methods in Enzymology, 2009, Reyes, Francis E.; Garst, Andrew D.; Batey, Robert T.

Induced Fit in Arginine Kinase
score: 2.2759789, Biophysical Journal, 2000, Zhou, Genfa; Ellington, W. Ross; Chapman, Michael S.

Low resolution solution structure of the Bacillus subtilis glucose permease IIA domain derived from heteronuclear three-dimensional NMR spectroscopy
score: 2.2746666, FEBS Letters, 1992, Fairbrother, Wayne J. et. al.

New variation on a theme: structure and mechanism of action of hydrolytic antibody 7F11, an aspartate rich relation of catalytic antibodies 17E8 and 29G11
score: 2.2746657, Journal of Immunological Methods, 2002, Cross, Simon S.J et. al.

In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors.
score: 2.2739553, Cancer research, 2007, Sharp, Swee Y et. al.

The noncatalytic triad of alpha-amylases: a novel structural motif involved in conformational stability.
score: 2.2734287, Proteins, 2008, Marx, Jean-Claude et. al.

Biophysical Analysis of Kindlin-3 Reveals an Elongated Conformation and Maps Integrin Binding to the Membrane-distal β-Subunit NP X Y Motif
score: 2.2732362, The Journal of Biological Chemistry, 2012, Yates, Luke A. et. al.

New insights about HERG blockade obtained from protein modeling, potential energy mapping, and docking studies
score: 2.2730292, Bioorganic & Medicinal Chemistry, 2006, Farid, Ramy et. al.

Protein conformational substates from X-ray crystallography
score: 2.2723243, Progress in Biophysics and Molecular Biology, 1996, Rejto, Paul A.; Freer, Stephan T.

Nucleosomes in Solution Exist as a Mixture of Twist-defect States
score: 2.272295, Journal of Molecular Biology, 2005, Edayathumangalam, Rajeswari S. et. al.

Structure of Yeast RNA Polymerase II in Solution
score: 2.2721652, Structure, 2002, Craighead, John L; Chang, Wei-hau; Asturias, Francisco J

Structure and activity of CPNGRC: a modified CD13/APN peptidic homing motif.
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score: 2.2709928, Biopolymers, 2000, Albrizio, S et. al.